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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KATNAL1 Gene

protein-coding   GIFtS: 54
GCID: GC13M030776

Katanin P60 Subunit A-Like 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Katanin P60 Subunit A-Like 11 2 3
P60 Katanin-Like 12 3
EC 3.6.4.33 8
Katanin P60 ATPase-Containing Subunit A-Like 12

External Ids:    HGNC: 283611   Entrez Gene: 840562   Ensembl: ENSG000001027817   OMIM: 6147645   UniProtKB: Q9BW623   

Export aliases for KATNAL1 gene to outside databases

Previous GC identifers: GC13M028581 GC13M029680 GC13M011590


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KATNAL1 Gene: 
KATNAL1 (katanin p60 subunit A-like 1) is a protein-coding gene. Diseases associated with KATNAL1 include neuronitis. GO annotations related to this gene include ATP binding and microtubule-severing ATPase activity. An important paralog of this gene is VPS4B.

UniProtKB/Swiss-Prot: KATL1_HUMAN, Q9BW62
Function: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male
fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule
arrays (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  NC_018924.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KATNAL1 gene promoter:
         AREB6   PPAR-gamma1   POU2F1   SEF-1 (1)   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): KATNAL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for KATNAL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KATNAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.3   Ensembl cytogenetic band:  13q12.3   HGNC cytogenetic band: 13q12.3

KATNAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KATNAL1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M030776:  view genomic region     (about GC identifiers)

Start:
30,776,767 bp from pter      End:
30,881,621 bp from pter
Size:
104,855 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KATL1_HUMAN, Q9BW62 (See protein sequence)
Recommended Name: Katanin p60 ATPase-containing subunit A-like 1  
Size: 490 amino acids; 55392 Da
Subcellular location: Cytoplasm, cytoskeleton
Secondary accessions: A8K5X4

Explore the universe of human proteins at neXtProt for KATNAL1: NX_Q9BW62

Explore proteomics data for KATNAL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BW62

  • 4/20 DME Specific Peptides for KATNAL1 (Q9BW62) (see all 20)
     WDDIADL  KSVSAAD  RRLEKRI  QMDGVGG 

    KATNAL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KATNAL1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001014402.1  NP_115492.1  

    ENSEMBL proteins: 
     ENSP00000369989   ENSP00000369991   ENSP00000397776   ENSP00000407792  

    Human Recombinant Protein Products for KATNAL1: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KATNAL1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005874microtubule IEA--

    KATNAL1 for ontologies           About GeneDecksing



    KATNAL1 Antibody Products: 
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    Assay Products for KATNAL1: 
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    Cloud-Clone Corp. ELISAs for KATNAL1 
    Cloud-Clone Corp. CLIAs for KATNAL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    AATP: ATPases / AAA-type

    5 InterPro protein domains:
     IPR003959 ATPase_AAA_core
     IPR015415 Vps4_C
     IPR003960 ATPase_AAA_CS
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase

    Graphical View of Domain Structure for InterPro Entry Q9BW62

    ProtoNet protein and cluster: Q9BW62

    1 Blocks protein domain: IPB003960 AAA-protein subdomain

    UniProtKB/Swiss-Prot: KATL1_HUMAN, Q9BW62
    Similarity: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily


    KATNAL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KATL1_HUMAN, Q9BW62
    Function: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male
    fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule
    arrays (By similarity)
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Number (IUBMB): EC 3.6.4.31 2

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005524ATP binding IEA--
    GO:0008568microtubule-severing ATPase activity IEA--
    GO:0009378four-way junction helicase activity ----
    GO:0017111nucleoside-triphosphatase activity ----
         
    KATNAL1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KATNAL1:
     Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Katnal1):
     endocrine/exocrine gland  reproductive system 

    KATNAL1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KATNAL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KATNAL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KATNAL1 
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    miRNA
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    hsa-miR-3938 hsa-miR-19b-2* hsa-let-7d hsa-miR-429 hsa-miR-15a hsa-miR-200a hsa-miR-578 hsa-miR-29b-1*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KATNAL1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KATNAL1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for KATNAL1 (Q9BW622, 3 ENSP000003699894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COX17Q140612, 3, ENSP000002610704MINT-66362 I2D: score=5 STRING: ENSP00000261070
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    --ENSP000002685094STRING: ENSP00000268509
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair ----
    GO:0006310DNA recombination ----
    GO:0007283spermatogenesis IEA--
    GO:0051013microtubule severing IEA--

    KATNAL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KATNAL1 (KATL1)

    4 HMDB Compounds for KATNAL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    Search CenterWatch for drugs/clinical trials and news about KATNAL1 / KATL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KATNAL1 gene (2 alternative transcripts): 
    NM_001014380.2  NM_032116.4  

    Unigene Cluster for KATNAL1:

    Katanin p60 subunit A-like 1
    Hs.243596  [show with all ESTs]
    Unigene Representative Sequence: NM_032116
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380615(uc001uss.3 uc001ust.3) ENST00000380617 ENST00000480854
    ENST00000414289 ENST00000441394
    miRNA
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    8/50 QIAGEN miScript miRNA Assays for microRNAs that regulate KATNAL1 (see all 50):
    hsa-miR-3938 hsa-miR-19b-2* hsa-let-7d hsa-miR-429 hsa-miR-15a hsa-miR-200a hsa-miR-578 hsa-miR-29b-1*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KATNAL1
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): KATNAL1 (NM_032116)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KATNAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KATNAL1
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    Primer
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    OriGene qPCR primer pairs and template standards for KATNAL1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KATNAL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KATNAL1

    Additional mRNA sequence: 

    AK097423.1 AK291439.1 AK315724.1 BC000612.2 BX647147.1 

    4 DOTS entries:

    DT.40129064  DT.97798511  DT.70105251  DT.95157638 

    22 AceView cDNA sequences:

    AK097423 BU634530 NM_032116 BC000612 AL704125 AI809648 BG913072 BU568394 
    AI039250 BI462044 BQ772434 AI379588 AL702104 BE311939 BX954382 CD694916 
    BM152637 BU568862 AA284402 AA910028 CA419634 AA292530 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KATNAL1 expression in normal human tissues (normalized intensities)      KATNAL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATGATGGC
    KATNAL1 Expression
    About this image


    KATNAL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Lymph (Hematopoietic System)
             LYMPH NODE   

    See KATNAL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KATNAL1

    SOURCE GeneReport for Unigene cluster: Hs.243596

    UniProtKB/Swiss-Prot: KATL1_HUMAN, Q9BW62
    Tissue specificity: Expressed in testis, restricted to Sertoli cells (at protein level)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KATNAL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KATNAL1 gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Katnal11 , 5 katanin p60 subunit A-like 11, 5 85.66(n)1
    94.67(a)1
      5 (89.04 cM)5
    2319121  NM_153572.21  NP_705800.11 
     1488743325 
    chicken
    (Gallus gallus)
    Aves KATNAL11 katanin p60 subunit A-like 1 81.66(n)
    90.39(a)
      418920  XM_417114.3  XP_417114.1 
    lizard
    (Anolis carolinensis)
    Reptilia KATNAL16
    Uncharacterized protein
    88(a)
    1 ↔ 1
    3(184608312-184655858)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.185502 Transcribed sequence with weak similarity to protein more 72.59(n)    BM317123.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta katanin-601 katanin 60 57.34(n)
    60.96(a)
      53566  NM_080258.3  NP_524997.2 
    worm
    (Caenorhabditis elegans)
    Secernentea mei-16
    Meiotic spindle formation protein mei-1
    34(a)
    1 → many
    I(8294879-8296983)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS46
    AAA-ATPase involved in multivesicular body (MVB) p...
    34(a)
    1 → many
    XVI(886524-887837)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ERH31 Katanin p60 ATPase-containing subunit 55.37(n)
    54.34(a)
      844375  NM_106684.4  NP_178151.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06831001 hypothetical protein 56.6(n)
    55.62(a)
      4324404  NM_001050422.1  NP_001043887.1 


    ENSEMBL Gene Tree for KATNAL1 (if available)
    TreeFam Gene Tree for KATNAL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KATNAL1 gene
    VPS4B2  ENSG000002609142  KATNAL22  VPS4A2  KATNA12  
    8 SIMAP similar genes for KATNAL1 using alignment to 3 protein entries:     KATL1_HUMAN (see all proteins):
    KATNA1    VPS4A    VPS4B    KATNAL2    PSMC6    FIGNL1
    PSMC5    SPAST

    KATNAL1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2291 SNPs in KATNAL1 are shown (see all 2291)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1842396831,2
    --30776313(+) ATGTAA/CGATGT 2 -- ds50010--------
    rs740430571,2
    C,F--30776319(+) GATGTT/CAGTAA 2 -- ds50013Minor allele frequency- C:0.13WA CSA 122
    rs740430581,2
    C,F--30776459(+) ATAAAG/ATAAGA 2 -- ds50014Minor allele frequency- A:0.11WA CSA 123
    rs1889717221,2
    --30776515(+) TGGTGA/CTACAC 2 -- ds50010--------
    rs1821050271,2
    --30776686(+) CCTTAC/GTAGTG 2 -- ds50010--------
    rs1451849741,2
    --30776764(+) GAAAGC/TGATGA 2 -- ds50010--------
    rs1871339211,2
    --30776800(+) CCAAAC/TATAAC 2 -- ut310--------
    rs21499721,2
    H--30776952(-) GTTAAG/AACTTT 2 -- ut31 ese34Minor allele frequency- A:0.00NS EA 420
    rs104781,2
    C,F,A,H--30777202(-) ATACAA/GACTAA 2 -- ut31 ese325Minor allele frequency- G:0.36MN NS EA NA WA 2850
    rs1421483801,2
    C--30777227(+) GAAAAC/TAGATG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for KATNAL1 (30776767 - 30881621 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KATNAL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2657382CNV Deletion23128226
    nsv521987CNV Loss19592680
    nsv528192CNV Loss19592680
    nsv899962CNV Loss21882294
    nsv832572CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614764    OMIM disorders: --

    2 diseases for KATNAL1:    About MalaCards
    neuronitis    


    KATNAL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KATNAL1
    Human Genome Epidemiology (HuGE) Navigator: KATNAL1 (1 document)

    Export disorders for KATNAL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KATNAL1 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with KATNAL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    5. Genetically distinct subsets within ANCA-associated va sculitis. (PubMed id 22808956)1 Lyons P.A....Smith K.G. (2012)
    6. KATNAL1 regulation of Sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility. (PubMed id 22654668)2 Smith L.B.... Peters J. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV- infected men. (PubMed id 21897333)1 Irvin M.R....Arnett D.K. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. A genome-wide association study identifies a novel ma jor locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PubMed id 19875614)4 Paterson A.D....Bull S.B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84056 HGNC: 28361 AceView: KATNAL1 Ensembl:ENSG00000102781 euGenes: HUgn84056
    ECgene: KATNAL1 H-InvDB: KATNAL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KATNAL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KATNAL1 gene:
    Search GeneIP for patents involving KATNAL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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