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KATNA1 Gene

protein-coding GIFtS: 57

GC06M149957

katanin p60 (ATPase-containing) subunit A 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 3.6.4.3 ^³
OTTHUMP00000017392 ^²

Descriptions
Katanin p60 subunit A1 ^³
katanin p60 (ATPase-containing) subunit A 1 ^²
katanin p60 subunit A 1 ^²
p60 katanin ^³

External Ids
HGNC: 6216¹
Entrez Gene: 11104²
UniProtKB: O75449³
Ensembl: ENSG00000186625⁷

Search outside databases for aliases for KATNA1 gene

Previous GC identifers: GC06M149429 GC06M149763 GC06M9O0076

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KATNA1:

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing

cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that

consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1).

The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the

enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA

family of ATPases. [provided by RefSeq]

UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449

Function: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid

reorganization of cellular microtubule arrays, such as during disassembly of interphase

microtubules at the G2-M transition. May also be required for microtubule release from the

centrosome after nucleation. In mitotic spindles this could allow depolymerization of the

microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons,

microtubule release within the cell body may allow their subsequent transport into neuronal

processes by microtubule dependent motor proteins. This transport is required for axonal growth

(By similarity)

Gene Wiki entry for KATNA1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the KATNA1 gene

Entrez Gene cytogenetic band: 6q25.1 Ensembl cytogenetic band: 6q25.1 HGNC cytogenetic band: 6q24.3

KATNA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M149957: (about GC identifiers)

Start:	149,957,702 bp from pter
End:	150,011,543 bp from pter
Size:	53,842 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_025741.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449 (See protein sequence)

Recommended Name: Katanin p60 ATPase-containing subunit A1

Size: 491 amino acids; 55965 Da

Subunit: Can homooligomerize into hexameric rings, which may be promoted by interaction with

microtubules (By similarity). Interacts with KATNB1, which may serve as a targeting subunit

Subcellular location: Cytoplasm. Centrosome. Spindle. Note=Predominantly cytoplasmic. Also

localized to the interphase centrosome. Enhanced recruitment to the mitotic spindle poles requires

microtubules and interaction with KATNB1

Secondary accessions: Q5TFA8 Q5TFA9 Q86VN2 Q9NU52

Alternative splicing: 2 isoforms: O75449-1 O75449-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_008975.1

ENSEMBL proteins:

ENSP00000356381 ENSP00000335106 ENSP00000335180

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KATNA1)
	Human Recombinant Proteins from Abnova (KATNA1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000922	spindle pole	IDA	10751153
GO:0005737	cytoplasm	IEA	--
GO:0005813	centrosome	IEA	--
GO:0005874	microtubule	IEA	--

About this table

Antibodies for KATNA1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for KATNA1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (KATNA1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (KATNA1)
	Novus Biologicals Antibody for KATNA1

Assays for KATNA1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O75449

ProtoNet protein and cluster: O75449

1 Blocks protein family: IPB003960 AAA-protein subdomain

UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449

Domain: The N-terminus is sufficient for interaction with microtubules, although high affinity

binding requires an intact C-terminal domain and ATP, which promotes oligomerization (By

similarity)

Similarity: Belongs to the AAA ATPase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KATNA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KATNA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007044

Applied Biosystems Silencer® siRNAs for KATNA1

Sigma-Aldrich siRNA and siRNA Panels for KATNA1

Sigma-Aldrich shRNA for KATNA1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for KATNA1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_007044
Myc/DDK tagged cDNA clone in CMV expression vector: NM_007044
untagged cDNA clone in CMV expression vector: NM_007044

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_007044

UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449

Function: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid

reorganization of cellular microtubule arrays, such as during disassembly of interphase

microtubules at the G2-M transition. May also be required for microtubule release from the

centrosome after nucleation. In mitotic spindles this could allow depolymerization of the

microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons,

microtubule release within the cell body may allow their subsequent transport into neuronal

processes by microtubule dependent motor proteins. This transport is required for axonal growth

(By similarity)

Catalytic activity: ATP + H(2)O = ADP + phosphate

Enzyme regulation: ATPase activity is stimulated by microtubules, which promote homooligomerization

(By similarity). ATP dependent microtubule severing is stimulated by interaction with KATNB1

Enzyme Number (IUBMB): EC 3.6.4.3

1 MGI phenotypic allele for Katna1 (no phenotypes)

5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0008017	microtubule binding	IDA	10751153
GO:0008568	contributes to microtubule-severing ATPase activity	IDA	10751153
GO:0016787	hydrolase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for KATNA1 (Your Favorite Gene powered by Ingenuity)

Purine Metabolism

GeneDecks KATNA1 for the pathways selected above

About GeneDecksing

5 Interacting proteins for KATNA1 (ENSP00000356381³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KATNB1	ENSP00000368982³	STRING (score=.977)
DYNLT1	ENSP00000356056³	STRING (score=.899)
NDEL1	ENSP00000299734³	STRING (score=.899)
PAFAH1B1	ENSP00000006951³	STRING (score=.899)
--	ENSP00000351750³	STRING (score=.899)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007049	cell cycle	IEA	--
GO:0007067	mitosis	IEA	--
GO:0051301	cell division	IEA	--
GO:0051329	interphase of mitotic cell cycle	IMP	10751153

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for KATNA1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KATNA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KATNA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007044

Sigma-Aldrich siRNA and siRNA Panels for KATNA1

Sigma-Aldrich shRNA for KATNA1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_007044

REFSEQ mRNAs for KATNA1 gene:

NM_007044.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_007044

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_007044
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_007044
                                 untagged cDNA clone in CMV expression vector: NM_007044

Additional cDNA sequence:

AF056022.1 AK292090.1 BC050428.1 CR590166.1 CR600129.1 CR601101.1

12 DOTS entries:

DT.91739871 DT.95273610 DT.100783414 DT.100672584 DT.217838 DT.425072 DT.91739852 DT.95147814

DT.95273608 DT.95273609 DT.70103242 DT.99998659

24/144 AceView cDNA sequences (see all 144 ):

AA344883 AI873674 CR601101 CR600129 AI796400 AI268183 BI755443 AA281537

BG702518 AA913183 BU674288 AA137240 CA427490 AL525872 AA252346 CB243927

AI246235 BQ020488 CR619457 CA950724 BX102424 CB151916 CR590166 BC050428

highest scoring ESTs for KATNA1:

AF056022 AL543528 BC050428 BG390353 AA353514 AA403059 AA471300 AI191768 AL525872 AL701281

Unigene Cluster for KATNA1:

Katanin p60 (ATPase-containing) subunit A 1

Hs.450175 [show with all ESTs]

Unigene Representative Sequence: AK292090

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for KATNA1

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b
SP1:									-										-		-										-
SP2:									-
SP3:									-		-		-		-				-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for KATNA1

3 Ensembl transcripts including schematic representations:

ENST00000367411 ENST00000335647 ENST00000335643

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KATNA1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KATNA1

¹ / ² / ³

4 probe-sets matching KATNA1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32708_g_at²^{, 3}	U95-A	2	1.00	0.97	1.00	1.00	AI191768	0.60	1.00	0.82	1
32707_at²^{, 3}	U95-A	1	0.62	1.00	0.24	0.58	AI191768	0.60	1.00	0.82	1
205526_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_007044	0.60	1.00	0.82	1
205526_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TAAACTGTGA

SOURCE GeneReport for Unigene cluster: Hs.450175
Expression variation in blood from EXPOLDB for KATNA1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KATNA1 gene from 5/15 species (see all 15 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KATNA1¹	--	katanin p60 (ATPase-containing) subunit A 1	92.8(n) 97.35(a)	476240 XM_533445.2 XP_533445.1
chimpanzee (Pan troglodytes)	KATNA1¹	--	katanin p60 (ATPase-containing) subunit A 1	99.59(n) 99.8(a)	748379 XM_001173237.1 XP_001173237.1
cow (Bos taurus)	KATNA1¹	--	katanin p60 (ATPase-containing) subunit A 1	93.14(n) 97.15(a)	506715 XM_583196.3 XP_583196.2
rat (Rattus norvegicus)	Katna1¹	--	katanin p60 (ATPase-containing) subunit A1	89.21(n) 93.48(a)	292464 NM_001004217.2 NP_001004217.1
mouse (Mus musculus)	Katna1^{1, 5}	10⁵	katanin p60 (ATPase-containing) subunit A1^{1, 5}	88.66(n)¹ 93.08(a)¹	23924¹ NM_011835.1¹ NP_035965.1¹ AA958649⁵ AF153197⁵ (see all 10)

About this table Species with no ortholog for KATNA1

ENSEMBL Gene Tree for KATNA1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KATNA1 gene

KATNAL1² KATNAL2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/255 NCBI SNPs in KATNA1 are shown (see all 255 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 35)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs9027^1,2	A,C,F,H	149957750(-)	`TTTTTT/AAAAAA`	1	--	ng5¹		3	EA WA	260
	rs9689084^1,2	A,C,F,H	150002477(+)	`AAAAAA/GTTCCC`	1	--	ng3¹		4	EU EA WA	414
	rs7740278^1,2	A,C,F,H	150002945(+)	`agttaT/Cgctat`	1	--	ng3¹		4	EU EA WA	418
	rs9800580^1,2	A,C,F,H	149995674(+)	`CTGTCT/CAGTTT`	1	L/L	syn¹ ese³		4	EU EA WA	418
	rs2064520^1,2	A,C,F,H,O	149966479(+)	`TGTCAT/ACTCAT`	1	--	int¹		17	MN EU EA WA NA	1594
	rs9322193^1,2	A,C,F,H	149960836(+)	`CTGTGG/TGTGGC`	1	--	int¹		4	EU EA WA	416
	rs9766037^1,2	A,C,F,H	149979750(+)	`tcaacC/Aaatga`	1	--	int¹		8	EU EA WA	836
	rs3777949^1,2	A,C,F,H	149958850(-)	`AATGAT/CTGTGA`	1	--	int¹		12	EA EU WA NA	1704
	rs9322200^1,2	A,C,F,H	149992907(+)	`CACCTA/GCAACT`	1	--	int¹		4	EU EA WA	414
	rs9766886^1,2	A,C,F,H	149999877(+)	`AATTTC/TTGTTA`	1	--	int¹		4	EU EA WA	420

About this table

HapMap Linkage Disequilibrium images for KATNA1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606696

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/23 PubMed articles for KATNA1 gene (see all 23 ):

Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs. (PubMed id 9658175)^{2, 3, 4} McNally F.J. and Thomas S. (1998)
Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin. (PubMed id 10751153)^{1, 3, 4} McNally K.P.... McNally F.J. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis. (PubMed id 11870226)^{3, 4} Buster D.... McNally F.J. (2002)
LAPSER1/LZTS2: a pluripotent tumor suppressor linked to the inhibition of katanin-mediated microtubule severing. (PubMed id 18490357)³ Sudo H. and Maru Y. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Lipotransin: a novel docking protein for hormone-sensitive lipase. (PubMed id 10445032)³ Syu L.J. and Saltiel A.R. (1999)
An essential role for katanin in severing microtubules in the neuron. (PubMed id 10209026)³ Ahmad F.J....Baas P.W. (1999)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 11104	HGNC: 6216	AceView: KATNA1	Ensembl:ENSG00000186625	euGenes: HUgn11104
ECgene: KATNA1	H-InvDB: KATNA1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KATNA1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KATNA1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KATNA1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KATNA1		Antibodies for KATNA1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KATNA1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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KATNA1 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for KATNA1

Summaries
for KATNA1

Genomic Location
for KATNA1

Proteins
for KATNA1

Protein Domains/
Families
for KATNA1

Gene Function
for KATNA1

Pathways & Interactions
for KATNA1

Drugs & Compounds
for KATNA1

Transcripts
for KATNA1

Expression
for KATNA1

Orthologs
for KATNA1

Paralogs
for KATNA1

SNPs/Variants
for KATNA1

Disorders & Mutations
for KATNA1

Medical News
for KATNA1

Publications
for KATNA1

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Genome Databases showing KATNA1

Other Databases showing KATNA1

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Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KATNA1 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor KATNA1

Summariesfor KATNA1

Genomic Locationfor KATNA1

Proteinsfor KATNA1

Protein Domains/Familiesfor KATNA1

Gene Functionfor KATNA1

Pathways & Interactionsfor KATNA1

Drugs & Compoundsfor KATNA1

Transcriptsfor KATNA1

Expression for KATNA1

Orthologsfor KATNA1

Paralogsfor KATNA1

SNPs/Variantsfor KATNA1

Disorders & Mutationsfor KATNA1

Medical Newsfor KATNA1

Publicationsfor KATNA1

Search for KATNA1

Genome Databases showing KATNA1

Other Databases showing KATNA1

Specialized Databases showing KATNA1

Licensable Technologiesfor KATNA1

Servicesfor KATNA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KATNA1

Summaries
for KATNA1

Genomic Location
for KATNA1

Proteins
for KATNA1

Protein Domains/
Families
for KATNA1

Gene Function
for KATNA1

Pathways & Interactions
for KATNA1

Drugs & Compounds
for KATNA1

Transcripts
for KATNA1

Expression
for KATNA1

Orthologs
for KATNA1

Paralogs
for KATNA1

SNPs/Variants
for KATNA1

Disorders & Mutations
for KATNA1

Medical News
for KATNA1

Publications
for KATNA1

Licensable Technologies
for KATNA1

Services
for KATNA1