V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

KCNJ12 Gene

protein-coding GIFtS: 56

GC17P021220

potassium inwardly-rectifying channel, subfamily J, member 12
(Previous names: potassium inwardly-rectifying channel, subfamily J, inhibitor 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: KCNJN1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ14167 ^²
IRK2 ^¹, ², ³
KCNJN1 ^², ³, ⁵
Kir2.2 ^¹, ²
Kir2.2v ^¹, ², ³
hIRK ^²
hIRK1 ^¹, ²
hkir2.2x ^²
kcnj12x ^²

Descriptions
ATP-sensitive inward rectifier potassium channel 12 ^²
Inward rectifier K(+) channel Kir2.2 ^³
Potassium channel, inwardly rectifying subfamily J member 12 ^³
potassium inwardly-rectifying channel, subfamily J, inhibitor 1 ^¹, ²
potassium inwardly-rectifying channel, subfamily J, member 12 ^²

External Ids
HGNC: 6258¹
Entrez Gene: 3768²
UniProtKB: Q14500³
Ensembl: ENSG00000184185⁷

Search outside databases for aliases for KCNJ12 gene

Previous GC identifers: GC17P021500 GC17P022929 GC17P021184 GC17P021441 GC17P021259

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KCNJ12:

This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This

protein is thought to be one of multiple inwardly rectifying channels which contribute to the

cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome

region on chromosome 17. [provided by RefSeq]

UniProtKB/Swiss-Prot: IRK12_HUMAN, Q14500

Function: Probably participates in establishing action potential waveform and excitability of

neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater

tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence

is regulated by the concentration of extracellular potassium; as external potassium is raised, the

voltage range of the channel opening shifts to more positive voltages. The inward rectification is

mainly due to the blockage of outward current by internal magnesium. Can be blocked by

extracellular barium and cesium

Gene Wiki entry for KCNJ12

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the KCNJ12 gene

Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.1

KCNJ12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P021220: (about GC identifiers)

Start:	21,220,292 bp from pter
End:	21,263,772 bp from pter
Size:	43,481 bases
Orientation:	plus strand

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: IRK12_HUMAN, Q14500 (See protein sequence)

Recommended Name: ATP-sensitive inward rectifier potassium channel 12

Size: 433 amino acids; 49001 Da

Subunit: Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and

APBA1 plays a key role in its localization and trafficking (By similarity)

Subcellular location: Membrane; Multi-pass membrane protein

Secondary accessions: O43401 Q15756 Q8NG63

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_066292.2

ENSEMBL proteins:

ENSP00000328150

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Kir2.2)
	Human Recombinant Proteins from Abnova (KCNJ12)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0030315	T-tubule	IEA	--
GO:0030425	dendrite	IEA	--
GO:0043025	cell soma	IEA	--

About this table

Antibodies for KCNJ12:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of KCNJ12
	Sigma-Aldrich Antibodies for KCNJ12
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Kir2.2), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for KCNJ12

Assays for KCNJ12:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q14500

ProtoNet protein and cluster: Q14500

3 Blocks protein families:

IPB001838 Inward rectifier K+ channel superfamily signature

IPB003272 Kir2.2 inward rectifier K+ channel signature

IPB013673 Inward rectifier potassium channel N-terminal

UniProtKB/Swiss-Prot: IRK12_HUMAN, Q14500

Similarity: Belongs to the inward rectifier-type potassium channel family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNJ12)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNJ12)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_021012

Applied Biosystems Silencer® siRNAs for KCNJ12

Sigma-Aldrich siRNA and siRNA Panels for KCNJ12

Sigma-Aldrich shRNA Panels and shRNA for KCNJ12

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for KCNJ12
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_021012
Myc/DDK tagged cDNA clone in CMV expression vector: NM_021012
untagged cDNA clone in CMV expression vector: NM_021012

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_021012

UniProtKB/Swiss-Prot: IRK12_HUMAN, Q14500

Function: Probably participates in establishing action potential waveform and excitability of

neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater

tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence

is regulated by the concentration of extracellular potassium; as external potassium is raised, the

voltage range of the channel opening shifts to more positive voltages. The inward rectification is

mainly due to the blockage of outward current by internal magnesium. Can be blocked by

extracellular barium and cesium

Genatlas biochemistry entry for KCNJ12:

potassium non voltage-gated channel,inwardly rectifying,subfamily J,alpha subunit KIR2.2,unlikely

to be involved in the Smith-Magenis syndrome

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Kcnj12):

5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005242	inward rectifier potassium channel activity	TAS	7859381
GO:0005244	voltage-gated ion channel activity	IEA	--
GO:0005515	protein binding	IEA	--
GO:0008200	ion channel inhibitor activity	TAS	8647284
GO:0015459	potassium channel regulator activity	TAS	8647284

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for KCNJ12

5/13 Interacting proteins for KCNJ12 (ENSP00000328150³) via UniProtKB, MINT, and/or STRING (see all 13 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LIN7C	ENSP00000278193³	STRING (score=.986)
DLG1	ENSP00000345731³	STRING (score=.985)
LIN7A	ENSP00000261203³	STRING (score=.984)
APBA1	ENSP00000265381³	STRING (score=.908)
CASK	ENSP00000367405³	STRING (score=.908)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0006813	potassium ion transport	TAS	7859381 8647284
GO:0006936	muscle contraction	TAS	7859381
GO:0008015	blood circulation	NAS	7859381
GO:0008016	regulation of heart contraction	TAS	7859381

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for KCNJ12 available from Tocris Bioscience

Compound	Action	CAS number
ZM 226600	KATP channel opener	[147695-92-9]
Minoxidil	K+ channel (KATP) opener	[38304-91-5]
PNU 37883 hydrochloride	Vascular KATP channel blocker	[57568-80-6]
Diazoxide	Blocks desensitization of AMPA receptors	[364-98-7]
Y-27152	Prodrug of KATP channel opener Y-26763; orally active in vivo	[127408-30-4]

About this table

1 Novoseek chemical compound relationship for KCNJ12 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
potassium	55.86	5	12417321 (2), 9533018 (1), 15276477 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNJ12)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNJ12)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_021012

Sigma-Aldrich siRNA and siRNA Panels for KCNJ12

Sigma-Aldrich shRNA Panels and shRNA for KCNJ12

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_021012

REFSEQ mRNAs for KCNJ12 gene:

NM_021012.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_021012

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_021012
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_021012
                                 untagged cDNA clone in CMV expression vector: NM_021012

20 AceView cDNA sequences:

NM_021012 BX279845 CD673578 BE550570 AW299543 AB182123 F29406 BE783053

AW299888 AI916525 BC027982 BV189339 BX387181 BE552277 AF005214 BM692647

L36069 AW297073 BX345071 BG332575

highest scoring ESTs for KCNJ12:

L36069 AF005214 AI916525 AW297073 AW299543 AW299888 BC027982 BE550570 BE552277 BM692647

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000331718

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KCNJ12 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KCNJ12

¹ / ² / ³

7 probe-sets matching KCNJ12 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34537_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	L36069	1.00	1.00	1.00	1
232289_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BF237871	0.40	0.67	0.55	1
207110_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_021012	0.60	1.00	0.82	1
208567_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002244	0.20	1.00	0.72	1
232289_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
207110_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
208567_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTATTTTCAA
Expression variation in blood from EXPOLDB for KCNJ12

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KCNJ12 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KCNJ12¹	--	potassium inwardly-rectifying channel, subfamily J, more	91.47(n) 97.85(a)	403760 XM_546667.2 XP_546667.2
chimpanzee (Pan troglodytes)	KCNJ12¹	--	potassium inwardly-rectifying channel, subfamily J, more	98.77(n) 98.15(a)	746628 XM_001154349.1 XP_001154349.1
cow (Bos taurus)	KCNJ12¹	--	potassium inwardly-rectifying channel, subfamily J, more	90.55(n) 96.25(a)	538479 NM_001024690.1 NP_001019861.1
rat (Rattus norvegicus)	Kcnj12¹	--	potassium inwardly-rectifying channel, subfamily J, more	89.38(n) 97.42(a)	117052 NM_053981.1 NP_446433.1
mouse (Mus musculus)	Kcnj12^{1, 5}	11 (34.15 cM)⁵	potassium inwardly-rectifying channel, subfamily J, more^{1, 5}	89.46(n)¹ 97.19(a)¹	16515¹ NM_010603.4¹ NP_034733.2¹ AB035889⁵ AK017299⁵ (see all 11)

About this table Species with no ortholog for KCNJ12

ENSEMBL Gene Tree for KCNJ12

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KCNJ12 gene

KCNJ4² KCNJ2² KCNJ14²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/770 NCBI SNPs in KCNJ12 are shown (see all 770 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 65)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2002591^1,2	A,C,F,H	21263829(-)	`CAGCAC/TGCTGT`	1	--	ng3¹		9		EU EA WA	2306
	rs4985866^1,2	A,C,F,H	21259992(+)	`ACCAGA/GTCGAC`	1	I/V	mis¹		11		EU EA WA NA	972
--	rs7213608^1,2	A,C,F,H	21219882(+)	`GTGTGT/CACATG`	1	--	ng5¹		4		EU EA WA	418
--	rs1714864^1,2	A,C,F	21259714(-)	`CCACCG/AGGCAC`	1	L/P	mis¹ ese³		1		MN	184
	rs1657742^1,2	A,C,H	21259823(+)	`GCACAG/CACGCT`	1	H/Q	mis¹ ese³		2		MN WA	304
--	rs3752032^1,2	C,F	21259264(+)	`CAGCCG/AGGCCA`	1	Q/R	mis¹ ese³		8		EA NA EU WA	2050
--	rs9908707^1,2	A,C	21252504(+)	`GTACCA/GTGCCC`	1	--	ut5¹ ese³		0	--	--	--	--
--	rs9889444^1,2	A,C	21252452(+)	`TCCAGC/TTGGTG`	1	--	ut5¹		0	--	--	--	--
--	rs1714904^1,2	A,C	21252525(-)	`TTCTAC/TGTAAT`	1	--	ut5¹ ese³		0	--	--	--	--
--	rs7218814^1,2	A,C	21220198(+)	`TAGGCG/TGGTGC`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for KCNJ12 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602323

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/30 PubMed articles for KCNJ12 gene (see all 30 ):

Identification of human Kir2.2 (KCNJ12) gene encoding functional inward rectifier potassium channel in both mammalian cells and Xenopus oocytes. (PubMed id 12417321)^{1, 2, 3, 4} Kaibara M....Taniyama K. (2002)
Cloning and functional expression of an inwardly rectifying K+ channel from human atrium. (PubMed id 7859381)^{2, 3, 4} Wible B.A.... Brown A.M. (1995)
International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. (PubMed id 16382105)^{2, 3} Kubo Y....Vandenberg C.A. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
An alternate promoter directs expression of a truncated, muscle- specific isoform of the human ankyrin 1 gene. (PubMed id 9430667)^{3, 4} Gallagher P.G. and Forget B.G. (1998)
Kir2.2v: a possible negative regulator of the inwardly rectifying K+ channel Kir2.2. (PubMed id 8647284)^{3, 4} Namba N.... Seino S. (1996)
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2. (PubMed id 15958527)^{1, 3} Fang Y....Levitan I. (2005)
The inwardly rectifying potassium channel subunit Kir2.2v (KCNJN1) maps to 17p11.2-->p11.1. (PubMed id 9533018)^{1, 3} Namba N....Seino Y. (1997)
Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1. (PubMed id 16258766)^{1, 3} Kiesecker C....Karle C.A. (2006)
Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery. (PubMed id 12598232)^{1, 3} Karkanis T....Sims S.M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3768	HGNC: 6258	AceView: KCNJ12	Ensembl:ENSG00000184185	euGenes: HUgn3768
ECgene: KCNJ12	H-InvDB: KCNJ12

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for KCNJ12	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for KCNJ12
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KCNJ12:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KCNJ12-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KCNJ12		Antibodies for KCNJ12
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KCNJ12		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (KCNJ12)
	Search for Antibodies
	Chimera RNAi (KCNJ12)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Kir2.2)
	Antibodies (Kir2.2)

Search OriGene for KCNJ12

Tocris compounds for KCNJ12

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for KCNJ12

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
KCNJ12 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

KCNJ12 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for KCNJ12

Summaries
for KCNJ12

Genomic Location
for KCNJ12

Proteins
for KCNJ12

Protein Domains/
Families
for KCNJ12

Gene Function
for KCNJ12

Pathways & Interactions
for KCNJ12

Drugs & Compounds
for KCNJ12

Transcripts
for KCNJ12

Expression
for KCNJ12

Orthologs
for KCNJ12

Paralogs
for KCNJ12

SNPs/Variants
for KCNJ12

Disorders & Mutations
for KCNJ12

Medical News
for KCNJ12

Publications
for KCNJ12

Search for KCNJ12

Genome Databases showing KCNJ12

Other Databases showing KCNJ12

Specialized Databases showing KCNJ12

Licensable Technologies
for KCNJ12

Services
for KCNJ12

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KCNJ12 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor KCNJ12

Summariesfor KCNJ12

Genomic Locationfor KCNJ12

Proteinsfor KCNJ12

Protein Domains/Familiesfor KCNJ12

Gene Functionfor KCNJ12

Pathways & Interactionsfor KCNJ12

Drugs & Compoundsfor KCNJ12

Transcriptsfor KCNJ12

Expression for KCNJ12

Orthologsfor KCNJ12

Paralogsfor KCNJ12

SNPs/Variantsfor KCNJ12

Disorders & Mutationsfor KCNJ12

Medical Newsfor KCNJ12

Publicationsfor KCNJ12

Search for KCNJ12

Genome Databases showing KCNJ12

Other Databases showing KCNJ12

Specialized Databases showing KCNJ12

Licensable Technologiesfor KCNJ12

Servicesfor KCNJ12

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KCNJ12

Summaries
for KCNJ12

Genomic Location
for KCNJ12

Proteins
for KCNJ12

Protein Domains/
Families
for KCNJ12

Gene Function
for KCNJ12

Pathways & Interactions
for KCNJ12

Drugs & Compounds
for KCNJ12

Transcripts
for KCNJ12

Expression
for KCNJ12

Orthologs
for KCNJ12

Paralogs
for KCNJ12

SNPs/Variants
for KCNJ12

Disorders & Mutations
for KCNJ12

Medical News
for KCNJ12

Publications
for KCNJ12

Licensable Technologies
for KCNJ12

Services
for KCNJ12