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Aliases for KATNBL1 Gene

Aliases for KATNBL1 Gene

  • Katanin Regulatory Subunit B1 Like 1 2 3 5
  • Katanin P80 Subunit B-Like 1 2 3 4
  • C15orf29 3 4
  • Chromosome 15 Open Reading Frame 29 2
  • KATNB1-Like Protein 1 3

External Ids for KATNBL1 Gene

Previous HGNC Symbols for KATNBL1 Gene

  • C15orf29

Previous GeneCards Identifiers for KATNBL1 Gene

  • GC15M034433

Summaries for KATNBL1 Gene

GeneCards Summary for KATNBL1 Gene

KATNBL1 (Katanin Regulatory Subunit B1 Like 1) is a Protein Coding gene.

Gene Wiki entry for KATNBL1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KATNBL1 Gene

Genomics for KATNBL1 Gene

Regulatory Elements for KATNBL1 Gene

Enhancers for KATNBL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F034182 1.2 Ensembl ENCODE 17.4 +26.9 26861 1.5 RFX1 ESRRA CEBPB SIN3A DPF2 REST GATA3 CTBP1 HSF1 ZBTB33 NOP10 KATNBL1 HNRNPLP2 AVEN AQR PIR44117
GH15F034055 0.8 Ensembl ENCODE 11.7 +153.6 153561 2.6 HDAC1 JUND JUN KDM1A HES1 AVEN KATNBL1 EMC4 GC15M034069 ENSG00000259505
GH15F034246 1.1 ENCODE 11.6 -36.6 -36619 1.4 CEBPB NOP10 SLC12A6 NUTM1 LPCAT4 KATNBL1 GOLGA8B ENSG00000259468 EMC4
GH15F034238 1.3 Ensembl ENCODE 11.6 -30.1 -30105 4.3 CTCF JUN TRIM22 REST EP300 RAD21 ZNF316 MAFF JUND STAT3 NOP10 KATNBL1 SLC12A6 NUTM1 ENSG00000259468 EMC4
GH15F034121 0.8 Ensembl ENCODE 11.6 +86.4 86397 4.4 PKNOX1 MTA2 NR2F1 ZBED1 BHLHE40 JUNB EBF1 TBX21 ATF2 EP300 EMC7 PGBD4 KATNBL1 NOP10 SLC12A6 GOLGA8B PIR44117
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around KATNBL1 on UCSC Golden Path with GeneCards custom track

Promoters for KATNBL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000020304 796 2201 HDGF ATF1 CREB3L1 ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 ELK1

Genomic Location for KATNBL1 Gene

Chromosome:
15
Start:
34,140,674 bp from pter
End:
34,210,096 bp from pter
Size:
69,423 bases
Orientation:
Minus strand

Genomic View for KATNBL1 Gene

Genes around KATNBL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KATNBL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KATNBL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KATNBL1 Gene

Proteins for KATNBL1 Gene

  • Protein details for KATNBL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H079-KTBL1_HUMAN
    Recommended name:
    KATNB1-like protein 1
    Protein Accession:
    Q9H079
    Secondary Accessions:
    • A8KAF6
    • Q2TAC0
    • Q9H670

    Protein attributes for KATNBL1 Gene

    Size:
    304 amino acids
    Molecular mass:
    34767 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15394.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for KATNBL1 Gene

Post-translational modifications for KATNBL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KATNBL1 Gene

Domains & Families for KATNBL1 Gene

Protein Domains for KATNBL1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KATNBL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KATNBL1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KATNBL1 Gene

Function for KATNBL1 Gene

Gene Ontology (GO) - Molecular Function for KATNBL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with KATNBL1: view
genes like me logo Genes that share phenotypes with KATNBL1: view

Animal Model Products

miRNA for KATNBL1 Gene

miRTarBase miRNAs that target KATNBL1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KATNBL1 Gene

Localization for KATNBL1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KATNBL1 Gene COMPARTMENTS Subcellular localization image for KATNBL1 gene
Compartment Confidence
nucleus 5
cytosol 1

Gene Ontology (GO) - Cellular Components for KATNBL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with KATNBL1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KATNBL1 Gene

Pathways & Interactions for KATNBL1 Gene

SuperPathways for KATNBL1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KATNBL1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KATNBL1 Gene

Transcripts for KATNBL1 Gene

Unigene Clusters for KATNBL1 Gene

Katanin p80 subunit B-like 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KATNBL1 Gene

No ASD Table

Relevant External Links for KATNBL1 Gene

GeneLoc Exon Structure for
KATNBL1
ECgene alternative splicing isoforms for
KATNBL1

Expression for KATNBL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KATNBL1 Gene

Protein differential expression in normal tissues from HIPED for KATNBL1 Gene

This gene is overexpressed in Bone (60.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KATNBL1 Gene



Protein tissue co-expression partners for KATNBL1 Gene

NURSA nuclear receptor signaling pathways regulating expression of KATNBL1 Gene:

KATNBL1

SOURCE GeneReport for Unigene cluster for KATNBL1 Gene:

Hs.633566
genes like me logo Genes that share expression patterns with KATNBL1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KATNBL1 Gene

Orthologs for KATNBL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KATNBL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KATNBL1 34 35
  • 100 (n)
dog
(Canis familiaris)
Mammalia KATNBL1 34 35
  • 94.52 (n)
cow
(Bos Taurus)
Mammalia KATNBL1 34 35
  • 93.64 (n)
rat
(Rattus norvegicus)
Mammalia Katnbl1 34
  • 89.52 (n)
mouse
(Mus musculus)
Mammalia Katnbl1 34 16 35
  • 88.85 (n)
oppossum
(Monodelphis domestica)
Mammalia KATNBL1 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KATNBL1 35
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H15ORF29 34 35
  • 79.84 (n)
lizard
(Anolis carolinensis)
Reptilia KATNBL1 35
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia katnbl1 34
  • 69.34 (n)
zebrafish
(Danio rerio)
Actinopterygii katnbl1 34 35
  • 56.8 (n)
wufc76b10 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2105 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6894 35
  • 38 (a)
OneToOne
Species where no ortholog for KATNBL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KATNBL1 Gene

ENSEMBL:
Gene Tree for KATNBL1 (if available)
TreeFam:
Gene Tree for KATNBL1 (if available)

Paralogs for KATNBL1 Gene

genes like me logo Genes that share paralogs with KATNBL1: view

No data available for Paralogs for KATNBL1 Gene

Variants for KATNBL1 Gene

Sequence variations from dbSNP and Humsavar for KATNBL1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10152261 -- 34,211,047(+) AAGGT(G/T)AGCCA upstream-variant-2KB
rs10152545 -- 34,183,059(+) ATGGC(A/G/T)CCCCT intron-variant
rs10152814 -- 34,183,199(+) TTGTT(G/T)GCTCC intron-variant
rs10524351 -- 34,177,644(+) AAAAA(-/AAAAAAAAAAA/AAAAAAAAAAAAA)GGATT intron-variant
rs1054671 -- 34,144,253(-) ATAAG(C/T)TCAGC intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for KATNBL1 Gene

Variant ID Type Subtype PubMed ID
dgv4456n54 CNV gain 21841781
dgv728e212 CNV loss 25503493
esv33337 CNV gain+loss 17666407
esv3569431 CNV gain 25503493
nsv1052620 CNV gain 25217958
nsv1125605 CNV tandem duplication 24896259

Variation tolerance for KATNBL1 Gene

Residual Variation Intolerance Score: 57.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.46; 43.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KATNBL1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KATNBL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KATNBL1 Gene

Disorders for KATNBL1 Gene

Relevant External Links for KATNBL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KATNBL1

No disorders were found for KATNBL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KATNBL1 Gene

Publications for KATNBL1 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64

Products for KATNBL1 Gene

Sources for KATNBL1 Gene

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