KCNC4 Gene
protein-coding GIFtS: 57
GCID: GC01P110753
|
|
potassium voltage-gated channel, Shaw-related subfamily,...(Previous name: chromosome 1 open reading frame 30 )
(Previous symbol: C1orf30)
| |
Aliases
for KCNC4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 41 2 | | Kv3.41 | | C1orf301 2 | | Chromosome 1 Open Reading Frame 301 | | HKSHIIIC1 2 | | KV3.42 | | Voltage-Gated Potassium Channel Subunit Kv3.42 3 | | K+ Channel Subunit2 | | KSHIIIC2 3 | | Potassium Voltage-Gated Channel Subfamily C Member 42 |
Export aliases for KCNC4 gene to outside databasesPrevious GC identifers: GC01P111170 GC01P109620 GC01P109856 GC01P110052 GC01P110466 GC01P110555 GC01P108626 |
Summaries
for KCNC4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KCNC4:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of foursubfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by thisgene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates thevoltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transientcurrent that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.(provided by RefSeq, Jul 2010)
UniProtKB/Swiss-Prot: KCNC4_HUMAN, Q03721Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assumingopened or closed conformations in response to the voltage difference across the membrane, the protein forms apotassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient
 summary
for KCNC4:Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.
Gene Wiki entry for KCNC4
|
Genomic Views
for KCNC4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNC4 gene promoter:
AP-1 NRSF form 1 c-Jun NRSF form 2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNC4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNC4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p21 Ensembl cytogenetic band: 1p13.3 HGNC cytogenetic band: 1p21KCNC4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P110753: view genomic region
(about GC identifiers)
Start:
|
110,753,336 bp from pter |
End:
|
110,825,722 bp from pter |
Size:
|
72,387 bases |
Orientation:
|
plus strand |
|
Proteins
for KCNC4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNC4_HUMAN, Q03721 (See
protein sequence)Recommended Name: Potassium voltage-gated channel subfamily C member 4 Size: 635 amino acids; 69767 Da
Subunit: Homotetramer (Probable). Heterotetramer of potassium channel proteins (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein
3 PDB 3D structures from  and Proteopedia  for KCNC4:1B4G (3D)
1B4I (3D)
1ZTN (3D)
Secondary accessions: Q3MIM4 Q5TBI6Alternative splicing: 3 isoforms: Q03721-1 Q03721-2 Q03721-3 (Gene prediction based on EST data)Explore the universe of human proteins at neXtProt for KCNC4: NX_Q03721
Post-translational modifications:
Phosphorylation of serine residues in the inactivation gate inhibits rapid channel closure1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q03721
KCNC4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001034663.1 NP_004969.2
ENSEMBL proteins: ENSP00000436656 ENSP00000358802 ENSP00000388029 ENSP00000393655 Reactome Protein details: Q03721
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
KCNC4 for ontologies About GeneDecksing
KCNC4 Antibody Products:
Assay Products for KCNC4: |
Protein
Domains /
Families
for KCNC4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNC4 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q03721ProtoNet protein and cluster: Q03721 4 Blocks protein families: IPB000210 BTB/POZ domain IPB003091 Potassium channel signature IPB003974 Shaw voltage-gated K+ channel family signature IPB005405 Kv3.4 voltage-gated K+ channel signature
UniProtKB/Swiss-Prot: KCNC4_HUMAN, Q03721Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged aminoacids at every third positionDomain: The tail may be important in modulation of channel activity and/or targeting of the channel to specificsubcellular compartmentsSimilarity: Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.4/KCNC4 sub-subfamily |
Function
for KCNC4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KCNC4_HUMAN, Q03721Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assumingopened or closed conformations in response to the voltage difference across the membrane, the protein forms apotassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient Genatlas biochemistry entry for KCNC4:potassium voltage-gated channel,Drosophila Shaw-related subfamily,member 4 (mouse Kv3.4 homolog)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for KCNC4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC4 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
KCNC4 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for KCNC4:
Animal Models:
Mouse knock-out Kcnc4tm1Lex for KCNC4
1 MGI phenotypic allele  for Kcnc4 (no phenotypes)
KCNC4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KCNC4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Potassium Channels | | | 2 | Synaptic transmission: ion currents | | | 3 | Dopamine-DARPP32 Feedback onto cAMP Pathway | | | 4 | Transmission across Chemical Synapses | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for KCNC4
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KCNC4
3 
Reactome Pathways for KCNC4
KCNC4 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KCNC4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/41 Interacting proteins for KCNC4 (ENSP000003588024) via UniProtKB, MINT, STRING, and/or I2D (see all 41)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
KCNC4 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNC4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KCNC4 for compounds About GeneDecksing
Compounds for KCNC4 available from Tocris Bioscience About this table
1 HMDB Compound for KCNC4 About this table
1 DrugBank Compound for KCNC4 About this table
1 Novoseek chemical compound relationship for KCNC4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| potassium |
29.4 |
2 |
1740329 (1), 16449802 (1) |
Search CenterWatch for drugs/clinical trials and news about KCNC4
|
Transcripts
for KCNC4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNC4 gene (3 alternative transcripts): NM_001039574.2 NM_004978.4 NM_153763.2 Unigene Cluster for KCNC4: Potassium voltage-gated channel, Shaw-related subfamily, member 4 Hs.153521 [show with all ESTs]Unigene Representative Sequence: NM_0049787 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000489935(uc001dzf.3) ENST00000469655(uc009wfr.3 uc001dzi.3 uc001dzg.3)
ENST00000369787(uc001dzh.3) ENST00000413138 ENST00000438661 ENST00000412512
ENST00000459877
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KCNC4 (NM_004978) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNC4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC4 |
Additional cDNA sequence: AK125567.1 AK310193.1 BC025377.1 NR_036437.1 7 DOTS entries: DT.311563 DT.409905 DT.307427 DT.100641280 DT.99997196 DT.121387696 DT.40230555 24/96 AceView cDNA sequences (see all 96): BM966756 BX489205 AA298743 CK823243 BM966789 BQ022636 BC025377 AI860726 BM966873 BQ189347 Z38845 BM966921 NM_004978 BX098184 F03407 BM765446 NM_153763 AK125567 AW237067 AI826475 BC019010 BM893568 BQ447832 BM893669
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for KCNC4 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KCNC4
|
Expression
for KCNC4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNC4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTGCTCGA
About this image
See KCNC4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCNC4
SOURCE GeneReport for Unigene cluster: Hs.153521
SABiosciences Custom PCR Arrays for KCNC4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNC4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNC4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNC4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNC4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC4 |
Orthologs
for KCNC4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNC4 gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KCNC41 |
potassium voltage-gated channel, Shaw-related subfamily, more |
78.57(n)
83.14(a) |
|
419806 XM_003642720.1 XP_003642768.1 |
lizard
(Anolis carolinensis) |
Reptilia |
KCNC46KCNB26 |
-- |
76(a)32(a) |
1 ↔ 1possible ortholog |
4(106450817-106472515) 4(146785839-146787137) |
zebrafish
(Danio rerio) |
Actinopterygii |
kcnc41 |
potassium voltage-gated channel, Shaw-related subfamily, more |
71.17(n)
73.62(a) |
|
799410 NM_001195196.1 NP_001182125.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Shaw3 |
potassium ion transport voltage-gated
potassium more |
48(a)
(best of 2) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
shw-33 |
potassium channel protein |
42(a) |
|
V(12975999-12978929) -- |
ENSEMBL Gene Tree for KCNC4 (if available)
TreeFam Gene Tree for KCNC4 (if available) |
Paralogs
for KCNC4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNC4 gene
- KCNA62 KCNA22 KCNC22 KCND22 KCND12 KCNA72 KCNA52 KCNA12
- KCNC12 KCNA42 KCNC32 KCNA32 KCND32 KCNA102
18 SIMAP similar genes for KCNC4 using alignment to 2 protein entries: KCNC4_HUMAN (see all proteins):KCNC1 KCNC2 KCNC3 KCNB1 KCNB2 KCNA1
KCNA10 KCNA2 KCNS1 KCNS3 KCNA7 KCNA3
KCND1 KCNG3 KCNS2 KCND2 KCNV1 KCNA4
KCNC4 for paralogs About GeneDecksing
|
Genomic Variants
for KCNC4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNC4 (110753336 - 110825722 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KCNC4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNC4 |
|
Disorders
/ Diseases
for KCNC4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNC4 for disorders About GeneDecksing
OMIM gene information: 176265
OMIM disorders: --
4  diseases for KCNC4: About MalaCardsneuronitis paralysis alzheimer's disease carcinoma
Export disorders for KCNC4 gene to outside databases
|
Publications
for KCNC4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNC4 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with KCNC4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1. (PubMed id 1740329)1, 3, 9 Ghanshani S....Chandy K.G. (1992)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- International Union of Pharmacology. LIII. Nomenclatu re and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)1, 3 Gutman G.A....Wang X. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interactions between multiple phosphorylation sites in the inactivation particle of a K+ channel. Insights into the molecular mechanism of protein kinase C action. (PubMed id 9649584)1, 2 Beck E.J.... Covarrubias M. (1998)
- Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate. (PubMed id 7993631)1, 2 Covarrubias M.... Vyas T.B. (1994)
- Cloning of a human cDNA expressing a high voltage-activating, TEA-sensitive, type-A K+ channel which maps to chromosome 1 band p21. (PubMed id 1920536)1, 3 Rudy B....Ward D.C. (1991)
- Cell cycle-dependent expression of Kv3.4 channels mod ulates proliferation of human uterine artery smooth muscle cells. (PubMed id 20093253)1, 9 Miguel-Velado E....PAcrez-GarcA-a M.T. (2010)
- Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. (PubMed id 16449802)1, 9 Abbott G.W....Goldstein S.A. (2006)
- Expression and clinical significance of the Kv3.4 pot assium channel subunit in the development and progression of head and neck squa mous cell carcinomas. (PubMed id 20593490)1 MenAcndez S.T....GarcA-a-Pedrero J.M. (2010)
|
External Searches for KCNC4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNC4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNC4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNC4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNC4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KCNC4 gene:
Search GeneIP for patents involving KCNC4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNC4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KCNC4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNC4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNC4 | | | OriGene Protein Over-expression Lysate for KCNC4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KCNC4 | | OriGene 3'-UTR Clone for KCNC4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KCNC4 | | OriGene Custom Protein Services for KCNC4 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNC4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNC4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNC4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNC4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNC4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNC4 |
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| | | | Tocris compounds for KCNC4 |
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 | | | KCNC4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC4 |
|  |  |  | | | | Search ThermoFisher Antibodies for KCNC4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC4 |
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