KCNH6 Gene
protein-coding GIFtS: 56
GCID: GC17P061600
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|
potassium voltage-gated channel, subfamily H (eag-related),...
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Aliases
for KCNH6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 61 2 | | ERG22 3 | | HERG21 2 | | HERG-21 | | Kv11.21 2 | | Erg21 | | Eag-Related Protein 22 3 | | Eag Related Protein 22 | | Ether-A-Go-Go-Related Gene Potassium Channel 22 3 | | Eag-Related Gene Member 22 | | Ether-A-Go-Go-Related Protein 22 3 | | Ether-A-Go-Go Related Gene Potassium Channel 22 | | Voltage-Gated Potassium Channel Subunit Kv11.22 3 | | Potassium Voltage-Gated Channel Subfamily H Member 62 | | ERG-22 3 | | HERG21 2 |
Export aliases for KCNH6 gene to outside databasesPrevious GC identifers: GC17P061251 GC17P064027 GC17P061941 GC17P062074 GC17P058954 GC17P056966 |
Summaries
for KCNH6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KCNH6:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from bothfunctional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heartrate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cellvolume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming(alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but thefull-length nature of only two transcript variants has been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KCNH6_HUMAN, Q9H252Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifyingcurrent (By similarity). Channel properties may be modulated by cAMP and subunit assembly
 summary
for KCNH6:Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.
Gene Wiki entry for KCNH6
|
Genomic Views
for KCNH6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNH6 gene promoter:
CREB RFX1 POU2F1 POU2F1a COMP1 NRSF form 1 NRSF form 2 GATA-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNH6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNH6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q23.3 Ensembl cytogenetic band: 17q23.3 HGNC cytogenetic band: 17q23.3KCNH6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P061600: view genomic region
(about GC identifiers)
Start:
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61,600,695 bp from pter |
End:
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61,626,338 bp from pter |
Size:
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25,644 bases |
Orientation:
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plus strand |
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Proteins
for KCNH6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNH6_HUMAN, Q9H252 (See
protein sequence)Recommended Name: Potassium voltage-gated channel subfamily H member 6 Size: 994 amino acids; 109925 Da
Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alphasubunits that can associate with modulating beta subunits. Heteromultimers with KCNH2/ERG1 and KCNH7/ERG3 (Bysimilarity)
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q9BRD7Alternative splicing: 3 isoforms: Q9H252-1 Q9H252-2 Q9H252-3 Explore the universe of human proteins at neXtProt for KCNH6: NX_Q9H252
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H252
KCNH6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_110406.1 NP_775115.1
ENSEMBL proteins: ENSP00000463830 ENSP00000464672 ENSP00000462417 ENSP00000318212 ENSP00000463533 ENSP00000396900 Reactome Protein details: Q9H252
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
KCNH6 for ontologies About GeneDecksing
KCNH6 Antibody Products:
Assay Products for KCNH6: |
Protein
Domains /
Families
for KCNH6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNH6 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q9H252ProtoNet protein and cluster: Q9H252 5/7 Blocks protein families (see all 7): IPB000014 PAS domain IPB000595 Cyclic nucleotide-binding domain IPB001610 PAC motif IPB003938 EAG/ELK/ERG potassium channel family signature IPB003950 ELK potassium channel family signature
UniProtKB/Swiss-Prot: KCNH6_HUMAN, Q9H252Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged aminoacids at every third positionSimilarity: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.2/KCNH6 sub-subfamilySimilarity: Contains 1 cyclic nucleotide-binding domainSimilarity: Contains 1 PAC (PAS-associated C-terminal) domainSimilarity: Contains 1 PAS (PER-ARNT-SIM) domain |
Function
for KCNH6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KCNH6_HUMAN, Q9H252Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifyingcurrent (By similarity). Channel properties may be modulated by cAMP and subunit assembly
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNH6 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005242 | inward rectifier potassium channel activity |
-- | -- | | GO:0005249 | voltage-gated potassium channel activity |
IEA | -- |
KCNH6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for KCNH6:
Animal Models:
Mouse knock-out Kcnh6tm1Lex for KCNH6
1 MGI phenotypic allele  for Kcnh6 (no phenotypes)
KCNH6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KCNH6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Potassium Channels | | | 2 | Potassium transporters: inward current | | | 3 | Dopamine-DARPP32 Feedback onto cAMP Pathway | | | 4 | Transmission across Chemical Synapses | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KCNH6
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KCNH6
3 
Reactome Pathways for KCNH6
KCNH6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNH6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/41 Interacting proteins for KCNH6 (ENSP000003182124) via UniProtKB, MINT, STRING, and/or I2D (see all 41)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0006813 | potassium ion transport |
-- | -- | | GO:0007165 | signal transduction |
IEA | -- | | GO:0007268 | synaptic transmission |
TAS | -- | | GO:0051291 | protein heterooligomerization |
-- | -- |
KCNH6 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNH6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KCNH6 for compounds About GeneDecksing
Compounds for KCNH6 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| AM 92016 hydrochloride | KV channel blocker | [178894-81-0] | | NS 1643 | hERG channel activator. Antiarrhythmic | [448895-37-2] | | Dofetilide | hERG channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | [115256-11-6] | | E-4031 dihydrochloride | hERG channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | [113559-13-0] | | 4-Aminopyridine | Non-selective KV channel blocker | [504-24-5] |
1 HMDB Compound for KCNH6 About this table
5 DrugBank Compounds for KCNH6 About this table
3 Novoseek chemical compound relationships for KCNH6 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ergosterol |
75.5 |
1 |
11353609 (1) |
| sterol |
69.6 |
2 |
15855491 (1), 16033255 (1) |
| squalene |
62.9 |
1 |
15328107 (1) |
Search CenterWatch for drugs/clinical trials and news about KCNH6
|
Transcripts
for KCNH6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNH6 gene (2 alternative transcripts): NM_030779.2 NM_173092.1 Unigene Cluster for KCNH6: Potassium voltage-gated channel, subfamily H (eag-related), member 6 Hs.591177 [show with all ESTs]Unigene Representative Sequence: NM_0307796 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000581784(uc002jaz.1) ENST00000580652(uc002jax.1) ENST00000583465
ENST00000314672 ENST00000583023(uc002jay.3 uc010wpl.2 uc010wpm.2)
ENST00000456941
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KCNH6 (NM_173092) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNH6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNH6 |
Additional cDNA sequence: AF311913.1 AK090969.1 AK091877.1 AK296498.1 AK298363.1 BC006334.2 4 DOTS entries: DT.92001686 DT.40246903 DT.91740938 DT.91853909 24/25 AceView cDNA sequences (see all 25): BU170580 NM_030779 NM_173092 AF311913 CD632739 CD632729 AX746709 BG395842 AA908657 BF685466 CD632731 AX747233 BM561167 CD632727 AK091877 BM461490 AK090969 BC006334 CD632735 CD632733 H96171 BE465143 BE672839 CD632737
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for KCNH6 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KCNH6
|
Expression
for KCNH6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNH6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAGGACAGT
About this image
See KCNH6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCNH6
SOURCE GeneReport for Unigene cluster: Hs.591177
UniProtKB/Swiss-Prot: KCNH6_HUMAN, Q9H252Tissue specificity: Expressed in prolactin-secreting adenomas
SABiosciences Expression via Pathway-Focused PCR Array including KCNH6:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNH6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNH6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNH6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNH6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNH6 |
Orthologs
for KCNH6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNH6 gene from 5/19 species (see all 19) About this table
ENSEMBL Gene Tree for KCNH6 (if available)
TreeFam Gene Tree for KCNH6 (if available) |
Paralogs
for KCNH6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNH6 gene
- KCNH32 KCNH52 HCN32 HCN42 HCN22 KCNH42 CNGA22 CNGA12
- HCN12 KCNH72 KCNH22 CNGB12 CNGA42 CNGA32 CNGB32 KCNH12
- KCNH82
7 SIMAP similar genes for KCNH6 using alignment to 3 protein entries: KCNH6_HUMAN (see all proteins):KCNH2 KCNH8 KCNH5 KCNH1 KCNH7 KCNH4
KCNH3
KCNH6 for paralogs About GeneDecksing
|
Genomic Variants
for KCNH6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNH6 (61600695 - 61626338 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KCNH6: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNH6 |
|
Disorders
/ Diseases
for KCNH6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNH6 for disorders About GeneDecksing
OMIM gene information: 608168
OMIM disorders: --
12  diseases for KCNH6: About MalaCardsacute lymphoblastic leukemia chronic lymphocytic leukemia lymphoblastic leukemia lymphocytic leukemia
neuronitis leukemia seizures neuropathy
prostate cancer adenoma prostatitis schizophrenia
Human Genome Epidemiology (HuGE) Navigator: KCNH6 (1 document)
Export disorders for KCNH6 gene to outside databases
|
Publications
for KCNH6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNH6 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with KCNH6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- HERG K(+) currents in human prolactin-secreting adenoma cells. (PubMed id 12634931)1, 2, 9 Bauer C.K.... Schwarz J.R. (2003)
- International Union of Pharmacology. LIII. Nomenclatu re and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)1, 3 Gutman G.A....Wang X. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1 Kenny E.E....Peter I. (2012)
- Single nucleotide polymorphisms of matrix metalloprot einase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study E piLymph. (PubMed id 21048031)1 Casabonne D....de Sanjose S. (2010)
- No association between EGR gene family polymorphisms and schizophrenia in the Chinese population. (PubMed id 20144677)1 Liu B.C....He G. (2010)
- Ibutilide--recent molecular insights and accumulating evidence for use in atrial flutter and fibrillation. (PubMed id 15926871)7 Doggrell S.A. and Hancox J.C. (2005)
- Blockade of HERG cardiac K+ current by antifungal drug miconazole. (PubMed id 15778703)7 Kikuchi K....Nakashima Y. (2005)
- Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin. (PubMed id 15098086)7 Thomas D....Karle C.A. (2004)
|
External Searches for KCNH6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNH6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNH6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNH6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNH6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KCNH6 gene:
Search GeneIP for patents involving KCNH6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNH6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KCNH6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNH6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNH6 | | | OriGene Protein Over-expression Lysate for KCNH6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KCNH6 | | OriGene 3'-UTR Clone for KCNH6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNH6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KCNH6 | | OriGene Custom Protein Services for KCNH6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNH6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNH6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNH6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNH6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNH6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNH6 |
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| | | | Tocris compounds for KCNH6 |
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 | | | KCNH6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNH6 |
|  |  |  | | | | Search ThermoFisher Antibodies for KCNH6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNH6 |
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