KATNA1 Gene
protein-coding GIFtS: 56
GCID: GC06M149957
|
|
katanin p60 (ATPase containing) subunit A 1(Previous name: katanin p60 (ATPase-containing) subunit A 1 )
| |
Aliases
for KATNA1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Katanin P60 (ATPase Containing) Subunit A 11 2 | | Katanin P60 (ATPase-Containing) Subunit A 11 2 | | Katanin P60 Subunit A12 3 | | P60 Katanin2 3 | | EC 3.6.4.33 8 | | Katanin P60 ATPase-Containing Subunit A12 |
Export aliases for KATNA1 gene to outside databasesPrevious GC identifers: GC06M149429 GC06M149763 GC06M9O0076 GC06M147482 |
Summaries
for KATNA1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KATNA1:
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help toorganize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemblemicrotubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. Thisprotein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein,have been identified. (provided by RefSeq, Feb 2011)
UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449Function: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing maypromote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosomefollowing nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubuleend proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubulerelease within the cell body of neurons may be required for their transport into neuronal processes bymicrotubule-dependent motor proteins. This transport is required for axonal growth (By similarity)
Gene Wiki entry for KATNA1
|
Genomic Views
for KATNA1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KATNA1 gene promoter:
Bach2 STAT5A Evi-1 HNF-1A POU2F1 POU2F1b HNF-1 POU2F1a POU2F1c
Other transcription factors
Search SABiosciences Chromatin IP Primers for KATNA1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KATNA1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q25.1 Ensembl cytogenetic band: 6q25.1 HGNC cytogenetic band: 6q24.3KATNA1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M149957: view genomic region
(about GC identifiers)
Start:
|
149,916,009 bp from pter |
End:
|
149,970,108 bp from pter |
Size:
|
54,100 bases |
Orientation:
|
minus strand |
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Proteins
for KATNA1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449 (See
protein sequence)Recommended Name: Katanin p60 ATPase-containing subunit A1 Size: 491 amino acids; 55965 Da
Subunit: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules (Bysimilarity). Interacts with KATNB1, which may serve as a targeting subunit. Interacts with dynein and NDEL1 (Bysimilarity). Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex).Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm,cytoskeleton, spindle pole. Midbody. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic. Localized diffusely inthe cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed thanthe microtubules. In anaphase and telophase is localized at the midbody region. Also localized to the interphasecentrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules andinteraction with KATNB1
Secondary accessions: E1P5A3 Q5TFA8 Q5TFA9 Q86VN2 Q9NU52Alternative splicing: 2 isoforms: O75449-1 O75449-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KATNA1: NX_O75449
Post-translational modifications:
Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation1
Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted to proteasomal degradation. Ubiquitinated by theBCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75449
4/18 DME Specific Peptides for KATNA1 (O75449) (see all 18)
KATNA1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001191005.1 NP_008975.1
ENSEMBL proteins: ENSP00000335106 ENSP00000335180 ENSP00000390322 ENSP00000398993 ENSP00000356381
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
KATNA1 for ontologies About GeneDecksing
KATNA1 Antibody Products:
Assay Products for KATNA1: |
Protein
Domains /
Families
for KATNA1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KATNA1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O75449ProtoNet protein and cluster: O75449 1 Blocks protein family: IPB003960 AAA-protein subdomain
UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449Domain: The N-terminus is sufficient for interaction with microtubules. However, high affinity binding to microtubulesalso requires an intact C-terminal domain and ATP, which promotes oligomerization (By similarity)Similarity: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily |
Function
for KATNA1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KTNA1_HUMAN, O75449Function: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing maypromote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosomefollowing nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubuleend proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubulerelease within the cell body of neurons may be required for their transport into neuronal processes bymicrotubule-dependent motor proteins. This transport is required for axonal growth (By similarity)Catalytic activity: ATP + H(2)O = ADP + phosphateEnzyme regulation: ATPase activity is stimulated by microtubules, which promote homooligomerization (By similarity).ATP dependent microtubule severing is stimulated by interaction with KATNB1Enzyme Number (IUBMB): EC 3.6.4.31 2
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KATNA1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KATNA1 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
KATNA1 for ontologies About GeneDecksing
Animal Models:
1 MGI phenotypic allele  for Katna1 (no phenotypes)
KATNA1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KATNA1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lissencephaly gene (LIS1) in neuronal migration and development | |
1  BioSystems Pathway for KATNA1
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KATNA1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/22 Interacting proteins for KATNA1 (O754493 ENSP000003351064) via UniProtKB, MINT, STRING, and/or I2D (see all 22)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
KATNA1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KATNA1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KATNA1
4 HMDB Compounds for KATNA1 About this table
Search CenterWatch for drugs/clinical trials and news about KATNA1 / KTNA1
|
Transcripts
for KATNA1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KATNA1 gene (2 alternative transcripts): NM_001204076.1 NM_007044.3 Unigene Cluster for KATNA1: Katanin p60 (ATPase containing) subunit A 1 Hs.450175 [show with all ESTs]Unigene Representative Sequence: NM_0070448 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000335647(uc003qmr.2) ENST00000335643(uc003qmt.3 uc011eed.1)
ENST00000494504 ENST00000481905 ENST00000470620 ENST00000444282 ENST00000420200
ENST00000367411(uc003qms.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KATNA1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KATNA1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KATNA1 (NM_007044) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KATNA1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KATNA1 |
Additional cDNA sequence: AF056022.1 AK292090.1 BC050428.1 11 DOTS entries: DT.91739871 DT.95273610 DT.217838 DT.91739852 DT.100672584 DT.95147814 DT.95273608 DT.95273609 DT.100783414 DT.425072 DT.99998659 24/144 AceView cDNA sequences (see all 144): CB151916 BX102424 BC050428 BI755443 AA344883 AA913183 AA252346 CB243927 BU674288 BG702518 BQ020488 AL525872 AA281537 CR619457 AA137240 AI246235 CR600129 AI873674 CA427490 CR590166 CR601101 AI268183 AI796400 CA950724
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for KATNA1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KATNA1
|
Expression
for KATNA1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KATNA1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAACTGTGA
About this image
See KATNA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KATNA1
SOURCE GeneReport for Unigene cluster: Hs.450175
SABiosciences Custom PCR Arrays for KATNA1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KATNA1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KATNA1 |
Orthologs
for KATNA1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KATNA1 gene from 7/30 species (see all 30) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KATNA11 |
katanin p60 (ATPase containing) subunit A 1 |
82.52(n)
88.98(a) |
|
421626 NM_001044648.1 NP_001038113.1 |
lizard
(Anolis carolinensis) |
Reptilia |
KATNA16 |
-- |
88(a) |
1 ↔ 1 |
GL343259.1(246590-257612) |
African clawed frog
(Xenopus laevis) |
Amphibia |
AF177942.12 |
-- |
79.33(n) |
|
AF177942.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
katna11 |
katanin p60 (ATPase-containing) subunit A 1 |
70.81(n)
78.47(a) |
|
553631 NM_001020604.1 NP_001018440.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
katanin-603 |
microtubule-based process microtubule
binding |
68(a)
(best of 4) |
|
82F6 -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
FTR6AT4G041806 |
AAA-type ATPase family protein |
46(a)15(a) |
1 ↔ manypossible ortholog |
1(30205315-30208226) 4(2020436-2023992) |
rice
(Oryza sativa) |
Liliopsida |
Os.269402 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
77.19(n) |
|
AK059564.1 |
ENSEMBL Gene Tree for KATNA1 (if available)
TreeFam Gene Tree for KATNA1 (if available) |
Paralogs
for KATNA1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KATNA1 gene
- VPS4B2 ENSG000002609142 KATNAL12 VPS4A2 KATNAL22
8 SIMAP similar genes for KATNA1 using alignment to 3 protein entries: KTNA1_HUMAN (see all proteins):KATNAL1 KATNAL2 VPS4A VPS4B FIGNL1 PSMC5
PSMC6 SPAST
KATNA1 for paralogs About GeneDecksing
|
Genomic Variants
for KATNA1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KATNA1 (149916009 - 149970108 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KATNA1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KATNA1 |
|
Disorders
/ Diseases
for KATNA1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KATNA1 for disorders About GeneDecksing
OMIM gene information: 606696
OMIM disorders: --
4  diseases for KATNA1: About MalaCardslissencephaly choriocarcinoma breast cancer neuronitis
Human Genome Epidemiology (HuGE) Navigator: KATNA1 (1 document)
Export disorders for KATNA1 gene to outside databases
|
Publications
for KATNA1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KATNA1 gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with KATNA1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs. (PubMed id 9658175)1, 2, 3 McNally F.J. and Thomas S. (1998)
- Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin. (PubMed id 10751153)1, 2, 9 McNally K.P.... McNally F.J. (2000)
- Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase. (PubMed id 19287380)1, 2, 9 Maddika S. and Chen J. (2009)
- The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells. (PubMed id 19261606)1, 2 Cummings C.M....Singer J.D. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis. (PubMed id 11870226)1, 2 Buster D.... McNally F.J. (2002)
- Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. (PubMed id 16203747)1, 9 Toyo-Oka K.... Hirotsune S. (2005)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Aberrant expression of katanin p60 in prostate cancer bone metastasis. (PubMed id 21681775)1 Ye X....Lin S.H. (2012)
|
External Searches for KATNA1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KATNA1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KATNA1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KATNA1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KATNA1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KATNA1 gene:
Search GeneIP for patents involving KATNA1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KATNA1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for KATNA1 | | OriGene shRNA RFP for KATNA1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KATNA1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KATNA1 | | | OriGene Protein Over-expression Lysate for KATNA1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KATNA1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KATNA1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KATNA1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KATNA1 | | OriGene Custom Protein Services for KATNA1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KATNA1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KATNA1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KATNA1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KATNA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KATNA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KATNA1 |
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| | | | Search Tocris compounds for KATNA1 |
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 | | | KATNA1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KATNA1 |
|  |  |  | | | | Search ThermoFisher Antibodies for KATNA1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KATNA1 |
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