Aliases for KCNIP2 Gene
Aliases for KCNIP2 Gene
External Ids for KCNIP2 Gene
- HGNC: 15522
- Entrez Gene: 30819
- Ensembl: ENSG00000120049
- OMIM: 604661
- UniProtKB: Q9NS61
Previous GeneCards Identifiers for KCNIP2 Gene
- GC10M102478
- GC10M102819
- GC10M103716
- GC10M103250
- GC10M103575
- GC10M097216
Summaries for KCNIP2 Gene
-
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNIP2 Gene
KCNIP2 (Potassium Voltage-Gated Channel Interacting Protein 2) is a Protein Coding gene. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22 and Brugada Syndrome. Among its related pathways are Cardiac conduction and Antiarrhythmic Pathway, Pharmacodynamics. GO annotations related to this gene include calcium ion binding and protein N-terminus binding. An important paralog of this gene is KCNIP4.
UniProtKB/Swiss-Prot for KCNIP2 Gene
-
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity).
-
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNIP2 Gene
Genomics for KCNIP2 Gene
Regulatory Elements for KCNIP2 Gene
Enhancers for KCNIP2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around KCNIP2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the KCNIP2 gene promoter:
Regulatory Element Products
Genomic Location for KCNIP2 Gene
- Chromosome:
- 10
- Start:
- 101,825,974 bp from pter
- End:
- 101,843,920 bp from pter
- Size:
- 17,947 bases
- Orientation:
- Minus strand
Genomic View for KCNIP2 Gene
Genes around KCNIP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q24.32 by Ensembl
- 10q24.32 by Entrez Gene
- 10q24.32 by HGNC
KCNIP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KCNIP2 Gene
Proteins for KCNIP2 Gene
-
Protein details for KCNIP2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NS61-KCIP2_HUMAN
- Recommended name:
- Kv channel-interacting protein 2
- Protein Accession:
- Q9NS61
- A6NJE5
- A8MQ75
- Q3YAC6
- Q3YAC8
- Q3YAC9
- Q7Z6F1
- Q96K86
- Q96T41
- Q96T42
- Q96T43
- Q96T44
- Q9H0N4
- Q9HD10
- Q9HD11
- Q9NS60
- Q9NY10
- Q9NZI1
Protein attributes for KCNIP2 Gene
- Size:
- 270 amino acids
- Molecular mass:
- 30907 Da
- Quaternary structure:
-
- Component of heteromultimeric potassium channels. Identified in potassium channel complexes containing KCND1, KCND2, KCND3, KCNIP1, KCNIP2, KCNIP3, KCNIP4, DPP6 and DPP10 (By similarity). The KCND2-KCNIP2 channel complex contains four KCND2 and four KCNIP2 subunits (PubMed:14623880, PubMed:14980201). Interacts with KCND2 (PubMed:10676964, PubMed:14623880, PubMed:14980201). Isoform 1 and isoform 3 interact with KCND3 isoform 1. Probably part of a complex consisting of KCNIP1, KCNIP2 isoform 3 and KCND2. At least isoform 2 and isoform 3 can self-associate to form homodimers and homotetramers. Isoform 3 interacts with KCNIP1 in a calcium-dependent manner.
Protein Expression for KCNIP2 Gene
Post-translational modifications for KCNIP2 Gene
- Palmitoylated. Palmitoylation enhances association with the plasma membrane.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for KCNIP2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for KCNIP2
- Invitrogen Antibodies for KCNIP2
- antibodies-online Antibodies for KCNIP2: See all 116
- GeneTex KCNIP2 antibody for KCNIP2
-
Santa Cruz Biotechnology (SCBT) Antibodies for KCNIP2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for KCNIP2
- Origene Custom Protein Services for KCNIP2
- antibodies-online Proteins for KCNIP2: See all 10
- Search antibodies-online for peptides
- Search GeneTex for Proteins for KCNIP2
Assay Products
No data available for DME Specific Peptides for KCNIP2 Gene
Domains & Families for KCNIP2 Gene
Gene Families for KCNIP2 Gene
Protein Domains for KCNIP2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for KCNIP2 Gene
- GenScript: Design optimal peptide antigens:
-
- Kv channel interacting protein 2 (A6QL43_HUMAN)
- cDNA FLJ37349 fis, clone BRAMY2021746, highly similar to Kv channel-interacting protein 2 (B3KSZ5_HUMAN)
- Potassium channel-interacting protein 2 (KCIP2_HUMAN)
- Kv channel interacting protein 2 transcript variant 9 (Q09MK0_HUMAN)
- Potassium channel interacting protein 2 (Q3YAC6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9NS61- Family:
-
- Belongs to the recoverin family.
Function for KCNIP2 Gene
Molecular function for KCNIP2 Gene
- UniProtKB/Swiss-Prot Function:
- Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005250 | contributes_to A-type (transient outward) potassium channel activity | TAS | 26016905 |
| GO:0005267 | potassium channel activity | IEA | -- |
| GO:0005509 | calcium ion binding | TAS | 11287421 |
| GO:0005515 | protein binding | IPI | 14623880 |
| GO:0015459 | potassium channel regulator activity | IDA | 21493962 |
Phenotypes for KCNIP2 Gene
- MGI mutant phenotypes for KCNIP2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for KCNIP2:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Synthetic lethal with c-Myc after tamoxifen stimulation
- Decreased shRNA abundance
- Weakly decreased NFAT1-GFP nuclear translocation
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Increased Nanog expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for KCNIP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNIP2
- GenScript: Design CRISPR guide RNA sequences for KCNIP2
miRNA for KCNIP2 Gene
- miRTarBase miRNAs that target KCNIP2
miRNA Products
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Inhibitory RNA Products
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Clone Products
-
OriGene ORF clones in human for KCNIP2
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for KCNIP2
Cell Line Products
-
Horizon Cell Lines for KCNIP2
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KCNIP2 Gene
Localization for KCNIP2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNIP2 Gene
- Isoform 1: Cell membrane; Lipid-anchor. Note=Detected on lipid rafts (By similarity). {ECO:0000250 UniProtKB:Q9JM59}.
- Isoform 2: Cell membrane; Lipid-anchor.
- Isoform 6: Cell membrane; Lipid-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 2 |
| cytosol | 2 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | 11287421 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0008076 | voltage-gated potassium channel complex | IDA,NAS | 11287421 |
| GO:0016020 | membrane | IEA | -- |
| GO:0034705 | potassium channel complex | TAS | 26016905 |
Pathways & Interactions for KCNIP2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cardiac conduction | ||
| 2 | Antiarrhythmic Pathway, Pharmacodynamics | ||
Pathways by source for KCNIP2 Gene
3 Reactome pathways for KCNIP2 Gene
1 PharmGKB pathway for KCNIP2 Gene
Interacting Proteins for KCNIP2 Gene
Selected Interacting proteins:
ENSP00000420040
Q9NS61-KCIP2_HUMAN
for KCNIP2 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005513 | detection of calcium ion | TAS | 10676964 |
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006813 | potassium ion transport | TAS | 11287421 |
| GO:0006936 | muscle contraction | NAS | 11287421 |
No data available for SIGNOR curated interactions for KCNIP2 Gene
Drugs & Compounds for KCNIP2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Potassium | Approved | Pharma | 0 | |||
| 4-Aminopyridine | Approved | Pharma | Pore Blocker | potassium channel-blocking agent, Non-selective KV channel blocker | 69 | |
| calcium | Nutra | 0 | ||||
| E-4031 dihydrochloride | Pharma | KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | 0 | |||
| Linopirdine dihydrochloride | Pharma | KV7 (KCNQ) channel blocker | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| HMR 1556 |
|
223749-46-0 |
|
|
(5) Tocris Compounds for KCNIP2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-Aminopyridine | Non-selective KV channel blocker | 504-24-5 |
| E-4031 dihydrochloride | KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | 113559-13-0 |
| HMR 1556 | Potent and selective Iks channel blocker | 223749-46-0 |
| Linopirdine dihydrochloride | KV7 (KCNQ) channel blocker | 113168-57-3 |
| XE 991 dihydrochloride | Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents | 122955-13-9 |
Transcripts for KCNIP2 Gene
mRNA/cDNA for KCNIP2 Gene
- (13) REFSEQ mRNAs :
- (27) Additional mRNA sequences :
- (77) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KCNIP2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for KCNIP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNIP2
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miRNA Products
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Inhibitory RNA Products
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- Browse OriGene Inhibitory RNA Products For KCNIP2
Clone Products
-
OriGene ORF clones in human for KCNIP2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for KCNIP2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for KCNIP2
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP12: |
Expression for KCNIP2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Eye (Sensory Organs)
- GABAergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- GABAergic Amacrine Cells Inner Nuclear Layer
- Neural Tube (Nervous System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for KCNIP2 Gene
This gene is overexpressed in Heart - Atrial Appendage (x7.3), Brain - Nucleus accumbens (basal ganglia) (x6.5), Heart - Left Ventricle (x6.5), Brain - Putamen (basal ganglia) (x6.0), and Brain - Caudate (basal ganglia) (x5.1).
This gene is overexpressed in Retina (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KCNIP2 Gene
NURSA nuclear receptor signaling pathways regulating expression of KCNIP2 Gene:
KCNIP2SOURCE GeneReport for Unigene cluster for KCNIP2 Gene:
Hs.97044mRNA Expression by UniProt/SwissProt for KCNIP2 Gene:
Q9NS61-KCIP2_HUMAN
Tissue specificity:
Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
Evidence on tissue expression from TISSUES for KCNIP2 Gene
- Nervous system(4.9)
- Heart(4.7)
- Muscle(4.7)
- Kidney(4.2)
Primer Products
-
OriGene qPCR primer pairs for KCNIP2
-
OriGene qPCR primer pairs and template standards for KCNIP2
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNIP2 Gene
Orthologs for KCNIP2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KCNIP2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | KCNIP2 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | KCHIP2 35 |
|
OneToOne | |
| KCNIP2 34 |
|
||||
| mouse (Mus musculus) |
Mammalia | Kcnip2 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC100911951 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KCNIP2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | KCNIP2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | KCNIP2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | KCNIP2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kcnip2 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100003947 34 |
|
||
| kcnip2 35 |
|
OneToMany | |||
| KCNIP2 (1 of 2) 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5890 36 35 |
|
||
| CG42683 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | ncs-7 35 |
|
ManyToMany | |
| ncs-4 35 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | FRQ1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for KCNIP2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for KCNIP2 Gene
Paralogs for KCNIP2 Gene
(15) SIMAP similar genes for KCNIP2 Gene using alignment to 4 proteins:
Variants for KCNIP2 Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000017419 | -- | 101,827,192(+) | CTTCA(A/G)CTCCA | intron-variant, downstream-variant-500B, utr-variant-3-prime | |
| rs1000049837 | -- | 101,826,893(+) | CTTGT(C/G)CCCCT | intron-variant, utr-variant-3-prime | |
| rs1000283419 | -- | 101,840,513(+) | ACGCT(A/G)GCTAC | intron-variant, nc-transcript-variant, upstream-variant-2KB | |
| rs1000521020 | -- | 101,835,839(+) | TCACA(A/G)TAAGC | intron-variant, upstream-variant-2KB | |
| rs1000616254 | -- | 101,838,959(+) | AGTGC(C/T)GTGGG | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1126267 | CNV | deletion | 24896259 |
| nsv951004 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
60.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.67;
14.28% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KCNIP2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KCNIP2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNIP2 Gene
Disorders for KCNIP2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spinocerebellar ataxia type 19/22 |
|
|
| brugada syndrome |
|
|
Search KCNIP2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for KCNIP2
No data available for UniProtKB/Swiss-Prot and Genatlas for KCNIP2 Gene
Publications for KCNIP2 Gene
- Structure, alternative splicing, and expression of the human and mouse KCNIP gene family. (PMID: 16112838) Pruunsild P. … Timmusk T. (Genomics 2005) 3 4 22 64
- Modulation of Kv4.3 current by accessory subunits. (PMID: 12297301) Deschenes I. … Tomaselli G.F. (FEBS Lett. 2002) 3 4 22 64
- Molecular cloning and expression of the novel splice variants of K(+) channel-interacting protein 2. (PMID: 11263977) Ohya S. … Imaizumi Y. (Biochem. Biophys. Res. Commun. 2001) 3 4 22 64
- Modulation of A-type potassium channels by a family of calcium sensors. (PMID: 10676964) An W.F. … Rhodes K.J. (Nature 2000) 2 3 4 64
- [Atrial myocytes KChIP2 mRNA expression in rheumatic heart disease patients with atrial fibrillation]. (PMID: 19927631) Tan X.Q. … Zeng X.R. (Zhonghua Xin Xue Guan Bing Za Zhi 2009) 3 22 64
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- Search Santa Cruz Biotechnology (SCBT) for KCNIP2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KCNIP2
- Horizon Cell Lines for KCNIP2
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNIP2
- VectorBuilder custom plasmid, inducible vectors for KCNIP2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNIP2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for KCNIP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer