Aliases for KCNJ15 Gene
Aliases for KCNJ15 Gene
- Potassium Voltage-Gated Channel Subfamily J Member 15 2 3 5
- Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 2 3
- Potassium Channel, Inwardly Rectifying Subfamily J Member 15 3 4
- Inward Rectifier K(+) Channel Kir1.3 3 4
- Inward Rectifier K(+) Channel Kir4.2 3 4
- ATP-Sensitive Inward Rectifier Potassium Channel 15 3
External Ids for KCNJ15 Gene
- HGNC: 6261
- Entrez Gene: 3772
- Ensembl: ENSG00000157551
- OMIM: 602106
- UniProtKB: Q99712
Previous GeneCards Identifiers for KCNJ15 Gene
- GC21P036206
- GC21P036289
- GC21P038549
- GC21P038550
- GC21P039628
- GC21P025098
- GC21P039529
Summaries for KCNJ15 Gene
-
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2013]
GeneCards Summary for KCNJ15 Gene
KCNJ15 (Potassium Voltage-Gated Channel Subfamily J Member 15) is a Protein Coding gene. Diseases associated with KCNJ15 include Leber Congenital Amaurosis 16 and Corneal Dystrophy, Schnyder Type. Among its related pathways are Inwardly rectifying K+ channels and GABA receptor activation. GO annotations related to this gene include potassium channel activity and inward rectifier potassium channel activity. An important paralog of this gene is KCNJ10.
UniProtKB/Swiss-Prot for KCNJ15 Gene
-
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
-
The inward-rectifier potassium channel family (also known as 2-TM channels) include the strong inward-rectifier channels (Kir2.x), the G-protein-activated inward-rectifier channels (Kir3.x) and the ATP-sensitive channels (Kir6.x), which combine with sulphonylurea receptors.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNJ15 Gene
Genomics for KCNJ15 Gene
Regulatory Elements for KCNJ15 Gene
Enhancers for KCNJ15 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH21G038227 | 1.2 | FANTOM5 ENCODE dbSUPER | 32.1 | +71.4 | 71367 | 1.5 | RBBP5 DPF2 E2F1 GATA3 CTBP1 HDAC2 BCL11A NBN TRIM28 | KCNJ15 GC21M038236 DSCR10 |
| GH21G038348 | 1.9 | FANTOM5 Ensembl ENCODE dbSUPER | 19.6 | +193.9 | 193922 | 5.2 | HDGF ZNF143 ZNF207 KLF7 FOS ZNF263 SP3 TSHZ1 REST ZNF518A | KCNJ15 HMGN1 LINC01423 ETS2 GC21M038398 GC21M038399 |
| GH21G038257 | 1.5 | FANTOM5 Ensembl ENCODE dbSUPER | 17.3 | +101.5 | 101524 | 3.1 | CTCF CBX8 JUND GATA2 BHLHE40 FOS BMI1 MAFK RAD21 NFE2L2 | KCNJ15 SPATA20P1 LOC105372801 |
| GH21G038239 | 1.3 | Ensembl ENCODE dbSUPER | 16.7 | +84.4 | 84420 | 3.8 | SIN3A RBBP5 PAX8 ZNF335 GATA3 CTBP1 GLIS2 ZFHX2 POLR2A ZBTB48 | KCNJ15 SPATA20P1 LOC105372801 |
| GH21G038221 | 1.4 | FANTOM5 ENCODE dbSUPER | 14.5 | +64.7 | 64652 | 0.6 | ESRRA TBL1XR1 BACH1 BMI1 EBF1 RELA ARID3A ZSCAN29 FOS RELB | KCNJ15 GC21M038236 DSCR10 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around KCNJ15 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the KCNJ15 gene promoter:
Regulatory Element Products
Genomic Location for KCNJ15 Gene
- Chromosome:
- 21
- Start:
- 38,157,034 bp from pter
- End:
- 38,307,357 bp from pter
- Size:
- 150,324 bases
- Orientation:
- Plus strand
Genomic View for KCNJ15 Gene
Genes around KCNJ15 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 21q22.13 by Ensembl
- 21q22.13-q22.2 by Entrez Gene
- 21q22.13-q22.2 by HGNC
KCNJ15 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KCNJ15 Gene
Proteins for KCNJ15 Gene
-
Protein details for KCNJ15 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99712-KCJ15_HUMAN
- Recommended name:
- ATP-sensitive inward rectifier potassium channel 15
- Protein Accession:
- Q99712
- D3DSH5
- O00564
- Q96L28
- Q99446
Protein attributes for KCNJ15 Gene
- Size:
- 375 amino acids
- Molecular mass:
- 42577 Da
- Quaternary structure:
-
- Interacts with PATJ.
Protein Expression for KCNJ15 Gene
Post-translational modifications for KCNJ15 Gene
Other Protein References for KCNJ15 Gene
- ENSEMBL proteins:
-
- ENSP00000381899
- ENSP00000381901
- ENSP00000381902
- ENSP00000381904
- ENSP00000381905
- ENSP00000381907
- ENSP00000381911
- ENSP00000392951
- ENSP00000400849
- ENSP00000413013
- ENSP00000414487
- ENSP00000447111
- ENSP00000448676
- ENSP00000448770
- ENSP00000448886
- ENSP00000449140
- ENSP00000449419
- ENSP00000450254
- ENSP00000479100
- ENSP00000484960
- ENSP00000331698
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for KCNJ15
-
Abcam antibodies for KCNJ15
- Invitrogen Antibodies for KCNJ15
- antibodies-online Antibodies for KCNJ15: See all 37
- Search GeneTex for Antibodies for KCNJ15
-
Santa Cruz Biotechnology (SCBT) Antibodies for KCNJ15
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for KCNJ15
- Origene Custom Protein Services for KCNJ15
- Novus Biologicals proteins for KCNJ15
- antibodies-online Proteins for KCNJ15: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for KCNJ15
-
Abcam proteins for KCNJ15
Assay Products
- antibodies-online Kits for KCNJ15: See all 4
No data available for DME Specific Peptides for KCNJ15 Gene
Domains & Families for KCNJ15 Gene
Gene Families for KCNJ15 Gene
- HGNC:
- IUPHAR :
Protein Domains for KCNJ15 Gene
Suggested Antigen Peptide Sequences for KCNJ15 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q99712UniProtKB/Swiss-Prot:
KCJ15_HUMAN :- Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ15 subfamily.
- Family:
-
- Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ15 subfamily.
Function for KCNJ15 Gene
Molecular function for KCNJ15 Gene
- GENATLAS Biochemistry:
- potassium non voltage-gated channel,inwardly rectifying subfamily J member 15 Kir4.2,expressed in kidney and brain
- UniProtKB/Swiss-Prot Function:
- Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005242 | inward rectifier potassium channel activity | TAS | 8995301 |
| GO:0005244 | voltage-gated ion channel activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 9647694 |
| GO:0015467 | G-protein activated inward rectifier potassium channel activity | TAS | -- |
Phenotypes for KCNJ15 Gene
- MGI mutant phenotypes for KCNJ15:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for KCNJ15:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased G1 DNA content
- Decreased homologous recombination repair frequency
Animal Models for KCNJ15 Gene
- MGI Knock Outs for KCNJ15:
-
- Kcnj15 tm1Dgen
Animal Model Products
-
Taconic Biosciences Mouse Models for KCNJ15
-
ViGene Biosciences lentiviral particle packaged cDNA for KCNJ15 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for KCNJ15 gene
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CRISPR Products
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-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNJ15
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miRNA for KCNJ15 Gene
- miRTarBase miRNAs that target KCNJ15
-
- hsa-mir-9-5p (MIRT021341)
- hsa-mir-98-5p (MIRT027409)
- hsa-mir-498 (MIRT569798)
- hsa-mir-298 (MIRT569799)
- hsa-mir-548ao-3p (MIRT569800)
- hsa-mir-4684-5p (MIRT687789)
- hsa-mir-6827-3p (MIRT687790)
- hsa-mir-340-3p (MIRT687791)
- hsa-mir-433-5p (MIRT687792)
- hsa-mir-6771-3p (MIRT687793)
- hsa-mir-548x-3p (MIRT687794)
- hsa-mir-548j-3p (MIRT687795)
- hsa-mir-548aq-3p (MIRT687796)
- hsa-mir-548am-3p (MIRT687797)
- hsa-mir-548aj-3p (MIRT687798)
- hsa-mir-548ah-3p (MIRT687799)
- hsa-mir-548ae-3p (MIRT687800)
- hsa-mir-548z (MIRT687801)
- hsa-mir-548h-3p (MIRT687802)
- hsa-mir-548d-3p (MIRT687803)
- hsa-mir-548bb-3p (MIRT687804)
- hsa-mir-548ac (MIRT687805)
miRNA Products
- Search ViGene Biosciences for KCNJ15
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for KCNJ15
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Cell Line Products
-
Horizon Cell Lines for KCNJ15
-
ViGene Biosciences adenoviral particle packaged cDNA for KCNJ15 gene
-
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-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KCNJ15 Gene
Localization for KCNJ15 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNJ15 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 8995301 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for KCNJ15 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Inwardly rectifying K+ channels | ||
| 2 | GABA receptor activation | ||
| 3 | Transmission across Chemical Synapses |
.62
|
|
| 4 | Salivary secretion | ||
| 5 | Dopamine-DARPP32 Feedback onto cAMP Pathway | ||
Pathways by source for KCNJ15 Gene
11 Reactome pathways for KCNJ15 Gene
1 KEGG pathway for KCNJ15 Gene
1 Qiagen pathway for KCNJ15 Gene
Interacting Proteins for KCNJ15 Gene
Selected Interacting proteins:
ENSP00000331698
Q99712-KCJ15_HUMAN
for KCNJ15 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006813 | potassium ion transport | TAS | 8995301 |
| GO:0010107 | potassium ion import | IBA | -- |
| GO:0034765 | regulation of ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for KCNJ15 Gene
Drugs & Compounds for KCNJ15 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Yohimbine | Approved, Vet_approved | Pharma | Antagonist, Target | 28 | ||
| Glyburide | Approved | Pharma | Channel blocker | Kir6 (KATP) channel blocker | 114 | |
| Nicorandil | Approved | Pharma | Activator | Potassium channel activator, Kir6 (KATP) channel opener and NO donor | 17 | |
| Magnesium | Nutra | 0 | ||||
| Levcromakalim | Pharma | Kir6 (KATP) channel opener; active enantiomer of cromakalim (Cat. No. 1377) | 0 |
(5) Tocris Compounds for KCNJ15 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Glibenclamide | Kir6 (KATP) channel blocker | 10238-21-8 |
| Levcromakalim | Kir6 (KATP) channel opener; active enantiomer of cromakalim (Cat. No. 1377) | 94535-50-9 |
| Nicorandil | Kir6 (KATP) channel opener and NO donor | 65141-46-0 |
| Tertiapin-Q | Selective blocker of inward-rectifier K+ channels | 252198-49-5 |
| Y-26763 | Kir6 (KATP) channel opener | 127408-31-5 |
Transcripts for KCNJ15 Gene
mRNA/cDNA for KCNJ15 Gene
- (15) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (67) Selected AceView cDNA sequences:
- (21) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KCNJ15 Gene
CRISPR Products
-
OriGene CRISPR knockouts for KCNJ15
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNJ15
- GenScript: Design CRISPR guide RNA sequences for KCNJ15
miRNA Products
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Inhibitory RNA Products
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Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||
| SP8: | - |
Expression for KCNJ15 Gene
mRNA differential expression in normal tissues according to GTEx for KCNJ15 Gene
This gene is overexpressed in Whole Blood (x26.9) and Kidney - Cortex (x7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KCNJ15 Gene
NURSA nuclear receptor signaling pathways regulating expression of KCNJ15 Gene:
KCNJ15SOURCE GeneReport for Unigene cluster for KCNJ15 Gene:
Hs.411299Evidence on tissue expression from TISSUES for KCNJ15 Gene
- Kidney(4.7)
- Thyroid gland(2.3)
- Stomach(2)
Primer Products
-
OriGene qPCR primer pairs for KCNJ15
-
OriGene qPCR primer pairs and template standards for KCNJ15
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNJ15 Gene
Orthologs for KCNJ15 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KCNJ15 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | KCNJ15 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | KCNJ15 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Kcnj15 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Kcnj15 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | KCNJ15 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | KCNJ15 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | KCNJ15 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | KCNJ15 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kcnj15 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC68935 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC572476 34 |
|
||
| KCNJ15 35 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Irk3 36 |
|
|
|
| Irk2 35 |
|
ManyToMany | |||
| Ir 35 |
|
ManyToMany |
- Species where no ortholog for KCNJ15 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KCNJ15 Gene
Paralogs for KCNJ15 Gene
(16) SIMAP similar genes for KCNJ15 Gene using alignment to 9 proteins:
Variants for KCNJ15 Gene
| SNP ID | Clin | Chr 21 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs199857043 | A breast cancer sample | 38,299,472(+) | TGTTC(A/G)CTGCC | reference, missense | |
| rs1000013062 | -- | 38,253,773(+) | CAGTA(G/T)TCAGA | intron-variant, nc-transcript-variant | |
| rs1000020096 | -- | 38,234,878(+) | AAACG(C/T)AAATC | intron-variant | |
| rs1000058461 | -- | 38,251,499(+) | CCATA(C/T)GGAGC | intron-variant, nc-transcript-variant | |
| rs1000074273 | -- | 38,235,245(+) | TCTTA(-/T)TTTTT | intron-variant, downstream-variant-500B |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv22065 | CNV | loss | 19812545 |
| esv2677092 | CNV | deletion | 23128226 |
| esv33823 | CNV | loss | 17666407 |
| esv3387523 | CNV | insertion | 20981092 |
| esv3389609 | CNV | insertion | 20981092 |
| esv3647000 | CNV | loss | 21293372 |
| nsv1058886 | CNV | gain | 25217958 |
| nsv3514 | CNV | insertion | 18451855 |
| nsv474591 | CNV | novel sequence insertion | 20440878 |
| nsv819873 | CNV | loss | 19587683 |
Residual Variation Intolerance Score:
47.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.64;
65.67% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KCNJ15 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNJ15 Gene
Disorders for KCNJ15 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| leber congenital amaurosis 16 |
|
|
| corneal dystrophy, schnyder type |
|
|
Search KCNJ15 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for KCNJ15
No data available for UniProtKB/Swiss-Prot and Genatlas for KCNJ15 Gene
Publications for KCNJ15 Gene
- A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1). (PMID: 9299242) Gosset P. … Creau N. (Genomics 1997) 2 3 4 22 64
- Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3). (PMID: 8995301) Shuck M.E. … Bienkowski M.J. (J. Biol. Chem. 1997) 2 3 4 64
- Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus. (PMID: 20085713) Okamoto K. … Tokunaga K. (Am. J. Hum. Genet. 2010) 3 46 64
- International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. (PMID: 16382105) Kubo Y. … Vandenberg C.A. (Pharmacol. Rev. 2005) 2 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
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- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for KCNJ15
- Sino Biological Human cDNA Clone for KCNJ15
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for KCNJ15
- Novus Biologicals proteins for KCNJ15
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for KCNJ15
- Abcam proteins for KCNJ15
- Search for Assays for KCNJ15 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Taconic Biosciences Mouse Models for KCNJ15
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for KCNJ15: See all 37
- antibodies-online Kits for KCNJ15: See all 4
- antibodies-online Proteins for KCNJ15: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for KCNJ15
- Search GeneTex for Proteins for KCNJ15
- ViGene Biosciences adenoviral particle packaged cDNA for KCNJ15 gene
- ViGene Biosciences lentiviral particle packaged cDNA for KCNJ15 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KCNJ15 gene
- Search ViGene Biosciences for KCNJ15
- Santa Cruz Biotechnology (SCBT) Antibodies for KCNJ15
- Search Santa Cruz Biotechnology (SCBT) for KCNJ15 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KCNJ15
- Horizon Cell Lines for KCNJ15
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNJ15
- VectorBuilder custom plasmid, inducible vectors for KCNJ15
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNJ15
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for KCNJ15 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer