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KAZALD1 Gene

protein-coding   GIFtS: 52
GCID: GC10P102810

Kazal-Type Serine Peptidase Inhibitor Domain 1

(Previous name: Kazal-type serine protease inhibitor domain 1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kazal-Type Serine Peptidase Inhibitor Domain 11 2     IGFBP-rP102
Kazal-Type Serine Protease Inhibitor Domain 11 2     Bone- And Odontoblast-Expressed Gene 12
BONO12     IGFBP-Related Protein 102
FKSG282     Kazal-Type Serine Protease Inhibitor Domain-Containing Protein 12
FKSG402     Novel Kazal-Type Serine Protease Inhibitor Domain And Immunoglobulin
Domain Containing Protein2

External Ids:    HGNC: 254601   Entrez Gene: 816212   Ensembl: ENSG000001078217   OMIM: 6092085   UniProtKB: Q96I823   

Export aliases for KAZALD1 gene to outside databases

Previous GC identifers: GC10P102487 GC10P096450


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KAZALD1 Gene:
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains
an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and
follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that
this gene product may have a function in bone development and bone regeneration. (provided by RefSeq, Feb 2009)

GeneCards Summary for KAZALD1 Gene:
KAZALD1 (Kazal-type serine peptidase inhibitor domain 1) is a protein-coding gene. Diseases associated with KAZALD1 include malignant peritoneal mesothelioma, and malignant pleural mesothelioma. GO annotations related to this gene include insulin-like growth factor binding. An important paralog of this gene is IGFBP7.

UniProtKB/Swiss-Prot: KAZD1_HUMAN, Q96I82
Function: Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes
matrix assembly (By similarity)

Gene Wiki entry for KAZALD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KAZALD1 gene promoter:
         NF-1/L   AML1a   Pax-5   Brachyury   CUTL1   MZF-1   CREB   deltaCREB   ARP-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKAZALD1 promoter sequence
   Search Chromatin IP Primers for KAZALD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KAZALD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.31   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24.32

KAZALD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KAZALD1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P102810:  view genomic region     (about GC identifiers)

Start:
102,820,999 bp from pter      End:
102,827,888 bp from pter
Size:
6,890 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: KAZD1_HUMAN, Q96I82 (See protein sequence)
Recommended Name: Kazal-type serine protease inhibitor domain-containing protein 1 precursor  
Size: 304 amino acids; 32945 Da
Secondary accessions: D3DR74 Q6ZMB1 Q9BQ73
Alternative splicing: 2 isoforms:  Q96I82-1   Q96I82-2   

Explore the universe of human proteins at neXtProt for KAZALD1: NX_Q96I82

Explore proteomics data for KAZALD1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn159, Asn183, Asn277

  • See KAZALD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112191.2  
    ENSEMBL proteins: 
     ENSP00000359219  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ISET: Immunoglobulin superfamily / I-set domain containing

    Selected InterPro protein domains (see all 8):
     IPR003598 Ig_sub2
     IPR002350 Kazal_dom
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR011390 IGFBP_rP_mac25

    Graphical View of Domain Structure for InterPro Entry Q96I82

    ProtoNet protein and cluster: Q96I82

    3 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB011497 Protease inhibitor
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: KAZD1_HUMAN, Q96I82
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 1 IGFBP N-terminal domain
    Similarity: Contains 1 Kazal-like domain


    KAZALD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KAZD1_HUMAN, Q96I82
    Function: Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes
    matrix assembly (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005520insulin-like growth factor binding IEA--
         
    KAZALD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KAZALD1:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Kazald1 (no phenotypes)

    KAZALD1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Kazald1tm1Lex for KAZALD1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KAZALD1
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    1 qRT-PCR Assays for microRNA that regulate KAZALD1:
    hsa-miR-335
    SwitchGear 3'UTR luciferase reporter plasmidKAZALD1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KAZD1_HUMAN, Q96I82: Secreted, extracellular space, extracellular matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    plasma membrane2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005614interstitial matrix IEA--
    GO:0031012extracellular matrix ----

    KAZALD1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KAZALD1
    Interactions:

        Search GeneGlobe Interaction Network for KAZALD1

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001503ossification IEA--
    GO:0001558regulation of cell growth IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--
    GO:0030198extracellular matrix organization IEA--

    KAZALD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for KAZALD1 (KAZD1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KAZALD1 gene: 
    NM_030929.4  

    Unigene Cluster for KAZALD1:

    Kazal-type serine peptidase inhibitor domain 1
    Hs.632079  [show with all ESTs]
    Unigene Representative Sequence: AK172864
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370200(uc001ksr.3 uc001kss.4 uc001kst.1) ENST00000477979
    ENST00000470106 ENST00000477267 ENST00000465807(uc001ksu.3) ENST00000608812


    miRNA
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    1 qRT-PCR Assays for microRNA that regulate KAZALD1:
    hsa-miR-335
    SwitchGear 3'UTR luciferase reporter plasmidKAZALD1 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat KAZALD1

    Additional mRNA sequence: 

    AK172862.1 AK172864.1 AK225949.1 AY359087.1 BC007758.2 

    6 DOTS entries:

    DT.95264894  DT.100000179  DT.121267200  DT.100020684  DT.92052860  DT.97839455 

    Selected AceView cDNA sequences (see all 75):

    AI658885 NM_030929 BG030637 BI766345 BC007758 BM976051 CA419201 BQ943656 
    BU619382 AK172862 BU734232 BQ017738 BC053611 BM709870 CA393819 CB105295 
    BF434771 BP357463 BQ015297 AY359087 AI620971 BI834297 BM919348 BF203282 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KAZALD1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c · 7d
    SP1:                                                                                      -     -                           
    SP2:                                            -                                                                           
    SP3:                                -     -     -                                         -     -                           
    SP4:                                                                                -     -     -                           
    SP5:                                -     -                                                                                 


    ECgene alternative splicing isoforms for KAZALD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KAZALD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KAZALD1 Expression
    About this image


    KAZALD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 6 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Mandibular Process
             HyStem+TGFbeta3+GDF5-induced 7SMOO32 cells
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Pre-Sertoli Cells Testis Cord
             Seminiferous Tubules
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+BMP4-induced E15 cells
    KAZALD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KAZALD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632079
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KAZALD1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kazald11 , 5 Kazal-type serine peptidase inhibitor domain 11, 5 85.45(n)1
    86.91(a)1
      19 (38.32 cM)5
    1072501  NM_178929.41  NP_849260.21 
     450752415 
    chicken
    (Gallus gallus)
    Aves KAZALD11 Kazal-type serine peptidase inhibitor domain 1 76.61(n)
    77.02(a)
      423856  XM_421724.4  XP_421724.1 
    lizard
    (Anolis carolinensis)
    Reptilia KAZALD16
    Kazal-type serine peptidase inhibitor domain 1
    63(a)
    1 ↔ 1
    GL343239.1(280271-296952)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.195902 Xenopus laevis transcribed sequence with weak similarity more 76.92(n)    BQ387731.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kazald31 Kazal-type serine peptidase inhibitor domain 3 57.99(n)
    53.88(a)
      100000101  NM_001123319.1  NP_001116791.1 


    ENSEMBL Gene Tree for KAZALD1 (if available)
    TreeFam Gene Tree for KAZALD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KAZALD1 gene
    IGFBP72  IGFBPL12  
    1 SIMAP similar gene for KAZALD1 using alignment to 1 protein entry:     KAZD1_HUMAN:
    IGFBP7

    KAZALD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KAZALD1 (see all 160)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1928834621,2
    --102819025(+) TGGGCC/TAATTT 1 -- us2k10--------
    rs8070391,2
    C,F,A,H--102819050(-) AACCCC/TGTCTC 1 -- us2k17Minor allele frequency- T:0.13NA WA CSA 15
    rs118129191,2
    C,F,H--102819064(+) ccataG/Ttgacc 1 -- us2k12Minor allele frequency- T:0.50NA CSA 6
    rs1845136891,2
    --102819183(+) AAAGAA/GACATG 1 -- us2k10--------
    rs1386287931,2
    --102819281(+) TCATCA/GTTCTG 1 -- us2k10--------
    rs1144418721,2
    C,F--102819332(+) TGAACG/ATATGA 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs1894492751,2
    --102819384(+) CATTCC/TATACC 1 -- us2k10--------
    rs575654891,2
    C--102819544(+) CTAGCA/CGTATT 1 -- us2k12Minor allele frequency- C:0.04WA 120
    rs1493318861,2
    --102819572(+) AAAATC/TCCTTC 1 -- us2k10--------
    rs107074051,2
    C--102819793(+) TTTAC-/GGTATG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KAZALD1 (102820999 - 102827888 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KAZALD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv895963CNV Loss21882294
    nsv831965CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KAZALD1
    DNA2.0 Custom Variant and Variant Library Synthesis for KAZALD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609208    OMIM disorders: --

    5 diseases for KAZALD1:    
    About MalaCards
    malignant peritoneal mesothelioma    malignant pleural mesothelioma    peritonitis    alzheimer's disease
    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for KAZALD1:
    Malignant peritoneal mesothelioma     Malignant pleural mesothelioma

    KAZALD1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): KAZALD1
    Human Genome Epidemiology (HuGE) Navigator: KAZALD1 (1 document)

    Export disorders for KAZALD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KAZALD1 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with KAZALD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    6. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    7. Bono1: a gene associated with regions of deposition of bone and dentine. (PubMed id 15261838)1, 9 James M.J....Thesleff I. (Gene Expr. Patterns 2004)
    8. Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma. (PubMed id 22836805)1 Hama R....Itoh F. (Tumour Biol. 2012)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells. (PubMed id 15555553)1 Shibata Y....Yamaguchi A. (Biochem. Biophys. Res. Commun. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81621 HGNC: 25460 AceView: KAZALD1 Ensembl:ENSG00000107821 euGenes: HUgn81621
    ECgene: KAZALD1 H-InvDB: KAZALD1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KAZALD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KAZALD1 gene:
    Search GeneIP for patents involving KAZALD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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