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KCNAB3 Gene

protein-coding   GIFtS: 52
GCID: GC17M007825

Potassium Voltage-Gated Channel, Shaker-Related Subfamily,...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Beta Member
31 2
     KV-BETA-32
KCNA3B2 3 5     Potassium Channel, Voltage-Dependent, Beta-3 Subunit2
K(+) Channel Subunit Beta-32 3     Voltage-Gated Potassium Channel Subunit Beta-32
AKR6A92     Kv-beta-33
KCNA3.1B2     

External Ids:    HGNC: 62301   Entrez Gene: 91962   Ensembl: ENSG000001700497   OMIM: 6041115   UniProtKB: O434483   

Export aliases for KCNAB3 gene to outside databases

Previous GC identifers: GC17M008292 GC17M008697 GC17M007768 GC17M008026 GC17M007766 GC17M007720


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KCNAB3 Gene:
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein
is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The
encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5
gene product and regulates the activity of the alpha subunit. (provided by RefSeq, May 2012)

GeneCards Summary for KCNAB3 Gene:
KCNAB3 (potassium voltage-gated channel, shaker-related subfamily, beta member 3) is a protein-coding gene. GO annotations related to this gene include potassium channel regulator activity and voltage-gated potassium channel activity. An important paralog of this gene is AKR7A3.

UniProtKB/Swiss-Prot: KCAB3_HUMAN, O43448
Function: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
Alters the functional properties of Kv1.5

summary for KCNAB3 Gene:
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the
Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming alpha-subunits
contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed
within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.

Gene Wiki entry for KCNAB3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010718.17  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCNAB3 gene promoter:
         c-Fos   Elk-1   AP-1   Sp1   NCX/Ncx   Tal-1beta   GATA-2   E47   c-Jun   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCNAB3 promoter sequence
   Search Chromatin IP Primers for KCNAB3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCNAB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

KCNAB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNAB3 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M007825:  view genomic region     (about GC identifiers)

Start:
7,825,177 bp from pter      End:
7,833,121 bp from pter
Size:
7,945 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KCAB3_HUMAN, O43448 (See protein sequence)
Recommended Name: Voltage-gated potassium channel subunit beta-3  
Size: 404 amino acids; 43670 Da
Subunit: Forms heteromultimeric complex with alpha subunits
Secondary accessions: Q4VAW0

Explore the universe of human proteins at neXtProt for KCNAB3: NX_O43448

Explore proteomics data for KCNAB3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KCNAB3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004723.2  
    ENSEMBL proteins: 
     ENSP00000302719   ENSP00000458237   ENSP00000461290  
    Reactome Protein details: O43448

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    antibodies-online proteins for KCNAB3 (3 products) 

     
    antibodies-online peptides for KCNAB3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    KCN: Potassium channels
    AKR: Aldo-keto reductases

    5 InterPro protein domains:
     IPR001395 Aldo/ket_red
     IPR023210 NADP_OxRdtase_dom
     IPR005399 K_chnl_volt-dep_bsu_KCNAB-rel
     IPR005402 K_chnl_volt-dep_bsu_KCNAB3
     IPR005983 K_chnl_volt-dep_bsu_KCNAB

    Graphical View of Domain Structure for InterPro Entry O43448

    ProtoNet protein and cluster: O43448

    2 Blocks protein domains:
    IPB001395 Aldo/keto reductase
    IPB005399 KCNAB voltage-gated K+ channel beta subunit family signature


    UniProtKB/Swiss-Prot: KCAB3_HUMAN, O43448
    Domain: Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit
    (Probable)
    Similarity: Belongs to the shaker potassium channel beta subunit family


    Find genes that share domains with KCNAB3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCAB3_HUMAN, O43448
    Function: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
    Alters the functional properties of Kv1.5

         Genatlas biochemistry entry for KCNAB3:
    potassium voltage-gated channel,Drosophila shaker-related subfamily,expressed in the brain and,predominantly in
    the cerebellum,auxiliary beta 3 cytoplasmic peptide,co assembly in the endoplasmic reticulum with the channel
    forming alpha subunits

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005249voltage-gated potassium channel activity IEA--
    GO:0015459potassium channel regulator activity TAS9857044
         
    Find genes that share ontologies with KCNAB3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KCNAB3:
     Increased Salmonella enterica  

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KCNAB3

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    hsa-miR-1206 hsa-miR-663 hsa-miR-3201 hsa-miR-1908 hsa-miR-1203 hsa-miR-744 hsa-miR-135b hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidKCNAB3 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KCAB3_HUMAN, O43448: Cytoplasm (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    cytosol2
    nucleus2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with KCNAB3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KCNAB3 About    
    See pathways by source

    SuperPathContained pathways About
    1Potassium Channels
    Potassium Channels0.43
    Voltage gated Potassium channels0.43
    2Transmission across Chemical Synapses
    Neuronal System0.68
    3Biological oxidations
    metapathway biotransformation0.42
    4Dopamine-DARPP32 Feedback onto cAMP Pathway
    Dopamine-DARPP32 Feedback onto cAMP Pathway


    Find genes that share SuperPaths with KCNAB3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for KCNAB3
        Dopamine-DARPP32 Feedback onto cAMP Pathway

    1 BioSystems Pathway for KCNAB3
        metapathway biotransformation

    1 Reactome Pathway for KCNAB3
        Voltage gated Potassium channels


        Pathway & Disease-focused RT2 Profiler PCR Array including KCNAB3: 
              Neuronal Ion Channels in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for KCNAB3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KCNAB3 (ENSP000003027194) via UniProtKB, MINT, STRING, and/or I2D (see all 51)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KCNA10ENSP000003587864STRING: ENSP00000358786
    KCNA5ENSP000002523214STRING: ENSP00000252321
    KCNA6ENSP000002806844STRING: ENSP00000280684
    KCNA7ENSP000002214444STRING: ENSP00000221444
    KCNAB2ENSP000001642474STRING: ENSP00000164247
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006813potassium ion transport TAS9857044
    GO:0007268synaptic transmission TAS--

    Find genes that share ontologies with KCNAB3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for KCNAB3 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    ICA 110381KV7.2/7.3 activator; displays anticonvulsant properties[325457-99-6]
    XE 991 dihydrochloride Potent, selective KV7 (KCNQ) channel blocker; blocks M-current [122955-42-4]
    JNJ 303Potent and selective IKs blocker[878489-28-2]
    E-4031 dihydrochlorideKV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)[113559-13-0]
    ShK-Dap22Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro[220384-25-8]



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KCNAB3 gene: 
    NM_004732.3  

    Unigene Cluster for KCNAB3:

    Potassium voltage-gated channel, shaker-related subfamily, beta member 3
    Hs.435074  [show with all ESTs]
    Unigene Representative Sequence: NM_004732
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000303790(uc002gjm.1) ENST00000572275 ENST00000570587(uc010vul.1)
    ENST00000576981 ENST00000574006 ENST00000570852
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    hsa-miR-1206 hsa-miR-663 hsa-miR-3201 hsa-miR-1908 hsa-miR-1203 hsa-miR-744 hsa-miR-135b hsa-miR-3119
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    Additional mRNA sequence: 

    AF016411.1 AK309378.1 AK309807.1 BC096232.1 BC096234.3 BC099634.1 

    4 DOTS entries:

    DT.65287315  DT.40255353  DT.40255364  DT.99933479 

    Selected AceView cDNA sequences (see all 384):

    BM662769 BQ949023 NM_004732 BM556844 CD676063 BM708261 BM788121 BM671855 
    CB136728 CD672530 BM694295 BQ649774 BU184836 AW517041 BU159194 T36039 
    AA167646 BU944766 H92563 AA324507 CA841706 CB243637 AA133344 BI767775 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for KCNAB3    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14
    SP1:        -     -                       -                                                                     
    SP2:                                                              -                                             
    SP3:                                      -                                                                     
    SP4:                                                                                                            


    ECgene alternative splicing isoforms for KCNAB3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KCNAB3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCTACTCGC
    KCNAB3 Expression
    About this image


    KCNAB3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Granulosa Cells Primary Follicle
     
     Eye (Sensory Organs)
     
     Spinal Cord (Nervous System)
    KCNAB3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCNAB3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.435074

    UniProtKB/Swiss-Prot: KCAB3_HUMAN, O43448
    Tissue specificity: Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex,
    occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney,
    pancreas, placenta and skeletal muscle

        Pathway & Disease-focused RT2 Profiler PCR Array including KCNAB3: 
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNAB3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KCNAB3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kcnab31 , 5 potassium voltage-gated channel, shaker-related subfamily, more1, 5 88.45(n)1
    93.07(a)1
      11 (42.51 cM)5
    164991  NM_010599.41  NP_034729.31 
     693262585 
    lizard
    (Anolis carolinensis)
    Reptilia KCNAB36
    potassium voltage-gated channel, shaker-related su...
    84(a)
    1 ↔ 1
    GL343784.1(12542-31422)
    African clawed frog
    (Xenopus laevis)
    Amphibia AF172145.12   -- 74.61(n)    AF172145.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003341581 voltage-gated potassium channel subunit beta-3-like 66(n)
    71.22(a)
      100334158  XM_002662191.3  XP_002662237.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hk3 potassium ion transport voltage-gated
    potassium more
    45(a)   1 9B5   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes --
    Putative aryl alcohol dehydrogenase; transcription...
    26(a)
    1 → many
    XVI(381965-382993) YPL088W


    ENSEMBL Gene Tree for KCNAB3 (if available)
    TreeFam Gene Tree for KCNAB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KCNAB3 gene
    AKR7A32  KCNAB12  AKR7L2  AKR7A22  KCNAB22  
    2 SIMAP similar genes for KCNAB3 using alignment to 3 protein entries:     KCAB3_HUMAN (see all proteins):
    KCNAB2    KCNAB1

    Find genes that share paralogs with KCNAB3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KCNAB3 (see all 211)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1811227701,2
    --7824799(+) GTTGGC/GTGCTA 1 -- ds50010--------
    rs750194671,2
    --7824854(+) GTTTTA/GCTTTG 1 -- ds50010--------
    rs1171550881,2
    F--7824863(+) TGCTTG/TCCCAG 1 -- ds50011Minor allele frequency- T:0.02NA 120
    rs124510771,2
    C,F,H--7825063(+) TACCTC/GTCCAC 1 -- ds500111Minor allele frequency- G:0.49NA WA CSA EA 374
    rs1439176091,2
    --7825070(+) CCACCA/GAATCA 1 -- ds50010--------
    rs1856603401,2
    --7825106(+) CTCCCA/CCTCAG 1 -- ds50010--------
    rs133415621,2
    C,F,A,H--7825117(+) CCACAG/AGTTCC 1 -- ds500114Minor allele frequency- A:0.03NS NA WA 1714
    rs1486223741,2
    --7825146(+) TCCAGC/TGAGAG 1 -- ds50010--------
    rs133415741,2
    C,F--7825332(+) GTCTTG/TGTCCT 1 -- ut31 ese34Minor allele frequency- T:0.07NA WA 242
    rs1420591981,2
    C--7825529(+) CAGTTA/GCCTGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for KCNAB3 (7825177 - 7833121 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for KCNAB3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670156CNV Deletion23128226
    nsv457660CNV Loss19166990
    nsv907654CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing KCNAB3
    DNA2.0 Custom Variant and Variant Library Synthesis for KCNAB3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604111    OMIM disorders: --


    Find genes that share disorders with KCNAB3           About GenesLikeMe


    Export disorders for KCNAB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KCNAB3 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with KCNAB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel. (PubMed id 9857044)1, 2, 3, 9 Leicher T.... Pongs O. (J. Biol. Chem. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    5. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (Cell 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)
    9. Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product. (PubMed id 7649300)1 Mccormack K.... Stuehmer W. (FEBS Lett. 1995)
    10. Time- and voltage-dependent modulation of a Kv1.4 channel by a beta-subunit (Kv beta 3) cloned from ferret ventricle. (PubMed id 7631872)9 Castellino R.C....Rasmusson R.L. (Am. J. Physiol. 1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9196 HGNC: 6230 AceView: KCNAB3andTRAPPC1 Ensembl:ENSG00000170049 euGenes: HUgn9196
    ECgene: KCNAB3 H-InvDB: KCNAB3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for KCNAB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KCNAB3 gene:
    Search GeneIP for patents involving KCNAB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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