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KCNIP1 Gene

protein-coding GIFtS: 54

GC05P169716

Kv channel interacting protein 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
KCHIP1 ^¹, ², ³
KChIP1 ^³
MGC95 ^²
VABP ^², ³

Descriptions
A-type potassium channel modulatory protein 1 ^², ³
Kv channel interacting protein 1 ^²
Potassium channel-interacting protein 1 ^³
Vesicle APC-binding protein ^², ³
potassium channel interacting protein 1 ^²

External Ids
HGNC: 15521¹
Entrez Gene: 30820²
UniProtKB: Q9NZI2³
Ensembl: ENSG00000182132⁷

Search outside databases for aliases for KCNIP1 gene

Previous GC identifers: GC05P170167 GC05P170634 GC05P169911 GC05P169863

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KCNIP1:

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting

proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the

KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ

from each other in the N-terminus. They are integral subunit components of native Kv4 channel

complexes. They may regulate A-type currents, and hence neuronal excitability, in response to

changes in intracellular calcium. Alternative splicing results in multiple transcript variant

encoding different isoforms. [provided by RefSeq]

UniProtKB/Swiss-Prot: KCIP1_HUMAN, Q9NZI2

Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type

potassium channels. Probably modulates channels density, inactivation kinetics and rate of

recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates

KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell

surface

Gene Wiki entry for KCNIP1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the KCNIP1 gene

Entrez Gene cytogenetic band: 5q35.1 Ensembl cytogenetic band: 5q35.1 HGNC cytogenetic band: 5q35

KCNIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P169716: (about GC identifiers)

Start:	169,713,459 bp from pter
End:	170,096,214 bp from pter
Size:	382,756 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000005.8 NT_023133.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: KCIP1_HUMAN, Q9NZI2 (See protein sequence)

Recommended Name: Kv channel-interacting protein 1

Size: 227 amino acids; 26817 Da

Subunit: Component of heteromultimeric potassium channels. Interacts with KCND3 and the N-terminal

domain of KCND2. Probably part of a complex consisting of KCNIP1, KCNIP2 isoform 3 and KCND2. Can

self-associate to form homodimers and homotetramers. Interacts with KCNIP2 isoform 3 in a

calcium-dependent manner. Interacts with Naja atra venom CTX3

Subcellular location: Cell membrane; Peripheral membrane protein (By similarity)

PDB structures from and Proteopedia :

1S1E (3D)

2I2R (3D)

2NZ0 (3D)

Secondary accessions: Q5U822

Alternative splicing: 3 isoforms: Q9NZI2-1 Q9NZI2-2 Q9NZI2-3

REFSEQ proteins (3 alternative transcripts):

NP_001030009.1 NP_001030010.1 NP_055407.1

ENSEMBL proteins:

ENSP00000375071 ENSP00000329686 ENSP00000366577

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KCNIP1)
	Human Recombinant Proteins from Abnova (KCNIP1)

OriGene Purified Recombinant Human Protein: KCNIP1

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--

About this table

Antibodies for KCNIP1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for KCNIP1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (KCNIP1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (KCNIP1)
	Novus Biologicals Antibody for KCNIP1

Assays for KCNIP1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NZI2

ProtoNet protein and cluster: Q9NZI2

1 Blocks protein family: IPB001125 Recoverin family signature

UniProtKB/Swiss-Prot: KCIP1_HUMAN, Q9NZI2

Similarity: Belongs to the recoverin family

Similarity: Contains 4 EF-hand domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNIP1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNIP1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001034837

Applied Biosystems Silencer® siRNAs for KCNIP1

Sigma-Aldrich siRNA and siRNA Panels for KCNIP1

Sigma-Aldrich shRNA Panels and shRNA for KCNIP1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for KCNIP1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001034837
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001034837
untagged cDNA clones in CMV expression vector (see all 4): NM_001034837

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001034837

UniProtKB/Swiss-Prot: KCIP1_HUMAN, Q9NZI2

Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type

potassium channels. Probably modulates channels density, inactivation kinetics and rate of

recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates

KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell

surface

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005244	voltage-gated ion channel activity	IEA	--
GO:0005267	potassium channel activity	IEA	--
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	IPI	15358149
GO:0030955	potassium ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for KCNIP1

1 Interacting protein for KCNIP1 (Q9NZI2¹) via UniProtKB, MINT, and/or STRING
Interactant Interaction Details
GeneCard External ID(s)
KCND2 Q9NZV8¹ EBI-2120635, EBI-1646745
About this table
5 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0005513 detection of calcium ion TAS 10676964
GO:0006811 ion transport IEA --
GO:0006813 potassium ion transport IEA --
GO:0007165 signal transduction TAS 10676964
GO:0007268 synaptic transmission TAS 10676964
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for KCNIP1

Browse Small Molecules at Sigma-Aldrich

Compounds for KCNIP1 available from Tocris Bioscience

Compound	Action	CAS number
AM 92016 hydrochloride	KV channel blocker	[178894-81-0]
KN-93	CaM kinase II inhibitor. Also K+ channel blocker (KV)	[139298-40-1]
SG 209	K+ channel opener	[83440-03-3]
4-Aminopyridine	K+ channel blocker	[504-24-5]

About this table

2 Novoseek chemical compound relationships for KCNIP1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
potassium	38.87	1	14980206 (1)
calcium	15.85	2	14600268 (1), 18201103 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNIP1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNIP1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001034837

Sigma-Aldrich siRNA and siRNA Panels for KCNIP1

Sigma-Aldrich shRNA Panels and shRNA for KCNIP1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001034837 NM_001034838 NM_014592

REFSEQ mRNAs for KCNIP1 gene (3 alternative transcripts):

NM_001034837.1 NM_001034838.1 NM_014592.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001034837 NM_001034838 NM_014592

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001034837
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001034837
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_001034837

Additional cDNA sequence: AK124041.1

7 DOTS entries:

DT.40315513 DT.120848015 DT.101960252 DT.120848016 DT.120847999 DT.75143416 DT.97810830

24/33 AceView cDNA sequences (see all 33 ):

BX420376 CR602352 CA942614 NM_014592 CR602258 BM920920 AF199597 AI333844

CA942598 AL538404 BC050375 AY170821 AL567288 BX451738 BC035032 AI004002

BU790505 BX464072 BX461539 AK074390 CA942856 BE464646 AI422813 BI546102

highest scoring ESTs for KCNIP1:

AI422813 AF199597 AI004002 AI333844 AI498849 AK074390 AL567288 AY170821 BC035032 BC050375

Unigene Clusters for KCNIP1:

Kv channel interacting protein 1

Hs.484111 [show with all ESTs], Hs.689588 [show with all ESTs]

Unigene Representative Sequences: NM_001034837, AK124041

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for KCNIP1

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	·	3c	^	4	^	5a	·	5b	^	6	^	7	^	8	^	9a	·	9b	·	9c
SP1:											-								-
SP2:									-		-								-
SP3:									-		-
SP4:									-

About this scheme

ECgene alternative splicing isoforms for KCNIP1

3 Ensembl transcripts including schematic representations:

ENST00000390656 ENST00000328939 ENST00000377360

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KCNIP1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KCNIP1

¹ / ² / ³

3 probe-sets matching KCNIP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
90703_at²^{, 3}	U95-D	1	1.00	1.00	1.00	1.00	AI422813	1.00	1.00	1.00	1
221307_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_014592	0.60	1.00	0.82	1
221307_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks KCNIP1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTCTAACCAA

SOURCE GeneReport for Unigene clusters: Hs.484111 Hs.689588
UniProtKB/Swiss-Prot: KCIP1_HUMAN, Q9NZI2
Tissue specificity: Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also
expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also
expressed in lung, pancreas, leukocytes, prostate and thymus

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KCNIP1 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KCNIP1¹	--	Kv channel interacting protein 1	90.82(n) 93.37(a)	489125 XM_546243.2 XP_546243.2
chimpanzee (Pan troglodytes)	KCNIP1¹	--	Kv channel interacting protein 1	99.23(n) 100(a)	471735 XM_001150323.1 XP_001150323.1
cow (Bos taurus)	KCNIP1¹	--	Kv channel interacting protein 1	94.29(n) 98.15(a)	541458 NM_001013604.1 NP_001013622.1
rat (Rattus norvegicus)	Kcnip1¹	--	Kv channel-interacting protein 1	94.6(n) 99.54(a)	65023 NM_022929.1 NP_075218.1
mouse (Mus musculus)	Kcnip1^{1, 5}	11⁵	Kv channel-interacting protein 1^{1, 5}	91.67(n)¹ 99.54(a)¹	70357¹ NM_027398.2¹ NP_081674.2¹ AB075041⁵ AI842357⁵ (see all 20)

About this table Species with no ortholog for KCNIP1

ENSEMBL Gene Tree for KCNIP1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KCNIP1 gene

KCNIP4²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1990 NCBI SNPs in KCNIP1 are shown (see all 1990 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 854)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1363713^1,2	A,C,F,H,O	170095672(+)	`GGAAGT/GTCCCT`	3	--	ut3¹		9	EA EU WA	2336
	rs1363714^1,2	A,C,F,H	170096486(+)	`tctgcA/Gtgtaa`	3	--	ng3¹		11	NA EA MN EU WA	1122
	rs1055381^1,2	C,F,H,O	170095949(+)	`CATGAC/TATTGT`	3	--	ut3¹		17	EA MN NA EU WA	3014
	rs2112602^1,2	C,F,H,O	169861910(+)	`CTGCAT/CAGGTG`	3	--	int¹ ng5¹		5	EA NA	320
	rs6872337^1,2	A,C,F,H	170096502(+)	`CCCAAG/TAAGTT`	3	--	ng3¹		8	EU EA WA	838
--	rs6555900^1,2	A,C,F,H	169863822(+)	`GGCGGG/CCGCTC`	3	--	ut5¹ int¹		4	EU EA WA	402
	rs6555896^1,2	A,C,F,H	169712035(+)	`GAACAC/TGGGGT`	1	--	ng5¹		12	EA NA EU WA	1052
	rs12657389^1,2	C,F,H	169711794(+)	`TAACAC/TGGCAA`	1	--	ng5¹		7	EU EA WA NA	560
	rs13340390^1,2	F,H	169712796(+)	`TCCCCG/AGAGGC`	1	--	ng5¹		4	EU EA WA	414
	rs6894729^1,2	F,H	169713335(+)	`CCTGGC/TTTCAG`	1	--	ng5¹		4	EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for KCNIP1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604660

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/26 PubMed articles for KCNIP1 gene (see all 26 ):

Modulation of A-type potassium channels by a family of calcium sensors. (PubMed id 10676964)^{2, 3, 4} An W.F.... Rhodes K.J. (2000)
Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. (PubMed id 14980207)^{1, 3, 4} Scannevin R.H.... Rhodes K.J. (2004)
Different effects of the Ca(2+)-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2. (PubMed id 11423117)^{1, 3, 4} Nakamura T.Y....Coetzee W.A. (2001)
Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer. (PubMed id 17057713)^{3, 4} Pioletti M....Minor D.L. (2006)
Evidence showing an intermolecular interaction between KChIP proteins and Taiwan cobra cardiotoxins. (PubMed id 15184042)^{3, 4} Lin Y.-L.... Chang L.-S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Protein-protein interactions of KChIP proteins and Kv4.2. (PubMed id 15358149)^{3, 4} Lin Y.-L.... Chang L.S. (2004)
Differential modulation of Kv4 kinetics by KCHIP1 splice variants. (PubMed id 14572458)^{3, 4} Van Hoorick D.... Snyders D.J. (2003)
A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels. (PubMed id 12829703)^{3, 4} Shibata R.... Trimmer J.S. (2003)
Structure, alternative splicing, and expression of the human and mouse KCNIP gene family. (PubMed id 16112838)^{1, 3} Pruunsild P. and Timmusk T. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 30820	HGNC: 15521	AceView: KCNIP1	Ensembl:ENSG00000182132	euGenes: HUgn30820
ECgene: KCNIP1	H-InvDB: KCNIP1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KCNIP1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for KCNIP1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KCNIP1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KCNIP1		Antibodies for KCNIP1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KCNIP1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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	shRNA in GFP-retroviral vector

Tocris compounds for KCNIP1

	Drugs for KCNIP1
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

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KCNIP1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for KCNIP1

Summaries
for KCNIP1

Genomic Location
for KCNIP1

Proteins
for KCNIP1

Protein Domains/
Families
for KCNIP1

Gene Function
for KCNIP1

Pathways & Interactions
for KCNIP1

Drugs & Compounds
for KCNIP1

Transcripts
for KCNIP1

Expression
for KCNIP1

Orthologs
for KCNIP1

Paralogs
for KCNIP1

SNPs/Variants
for KCNIP1

Disorders & Mutations
for KCNIP1

Medical News
for KCNIP1

Publications
for KCNIP1

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Genome Databases showing KCNIP1

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Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KCNIP1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor KCNIP1

Summariesfor KCNIP1

Genomic Locationfor KCNIP1

Proteinsfor KCNIP1

Protein Domains/Familiesfor KCNIP1

Gene Functionfor KCNIP1

Pathways & Interactionsfor KCNIP1

Drugs & Compoundsfor KCNIP1

Transcriptsfor KCNIP1

Expression for KCNIP1

Orthologsfor KCNIP1

Paralogsfor KCNIP1

SNPs/Variantsfor KCNIP1

Disorders & Mutationsfor KCNIP1

Medical Newsfor KCNIP1

Publicationsfor KCNIP1

Search for KCNIP1

Genome Databases showing KCNIP1

Other Databases showing KCNIP1

Specialized Databases showing KCNIP1

Licensable Technologiesfor KCNIP1

Servicesfor KCNIP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KCNIP1

Summaries
for KCNIP1

Genomic Location
for KCNIP1

Proteins
for KCNIP1

Protein Domains/
Families
for KCNIP1

Gene Function
for KCNIP1

Pathways & Interactions
for KCNIP1

Drugs & Compounds
for KCNIP1

Transcripts
for KCNIP1

Expression
for KCNIP1

Orthologs
for KCNIP1

Paralogs
for KCNIP1

SNPs/Variants
for KCNIP1

Disorders & Mutations
for KCNIP1

Medical News
for KCNIP1

Publications
for KCNIP1

Licensable Technologies
for KCNIP1

Services
for KCNIP1