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KBTBD7 Gene

protein-coding   GIFtS: 51
GCID: GC13M041765

Kelch Repeat And BTB (POZ) Domain Containing 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kelch Repeat And BTB (POZ) Domain Containing 71 2
Kelch Repeat And BTB Domain-Containing Protein 72

External Ids:    HGNC: 252661   Entrez Gene: 840782   Ensembl: ENSG000001206967   UniProtKB: Q8WVZ93   

Export aliases for KBTBD7 gene to outside databases

Previous GC identifers: GC13M039563 GC13M040663 GC13M022565


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KBTBD7 Gene:
KBTBD7 (kelch repeat and BTB (POZ) domain containing 7) is a protein-coding gene. Diseases associated with KBTBD7 include huntington's disease, and hiv-1. An important paralog of this gene is KLHL21.

Gene Wiki entry for KBTBD7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NC_018924.2  NT_024524.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the KBTBD7 gene promoter:
         AhR   E2F-4   E2F-3a   E2F-5   E2F-2   LCR-F1   Tal-1beta   E2F   E2F-1   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKBTBD7 promoter sequence
   Search Chromatin IP Primers for KBTBD7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KBTBD7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.11   Ensembl cytogenetic band:  13q14.11   HGNC cytogenetic band: 13q13.3

KBTBD7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KBTBD7 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M041765:  view genomic region     (about GC identifiers)

Start:
41,763,969 bp from pter      End:
41,768,702 bp from pter
Size:
4,734 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KBTB7_HUMAN, Q8WVZ9 (See protein sequence)
Recommended Name: Kelch repeat and BTB domain-containing protein 7  
Size: 684 amino acids; 77163 Da
Secondary accessions: B5TZ86 Q5T6Y7 Q8NB99 Q9H0I6

Explore the universe of human proteins at neXtProt for KBTBD7: NX_Q8WVZ9

Explore proteomics data for KBTBD7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys187, Lys201, Lys263, Lys289, Lys403, Lys452, Lys511, Lys535
  • Modification sites at PhosphoSitePlus

  • See KBTBD7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115514.2  
    ENSEMBL proteins: 
     ENSP00000368797  

    KBTBD7 Human Recombinant Protein Products:

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    Novus Biologicals KBTBD7 Lysates
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    KBTBD7 Assay Products:

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    Cloud-Clone Corp. ELISAs for KBTBD7
    Cloud-Clone Corp. CLIAs for KBTBD7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing

    Selected InterPro protein domains (see all 7):
     IPR017096 Kelch-like_gigaxonin-typ
     IPR000210 BTB/POZ-like
     IPR006652 Kelch_1
     IPR011333 BTB/POZ_fold
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q8WVZ9

    ProtoNet protein and cluster: Q8WVZ9

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated


    UniProtKB/Swiss-Prot: KBTB7_HUMAN, Q8WVZ9
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 5 Kelch repeats


    KBTBD7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI16169070
         
    KBTBD7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KBTBD7:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KBTBD7
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KBTBD7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KBTBD7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KBTBD7

    miRNA
    Products:
        
    miRTarBase miRNAs that target KBTBD7:
    hsa-mir-877-3p (MIRT036875), hsa-mir-21-5p (MIRT030713)

    Block miRNA regulation of human, mouse, rat KBTBD7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KBTBD7 (see all 11):
    hsa-miR-576-5p hsa-miR-181c hsa-miR-4263 hsa-miR-944 hsa-miR-181a hsa-miR-181d hsa-miR-3662 hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidKBTBD7 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for KBTBD7
    Predesigned siRNA for gene silencing in human, mouse, rat KBTBD7

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: KBTBD7 (NM_032138)
    Sino Biological Human cDNA Clone for KBTBD7
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KBTBD7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KBTBD7

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for KBTBD7 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KBTBD7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    KBTBD7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including KBTBD7: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for KBTBD7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KBTBD7 (Q8WVZ91, 2, 3 ENSP000003687974) via UniProtKB, MINT, STRING, and/or I2D (see all 590)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    KBTBD7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KBTBD7 (KBTB7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KBTBD7 gene: 
    NM_032138.4  

    Unigene Cluster for KBTBD7:

    Kelch repeat and BTB (POZ) domain containing 7
    Hs.63841  [show with all ESTs]
    Unigene Representative Sequence: BC022033
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000379483(uc001uxw.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KBTBD7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KBTBD7 (see all 11):
    hsa-miR-576-5p hsa-miR-181c hsa-miR-4263 hsa-miR-944 hsa-miR-181a hsa-miR-181d hsa-miR-3662 hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidKBTBD7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KBTBD7
    Predesigned siRNA for gene silencing in human, mouse, rat KBTBD7
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KBTBD7
    Primer
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    OriGene qPCR primer pairs and template standards for KBTBD7
    OriGene qSTAR qPCR primer pairs in human, mouse for KBTBD7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KBTBD7
      QuantiTect SYBR Green Assays in human, mouse, rat KBTBD7
      QuantiFast Probe-based Assays in human, mouse, rat KBTBD7

    Additional mRNA sequence: 

    AK091344.1 AK299614.1 AK315589.1 AL136782.1 BC022033.2 CR533558.1 FJ150424.1 

    5 DOTS entries:

    DT.100738699  DT.210442  DT.100801329  DT.120794104  DT.40192958 

    Selected AceView cDNA sequences (see all 102):

    BF436101 AI312909 AI340297 AW572436 BU069965 BU070208 BF110230 AI631319 
    BC022033 BI491779 AI277867 CB158659 AI820566 AI819513 BF432075 Z41269 
    AA383657 AA334052 NM_032138 BF589011 BQ024653 AA376738 BF591650 AW955761 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KBTBD7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATCGACCT
    KBTBD7 Expression
    About this image


    KBTBD7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Eye (Sensory Organs)
             Retina
    KBTBD7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KBTBD7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.63841
        Pathway & Disease-focused RT2 Profiler PCR Array including KBTBD7: 
              Ubiquitin Ligases in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for KBTBD7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KBTBD7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KBTBD7 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kbtbd71 , 5 kelch repeat and BTB (POZ) domain containing 71, 5 88.87(n)1
    95.29(a)1
      14 (42.65 cM)5
    2112551  NM_001024135.21  NP_001019306.21 
     794265115 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.157102 Xenopus laevis transcribed sequence with weak similarity more 75.21(n)    BU906210.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kbtbd71 kelch repeat and BTB (POZ) domain containing 7 58.38(n)
    54(a)
      794299  XM_001334195.3  XP_001334231.1 


    ENSEMBL Gene Tree for KBTBD7 (if available)
    TreeFam Gene Tree for KBTBD7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KBTBD7 gene
    KLHL212  KLHL62  KBTBD82  KLHL412  KBTBD122  KBTBD22  KLHL242  ENC12  
    KLHL382  KLHL292  KBTBD32  KLHL232  KLHL402  KLHL302  KBTBD62  KLHL252  
    KLHL352  
    5 SIMAP similar genes for KBTBD7 using alignment to 2 protein entries:     KBTB7_HUMAN (see all proteins):
    KBTBD6    KLHL17    KBTBD3    KLHL20    KLHL32

    KBTBD7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KBTBD7 (see all 145)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1867503731,2
    --41765293(+) ATATTA/CCCTCA 1 -- int10--------
    rs1906494351,2
    --41765324(+) CACTTC/TCTGTT 1 -- int10--------
    rs581893071,2
    C,F--41765406(+) GACAAA/GTCATG 1 -- int14Minor allele frequency- G:0.07WA CSA EA 242
    rs95327391,2
    C,A,H--41765464(+) TTCCTC/TTGAGT 1 -- int1 ese34Minor allele frequency- T:0.00NS EA 420
    rs1833075031,2
    --41765489(+) TTGGGC/TATAAA 1 -- int10--------
    rs1407376161,2
    C--41765520(+) AGCAAA/GTTACC 1 -- int10--------
    rs1878013431,2
    --41765601(+) GATAGA/CAAATT 1 -- int10--------
    rs30720471,2
    C,A--41765688(+) TTTTTC/TTTTTT 1 -- int1 trp30--------
    rs1996881461,2
    --41765692(+) CTTTT-/TCTTTTT 1 -- int10--------
    rs170687261,2
    C,F,H--41765725(+) AGCTTA/GTGAGG 1 -- ut31 ese312Minor allele frequency- G:0.07NA NS WA CSA 1228

    HapMap Linkage Disequilibrium report for KBTBD7 (41763969 - 41768702 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KBTBD7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747299CNV Deletion23290073
    nsv832587CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KBTBD7
    DNA2.0 Custom Variant and Variant Library Synthesis for KBTBD7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for KBTBD7:    
    About MalaCards
    huntington's disease    hiv-1


    KBTBD7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KBTBD7
    Human Genome Epidemiology (HuGE) Navigator: KBTBD7 (1 document)

    Export disorders for KBTBD7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KBTBD7 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with KBTBD7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84078 HGNC: 25266 AceView: KBTBD7 Ensembl:ENSG00000120696 euGenes: HUgn84078
    ECgene: KBTBD7 H-InvDB: KBTBD7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KBTBD7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KBTBD7 gene:
    Search GeneIP for patents involving KBTBD7

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