Aliases for KCNF1 Gene
- Potassium Channel, Voltage Gated Modifier Subfamily F, Member 1 2 3
- KH1 3 4 6
- Potassium Voltage-Gated Channel, Subfamily F, Member 1 2 3
- Potassium Channel, Voltage Gated Subfamily F, Member 1 2 3
- Voltage-Gated Potassium Channel Subunit Kv5.1 3 4
- Potassium Voltage-Gated Channel Subfamily F Member 1 3
External Ids for KCNF1 Gene
Previous HGNC Symbols for KCNF1 Gene
Previous GeneCards Identifiers for KCNF1 Gene
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNF1 Gene
KCNF1 (Potassium Channel, Voltage Gated Modifier Subfamily F, Member 1) is a Protein Coding gene. Among its related pathways are Transmission across Chemical Synapses and Dopamine-DARPP32 Feedback onto cAMP Pathway. GO annotations related to this gene include delayed rectifier potassium channel activity and potassium channel activity. An important paralog of this gene is KCNB2.
UniProtKB/Swiss-Prot for KCNF1 Gene
Putative voltage-gated potassium channel
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.