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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KCNF1 Gene

protein-coding   GIFtS: 55
GCID: GC02P011052

potassium voltage-gated channel, subfamily F, member 1


(Previous symbol: KCNF)
 Explore 5 diseases affiliated with
KCNF1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KCNF1    

Aliases
for KCNF1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Potassium Voltage-Gated Channel, Subfamily F, Member 11 2     KV5.12
KH15     Potassium Channel KH12
IK81 2     Potassium Channel Kv5.12
KCNF1 2     Potassium Voltage-Gated Channel Subfamily F Member 12
Voltage-Gated Potassium Channel Subunit Kv5.12 3     KH15
Kv5.11     

External Ids:    HGNC: 62461   Entrez Gene: 37542   Ensembl: ENSG000001629757   OMIM: 6037875   UniProtKB: Q9H3M03   

Export aliases for KCNF1 gene to outside databases

Previous GC identifers: GC02P010837 GC02P011103 GC02P011073 GC02P011002 GC02P010969


Summaries
for KCNF1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KCNF1:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both
functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart
rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell
volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and
expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: KCNF1_HUMAN, Q9H3M0
Function: Putative voltage-gated potassium channel

summary for KCNF1:
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.

Gene Wiki entry for KCNF1


Genomic Views
for KCNF1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005334.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KCNF1 gene promoter:
         Oct-B1   oct-B2   SREBP-1c   SREBP-1b   CREB   Pax-3   SREBP-1a   deltaCREB   Cart-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KCNF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for KCNF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25   Ensembl cytogenetic band:  2p25.1   HGNC cytogenetic band: 2p25

KCNF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNF1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P011052:  view genomic region     (about GC identifiers)

Start:
 11,052,063 bp from pter      End:
 11,054,351 bp from pter
Size:
 2,289 bases      Orientation:
 plus strand

Proteins
for KCNF1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KCNF1_HUMAN, Q9H3M0 (See protein sequence)
Recommended Name: Potassium voltage-gated channel subfamily F member 1  
Size: 494 amino acids; 55584 Da
Subunit: Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: O43527 Q585L3

Explore the universe of human proteins at neXtProt for KCNF1: NX_Q9H3M0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H3M0

    • KCNF1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002227.2  
    ENSEMBL proteins: 
     ENSP00000295082  
    Reactome Protein details: Q9H3M0
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: KCNF1
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    Novus Biologicals KCNF1 Protein
    Novus Biologicals KCNF1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for KCNF1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0008076voltage-gated potassium channel complex IEA--


    KCNF1 for ontologies           About GeneDecksing



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    Uscn Antibodies for KCNF1
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    Uscn ELISAs and CLIAs for KCNF1

    Protein Domains /
    Families
    for KCNF1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KCNF1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR005821 Ion_trans_dom
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003971 K_chnl_volt-dep_Kv9
     IPR003968 K_chnl_volt-dep_Kv

    Graphical View of Domain Structure for InterPro Entry Q9H3M0

    ProtoNet protein and cluster: Q9H3M0

    3 Blocks protein families:
    IPB000210 BTB/POZ domain
    IPB003091 Potassium channel signature
    IPB003971 Kv9 potassium channel alpha subunit signature


    UniProtKB/Swiss-Prot: KCNF1_HUMAN, Q9H3M0
    Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino
    acids at every third position
    Similarity: Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily


    Function
    for KCNF1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KCNF1_HUMAN, Q9H3M0
    Function: Putative voltage-gated potassium channel

         Genatlas biochemistry entry for KCNF1:
    potassium voltage-gated channel,subfamily G,member 2,rat K13 homolog,expressed in brain,placenta,skeletal muscle with
    an alternatively spliced isoform,also expressed in skeletal muscle

    miRNA
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    hsa-miR-200c* hsa-miR-550a*
    SwitchGear 3'UTR luciferase reporter plasmid: KCNF1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNF1 (see all 4)
    OriGene shRNA RFP: KCNF1
    OriGene siRNA: KCNF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNF1

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for KCNF1

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005249voltage-gated potassium channel activity ----
    GO:0005251delayed rectifier potassium channel activity IBA--
    GO:0005267potassium channel activity TAS9434767


    KCNF1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for KCNF1:
     Increased cell death HMECs cel 

    Animal Models:
         Mouse knock-out Kcnf1tm1Lex for KCNF1
         1 MGI phenotypic allele for Kcnf1 (no phenotypes)

    KCNF1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for KCNF1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Potassium Channels
    		Potassium Channels1.00
    		Voltage gated Potassium channels0.43
    2Dopamine-DARPP32 Feedback onto cAMP Pathway
    		Dopamine-DARPP32 Feedback onto cAMP Pathway1.00
    3Transmission across Chemical Synapses
    		Neuronal System0.67

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KCNF1
        Dopamine-DARPP32 Feedback onto cAMP Pathway

    3        Reactome Pathways for KCNF1
        Potassium Channels
    Neuronal System
    Voltage gated Potassium channels



    KCNF1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KCNF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/41 Interacting proteins for KCNF1 (Q9H3M03 ENSP000002950824) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KCNH1O952593, ENSP000002717514I2D: score=2 STRING: ENSP00000271751
    KCNG3Q8TAE73, ENSP000003041274I2D: score=2 STRING: ENSP00000304127
    KCNG4Q8TDN13, ENSP000003121294I2D: score=1 STRING: ENSP00000312129
    KCNV2Q8TDN23, ENSP000003715144I2D: score=2 STRING: ENSP00000371514
    KCNA10ENSP000003587864STRING: ENSP00000358786
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006813potassium ion transport TAS9434767
    GO:0007268synaptic transmission TAS--
    GO:0051260protein homooligomerization IEA--
    GO:0071805potassium ion transmembrane transport ----


    KCNF1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for KCNF1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for KCNF1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    AM 92016 hydrochlorideKV channel blocker[178894-81-0]
    KN-93CaM kinase II inhibitor. Also K+ channel blocker (KV)[139298-40-1]
    4-AminopyridineNon-selective KV channel blocker[504-24-5]
    Search CenterWatch for drugs/clinical trials and news about KCNF1 

    Transcripts
    for KCNF1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KCNF1 gene: 
    NM_002236.4  

    Unigene Cluster for KCNF1:

    Potassium voltage-gated channel, subfamily F, member 1
    Hs.23735  [show with all ESTs]
    Unigene Representative Sequence: BC026110
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000295082(uc002rax.3)

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: KCNF1
    OriGene siRNA: KCNF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNF1
    Clone
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    GenScript: all cDNA clones in your preferred vector: KCNF1 (NM_002236)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNF1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNF1

    Additional cDNA sequence: 

    AF029780.1 AF033382.1 BC026110.2 

    3 DOTS entries:

    DT.110435  DT.100745018  DT.92416967 

    24/25 AceView cDNA sequences (see all 25):

    NM_002236 AI274992 AI942483 BF516107 AI361583 AF029780 Z38223 BG708997 
    AF033382 AA316752 CB054271 BM714346 BV183403 F04496 CB054272 BC026110 
    BQ549847 R21482 BI757855 AA984726 BQ613980 F05186 R45529 CB155571 

    GeneLoc Exon Structure


    Expression
    for KCNF1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KCNF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCATCGACAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KCNF1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerCholinergic Amacrine CellsAmacrine, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)

    See KCNF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KCNF1

    SOURCE GeneReport for Unigene cluster: Hs.23735

    UniProtKB/Swiss-Prot: KCNF1_HUMAN, Q9H3M0
    Tissue specificity: Detected in heart, brain, liver, skeletal muscle, kidney and pancreas

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNF1

    Orthologs
    for KCNF1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for KCNF1 gene from 4/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves KCNF11 potassium voltage-gated channel, subfamily F, member more 75.86(n)
    85.8(a)    		   428652  XM_426210.2  XP_426210.2 
    lizard
    (Anolis carolinensis)    		 Reptilia KCNF16
    		 --
    		 79(a)
    		 1 ↔ 1
    		 1(147292875-147294344)
    zebrafish
    (Danio rerio)    		 Actinopterygii kcnf1b1 potassium voltage-gated channel, subfamily F, member more 71.67(n)
    75.11(a)    		   100334378  XM_002664189.2  XP_002664235.1 
    honey bee
    (Apis mellifera)    		 Insecta --
    		 --
    		 27(a)
    		 possible ortholog
    		 Group13.15(957-3745)


    ENSEMBL Gene Tree for KCNF1 (if available)
    TreeFam Gene Tree for KCNF1 (if available) 

    Paralogs
    for KCNF1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KCNF1 gene
    KCNG32  KCNB22  KCNV12  KCNG22  KCNS22  KCNS32  KCNB12  KCNV22  
    KCNG42  KCNG12  KCNS12  
    18/21 SIMAP similar genes for KCNF1 using alignment to 1 protein entry:     KCNF1_HUMAN(see all similar genes):
    KCNB1    KCNB2    KCNS2    KCNS3    KCNG4    KCNV2
    KCNV1    KCNG2    KCNG1    KCNG3    KCNS1    KCND2
    KCNA4    KCND1    KCND3    KCNA1    KCNA10    KCNA2

    KCNF1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KCNF1
    PGOHUM00000241817


    Genomic Variants
    for KCNF1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/88 NCBI SNPs in KCNF1 are shown (see all 88)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1144108061,2
    		F,--11050104(+) TATTAT/CCTACT 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1813170121,2
    		--11050168(+) TGCATG/TTGCAC 1 -- us2k10--------
    rs786889821,2
    		F,--11050238(+) GAAGCC/TCATTA 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1507903121,2
    		--11050256(+) ACTAGA/GATGCA 1 -- us2k10--------
    rs1849304311,2
    		--11050276(+) TAACCC/TTGCAG 1 -- us2k10--------
    rs1392145761,2
    		--11050285(+) AGGTAC/GTCGGA 1 -- us2k10--------
    rs1888719751,2
    		--11050439(+) GATCTC/TGGCAG 1 -- us2k10--------
    rs1161109551,2
    		F,--11050454(+) CCTGAC/TATCTT 1 -- us2k11Minor allele frequency- T:0.06WA 118
    rs1816260411,2
    		--11050489(+) TTAAAA/TGACAA 1 -- us2k10--------
    rs731845581,2
    		C,--11050651(+) ACGAAG/ATTTCA 1 -- us2k12Minor allele frequency- A:0.11WA 120

    HapMap Linkage Disequilibrium report for KCNF1 (11052063 - 11054351 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for KCNF1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNF1
    DNA2.0 Custom Variant and Variant Library Synthesis for KCNF1

    Disorders / Diseases
    for KCNF1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KCNF1 for disorders           About GeneDecksing

    OMIM gene information: 603787    OMIM disorders: --

    5 diseases for KCNF1:    About MalaCards
    fragile x syndrome    intellectual disability    neuronitis    fainting
    pharyngitis


    Export disorders for KCNF1 gene to outside databases

    Publications
    for KCNF1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KCNF1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KCNF1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation, characterization, and mapping of two human potassium channels. (PubMed id 9434767)1, 2, 3, 9 Su K.... Li Y. (1997)
    2. International Union of Pharmacology. LIII. Nomenclatu re and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)1, 3 Gutman G.A....Wang X. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    5. Expression, regulation and role of the MAGUK protein SAP-97 in human atrial myocardium. (PubMed id 12445884)2 Godreau D.... Hatem S.N. (2002)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome. (PubMed id 12060745)1 Ottschytsch N.... Snyders D.J. (2002)
    8. Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells. (PubMed id 16815889)9 Fantozzi I....Yuan J.X. (2006)

    External Searches for KCNF1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing KCNF1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3754 HGNC: 6246 AceView: KCNF1 Ensembl:ENSG00000162975 euGenes: HUgn3754
    ECgene: KCNF1 H-InvDB: KCNF1

    Other Databases showing KCNF1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KCNF1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KCNF1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KCNF1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KCNF1 gene:
    Search GeneIP for patents involving KCNF1

    GeneCards and IP:
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