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KCNK12 Gene

protein-coding   GIFtS: 51
GCID: GC02M047747

Potassium Channel, Subfamily K, Member 12

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Potassium Channel, Subfamily K, Member 121 2     K2p12.12
Tandem Pore Domain Halothane-Inhibited Potassium Channel 22 3     Potassium Channel Subfamily K Member 122
THIK-22 3     Tandem Pore Domain Potassium Channel THIK-22
THIK22 5     

External Ids:    HGNC: 62741   Entrez Gene: 566602   Ensembl: ENSG000001842617   OMIM: 6073665   UniProtKB: Q9HB153   

Export aliases for KCNK12 gene to outside databases

Previous GC identifers: GC02M047763 GC02M047916 GC02M047722 GC02M047659 GC02M047483


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KCNK12 Gene:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming
P domains. The product of this gene has not been shown to be a functional channel, however, it may require other
non-pore-forming proteins for activity. (provided by RefSeq, Jul 2008)

GeneCards Summary for KCNK12 Gene:
KCNK12 (potassium channel, subfamily K, member 12) is a protein-coding gene. Diseases associated with KCNK12 include idiopathic generalized epilepsy, and maturity-onset diabetes of the young. GO annotations related to this gene include voltage-gated ion channel activity and potassium channel activity. An important paralog of this gene is KCNK15.

UniProtKB/Swiss-Prot: KCNKC_HUMAN, Q9HB15
Function: Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to
associate with another protein to form a functional channel (By similarity)

Gene Wiki entry for KCNK12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCNK12 gene promoter:
         AhR   Max1   NF-1   AP-1   Pax-5   HNF-3beta   Arnt   MZF-1   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCNK12 promoter sequence
   Search Chromatin IP Primers for KCNK12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCNK12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p16.3   Ensembl cytogenetic band:  2p21   HGNC cytogenetic band: 2p16.3

KCNK12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNK12 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M047747:  view genomic region     (about GC identifiers)

Start:
47,743,720 bp from pter      End:
47,798,078 bp from pter
Size:
54,359 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KCNKC_HUMAN, Q9HB15 (See protein sequence)
Recommended Name: Potassium channel subfamily K member 12  
Size: 430 amino acids; 46889 Da
Subunit: Heterodimer (Potential)

Explore the universe of human proteins at neXtProt for KCNK12: NX_Q9HB15

Explore proteomics data for KCNK12 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn78
  • Modification sites at PhosphoSitePlus

  • See KCNK12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071338.1  
    ENSEMBL proteins: 
     ENSP00000327611  

    KCNK12 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    KCN: Potassium channels
    KCNK: Voltage-gated ion channels / Potassium channels, Two-P

    IUPHAR Guide to PHARMACOLOGY protein family classification: K2P12.1
    Two-P potassium channels

    3 InterPro protein domains:
     IPR003280 2pore_dom_K_chnl
     IPR005410 2pore_dom_K_chnl_THIK
     IPR013099 2pore_dom_K_chnl_dom

    Graphical View of Domain Structure for InterPro Entry Q9HB15

    ProtoNet protein and cluster: Q9HB15

    3 Blocks protein domains:
    IPB003280 Two pore domain K+ channel signature
    IPB005410 THIK K+ channel signature
    IPB013099 Ion transport 2


    UniProtKB/Swiss-Prot: KCNKC_HUMAN, Q9HB15
    Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family


    KCNK12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCNKC_HUMAN, Q9HB15
    Function: Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to
    associate with another protein to form a functional channel (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005244voltage-gated ion channel activity IEA--
    GO:0005267potassium channel activity IEA--
         
    KCNK12 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCNK12
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCNK12
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate KCNK12 (see all 10):
    hsa-miR-579 hsa-miR-1261 hsa-miR-3653 hsa-miR-518b hsa-miR-518a-3p hsa-miR-4282 hsa-miR-3658 hsa-miR-518d-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK12

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KCNKC_HUMAN, Q9HB15: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    KCNK12 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KCNK12 About    
    See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for KCNK12 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCNK12
    Interactions:

        Search GeneGlobe Interaction Network for KCNK12

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for KCNK12 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Cesium chloridePotassium channel blocker; neuroprotective[7647-17-8]
    YS-035 hydrochlorideInhibits K+ outward/pacemaker current[33978-72-2]
    BL 1249Putative K2P2.1 (TREK-1) channel opener[18200-13-0]
    DMP 543K+ channel blocker and potent ACh release enhancer[160588-45-4]
    Tetraethylammonium chlorideNon-selective K+ channel blocker[56-34-8]

    1 IUPHAR Ligand for KCNK12 (K2P12.1)    About this table
    LigandTypeActionAffinityPubmed IDs
    halothane
    InhibitorNone--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KCNK12 gene: 
    NM_022055.1  

    Unigene Cluster for KCNK12:

    Potassium channel, subfamily K, member 12
    Hs.591586  [show with all ESTs]
    Unigene Representative Sequence: BC047749
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000327876(uc002rwb.3) ENST00000493527
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate KCNK12 (see all 10):
    hsa-miR-579 hsa-miR-1261 hsa-miR-3653 hsa-miR-518b hsa-miR-518a-3p hsa-miR-4282 hsa-miR-3658 hsa-miR-518d-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK12
    Primer
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    OriGene qPCR primer pairs and template standards for KCNK12
    OriGene qSTAR qPCR primer pairs in human, mouse for KCNK12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCNK12
      QuantiTect SYBR Green Assays in human, mouse, rat KCNK12
      QuantiFast Probe-based Assays in human, mouse, rat KCNK12

    Additional mRNA sequence: 

    AF287302.1 BC047749.1 

    3 DOTS entries:

    DT.75135164  DT.95157677  DT.40226063 

    Selected AceView cDNA sequences (see all 35):

    BI966799 AF287302 BI962982 CK903603 NM_022055 AW135862 BC047749 BG398375 
    BX282643 BX342864 BX397064 BI757775 BF663150 CD516991 BI517462 AI969059 
    AI825537 BG208703 BG216088 BX342523 BI547637 BG207245 BI262061 BX342863 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KCNK12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAACCGGC
    KCNK12 Expression
    About this image


    KCNK12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             TGFbeta3+BMP7-induced chondrocytes
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             TGFbeta3+BMP7-induced chondrocytes
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Ventral/hypothalamic-like neurons
     
     Neural Crest (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Primitive Streak (Early Embryonic Tissues)
             Primitive streak-like cells
    KCNK12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCNK12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591586
        Custom PCR Arrays for KCNK12
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KCNK12 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kcnk121 , 5 potassium channel, subfamily K, member 121, 5 96.2(n)1
    99.07(a)1
      17 (57.87 cM)5
    2107411  NM_199251.11  NP_954859.11 
     877458375 
    chicken
    (Gallus gallus)
    Aves KCNK121 potassium channel, subfamily K, member 12 73.47(n)
    78.34(a)
      428554  XM_003640904.2  XP_003640952.2 
    lizard
    (Anolis carolinensis)
    Reptilia KCNK126
    potassium channel, subfamily K, member 12
    73(a)
    1 ↔ 1
    1(254990917-254991252)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kcnk121 potassium channel, subfamily K, member 12 66.33(n)
    77.08(a)
      100494329  XM_002935380.2  XP_002935426.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5591531 potassium channel subfamily K member 12-like 68.94(n)
    72.22(a)
      559153  XM_682469.4  XP_687561.2 
    worm
    (Caenorhabditis elegans)
    Secernentea twk-123
    twk-141
    potassium channel protein3
    twk-141
    37(a)3
    44.63(n)1
    37.67(a)1
      V(12390060-12391487)3
    1796991  NM_001269485.11  NP_001256414.11 


    ENSEMBL Gene Tree for KCNK12 (if available)
    TreeFam Gene Tree for KCNK12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KCNK12 gene
    KCNK152  KCNK52  KCNK162  KCNK32  KCNK92  KCNK62  KCNK22  KCNK102  
    KCNK72  KCNK172  KCNK42  KCNK132  KCNK12  
    1 SIMAP similar gene for KCNK12 using alignment to 1 protein entry:     KCNKC_HUMAN:
    KCNK13

    KCNK12 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KCNK12 (see all 895)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1493478461,2
    --47747441(+) CAAATA/CTGGGG 1 -- ds50010--------
    rs3703002061,2
    C--47747523(+) GTGGC-/TGGGG 
            
    TGTTC
    1 -- ds50010--------
    rs1383599311,2
    C--47747524(+) TGGCT-/GG    
       GGGGG
    GTTCT
    1 -- ds50010--------
    rs1449483061,2
    --47747560(+) TGGCT-/GGTCCC 1 -- ds50010--------
    rs1885312541,2
    --47747647(+) AAATGC/TTGAGG 1 -- ds50010--------
    rs1446563101,2
    C--47747764(+) CGGTAC/TGCCCT 1 -- ds50010--------
    rs22781391,2
    C,F,H--47748292(-) CTCGGC/TGCCGA 2 G syn1 ese33Minor allele frequency- T:0.39NA EA 124
    rs1158629261,2
    C,F--47748388(+) GCGCAG/ACAGCG 2 /C syn13Minor allele frequency- A:0.00EU NA 3663
    rs2017302631,2
    --47748470(+) AAATGC/GAGCAC 2 S C mis10--------
    rs778832121,2
    C,F--47748487(+) AGCAGG/AATGAA 2 /I syn14Minor allele frequency- A:0.01WA NA 4796

    HapMap Linkage Disequilibrium report for KCNK12 (47743720 - 47798078 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for KCNK12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675502CNV Deletion23128226
    nsv2717CNV Insertion18451855
    esv29460CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KCNK12
    DNA2.0 Custom Variant and Variant Library Synthesis for KCNK12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607366    OMIM disorders: --

    10 diseases for KCNK12:    
    About MalaCards
    idiopathic generalized epilepsy    maturity-onset diabetes of the young    vitiligo    migraine
    cholera    alzheimer's disease    pancreatitis    neuronitis
    hepatitis    endotheliitis


    KCNK12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KCNK12
    Human Genome Epidemiology (HuGE) Navigator: KCNK12 (1 document)

    Export disorders for KCNK12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KCNK12 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with KCNK12)
        Utopia: connect your pdf to the dynamic
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    1. THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. (PubMed id 11060316)1, 2, 3 Rajan S.... Derst C. (J. Biol. Chem. 2001)
    2. Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8. (PubMed id 19890347)1, 4 Birlea S.A....Spritz R.A. (J. Invest. Dermatol. 2010)
    3. A high-density association screen of 155 ion transport genes for involvement with common migraine. (PubMed id 18676988)1, 4 Nyholt D.R....Palotie A. (Hum. Mol. Genet. 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney. (PubMed id 18209473)1, 9 Theilig F....Derst C. (Cell. Physiol. Biochem. 2008)
    6. Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane. (PubMed id 24163367)1 Chatelain F.C....Lesage F. (J. Biol. Chem. 2013)
    7. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PubMed id 22005930)4 Hollingworth P....Williams J. (Mol. Psychiatry 2012)
    8. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (BMC Med. Genet. 2007)
    9. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (Cell 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56660 HGNC: 6274 AceView: KCNK12 Ensembl:ENSG00000184261 euGenes: HUgn56660
    ECgene: KCNK12 H-InvDB: KCNK12

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KCNK12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for KCNK12 gene:
    Search GeneIP for patents involving KCNK12

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