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KCNG2 Gene

protein-coding   GIFtS: 51
GCID: GC18P077677

Potassium Voltage-Gated Channel, Subfamily G, Member 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Potassium Voltage-Gated Channel, Subfamily G, Member 21 2
Cardiac Potassium Channel Subunit2 3
Voltage-Gated Potassium Channel Subunit Kv6.22 3
KCNF22 3
KV6.22
Potassium Voltage-Gated Channel Subfamily G Member 22

External Ids:    HGNC: 62491   Entrez Gene: 262512   Ensembl: ENSG000001783427   OMIM: 6056965   UniProtKB: Q9UJ963   

Export aliases for KCNG2 gene to outside databases

Previous GC identifers: GC18P077138 GC18P077358 GC18P075722 GC18P075724 GC18P074246


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KCNG2 Gene:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both
functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart
rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and
cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a
gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit
may contribute to cardiac action potential repolarization. (provided by RefSeq, Jul 2008)

GeneCards Summary for KCNG2 Gene:
KCNG2 (potassium voltage-gated channel, subfamily G, member 2) is a protein-coding gene. GO annotations related to this gene include delayed rectifier potassium channel activity. An important paralog of this gene is KCNF1.

UniProtKB/Swiss-Prot: KCNG2_HUMAN, Q9UJ96
Function: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal
activation to more negative values

summary for KCNG2 Gene:
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.

Gene Wiki entry for KCNG2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NC_018929.2  NT_010966.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCNG2 gene promoter:
         AhR   AP-2gamma   GATA-1   Arnt   GATA-2   Max   POU2F1a   ATF   c-Myc   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): KCNG2 promoter sequence
   Search Chromatin IP Primers for KCNG2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCNG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q23   Ensembl cytogenetic band:  18q23   HGNC cytogenetic band: 18q23

KCNG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNG2 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P077677:  view genomic region     (about GC identifiers)

Start:
77,623,668 bp from pter      End:
77,660,184 bp from pter
Size:
36,517 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KCNG2_HUMAN, Q9UJ96 (See protein sequence)
Recommended Name: Potassium voltage-gated channel subfamily G member 2  
Size: 466 amino acids; 51240 Da
Subunit: Heterodimer with KCNB1. Does not form homomultimers
Miscellaneous: Heterodimers with KCNB1 are highly sensitive to inhibition by tetraethylammonium (TEA) and
propafenone

Explore the universe of human proteins at neXtProt for KCNG2: NX_Q9UJ96

Explore proteomics data for KCNG2 at MOPED


See KCNG2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_036415.1  
ENSEMBL proteins: 
 ENSP00000315654  
Reactome Protein details: Q9UJ96

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
KCN: Potassium channels
Kv: Voltage-gated ion channels / Potassium channels

IUPHAR Guide to PHARMACOLOGY protein family classification: Kv6.2
Voltage-gated potassium channels

Selected InterPro protein domains (see all 9):
 IPR005821 Ion_trans_dom
 IPR000210 BTB/POZ-like
 IPR011333 BTB/POZ_fold
 IPR027359 Channel_four-helix_dom
 IPR028325 VG_K_chnl

Graphical View of Domain Structure for InterPro Entry Q9UJ96

ProtoNet protein and cluster: Q9UJ96

3 Blocks protein domains:
IPB000210 BTB/POZ domain
IPB003091 Potassium channel signature
IPB003969 Kv6 potassium channel alpha subunit signature


UniProtKB/Swiss-Prot: KCNG2_HUMAN, Q9UJ96
Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino
acids at every third position
Similarity: Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.2/KCNG2 sub-subfamily


Find genes that share domains with KCNG2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: KCNG2_HUMAN, Q9UJ96
Function: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal
activation to more negative values

     Genatlas biochemistry entry for KCNG2:
potassium voltage-gated channel,subfamily G,member 2,rat Kv6.2 homolog,preferentially expressed in myocard

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005216ion channel activity ----
GO:0005251delayed rectifier potassium channel activity TAS10551266
GO:0005515protein binding ----
     
Find genes that share ontologies with KCNG2           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for KCNG2:
 Increased circadian period len 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCNG2
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
KCNG2_HUMAN, Q9UJ96: Membrane; Multi-pass membrane protein
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane4

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0008076voltage-gated potassium channel complex IEA--
GO:0016020membrane ----
GO:0070062extracellular vesicular exosome IDA19056867

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for KCNG2 About    
See pathways by source

SuperPathContained pathways About
1Integration of energy metabolism
Integration of energy metabolism0.75
Regulation of Insulin Secretion by Glucagon-like Peptide-10.56
Regulation of Insulin Secretion0.75
2Potassium Channels
Potassium Channels0.43
Voltage gated Potassium channels0.43
3Transmission across Chemical Synapses
Neuronal System0.68
4Metabolism
Metabolism0.38
5Dopamine-DARPP32 Feedback onto cAMP Pathway
Dopamine-DARPP32 Feedback onto cAMP Pathway


Find genes that share SuperPaths with KCNG2           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for KCNG2
    Dopamine-DARPP32 Feedback onto cAMP Pathway

2 Reactome Pathways for KCNG2
    Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Voltage gated Potassium channels


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCNG2
Interactions:

    Search GeneGlobe Interaction Network for KCNG2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for KCNG2 (Q9UJ963 ENSP000003156544) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
InteractantInteraction Details
GeneCardExternal ID(s)
KCNB1Q147213, ENSP000003608064I2D: score=2 STRING: ENSP00000360806
KCNA10ENSP000003587864STRING: ENSP00000358786
KCNA2ENSP000003145204STRING: ENSP00000314520
KCNA3ENSP000003587844STRING: ENSP00000358784
KCNA4ENSP000003285114STRING: ENSP00000328511
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Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006112energy reserve metabolic process TAS--
GO:0006811ion transport ----
GO:0006813potassium ion transport TAS10551266
GO:0007268synaptic transmission TAS--
GO:0008016regulation of heart contraction TAS10551266

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Compounds for KCNG2 available from Tocris Bioscience    About this table
CompoundAction CAS #
ICA 110381KV7.2/7.3 activator; displays anticonvulsant properties[325457-99-6]
XE 991 dihydrochloride Potent, selective KV7 (KCNQ) channel blocker; blocks M-current [122955-42-4]
JNJ 303Potent and selective IKs blocker[878489-28-2]
E-4031 dihydrochlorideKV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)[113559-13-0]
ShK-Dap22Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro[220384-25-8]



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for KCNG2 gene: 
NM_012283.1  

Unigene Cluster for KCNG2:

Potassium voltage-gated channel, subfamily G, member 2
Hs.247905
Unigene Representative Sequence: AK308622
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000316249(uc010xfl.2) ENST00000590307
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  QuantiFast Probe-based Assays in human, mouse, rat KCNG2

Additional mRNA sequence: 

AJ011021.1 AK308622.1 

1 DOTS entry:

DT.91683270 

2 AceView cDNA sequences:

NM_012283 AJ011021 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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KCNG2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCCTTCCCGG
KCNG2 Expression
About this image


KCNG2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Endothelium (Cardiovascular System)
         Mature Endothelial Cells Blood Brain Barrier
 
 Brain (Nervous System)
         Mature Endothelial Cells Blood Brain Barrier
 
 Heart (Cardiovascular System)
KCNG2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

KCNG2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.247905

UniProtKB/Swiss-Prot: KCNG2_HUMAN, Q9UJ96
Tissue specificity: Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Detected at low levels
in brain, lung and placenta

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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNG2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for KCNG2 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Kcng21 , 5 potassium voltage-gated channel, subfamily G, member more1, 5 88.86(n)1
91.42(a)1
  18 (53.40 cM)5
2404441  NM_001190373.11  NP_001177302.11 
 802945465 
chicken
(Gallus gallus)
Aves KCNG26
Gallus gallus potassium voltage-gated channel, sub...
57(a)
many ↔ many
2(56365653-56391148)
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 3)
Uncharacterized protein
(see all 3)
57(a)
26(a)
(see all 3)
many ↔ many
many ↔ many
(see all 3)
4(53002745-53036169)
GL343465.1(471595-473706)
zebrafish
(Danio rerio)
Actinopterygii CABZ01045232.16
Uncharacterized protein
52(a)
many ↔ many
19(12129824-12169950) ENSDARG00000035961


ENSEMBL Gene Tree for KCNG2 (if available)
TreeFam Gene Tree for KCNG2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for KCNG2 gene
KCNF12  KCNG32  KCNB22  KCNV12  KCNS22  KCNS32  KCNB12  KCNV22  
KCNG42  KCNG12  KCNS12  
13 SIMAP similar genes for KCNG2 using alignment to 1 protein entry:     KCNG2_HUMAN:
KCNG1    KCNG4    KCNB1    KCNB2    KCNG3    KCNV2
KCNS2    KCNF1    KCNS3    KCNS1    KCNV1    KCND3
KCNA1

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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for KCNG2 (see all 1190)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 18 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1825677991,2
--77621668(+) TAGATG/TAATGT 1 -- us2k10--------
rs47990941,2
C,F,H--77621727(+) tttctT/Cccctg 1 -- us2k1 trp319Minor allele frequency- C:0.27NS EA NA WA 2344
rs1152322901,2
C,F--77621816(+) CCGTTT/ATCTTC 1 -- us2k11Minor allele frequency- A:0.03WA 118
rs1431305221,2
--77621922(+) AGACCC/TTCTAA 1 -- us2k10--------
rs1880389001,2
--77622088(+) GAAATA/CTTTTC 1 -- us2k10--------
rs1511493571,2
--77622251(+) CCCCTA/CTCCCC 1 -- us2k10--------
rs110815691,2
C,F,H--77622356(+) GTTCCA/CATAGC 1 -- us2k129Minor allele frequency- C:0.28NS EA NA WA 3192
rs110815701,2
C,F--77622376(+) AGCAAG/ATGGTG 1 -- us2k18Minor allele frequency- A:0.28NA WA EA 368
rs1930773791,2
--77622407(+) GTCTGA/GAATGA 1 -- us2k10--------
rs1158851701,2
F--77622446(+) TCTGCG/ATGTCT 1 -- us2k11Minor allele frequency- A:0.01WA 118

HapMap Linkage Disequilibrium report for KCNG2 (77623668 - 77660184 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for KCNG2 (see all 37):    About this table    
Variant IDTypeSubtypePubMed ID
esv2666043CNV Deletion23128226
esv2118355CNV Deletion18987734
esv2672923CNV Deletion23128226
esv4697CNV Deletion18987735
esv2674523CNV Deletion23128226
esv2487517CNV Deletion19546169
nsv821139CNV Deletion20802225
esv1026680CNV Deletion17803354
esv1002151CNV Deletion20482838
nsv509710CNV Insertion20534489

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 605696    OMIM disorders: --


Find genes that share disorders with KCNG2           About GenesLikeMe


Export disorders for KCNG2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for KCNG2 gene integrated from 10 sources:
(articles sorted by number of sources associating them with KCNG2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Structural and functional characterization of Kv6.2, a new gamma- subunit of voltage-gated potassium channel. (PubMed id 10551266)1, 2, 3, 9 Zhu X.-R.... Pongs O. (Recept. Channels 1999)
  2. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)1, 3 Gutman G.A....Wang X. (Pharmacol. Rev. 2005)
  3. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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  Query String
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OMIM
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 26251 HGNC: 6249 AceView: KCNG2 Ensembl:ENSG00000178342 euGenes: HUgn26251
ECgene: KCNG2 H-InvDB: KCNG2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for KCNG2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for KCNG2 gene:
Search GeneIP for patents involving KCNG2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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