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KCNA4 Gene

protein-coding   GIFtS: 63

GC11M029988
potassium voltage-gated channel, shaker-related subfamily, member 4
(Previous names: potassium voltage-gated channel, shaker-related subfamily, member 4-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: KCNA4L)
Services    

Aliases &
Descriptions
for KCNA4

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
HBK4 2, 3
HK1 1, 2, 3
HPCN2 1, 2, 3
HUKII 2, 3
KCNA4L 2, 3
KCNA8 2, 5
KV1.4 2
Kv1.4 1
PCN2 2
Descriptions
Voltage-gated potassium channel subunit Kv1.4 3
cardiac potassium channel 2
fetal skeletal muscle potassium channel 2
potassium channel 2 2
potassium voltage-gated channel, shaker-related subfamily,
member 4 2
potassium voltage-gated channel, shaker-related subfamily,
member 4-like 1, 2
rapidly inactivating potassium channel 2
shaker-related potassium channel Kv1.4 2
type A potassium channel 2
External Ids
HGNC: 62221
Entrez Gene: 37392
UniProtKB: P224593
Ensembl: ENSG000001822557
Search outside databases for aliases for KCNA4 gene

Previous GC identifers: GC11M031625 GC11M030806 GC11M030070 GC11M029996

Summaries
for KCNA4

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for KCNA4:
Potassium channels represent the most complex class of voltage-gated ion channels from both
functional and structural standpoints. Their diverse functions include regulating neurotransmitter
release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport,
smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes -
shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have
human homolog(s). This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type
repeat in the fourth segment. It belongs to the A-type potassium current class, the members of
which may be important in the regulation of the fast repolarizing phase of action potentials in
heart and thus may influnce the duration of cardiac action potential. The coding region of this
gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
[provided by RefSeq]

UniProtKB/Swiss-Prot: KCNA4_HUMAN, P22459
Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes.
Assuming opened or closed conformations in response to the voltage difference across the membrane,
the protein forms a potassium-selective channel through which potassium ions may pass in
accordance with their electrochemical gradient

Gene Wiki entry for KCNA4

Genomic Location
for KCNA4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the KCNA4 gene  

Entrez Gene cytogenetic band: 11p14   Ensembl cytogenetic band:  11p14.1   HGNC cytogenetic band: 11p14

KCNA4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M029988:     (about GC identifiers)

Start:
 29,988,341 bp from pter
End:
 29,995,064 bp from pter
Size:
 6,724 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000011.8  NT_009237.17  

Proteins
for KCNA4

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: KCNA4_HUMAN, P22459 (See protein sequence)
Recommended Name: Potassium voltage-gated channel subfamily A member 4  
Size: 653 amino acids; 73288 Da
Subunit: Heterotetramer of potassium channel proteins. Binds PDZ domains of DLG1, DLG2 and DLG4.
Interacts with OPRS1 (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_002224.1  

    ENSEMBL proteins: 
    ENSP00000328511 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant KCNA4 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Kv1.4)
    Human Recombinant Proteins from Abnova (KCNA4)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008076 voltage-gated potassium channel complex TAS2001794
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane IEA--
    About this table

    Antibodies for KCNA4: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of KCNA4
    Sigma-Aldrich Antibodies for KCNA4
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Kv1.4), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (KCNA4)
    Novus Biologicals Antibody for KCNA4

    Assays for KCNA4: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for KCNA4

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/8 InterPro domains/families (see all 8 ):
     IPR005821 Ion_trans
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003972 K_chnl_volt-dep_Kv1
     IPR012897 K_chnl_volt-dep_Kv1.4_TID


       GeneDecks  KCNA4 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P22459

    ProtoNet protein and cluster: P22459

    4 Blocks protein families:
    IPB000210 BTB/POZ domain
    IPB003091 Potassium channel signature
    IPB003972 Skaker voltage-gated K+ channel family signature
    IPB004051 Kv1.4 voltage-gated K+ channel signature


    UniProtKB/Swiss-Prot: KCNA4_HUMAN, P22459
    Domain: The N-terminus may be important in determining the rate of inactivation of the channel
    while the tail may play a role in modulation of channel activity and/or targeting of the channel
    to specific subcellular compartments
    Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of
    positively charged amino acids at every third position
    Similarity: Belongs to the potassium channel family. A (Shaker) subfamily

    Gene Function
    for KCNA4

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (KCNA4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (KCNA4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002233

                  Applied Biosystems Silencer® siRNAs for KCNA4

                  Sigma-Aldrich siRNA and siRNA Panels for KCNA4  
                         Sigma-Aldrich shRNA Panels and shRNA for KCNA4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Millipore Clones for the Expression of KCNA4
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002233
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002233
                                     untagged cDNA clone in CMV expression vector: NM_002233 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_002233

    UniProtKB/Swiss-Prot: KCNA4_HUMAN, P22459
    Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes.
    Assuming opened or closed conformations in response to the voltage difference across the membrane,
    the protein forms a potassium-selective channel through which potassium ions may pass in
    accordance with their electrochemical gradient

    Genatlas biochemistry entry for KCNA4:
    potassium voltage-gated channel,Drosophila shaker-related subfamily,member 4 (mouse Kv1.4 homolog)

    2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Kcna4):

    behavior/neurologicalnervous system

    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005244 voltage-gated ion channel activity IEA--
    GO:0005249 voltage-gated potassium channel activity TAS2001794
    GO:0005515 protein binding IPI9786987
    GO:0030955 potassium ion binding IEA--
    About this table

    Pathways & Interactions
    for KCNA4

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for KCNA4
      outward current

       GeneDecks  KCNA4 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  KCNA4 


    5/56 Interacting proteins for KCNA4 (ENSP000003285113 P224591, 2) via UniProtKB, MINT, and/or STRING (see all 56 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTN2P356092STRING (score=.759) MINT-14873 MINT-14874
    DLG4P783522STRING (score=.999) MINT-1901203 MINT-1900477
    Dlg4 Dlg4 (xeno)P310161, 2EBI-631235, EBI-375655 MINT-1900452 MINT-1901181
    NDUFA4L2Q9NRX32MINT-65617
    SAT1P216732MINT-63562
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811 ion transport IEA--
    GO:0006813 potassium ion transport TAS2001794
    About this table

    Drugs & Compounds
    for KCNA4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Compounds for KCNA4 available from Tocris Bioscience
    CompoundAction CAS number
    AM 92016 hydrochlorideKV channel blocker[178894-81-0]
    KN-93CaM kinase II inhibitor. Also K+ channel blocker (KV)[139298-40-1]
    SG 209K+ channel opener[83440-03-3]
    4-AminopyridineK+ channel blocker[504-24-5]
    About this table


    3 Novoseek chemical compound relationships for KCNA4 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    potassium 75.98 48 11598014 (2), 9867876 (2), 16837590 (2), 1900473 (1) (see all 36)
    calcium 30.52 7 16837590 (2), 10676964 (1), 11535596 (1), 11165788 (1) (see all 6)
    sodium 19.97 3 19118105 (1), 16546141 (1)
    About this table

    1 PharmGKB drug compound relationship for KCNA4 gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    antiarrhythmicsFA  GN  2001794
    About this table


    Transcripts
    for KCNA4

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (KCNA4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (KCNA4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002233

                  Sigma-Aldrich siRNA and siRNA Panels for KCNA4  
                         Sigma-Aldrich shRNA Panels and shRNA for KCNA4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_002233  

    REFSEQ mRNAs for KCNA4 gene: 

    NM_002233.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_002233  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002233
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002233
                                     untagged cDNA clone in CMV expression vector: NM_002233 

    Additional cDNA sequence: 

    AK311228.1 AK313662.1 L02751.1 M55514.1 M60450.1 

    2 DOTS entries:

    DT.306585  DT.120687017 

    20 AceView cDNA sequences:

    NM_002233 CF143509 BF196130 BF223341 L02751 BE467209 M60450 BX282390 
    AI631014 AI694934 BE467430 AI733207 AA974913 M55514 AI793138 AW275993 
    BE326268 BF111147 BX952248 AI701825 

    highest scoring ESTs for KCNA4:

    M55514 AI694934 BF196130 BX952248 AI631014 AI701825 AI733207 AI793138 AW275993 BE326268 

    Unigene Cluster for KCNA4:

    Potassium voltage-gated channel, shaker-related subfamily, member 4
    Hs.592002  [show with all ESTs]
    Unigene Representative Sequence: NM_002233


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000328224  

    Expression
    for KCNA4

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    KCNA4 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for KCNA4

    1 / 2 / 3

    3 probe-sets matching KCNA4 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		32344_r_at2, 3 U95-A 5 1.00 0.95 1.00 1.00 M55514 1.00 1.00 1.00 1

    		207248_at2, 3 U133-A 1 1.00 1.00 -- -- NM_002233 0.60 1.00 0.82 1

    		207248_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GCATAATTGT

    SOURCE GeneReport for Unigene cluster: Hs.592002

    Expression variation in blood from EXPOLDB for KCNA4

    Orthologs
    for KCNA4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for KCNA4 gene from 5/10 species (see all 10 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 KCNA41   -- potassium voltage-gated channel, shaker-related subfamily, more 83.31(n)
    89.71(a)    		 485427  XM_542545.2  XP_542545.2 
    chimpanzee
    (Pan troglodytes)    		 KCNA41   -- potassium voltage-gated channel, shaker-related subfamily, more 99.85(n)
    100(a)    		 466477  XM_521876.2  XP_521876.2 
    cow
    (Bos taurus)    		 KCNA41   -- potassium voltage-gated channel, shaker-related subfamily, more 89.83(n)
    96.47(a)    		 281880  NM_174371.2  NP_776796.1 
    rat
    (Rattus norvegicus)    		 Kcna41   -- potassium voltage-gated channel, shaker-related subfamily, more 90.61(n)
    97.24(a)    		 25469  NM_012971.1  NP_037103.1 
    mouse
    (Mus musculus)    		 Kcna41, 5 2 (61.00 cM)5
    		 potassium voltage-gated channel, shaker-related subfamily, more1, 5 91.07(n)1
    97.4(a)1    		 164921  NM_021275.31  NP_067250.21 
     AK0361125  BC1090145  (see all 8)
    About this table        Species with no ortholog for KCNA4

    ENSEMBL Gene Tree for KCNA4

    Paralogs
    for KCNA4

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for KCNA4 gene
    KCNA52  KCNA102  

    SNPs/Variants
    for KCNA4

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/37 NCBI SNPs in KCNA4 are shown (see all 37 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 37)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs122764751,2
    		H29989733(+) ATGGGG/TTGCTG 1 P/T mis1 ese34Minor allele frequency- T:0.00EU EA WA 404
    --
    rs108356091,2
    		A29996677(+) aaacaA/Cacaca 1 -- ng31 tfbs30--------
    rs38029141,2
    		A,C,F,H29989767(-) GCTGGC/TGGGCA 1 G/G syn14Minor allele frequency- T:0.15EU EA WA 420
    rs108356081,2
    		A,C,F,H29992753(+) CATGTC/TCCTTG 1 -- int14Minor allele frequency- T:0.44EU EA WA 420
    rs13238601,2
    		A,C,F,H29991812(-) TGAGTT/CACCAT 1 -- int16Minor allele frequency- C:0.41EU EA WA NA 602
    rs5343111,2
    		A,C,F29993358(-) GTTTTG/ATAAGT 1 -- int13Minor allele frequency- A:0.28EA NA 60
    --
    rs21948331,2
    		A,C29994656(+) AAGATA/CCaaaa 1 -- int10--------
    --
    rs341208611,2
    		--29996120(+) CTTTT-/ACGGGC 1 -- ng310--------
    --
    rs57907771,2
    		--29996612(+) aaaaa-/AGGGTT 1 -- ng31 trp30--------
    --
    rs719680511,2
    		--29996591(+) CATTT-/AAAAAA 1 -- ng310--------
    About this table

    HapMap Linkage Disequilibrium images for KCNA4 (up to first 250kb)

    Disorders & Mutations
    for KCNA4

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 176266

    1 Novoseek disease relationship for KCNA4 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    nasopharyngeal carcinoma 26.66 1 16142332 (1)
    About this table

    Medical News
    for KCNA4

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for KCNA4

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/87 PubMed articles for KCNA4 gene (see all 87 ):

    Search for KCNA4

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing KCNA4

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 3739 HGNC: 6222 AceView: KCNA4 Ensembl:ENSG00000182255 euGenes: HUgn3739
    ECgene: KCNA4 H-InvDB: KCNA4

    Other Databases showing KCNA4

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing KCNA4

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for KCNA4

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for KCNA4

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for KCNA4:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
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      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for KCNA4-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for KCNA4 Antibodies for KCNA4
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for KCNA4 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant Proteins
    (Kv1.4)
     Antibodies (Kv1.4)
     Search OriGene for KCNA4
     Tocris compounds for KCNA4




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for KCNA4

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