Aliases for KCNG4 Gene
Aliases for KCNG4 Gene
- Potassium Voltage-Gated Channel Modifier Subfamily G Member 4 2 3 5
- Potassium Voltage-Gated Channel, Subfamily G, Member 4 2 3
- Voltage-Gated Potassium Channel Subunit Kv6.4 3 4
- Potassium Channel, Voltage Gated Modifier Subfamily G, Member 4 3
- Potassium Voltage-Gated Channel Subfamily G Member 4 3
- Voltage-Gated Potassium Channel Kv6.3 3
- KV6.3 3
- KV6.4 3
- KCNG3 4
External Ids for KCNG4 Gene
- HGNC: 19697
- Entrez Gene: 93107
- Ensembl: ENSG00000168418
- OMIM: 607603
- UniProtKB: Q8TDN1
Previous GeneCards Identifiers for KCNG4 Gene
- GC16M085222
- GC16M083994
- GC16M084035
- GC16M082813
- GC16M070009
Summaries for KCNG4 Gene
-
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNG4 Gene
KCNG4 (Potassium Voltage-Gated Channel Modifier Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are Potassium Channels and Transmission across Chemical Synapses. GO annotations related to this gene include ion channel activity and delayed rectifier potassium channel activity. An important paralog of this gene is KCNG1.
UniProtKB/Swiss-Prot for KCNG4 Gene
-
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:19074135).
-
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNG4 Gene
Genomics for KCNG4 Gene
Regulatory Elements for KCNG4 Gene
Enhancers for KCNG4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around KCNG4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for KCNG4 Gene
- Chromosome:
- 16
- Start:
- 84,218,667 bp from pter
- End:
- 84,239,750 bp from pter
- Size:
- 21,084 bases
- Orientation:
- Minus strand
Genomic View for KCNG4 Gene
Genes around KCNG4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.1 by Ensembl
- 16q24.1 by Entrez Gene
- 16q24.1 by HGNC
KCNG4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KCNG4 Gene
Proteins for KCNG4 Gene
-
Protein details for KCNG4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TDN1-KCNG4_HUMAN
- Recommended name:
- Potassium voltage-gated channel subfamily G member 4
- Protein Accession:
- Q8TDN1
- Q96H24
Protein attributes for KCNG4 Gene
- Size:
- 519 amino acids
- Molecular mass:
- 58979 Da
- Quaternary structure:
-
- Heterotetramer with KCNB1 (PubMed:19074135).
Post-translational modifications for KCNG4 Gene
Other Protein References for KCNG4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for KCNG4
- Invitrogen Antibodies for KCNG4
- antibodies-online Antibodies for KCNG4: See all 25
- GeneTex KCNG4 antibody for KCNG4
Protein Products
-
OriGene Purified Proteins for KCNG4
- Search Origene for MassSpec and Protein Over-expression Lysates for KCNG4
- Origene Custom Protein Services for KCNG4
- Search GeneTex for Proteins for KCNG4
No data available for DME Specific Peptides for KCNG4 Gene
Domains & Families for KCNG4 Gene
Gene Families for KCNG4 Gene
- HGNC:
- IUPHAR :
Protein Domains for KCNG4 Gene
Suggested Antigen Peptide Sequences for KCNG4 Gene
Graphical View of Domain Structure for InterPro Entry
Q8TDN1UniProtKB/Swiss-Prot:
KCNG4_HUMAN :- The transmembrane segment S4 functions as voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.
- Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.4/KCNG4 sub-subfamily.
- Domain:
-
- The transmembrane segment S4 functions as voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.
- Family:
-
- Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.4/KCNG4 sub-subfamily.
Function for KCNG4 Gene
Molecular function for KCNG4 Gene
- UniProtKB/Swiss-Prot Function:
- Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:19074135).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005244 | voltage-gated ion channel activity | IEA | -- |
| GO:0005249 | voltage-gated potassium channel activity | IEA | -- |
| GO:0005251 | delayed rectifier potassium channel activity | IDA | 19074135 |
| GO:0005267 | potassium channel activity | IEA | -- |
| GO:0044325 | ion channel binding | IPI | 19074135 |
Phenotypes for KCNG4 Gene
- GenomeRNAi human phenotypes for KCNG4:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Resistant to vaccinia virus (VACV-A4L) infection
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Increased shRNA abundance (Z-score > 2)
- Increased HPV16-GFP infection
- Decreased shRNA abundance (Z-score < -2)
Animal Model Products
-
Taconic Biosciences Mouse Models for KCNG4
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNG4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for KCNG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for KCNG4 gene
- Search ViGene Biosciences for KCNG4
CRISPR Products
-
OriGene CRISPR knockouts for KCNG4
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNG4
- GenScript: Design CRISPR guide RNA sequences for KCNG4
miRNA for KCNG4 Gene
- miRTarBase miRNAs that target KCNG4
miRNA Products
- Search ViGene Biosciences for KCNG4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for KCNG4
- Browse OriGene Inhibitory RNA Products For KCNG4
-
ViGene Biosciences ready-to-package AAV shRNAs for KCNG4 gene
Clone Products
- Sino Biological Human cDNA Clone for KCNG4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for KCNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for KCNG4
-
ViGene Biosciences adenoviral particle packaged cDNA for KCNG4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for KCNG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for KCNG4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KCNG4 Gene
Localization for KCNG4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNG4 Gene
- Cell membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Colocalizes with KCNB1 at the plasma membrane. Remains intracellular in the absence of KCNB1 (PubMed:19074135). {ECO:0000269 PubMed:19074135}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0008076 | colocalizes_with voltage-gated potassium channel complex | IEA,IDA | 19074135 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for KCNG4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Potassium Channels | ||
| 2 | Dopamine-DARPP32 Feedback onto cAMP Pathway | ||
| 3 | Transmission across Chemical Synapses |
.62
|
|
Pathways by source for KCNG4 Gene
3 Reactome pathways for KCNG4 Gene
1 Qiagen pathway for KCNG4 Gene
Interacting Proteins for KCNG4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006813 | potassium ion transport | IEA | -- |
| GO:0034765 | regulation of ion transmembrane transport | IEA | -- |
| GO:0051260 | protein homooligomerization | IEA | -- |
No data available for SIGNOR curated interactions for KCNG4 Gene
Drugs & Compounds for KCNG4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| 4-Aminopyridine | Approved | Pharma | Pore Blocker | potassium channel-blocking agent, Non-selective KV channel blocker | 69 | |
| E-4031 dihydrochloride | Pharma | KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | 0 | |||
| Linopirdine dihydrochloride | Pharma | KV7 (KCNQ) channel blocker | 0 | |||
| XE 991 dihydrochloride | Pharma | Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| HMR 1556 |
|
223749-46-0 |
|
|
(5) Tocris Compounds for KCNG4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-Aminopyridine | Non-selective KV channel blocker | 504-24-5 |
| E-4031 dihydrochloride | KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | 113559-13-0 |
| HMR 1556 | Potent and selective Iks channel blocker | 223749-46-0 |
| Linopirdine dihydrochloride | KV7 (KCNQ) channel blocker | 113168-57-3 |
| XE 991 dihydrochloride | Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents | 122955-13-9 |
Transcripts for KCNG4 Gene
mRNA/cDNA for KCNG4 Gene
- (2) REFSEQ mRNAs :
- (9) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for KCNG4
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNG4
- GenScript: Design CRISPR guide RNA sequences for KCNG4
miRNA Products
- Search ViGene Biosciences for KCNG4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for KCNG4
- Browse OriGene Inhibitory RNA Products For KCNG4
-
ViGene Biosciences ready-to-package AAV shRNAs for KCNG4 gene
Clone Products
- Sino Biological Human cDNA Clone for KCNG4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for KCNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for KCNG4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
mRNA differential expression in normal tissues according to GTEx for KCNG4 Gene
This gene is overexpressed in Brain - Substantia nigra (x6.5), Brain - Amygdala (x5.4), Brain - Hippocampus (x4.9), Brain - Hypothalamus (x4.8), and Brain - Putamen (basal ganglia) (x4.1).
NURSA nuclear receptor signaling pathways regulating expression of KCNG4 Gene:
KCNG4SOURCE GeneReport for Unigene cluster for KCNG4 Gene:
Hs.335877mRNA Expression by UniProt/SwissProt for KCNG4 Gene:
Q8TDN1-KCNG4_HUMAN
Tissue specificity:
Highly expressed in brain, and at lower levels in liver, small intestine and colon.
Evidence on tissue expression from TISSUES for KCNG4 Gene
- Muscle(4.3)
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for KCNG4
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNG4 Gene
Orthologs for KCNG4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KCNG4 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | KCNG4 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | KCNG4 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Kcng4 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Kcng4 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KCNG4 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | KCNG4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CKV6.3 35 |
|
OneToOne | |
| KCNG4 34 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | KCNG4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kcng4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | kcng4a 34 35 |
|
||
| KCNG4 (1 of 2) 35 |
|
OneToMany |
- Species where no ortholog for KCNG4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KCNG4 Gene
Paralogs for KCNG4 Gene
(16) SIMAP similar genes for KCNG4 Gene using alignment to 3 proteins:
Variants for KCNG4 Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000012795 | -- | 84,238,881(+) | AAAAA(A/C)AAAAA | intron-variant | |
| rs1000016728 | -- | 84,226,772(+) | TACTT(C/G)GCGGG | intron-variant | |
| rs1000106886 | -- | 84,228,495(+) | TTTCT(C/T)TCGGC | intron-variant | |
| rs1000118187 | -- | 84,228,591(+) | CTCCT(C/T)CCCAG | intron-variant | |
| rs1000206938 | -- | 84,240,863(+) | TGGCT(A/T)CTGAA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2672151 | CNV | deletion | 23128226 |
| esv2761930 | CNV | gain | 21179565 |
| esv3639412 | CNV | loss | 21293372 |
| esv3639413 | CNV | loss | 21293372 |
| esv3639414 | CNV | loss | 21293372 |
| esv3639415 | CNV | loss | 21293372 |
| nsv1059227 | CNV | loss | 25217958 |
| nsv1065790 | CNV | loss | 25217958 |
| nsv1111143 | CNV | tandem duplication | 24896259 |
| nsv483044 | CNV | gain | 15286789 |
| nsv833309 | CNV | loss | 17160897 |
| nsv833310 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
89.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
18.17;
98.48% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KCNG4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KCNG4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNG4 Gene
Disorders for KCNG4 Gene
Relevant External Links for KCNG4
No disorders were found for KCNG4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KCNG4 Gene
Publications for KCNG4 Gene
- Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome. (PMID: 12060745) Ottschytsch N. … Snyders D.J. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4. (PMID: 19074135) Mederos Y Schnitzler M. … Preisig-Muller R. (J. Biol. Chem. 2009) 3 4 64
- International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. (PMID: 16382104) Gutman G.A. … Wang X. (Pharmacol. Rev. 2005) 2 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
Products for KCNG4 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for KCNG4
- Search Origene for MassSpec and Protein Over-expression Lysates for KCNG4
- Origene Custom Protein Services for KCNG4
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for KCNG4
- Browse OriGene Inhibitory RNA Products For KCNG4
- OriGene qPCR primer pairs for KCNG4
- OriGene CRISPR knockouts for KCNG4
- OriGene ORF clones in human for KCNG4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For KCNG4
- GenScript: Next-day shipping cDNA ORF clone for KCNG4 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for KCNG4
- GenScript Custom Assay Services for KCNG4
- GenScript Custom overexpressing Cell Line Services for KCNG4
- GenScript: Design CRISPR guide RNA sequences for KCNG4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for KCNG4
- Sino Biological Human cDNA Clone for KCNG4
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for KCNG4
- Novus Biologicals proteins and lysates for KCNG4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for KCNG4
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for KCNG4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- GeneTex KCNG4 antibody for KCNG4
- Search GeneTex for Proteins for KCNG4
- ViGene Biosciences adenoviral particle packaged cDNA for KCNG4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for KCNG4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KCNG4 gene
- Search ViGene Biosciences for KCNG4
- Horizon Cell Lines for KCNG4
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNG4
- VectorBuilder custom plasmid, inducible vectors for KCNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNG4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for KCNG4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer