KCNC3 Gene
protein-coding GIFtS: 60
GCID: GC19M050815
|
|
potassium voltage-gated channel, Shaw-related subfamily,...(Previous name: spinocerebellar ataxia 13 )
(Previous symbol: SCA13)
| |
Aliases
for KCNC3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 31 2 | | Spinocerebellar Ataxia 131 | | SCA131 2 5 | | KV3.32 | | Voltage-Gated Potassium Channel Subunit Kv3.32 3 | | Potassium Voltage-Gated Channel Subfamily C Member 32 | | KSHIIID2 3 | | Shaw-Related Voltage-Gated Potassium Channel Protein 32 | | Kv3.31 | | Voltage-Gated Potassium Channel Protein KV3.32 |
Export aliases for KCNC3 gene to outside databasesPrevious GC identifers: GC19M051447 GC19M051180 GC19M055494 GC19M055510 GC19M047156 |
Summaries
for KCNC3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KCNC3:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of foursubfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shawsubfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is anintegral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KCNC3_HUMAN, Q14003Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assumingopened or closed conformations in response to the voltage difference across the membrane, the protein forms apotassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient
 summary
for KCNC3:Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.
Gene Wiki entry for KCNC3
|
Genomic Views
for KCNC3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNC3 gene promoter:
AhR TBP RREB-1 Pax-2a MIF-1 AP-2gamma Arnt c-Ets-1 COMP1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNC3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNC3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.33 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.33KCNC3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M050815: view genomic region
(about GC identifiers)
Start:
|
50,815,194 bp from pter |
End:
|
50,836,772 bp from pter |
Size:
|
21,579 bases |
Orientation:
|
minus strand |
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Proteins
for KCNC3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNC3_HUMAN, Q14003 (See
protein sequence)Recommended Name: Potassium voltage-gated channel subfamily C member 3 Size: 757 amino acids; 80578 Da
Subunit: Heterotetramer of potassium channel proteins (By similarity)
Subcellular location: Membrane; Multi-pass membrane proteinExplore the universe of human proteins at neXtProt for KCNC3: NX_Q14003
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14003
KCNC3 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_004968.2
ENSEMBL proteins: ENSP00000366158 ENSP00000432438 ENSP00000434241 ENSP00000375694 Reactome Protein details: Q14003
Human Recombinant Protein Products for KCNC3:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
KCNC3 for ontologies About GeneDecksing
KCNC3 Antibody Products:
Assay Products for KCNC3: |
Protein
Domains /
Families
for KCNC3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNC3 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q14003ProtoNet protein and cluster: Q14003 4 Blocks protein families: IPB000210 BTB/POZ domain IPB003091 Potassium channel signature IPB003974 Shaw voltage-gated K+ channel family signature IPB005404 Kv3.3 voltage-gated K+ channel signature
UniProtKB/Swiss-Prot: KCNC3_HUMAN, Q14003Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged aminoacids at every third positionDomain: The tail may be important in modulation of channel activity and/or targeting of the channel to specificsubcellular compartmentsSimilarity: Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.3/KCNC3 sub-subfamily |
Function
for KCNC3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: KCNC3_HUMAN, Q14003Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assumingopened or closed conformations in response to the voltage difference across the membrane, the protein forms apotassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient Genatlas biochemistry entry for KCNC3:potassium voltage-gated channel,Drosophila Shaw-related subfamily,member 3 (mouse Kv3.3 homolog)
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005249 | voltage-gated potassium channel activity |
TAS | 1740329 | | GO:0005251 | delayed rectifier potassium channel activity |
IBA | -- |
KCNC3 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for KCNC3:
7 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Kcnc3):
KCNC3 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Kcnc3tm1Echa for KCNC3
Clone
Products: |  | EMD Millipore Clones for the Expression of KCNC3 | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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Synthesis Service for KCNC3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC3 |
|
Pathways & Interactions
for KCNC3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Potassium Channels | | | 2 | Dopamine-DARPP32 Feedback onto cAMP Pathway | | | 3 | Transmission across Chemical Synapses | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KCNC3
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KCNC3
3 
Reactome Pathways for KCNC3
KCNC3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNC3
1 Interacting protein for KCNC3 (Q140033) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
KCNC3 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNC3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KCNC3 for compounds About GeneDecksing
Compounds for KCNC3 available from Tocris Bioscience About this table
1 HMDB Compound for KCNC3 About this table
1 Novoseek chemical compound relationship for KCNC3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| potassium |
54.4 |
4 |
1740329 (1), 18448641 (1), 19953606 (1) |
Search CenterWatch for drugs/clinical trials and news about KCNC3
|
Transcripts
for KCNC3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNC3 gene: NM_004977.2 Unigene Cluster for KCNC3: Potassium voltage-gated channel, Shaw-related subfamily, member 3 Hs.467146 [show with all ESTs]Unigene Representative Sequence: AB2089304 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000376959(uc002prt.1) ENST00000474951 ENST00000477616(uc002pru.1)
ENST00000391818
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KCNC3 (NM_004977) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNC3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC3 |
Additional cDNA sequence: AB208930.1 AF055989.1 AK127492.1 3 DOTS entries: DT.121420498 DT.401973 DT.92009059 21 AceView cDNA sequences: AW512445 NM_004977 AW148990 AI014603 BI087729 AF055989 AW297613 AI796491 AW173117 AK127492 BE552476 AI346263 AI365599 AA860973 AA767342 CD244420 BG991639 H16352 BM474777 BU101932 CB152030
GeneLoc Exon Structure
|
Expression
for KCNC3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNC3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCCTTCCC
About this image
Genevestigator expression for KCNC3
SOURCE GeneReport for Unigene cluster: Hs.467146
SABiosciences Expression via Pathway-Focused PCR Array including KCNC3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNC3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNC3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNC3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNC3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC3 |
Orthologs
for KCNC3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNC3 gene from 6/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Kcnc31 , 5 |
potassium voltage gated channel, Shaw-related subfamily, more1, 5 |
88.55(n)1
95.84(a)1 |
|
7 (28.85 cM)5
165041 NM_008422.21 NP_032448.21
445906645 |
lizard
(Anolis carolinensis) |
Reptilia |
KCNC36KCNB26 |
-- |
82(a)32(a) |
1 ↔ 1possible ortholog |
GL343287.1(213314-226747) 4(146785839-146787137) |
African clawed frog
(Xenopus laevis) |
Amphibia |
kcnc3-A2 |
potassium voltage-gated channel, Shaw-related subfamily, more |
76.57(n) |
|
AF132853.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
kcnc3b1 |
potassium voltage-gated channel, Shaw-related subfamily, more |
74.02(n)
77.05(a) |
|
564371 NM_001195241.1 NP_001182170.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Shaw3 |
potassium ion transport voltage-gated
potassium more |
47(a)
(best of 2) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
shw-33 |
potassium channel protein |
44(a) |
|
V(12975999-12978929) -- |
ENSEMBL Gene Tree for KCNC3 (if available)
TreeFam Gene Tree for KCNC3 (if available) |
Paralogs
for KCNC3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNC3 gene
- KCNA62 KCNA22 KCNC22 KCNC42 KCND22 KCND12 KCNA72 KCNA52
- KCNA12 KCNC12 KCNA42 KCNA32 KCND32 KCNA102
9 SIMAP similar genes for KCNC3 using alignment to 4 protein entries: KCNC3_HUMAN (see all proteins):KCNC1 KCNC2 KCNC4 KCNA10 KCNA4 KCNS1
KCNS3 KCNA1 KCNS2
KCNC3 for paralogs About GeneDecksing
|
Genomic Variants
for KCNC3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNC3 (50815194 - 50836772 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KCNC3: --
Human Gene Mutation Database (HGMD): KCNC3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNC3 |
|
Disorders
/ Diseases
for KCNC3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNC3 for disorders About GeneDecksing
OMIM gene information: 176264
OMIM disorders: 605259
UniProtKB/Swiss-Prot: KCNC3_HUMAN, Q14003
Defects in KCNC3 are the cause of spinocerebellar ataxia type 13 (SCA13) [MIM:605259]. Spinocerebellar ataxiais a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordinationof gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum withvariable involvement of the brainstem and spinal cord. SCA13 is an autosomal dominant cerebellar ataxia (ADCA)characterized by slow progression and variable age at onset, ranging from childhood to late adulthood. Mentalretardation can be present in some patients
10  diseases for KCNC3: About MalaCardsspinocerebellar ataxia spinocerebellar ataxia type 13 ataxia spinocerebellar ataxia type13
cerebellar ataxia with mental retardation cerebellar ataxia huntington's disease lung carcinoma
carcinoma neuronitis
2 diseases from the University of Copenhagen DISEASES database for KCNC3:Spinocerebellar ataxia Cerebellar ataxia GeneTests: KCNC3
Spinocerebellar Ataxia Type13
Human Genome Epidemiology (HuGE) Navigator: KCNC3 (1 document)
Export disorders for KCNC3 gene to outside databases
|
Publications
for KCNC3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNC3 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with KCNC3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1. (PubMed id 1740329)1, 3, 9 Ghanshani S....Chandy K.G. (1992)
- Localization of Shaw-related K+ channel genes on mouse and human chromosomes. (PubMed id 8111118)1, 3, 9 Haas M.... Rudy B. (1993)
- Kv3.3 potassium channels in lens epithelium and corneal endothelium. (PubMed id 10712820)1, 2, 9 Rae J.L. and Shepard A.R. (2000)
- Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental nervous system phenotypes. (PubMed id 16501573)1, 2 Waters M.F.... Pulst S.M. (2006)
- International Union of Pharmacology. LIII. Nomenclatu re and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)1, 3 Gutman G.A....Wang X. (2005)
- KCNC3: phenotype, mutations, channel biophysics-a stu dy of 260 familial ataxia patients. (PubMed id 19953606)1, 9 Figueroa K.P....Pulst S.M. (2010)
- Altered Kv3.3 channel gating in early-onset spinocereb ellar ataxia type 13. (PubMed id 22289912)1 Minassian N.A....Papazian D.M. (2012)
- Spinocerebellar ataxia 13 and 25. (PubMed id 21827913)1 Stevanin G. and DA1rr A. (2012)
- Spinocerebellar ataxia type 13 mutant potassium chann el alters neuronal excitability and causes locomotor deficits in zebrafish. (PubMed id 21543613)1 Issa F.A....Papazian D.M. (2011)
- Frequency of KCNC3 DNA variants as causes of spinocer ebellar ataxia 13 (SCA13). (PubMed id 21479265)1 Figueroa K.P....Pulst S.M. (2011)
|
External Searches for KCNC3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNC3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNC3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNC3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNC3 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/KCNC3 |
|
| | |
About This Section
| Patent Information for KCNC3 gene:
Search GeneIP for patents involving KCNC3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNC3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for KCNC3 | | OriGene shRNA RFP for KCNC3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNC3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNC3 | | | OriGene Protein Over-expression Lysate for KCNC3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KCNC3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNC3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KCNC3 | | OriGene Custom Protein Services for KCNC3 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNC3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNC3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNC3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNC3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNC3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNC3 |
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| | | | Tocris compounds for KCNC3 |
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 | | | KCNC3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNC3 |
|  |  |  |  | | | | ThermoFisher Antibodies for KCNC3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNC3 |
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