Aliases for KCNB2 Gene
Aliases for KCNB2 Gene
- Potassium Voltage-Gated Channel Subfamily B Member 2 2 3 5
- Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 2 3
- Voltage-Gated Potassium Channel Subunit Kv2.2 3 4
- Potassium Channel, Voltage Gated Shab Related Subfamily B, Member 2 3
- Delayed Rectifier Potassium Channel Protein 3
- Potassium Channel Kv2.2 3
- KV2.2 3
External Ids for KCNB2 Gene
- HGNC: 6232
- Entrez Gene: 9312
- Ensembl: ENSG00000182674
- OMIM: 607738
- UniProtKB: Q92953
Previous GeneCards Identifiers for KCNB2 Gene
- GC08P073420
- GC08P073172
- GC08P073499
- GC08P073612
- GC08P068946
Summaries for KCNB2 Gene
-
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNB2 Gene
KCNB2 (Potassium Voltage-Gated Channel Subfamily B Member 2) is a Protein Coding gene. Diseases associated with KCNB2 include Brugada Syndrome. Among its related pathways are Transmission across Chemical Synapses and Potassium Channels. Gene Ontology (GO) annotations related to this gene include ion channel activity and delayed rectifier potassium channel activity. An important paralog of this gene is KCNB1.
UniProtKB/Swiss-Prot for KCNB2 Gene
-
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. Homotetrameric channels mediate a delayed-rectifier voltage-dependent outward potassium current that display rapid activation and slow inactivation in response to membrane depolarization. Can form functional homotetrameric and heterotetrameric channels that contain variable proportions of KCNB1; channel properties depend on the type of alpha subunits that are part of the channel. Can also form functional heterotetrameric channels with other alpha subunits that are non-conducting when expressed alone, such as KCNS1 and KCNS2, creating a functionally diverse range of channel complexes. In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member. Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells.
-
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNB2 Gene
Genomics for KCNB2 Gene
GeneHancer (GH) Regulatory Elements for KCNB2 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH08I072536 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 550.8 | -0.2 | -178 | 1 | MXI1 KLF1 ZBTB6 MZF1 ZNF76 ZIC2 ZNF2 ZNF335 ZFHX2 GATA3 | KCNB2 LOC105375897 | |
GH08I072537 | Enhancer | 0.7 | ENCODE | 550.8 | +0.6 | 610 | 0.2 | ZBTB10 MXI1 MAZ ZNF189 MZF1 ZNF76 ZBTB8A ZIC2 ZNF335 GLIS2 | KCNB2 GC08M072619 | |
GH08I072538 | Enhancer | 0.6 | ENCODE | 550.8 | +0.8 | 830 | 0.1 | ZNF335 MXI1 ZNF76 ZNF600 ZBTB8A EZH2 ZBTB20 ZBTB17 | KCNB2 GC08M072619 | |
GH08I072693 | Enhancer | 0.2 | FANTOM5 | 11.7 | +155.8 | 155835 | 0.1 | KCNB2 TERF1 LOC100419613 LOC101926908 | ||
GH08I072607 | Enhancer | 0.3 | FANTOM5 | 7.7 | +70.2 | 70162 | 0.4 | EZH2 | KCNB2 GC08M072619 |
Regulatory Element Products
Genomic Locations for KCNB2 Gene
- chr8:72,537,391-72,938,349
- (GRCh38/hg38)
- Size:
- 400,959 bases
- Orientation:
- Plus strand
- chr8:73,449,626-73,850,584
- (GRCh37/hg19)
Genomic View for KCNB2 Gene
- Cytogenetic band:
-
- 8q21.11 by Ensembl
- 8q21.11 by Entrez Gene
- 8q21.11 by HGNC


RefSeq DNA sequence for KCNB2 Gene
Proteins for KCNB2 Gene
-
Protein details for KCNB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92953-KCNB2_HUMAN
- Recommended name:
- Potassium voltage-gated channel subfamily B member 2
- Protein Accession:
- Q92953
- Q7Z7D0
- Q9BXD3
Protein attributes for KCNB2 Gene
- Size:
- 911 amino acids
- Molecular mass:
- 102563 Da
- Quaternary structure:
-
- Homotetramer or heterotetramer with KCNB1. Heterotetramer with KCNS1 and KCNS2.
- SequenceCaution:
-
- Sequence=AAB08433.1; Type=Frameshift; Positions=768; Evidence={ECO:0000305};
Protein Expression for KCNB2 Gene
Post-translational modifications for KCNB2 Gene
- Phosphorylated.
- Glycosylation at isoforms=287
Other Protein References for KCNB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
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No data available for DME Specific Peptides for KCNB2 Gene
Domains & Families for KCNB2 Gene
Gene Families for KCNB2 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- FDA approved drug targets
- Predicted membrane proteins
- Voltage-gated ion channels
Protein Domains for KCNB2 Gene
Suggested Antigen Peptide Sequences for KCNB2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q92953UniProtKB/Swiss-Prot:
KCNB2_HUMAN :- The transmembrane segment S4 functions as voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.
- Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
- Domain:
-
- The transmembrane segment S4 functions as voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.
- Family:
-
- Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
Function for KCNB2 Gene
Molecular function for KCNB2 Gene
- GENATLAS Biochemistry:
- potassium voltage-gated channel,Drosophila Shab-related subfamily,member 2,expressed in (canine) gastrointestinal smooth muscles
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: Note=Homotetrameric channels expressed in xenopus oocytes or in mammalian non-neuronal cells display delayed-rectifier voltage- dependent potassium currents which are activated during membrane depolarization, i.e within a risetime of about 20 msec. After that, inactivate very slowly. Their activation requires low threshold potentials of about -20 to -30 mV, with a midpoint activation at about 10 mV. For inactivation, the voltage at half-maximal amplitude is about -30 mV. Channels have an unitary conductance of about 14 pS. The voltage-dependence of activation and inactivation and other channel characteristics vary depending on the experimental conditions, the expression system and post-translational modifications. {ECO:0000250 UniProtKB:Q63099, ECO:0000305 PubMed:10414301};
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Inhibited by quinine at micromolar levels. Modestly sensitive to millimolar levels of tetraethylammonium (TEA) and 4-aminopyridine (4-AP).
- UniProtKB/Swiss-Prot Function:
- Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. Homotetrameric channels mediate a delayed-rectifier voltage-dependent outward potassium current that display rapid activation and slow inactivation in response to membrane depolarization. Can form functional homotetrameric and heterotetrameric channels that contain variable proportions of KCNB1; channel properties depend on the type of alpha subunits that are part of the channel. Can also form functional heterotetrameric channels with other alpha subunits that are non-conducting when expressed alone, such as KCNS1 and KCNS2, creating a functionally diverse range of channel complexes. In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member. Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells.
Phenotypes From GWAS Catalog for KCNB2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005244 | voltage-gated ion channel activity | IEA | -- |
GO:0005249 | voltage-gated potassium channel activity | IBA | -- |
GO:0005251 | delayed rectifier potassium channel activity | TAS,ISS | -- |
GO:0005267 | potassium channel activity | IEA | -- |
GO:0046982 | protein heterodimerization activity | ISS | -- |
Phenotypes for KCNB2 Gene
- MGI mutant phenotypes for KCNB2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for KCNB2:
Animal Models for KCNB2 Gene
- MGI Knock Outs for KCNB2:
-
- Kcnb2 tm1Lex
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miRNA for KCNB2 Gene
- miRTarBase miRNAs that target KCNB2
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Cell Line Products
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Horizon Cell Lines for KCNB2
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KCNB2 Gene
Localization for KCNB2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNB2 Gene
- Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Note=Localized uniformly throughout cell bodies and dendrites. Colocalizes with KCNB1 to high-density somatodendritic clusters on cortical pyramidal neurons. {ECO:0000250 UniProtKB:Q63099}.
- Midbody (2)
- Nucleoli (2)
- Plasma membrane (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0008076 | voltage-gated potassium channel complex | ISS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IBA | -- |
GO:0030425 | dendrite | ISS | -- |
Pathways & Interactions for KCNB2 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Potassium Channels | ||
2 | Dopamine-DARPP32 Feedback onto cAMP Pathway | ||
3 | Transmission across Chemical Synapses |
.62
|
Pathways by source for KCNB2 Gene
3 Reactome pathways for KCNB2 Gene
1 Qiagen pathway for KCNB2 Gene
Interacting Proteins for KCNB2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006810 | transport | IEA | -- |
GO:0006811 | ion transport | IEA | -- |
GO:0006813 | potassium ion transport | TAS,ISS | -- |
GO:0006940 | regulation of smooth muscle contraction | TAS | 9612272 |
GO:0034765 | regulation of ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for KCNB2 Gene
Drugs & Compounds for KCNB2 Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
4-Aminopyridine | Approved | Pharma | Pore Blocker, Target, antagonist | potassium channel-blocking agent | 73 | |
Quinine | Approved | Pharma | Pore Blocker, blocker | 47 | ||
tetraethylammonium | Experimental, Investigational | Pharma | Inhibitor | 1 | ||
fampridine | Pharma | 0 | ||||
GXTX-1E | Pharma | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
---|
(4) Tocris Compounds for KCNB2 Gene
Compound | Action | Cas Number |
---|---|---|
Chromanol 293B | IKs blocker. Also blocks ICFTR | 163163-23-3 |
Flupirtine maleate | KV7 channel activator | 75507-68-5 |
Kaliotoxin | KV and KCa blocker | 145199-73-1 |
MaxiPost | Potassium channel modulator; exerts subtype-specific effects | 187523-35-9 |
Transcripts for KCNB2 Gene
mRNA/cDNA for KCNB2 Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (5) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KCNB2 Gene
CRISPR Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available KCNB2 gene related products
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 |
---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||
SP2: | - | - | - |
Expression for KCNB2 Gene
mRNA differential expression in normal tissues according to GTEx for KCNB2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KCNB2 Gene
NURSA nuclear receptor signaling pathways regulating expression of KCNB2 Gene:
KCNB2SOURCE GeneReport for Unigene cluster for KCNB2 Gene:
Hs.661102Evidence on tissue expression from TISSUES for KCNB2 Gene
- Nervous system(4.4)
Primer Products
-
OriGene qPCR primer pairs for KCNB2
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNB2 Gene
Orthologs for KCNB2 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | KCNB2 33 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | KCNB2 34 |
|
OneToOne | |
rat (Rattus norvegicus) |
Mammalia | Kcnb2 33 |
|
||
mouse (Mus musculus) |
Mammalia | Kcnb2 33 16 34 |
|
||
cow (Bos Taurus) |
Mammalia | KCNB2 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | KCNB2 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | KCNB2 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | KCNB2 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | KCNB2 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | kcnb2 33 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | kcnb2-B 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | KCNB2 (2 of 2) 34 |
|
OneToMany | |
kcnb2 34 |
|
OneToMany | |||
LOC566883 33 |
|
||||
fruit fly (Drosophila melanogaster) |
Insecta | Shab 35 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | exp-2 35 |
|
|
|
Y48A6B.6 35 |
|
|
|||
C32C4.1 35 |
|
|
|||
F44A2.2 35 |
|
|
|||
Y55F3C.3 35 |
|
|
|||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.14250 33 |
|
- Species where no ortholog for KCNB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for KCNB2 Gene
Paralogs for KCNB2 Gene
(23) SIMAP similar genes for KCNB2 Gene using alignment to 1 proteins:
Variants for KCNB2 Gene
SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs770305852 | A colorectal cancer sample | 72,936,703(+) | G/A | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
rs1000003398 | -- | 72,727,347(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
rs1000039841 | -- | 72,546,860(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
rs1000045124 | -- | 72,849,442(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
rs1000056585 | -- | 72,611,192(+) | A/G | genic_upstream_transcript_variant, intron_variant |
Additional Variant Information for KCNB2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNB2 Gene
Disorders for KCNB2 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
brugada syndrome |
|
|
Additional Disease Information for KCNB2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for KCNB2 Gene
Publications for KCNB2 Gene
- Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles. (PMID: 9612272) Schmalz F … Horowitz B (The American journal of physiology 1998) 2 3 4 22 58
- A high-density association screen of 155 ion transport genes for involvement with common migraine. (PMID: 18676988) Nyholt DR … Palotie A (Human molecular genetics 2008) 3 22 44 58
- Common genetic variation and performance on standardized cognitive tests. (PMID: 20125193) Cirulli ET … Goldstein DB (European journal of human genetics : EJHG 2010) 3 44 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PMID: 19010793) Baranzini SE … Oksenberg JR (Human molecular genetics 2009) 3 44 58
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- Plasmid Preparation
- GenScript Custom Peptide Services for KCNB2
- Browse Sino Biological cDNA Clones
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for KCNB2
- Novus Biologicals proteins for KCNB2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for KCNB2
- Find your target
- Browse Primary Antibodies
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- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for KCNB2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNB2
- VectorBuilder custom plasmid, inducible vectors for KCNB2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNB2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 70 available KCNB2 Antibodies ranked by validation data
- Compare Top KCNB2 Antibodies
- antibodies-online: Search results for 9 available KCNB2 Elisa Kits ranked by validation data
- Compare Top KCNB2 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 6 available KCNB2 Proteins ranked by validation data
- Compare Top KCNB2 Proteins
- Quality Products:
- Search GeneTex for Antibodies for KCNB2
- Search GeneTex for Proteins for KCNB2
- ViGene Biosciences adenoviral particle packaged cDNA for KCNB2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for KCNB2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KCNB2 gene
- Search ViGene Biosciences for KCNB2
- Santa Cruz Biotechnology (SCBT) Antibodies for KCNB2
- Search Santa Cruz Biotechnology (SCBT) for KCNB2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KCNB2
- Horizon Cell Lines for KCNB2
- genomics-online: cdna clones - Search results for available KCNB2 gene related products
- orf clones - Search results for available KCNB2 gene related products
- genomics-online: gRNA clones - Search results for available KCNB2 gene related products
- genomics-online: primer clones - Search results for available KCNB2 gene related products
- genomics-online: shRNA clones - Search results for available KCNB2 gene related products
Sources for KCNB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew