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KCNC1 Gene

protein-coding GIFtS: 59

GC11P017712

potassium voltage-gated channel, Shaw-related subfamily, member 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ41162 ^²
FLJ42249 ^²
FLJ43491 ^²
KV3.1 ^²
KV4 ^²
Kv3.1 ^¹
Kv4 ^³
MGC129855 ^²
NGK2 ^², ³

Descriptions
Shaw-related voltage-gated potassium channel protein 1 ^²
Voltage-gated potassium channel subunit Kv3.1 ^³
potassium voltage-gated channel subfamily C member 1 ^²
potassium voltage-gated channel, Shaw-related subfamily, member 1 ^²
voltage-gated potassium channel protein KV3.1 ^²

External Ids
HGNC: 6233¹
Entrez Gene: 3746²
UniProtKB: P48547³
Ensembl: ENSG00000129159⁷

Search outside databases for aliases for KCNC1 gene

Previous GC identifers: GC11P018878 GC11P018699 GC11P017796 GC11P017721 GC11P017681

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KCNC1:

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is

comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these

subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed

rectifier class of channel proteins and is an integral membrane protein that mediates the

voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants

encoding different isoforms have been inferred for this gene based on orthologous loci. [provided

by RefSeq]

UniProtKB/Swiss-Prot: KCNC1_HUMAN, P48547

Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes.

Assuming opened or closed conformations in response to the voltage difference across the membrane,

the protein forms a potassium-selective channel through which potassium ions may pass in

accordance with their electrochemical gradient

Gene Wiki entry for KCNC1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the KCNC1 gene

Entrez Gene cytogenetic band: 11p15 Ensembl cytogenetic band: 11p15.1 HGNC cytogenetic band: 11p15

KCNC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P017712: (about GC identifiers)

Start:	17,714,090 bp from pter
End:	17,750,755 bp from pter
Size:	36,666 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_009237.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: KCNC1_HUMAN, P48547 (See protein sequence)

Recommended Name: Potassium voltage-gated channel subfamily C member 1

Size: 511 amino acids; 57942 Da

Subunit: Heteromultimer with KCNG3, KCNG4 and KCNV2

Subcellular location: Membrane; Multi-pass membrane protein

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001106212.1 NP_004967.1

ENSEMBL proteins:

ENSP00000265969

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KCNC1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008076	voltage-gated potassium channel complex	TAS	1400413
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for KCNC1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of KCNC1
	Sigma-Aldrich Antibodies for KCNC1
	R&D Systems Antibodies for KCNC1 (Potassium Channel Kv3.1)
	Antibodies from Abcam (KCNC1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for KCNC1

Assays for KCNC1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P48547

ProtoNet protein and cluster: P48547

4 Blocks protein families:

IPB000210 BTB/POZ domain

IPB003091 Potassium channel signature

IPB003974 Shaw voltage-gated K+ channel family signature

IPB005403 Kv3.1 voltage-gated K+ channel signature

UniProtKB/Swiss-Prot: KCNC1_HUMAN, P48547

Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of

positively charged amino acids at every third position

Domain: The tail may be important in modulation of channel activity and/or targeting of the channel

to specific subcellular compartments

Similarity: Belongs to the potassium channel family. C (Shaw) subfamily

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNC1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNC1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_004976

Applied Biosystems Silencer® siRNAs for KCNC1

Sigma-Aldrich siRNA and siRNA Panels for KCNC1

Sigma-Aldrich shRNA Panels and shRNA for KCNC1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001112741
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001112741
untagged cDNA clones in CMV expression vector (see all 3): NM_001112741

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001112741

UniProtKB/Swiss-Prot: KCNC1_HUMAN, P48547

Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes.

Assuming opened or closed conformations in response to the voltage difference across the membrane,

the protein forms a potassium-selective channel through which potassium ions may pass in

accordance with their electrochemical gradient

Genatlas biochemistry entry for KCNC1:

potassium voltage-gated channel,Drosophila Shaw-related family,member 1 (mouse Kv3.1 homolog)

4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Kcnc1):

behavior/neurological

growth/size

muscle

nervous system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005244	voltage-gated ion channel activity	IEA	--
GO:0005249	voltage-gated potassium channel activity	TAS	8449507
GO:0005515	protein binding	IEA	--
GO:0030955	potassium ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for KCNC1

5/50 Interacting proteins for KCNC1 (ENSP00000265969³) via UniProtKB, MINT, and/or STRING (see all 50 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KCNIP2	ENSP00000347877³	STRING (score=.995)
KCNH2	ENSP00000262186³	STRING (score=.978)
FREQ	ENSP00000361475³	STRING (score=.972)
KCNH1	ENSP00000271751³	STRING (score=.968)
KCNE1	ENSP00000337255³	STRING (score=.967)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0006813	potassium ion transport	TAS	8449507

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for KCNC1 available from Tocris Bioscience

Compound	Action	CAS number
Chromanol 293B	IKs blocker. Also blocks ICFTR	[163163-23-3]
AM 92016 hydrochloride	KV channel blocker	[178894-81-0]
KN-93	CaM kinase II inhibitor. Also K+ channel blocker (KV)	[139298-40-1]
(-)-[3R,4S]-Chromanol 293B	IKs blocker. Enantiomer of (Cat. No. 1412)	[163163-24-4]
4-Aminopyridine	K+ channel blocker	[504-24-5]

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1 Novoseek chemical compound relationship for KCNC1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
potassium	61.42	4	1400413 (1), 8449507 (1), 1607925 (1), 17242957 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KCNC1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KCNC1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_004976

Sigma-Aldrich siRNA and siRNA Panels for KCNC1

Sigma-Aldrich shRNA Panels and shRNA for KCNC1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001112741 NM_004976

REFSEQ mRNAs for KCNC1 gene (2 alternative transcripts):

NM_001112741.1 NM_004976.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001112741 NM_004976

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001112741
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001112741
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001112741

Additional cDNA sequence:

AK123157.1 AK124243.1 AK125480.1 BC107129.2 L00621.1 M96747.1 S56770.1

7 DOTS entries:

DT.436620 DT.91834707 DT.40206707 DT.97829556 DT.120700095 DT.91720841 DT.95244524

5 AceView cDNA sequences:

M96747 CK903961 BM053045 BQ187015 H19662

highest scoring ESTs for KCNC1:

S56770 AW898499 BG707883 BI490132 BQ187015 BX090988 H19662 H50388 L00621 M96747

Unigene Cluster for KCNC1:

Potassium voltage-gated channel, Shaw-related subfamily, member 1

Hs.552896 [show with all ESTs]

Unigene Representative Sequence: NM_004976

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000265969

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KCNC1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KCNC1

¹ / ² / ³

6 probe-sets matching KCNC1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32322_at²^{, 3}	U95-A	1	1.00	1.00	0.93	0.53	S56770	1.00	1.00	1.00	1
43443_at²	U95-B	2	0.94	0.50	0.87	1.51	--	--	--	--	--
208477_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004976	0.60	1.00	0.82	1
230547_at²	U133-B	2	1.00	0.50	--	--	--	--	--	--	--
208477_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
230547_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks KCNC1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.552896
Expression variation in blood from EXPOLDB for KCNC1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KCNC1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KCNC1¹	--	potassium voltage-gated channel, Shaw-related subfamily, more	94.91(n) 98.61(a)	403705 NM_001003113.1 NP_001003113.1
chimpanzee (Pan troglodytes)	KCNC1¹	--	potassium voltage-gated channel, Shaw-related subfamily, more	99.6(n) 99.6(a)	466452 XM_001172719.1 XP_001172719.1
cow (Bos taurus)	KCNC1¹	--	potassium voltage-gated channel, Shaw-related subfamily, more	95.04(n) 99.41(a)	541459 NM_001013605.1 NP_001013623.1
rat (Rattus norvegicus)	Kcnc1¹	--	potassium voltage gated channel, Shaw-related subfamily, more	93.12(n) 99.4(a)	25327 NM_012856.1 NP_036988.1
mouse (Mus musculus)	Kcnc1^{1, 5}	7 (23.50 cM)⁵	potassium voltage gated channel, Shaw-related subfamily, more^{1, 5}	93.67(n)¹ 99.8(a)¹	16502¹ NM_008421.2¹ NP_032447.1¹ AI848070⁵ AK079373⁵ (see all 17)

About this table Species with no ortholog for KCNC1

ENSEMBL Gene Tree for KCNC1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KCNC1 gene

KCNC2² KCNC4² KCNC3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/212 NCBI SNPs in KCNC1 are shown (see all 212 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 77)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1236205^1,2	A,C,F,H,O	17760287(+)	`CGTTCA/GGTAGA`	1	--	ut3¹		12		MN EU EA WA NA	1162
	rs4757586^1,2	A,C,F,H	17712093(+)	`CAGCTC/TATCAC`	1	--	ng5¹		4		EU EA WA	408
	rs12574348^1,2	C,F,H	17752305(+)	`GTCTCC/TGAGGC`	1	--	ut3¹		8		EU EA WA	840
	rs11024394^1,2	C,F,H	17751014(+)	`AACTTA/GGCAGG`	1	--	ut3¹		4		EU EA WA	406
--	rs12806830^1,2	H	17750319(+)	`CCGAGA/TGGATA`	2	R/W	mis¹ ese³		4		EU EA WA	402
	rs3858514^1,2	A	17712108(+)	`GGCAGC/TTGAAG`	1	--	ng5¹		0	--	--	--	--
	rs12421233^1,2	C	17753568(+)	`GGCTTG/TTCCTG`	1	--	ut3¹		0	--	--	--	--
	rs2229007^1,2	C,F,H	17749961(+)	`TACATC/TGAGGG`	2	I/I	syn¹ ese³		9		MN EU EA WA NA	646
	rs757514^1,2	A,C,F,H,O	17727524(-)	`TATGGC/TAGCCC`	1	--	int¹		22		NA EA EU WA	1711
	rs757511^1,2	A,C,F,H,O	17731049(-)	`AACCAT/CCTCCA`	1	--	int¹		22		NA EA EU WA	1785

About this table

HapMap Linkage Disequilibrium images for KCNC1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 176258

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/22 PubMed articles for KCNC1 gene (see all 22 ):

Localization of a highly conserved human potassium channel gene (NGK2-KV4; KCNC1) to chromosome 11p15. (PubMed id 8449507)^{1, 2, 3, 4} Ried T.... Sen K. (1993)
The Shaw-related potassium channel gene, Kv3.1, on human chromosome 11, encodes the type l K+ channel in T cells. (PubMed id 1400413)^{1, 3, 4} Grissmer S.... Chandy K.G. (1992)
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. (PubMed id 16382104)^{2, 3} Gutman G.A....Wang X. (2005)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. (PubMed id 17053785)⁴ Wang Y.... Chen Z. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Kv3.1b is a novel component of CNS nodes. (PubMed id 12805291)³ Devaux J....Scherer S.S. (2003)
Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome. (PubMed id 12060745)³ Ottschytsch N.... Snyders D.J. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits. (PubMed id 7559593)³ Xu J....Li M. (1995)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3746	HGNC: 6233	AceView: KCNC1	Ensembl:ENSG00000129159	euGenes: HUgn3746
ECgene: KCNC1	H-InvDB: KCNC1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KCNC1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KCNC1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KCNC1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KCNC1		Antibodies for KCNC1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KCNC1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Tocris compounds for KCNC1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for KCNC1

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KCNC1 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for KCNC1

Summaries
for KCNC1

Genomic Location
for KCNC1

Proteins
for KCNC1

Protein Domains/
Families
for KCNC1

Gene Function
for KCNC1

Pathways & Interactions
for KCNC1

Drugs & Compounds
for KCNC1

Transcripts
for KCNC1

Expression
for KCNC1

Orthologs
for KCNC1

Paralogs
for KCNC1

SNPs/Variants
for KCNC1

Disorders & Mutations
for KCNC1

Medical News
for KCNC1

Publications
for KCNC1

Search for KCNC1

Genome Databases showing KCNC1

Other Databases showing KCNC1

Specialized Databases showing KCNC1

Licensable Technologies
for KCNC1

Services
for KCNC1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KCNC1 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor KCNC1

Summariesfor KCNC1

Genomic Locationfor KCNC1

Proteinsfor KCNC1

Protein Domains/Familiesfor KCNC1

Gene Functionfor KCNC1

Pathways & Interactionsfor KCNC1

Drugs & Compoundsfor KCNC1

Transcriptsfor KCNC1

Expression for KCNC1

Orthologsfor KCNC1

Paralogsfor KCNC1

SNPs/Variantsfor KCNC1

Disorders & Mutationsfor KCNC1

Medical Newsfor KCNC1

Publicationsfor KCNC1

Search for KCNC1

Genome Databases showing KCNC1

Other Databases showing KCNC1

Specialized Databases showing KCNC1

Licensable Technologiesfor KCNC1

Servicesfor KCNC1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KCNC1

Summaries
for KCNC1

Genomic Location
for KCNC1

Proteins
for KCNC1

Protein Domains/
Families
for KCNC1

Gene Function
for KCNC1

Pathways & Interactions
for KCNC1

Drugs & Compounds
for KCNC1

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