V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

KCNH5 Gene

protein-coding GIFtS: 57

GC14M062243

potassium voltage-gated channel, subfamily H (eag-related), member 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EAG2 ^², ³
H-EAG2 ^¹, ²
Kv10.2 ^¹, ²
eag2 ^¹
hEAG2 ^³

Descriptions
Ether-a-go-go potassium channel 2 ^³
Voltage-gated potassium channel subunit Kv10.2 ^³
ether-a-go-go-related potassium channel 2 ^²
potassium channel HEAG2 ^²
potassium voltage-gated channel, subfamily H (eag-related), member 5 ^²
potassium voltage-gated channel, subfamily H, member 5 ^²
voltage-gated potassium channel EAG2 ^²

External Ids
HGNC: 6254¹
Entrez Gene: 27133²
UniProtKB: Q8NCM2³
Ensembl: ENSG00000140015⁷

Search outside databases for aliases for KCNH5 gene

Previous GC identifers: GC14M060501 GC14M056967 GC14M061163

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KCNH5:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion

channels from both functional and structural standpoints. Their diverse functions include

regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability,

epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a

member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha)

subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. This gene is not

expressed in differentiating myoblasts. Alternative splicing results in three transcript variants

encoding distinct isoforms. [provided by RefSeq]

UniProtKB/Swiss-Prot: KCNH5_HUMAN, Q8NCM2

Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a

non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and

subunit assembly

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the KCNH5 gene

Entrez Gene cytogenetic band: 14q23.1 Ensembl cytogenetic band: 14q23.2 HGNC cytogenetic band: 14q23.1

KCNH5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M062243: (about GC identifiers)

Start:	62,243,052 bp from pter
End:	62,638,337 bp from pter
Size:	395,286 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: KCNH5_HUMAN, Q8NCM2 (See protein sequence)

Recommended Name: Potassium voltage-gated channel subfamily H member 5

Size: 988 amino acids; 111907 Da

Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of

pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with

KCNH1/EAG (Probable)

Subcellular location: Membrane; Multi-pass membrane protein

Sequence caution: Sequence=BAC11016.1; Type=Erroneous termination; Positions=436; Note=Translated

as Gly;

Alternative splicing: 3 isoforms: Q8NCM2-1 Q8NCM2-2 Q8NCM2-3 (Experimental confirmation may be lacking for some isoforms)

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_647479.2 NP_758963.1 NP_758964.1

ENSEMBL proteins:

ENSP00000378419 ENSP00000378415 ENSP00000321427

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KCNH5)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for KCNH5:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of KCNH5
	Sigma-Aldrich Antibodies for KCNH5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (KCNH5), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibodies for KCNH5

Assays for KCNH5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8NCM2

ProtoNet protein and cluster: Q8NCM2

5/7 Blocks protein families (see all 7 ):

IPB000014 PAS domain

IPB000595 Cyclic nucleotide-binding domain

IPB001610 PAC motif

IPB003938 EAG/ELK/ERG potassium channel family signature

IPB003949 EAG potassium channel signature

UniProtKB/Swiss-Prot: KCNH5_HUMAN, Q8NCM2

Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of

positively charged amino acids at every third position

Similarity: Belongs to the potassium channel family. H (Eag) subfamily

Similarity: Contains 1 cyclic nucleotide-binding domain

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNH5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNH5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_172375

Applied Biosystems Silencer® siRNAs for KCNH5

Sigma-Aldrich siRNA and siRNA Panels for KCNH5

Sigma-Aldrich shRNA Panels and shRNA for KCNH5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_139318
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_139318
untagged cDNA clones in CMV expression vector (see all 5): NM_139318

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_139318

UniProtKB/Swiss-Prot: KCNH5_HUMAN, Q8NCM2

Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a

non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and

subunit assembly

Genatlas biochemistry entry for KCNH5:

potassium voltage-gated channel, subfamily H (eag-related), member 5

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Kcnh5):

behavior/neurological

hearing/vestibular/ear

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000155	two-component sensor activity	IEA	--
GO:0005244	voltage-gated ion channel activity	IEA	--
GO:0005249	voltage-gated potassium channel activity	IEA	--
GO:0005516	calmodulin binding	IEA	--
GO:0030955	potassium ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000160	two-component signal transduction system (phosphorelay)	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0006811	ion transport	IEA	--
GO:0006813	potassium ion transport	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for KCNH5 available from Tocris Bioscience

Compound	Action	CAS number
AM 92016 hydrochloride	KV channel blocker	[178894-81-0]
KN-93	CaM kinase II inhibitor. Also K+ channel blocker (KV)	[139298-40-1]
SG 209	K+ channel opener	[83440-03-3]
4-Aminopyridine	K+ channel blocker	[504-24-5]

About this table

1 Novoseek chemical compound relationship for KCNH5 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
potassium	36.08	1	11943152 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNH5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNH5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_172375

Sigma-Aldrich siRNA and siRNA Panels for KCNH5

Sigma-Aldrich shRNA Panels and shRNA for KCNH5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_139318 NM_172375 NM_172376

REFSEQ mRNAs for KCNH5 gene (3 alternative transcripts):

NM_139318.3 NM_172375.1 NM_172376.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_139318 NM_172375 NM_172376

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_139318
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_139318
                                 untagged cDNA clones in CMV expression vector (see all 5): NM_139318

Additional cDNA sequence:

AF418206.1 AF472412.1 AF493798.1 BC043409.2 BC073979.1

4 DOTS entries:

DT.100018940 DT.100018941 DT.97819289 DT.100741448

19 AceView cDNA sequences:

AF493798 NM_172375 BC073979 NM_172376 F05455 AF418206 Z38438 NM_139318

AW628656 F01716 AF472412 CD636893 BC043409 F05456 BX281706 U69185

AK074484 CD636891 BQ439615

highest scoring ESTs for KCNH5:

AF418206 AF472412 AF493798 BC043409 BQ439615 BX281706 U69185 AK074484 AW628656 BC073979

Unigene Cluster for KCNH5:

Potassium voltage-gated channel, subfamily H (eag-related), member 5

Hs.27043 [show with all ESTs]

Unigene Representative Sequence: BC073979

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for KCNH5

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13a	·	13b
SP1:					-		-														-
SP2:																					-								-
SP3:																					-						-		-
SP4:					-		-

About this scheme

ECgene alternative splicing isoforms for KCNH5

3 Ensembl transcripts including schematic representations:

ENST00000394968 ENST00000394964 ENST00000322893

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KCNH5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KCNH5

¹ / ² / ³

5 probe-sets matching KCNH5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
47008_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	U69185	0.80	1.00	0.91	1
242502_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AW628656	0.60	1.00	0.82	1
242502_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1555074_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1555304_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCAGGATATT

SOURCE GeneReport for Unigene cluster: Hs.27043
UniProtKB/Swiss-Prot: KCNH5_HUMAN, Q8NCM2
Tissue specificity: Detected in brain, skeletal muscle, heart, placenta, lung and liver, and at low
levels in kidney

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KCNH5 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KCNH5¹	--	potassium voltage-gated channel, subfamily H (eag-related), more	93.86(n) 99.09(a)	490724 XM_547846.2 XP_547846.2
chimpanzee (Pan troglodytes)	KCNH5¹	--	potassium voltage-gated channel, subfamily H (eag-related), more	99.59(n) 99.8(a)	467476 XM_522873.2 XP_522873.2
cow (Bos taurus)	KCNH5¹	--	potassium voltage-gated channel, subfamily H (eag-related), more	93.72(n) 99.09(a)	537813 XM_864922.2 XP_870015.1
rat (Rattus norvegicus)	Kcnh5¹	--	potassium voltage-gated channel, subfamily H (eag-related), more	91.4(n) 98.28(a)	171146 NM_133610.1 NP_598294.1
mouse (Mus musculus)	Kcnh5^{1, 5}	12⁵	potassium voltage-gated channel, subfamily H (eag-related), more^{1, 5}	91.33(n)¹ 97.98(a)¹	238271¹ NM_172805.2¹ NP_766393.1¹ AF309565⁵ AK032438⁵ (see all 6)

About this table Species with no ortholog for KCNH5

ENSEMBL Gene Tree for KCNH5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KCNH5 gene

KCNH1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1932 NCBI SNPs in KCNH5 are shown (see all 1932 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 670)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7161127^1,2	A,C,F,H	62244369(+)	`GTTTTC/TCTTAG`	2	R/R	syn¹ ut3¹		8		NA EU EA WA	640
	rs11158448^1,2	A,C,F,H	62248823(+)	`TCACTC/TCCACA`	3	--	int¹ ut3¹		11		NA EU EA WA	972
	rs4902176^1,2	A,C,F,H	62244713(+)	`GGAGGC/TTCCAT`	2	A/T	mis¹ ut3¹ ese³		12		NA EU EA WA	1050
	rs11158447^1,2	A,C,F,H	62248747(+)	`TTATTA/TTACTT`	3	--	int¹ ut3¹		4		EU EA WA	410
	rs12435381^1,2	A,C,F,H	62249086(+)	`GACTCC/TGTGAA`	3	--	ut3¹ int¹		11		NA EU EA WA	978
	rs7141353^1,2	A,C,F,H	62248388(+)	`TGGACA/GTGACT`	3	--	int¹ ng5¹		7		NA EU EA WA	560
	rs11158473^1,2	A,C,F,H	62639050(+)	`TTACAA/GCATAA`	1	--	ng3¹		11		EU EA WA NA	928
	rs17177422^1,2	C,F,H	62638881(+)	`GTTGGA/CGTGTC`	1	--	ng3¹		7		NA EU EA WA	550
	rs1956672^1,2	A,C	62582884(-)	`CCTGCC/TCCACC`	3	--	int¹ ng3¹		0	--	--	--	--
--	rs10132985^1,2	A,C	62583259(+)	`CCTCTC/TTTCTC`	3	--	int¹ ng3¹ tfbs³ trp³		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for KCNH5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605716

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/14 PubMed articles for KCNH5 gene (see all 14 ):

Functional distinction of human EAG1 and EAG2 potassium channels. (PubMed id 11943152)^{1, 3, 4} Schoenherr R.... Heinemann S.H. (2002)
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)^{2, 3} Gutman G.A....Wang X. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Molecular identification and characterisation of the human eag2 potassium channel. (PubMed id 12135768)^{3, 4} Ju M. and Wray D. (2002)
Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion. (PubMed id 9738473)^{2, 3} Occhiodoro T.... Fischer-Lougheed J. (1998)
Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells. (PubMed id 18655026)³ Tan F....Peng X. (2008)
DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients. (PubMed id 18349282)³ Feng Q....Vesselle H. (2008)
Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. (PubMed id 16303743)³ Otsuki T....Isogai T. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 27133	HGNC: 6254	AceView: KCNH5	Ensembl:ENSG00000140015	euGenes: HUgn27133
ECgene: KCNH5	H-InvDB: KCNH5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KCNH5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KCNH5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KCNH5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KCNH5		Antibodies for KCNH5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KCNH5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Chimera RNAi (KCNH5)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (KCNH5)
	Antibodies (KCNH5)

Search OriGene for KCNH5

Tocris compounds for KCNH5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for KCNH5

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
KCNH5 Gene at Home site.
Version 2.41.1
server4.xennexinc.com

KCNH5 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for KCNH5

Summaries
for KCNH5

Genomic Location
for KCNH5

Proteins
for KCNH5

Protein Domains/
Families
for KCNH5

Gene Function
for KCNH5

Pathways & Interactions
for KCNH5

Drugs & Compounds
for KCNH5

Transcripts
for KCNH5

Expression
for KCNH5

Orthologs
for KCNH5

Paralogs
for KCNH5

SNPs/Variants
for KCNH5

Disorders & Mutations
for KCNH5

Medical News
for KCNH5

Publications
for KCNH5

Search for KCNH5

Genome Databases showing KCNH5

Other Databases showing KCNH5

Specialized Databases showing KCNH5

Licensable Technologies
for KCNH5

Services
for KCNH5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KCNH5 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor KCNH5

Summariesfor KCNH5

Genomic Locationfor KCNH5

Proteinsfor KCNH5

Protein Domains/Familiesfor KCNH5

Gene Functionfor KCNH5

Pathways & Interactionsfor KCNH5

Drugs & Compoundsfor KCNH5

Transcriptsfor KCNH5

Expression for KCNH5

Orthologsfor KCNH5

Paralogsfor KCNH5

SNPs/Variantsfor KCNH5

Disorders & Mutationsfor KCNH5

Medical Newsfor KCNH5

Publicationsfor KCNH5

Search for KCNH5

Genome Databases showing KCNH5

Other Databases showing KCNH5

Specialized Databases showing KCNH5

Licensable Technologiesfor KCNH5

Servicesfor KCNH5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KCNH5

Summaries
for KCNH5

Genomic Location
for KCNH5

Proteins
for KCNH5

Protein Domains/
Families
for KCNH5

Gene Function
for KCNH5

Pathways & Interactions
for KCNH5

Drugs & Compounds
for KCNH5

Transcripts
for KCNH5

Expression
for KCNH5

Orthologs
for KCNH5

Paralogs
for KCNH5

SNPs/Variants
for KCNH5

Disorders & Mutations
for KCNH5

Medical News
for KCNH5

Publications
for KCNH5

Licensable Technologies
for KCNH5

Services
for KCNH5