KAT8 Gene
protein-coding GIFtS: 53
GCID: GC16P031130
|
|
K(lysine) acetyltransferase 8(Previous name: MYST histone acetyltransferase 1 )
(Previous symbol: MYST1)
| |
Aliases
for KAT8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| K(Lysine) Acetyltransferase 81 2 | | MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 12 3 | | MOF1 2 3 5 | | FLJ140401 | | MYST11 2 3 5 | | Histone Acetyltransferase KAT82 | | HMOF1 | | Histone Acetyltransferase MYST12 | | ZC2HC81 2 | | Ortholog Of Drosophila Males Absent On The First (MOF)2 | | MYST Histone Acetyltransferase 11 2 | | Probable Histone Acetyltransferase MYST12 | | Lysine Acetyltransferase 82 3 | | EC 2.3.1.483 | | MYST-12 3 | | |
Export aliases for KAT8 gene to outside databases |
Summaries
for KAT8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KAT8:
This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYSTdomain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-typezinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq, Feb 2012)
UniProtKB/Swiss-Prot: KAT8_HUMAN, Q9H7Z6Function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function ofATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specificallyH4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysineresidues. That activity is less specific than the one of the MSL complex
Gene Wiki entry for KAT8 (MYST1)
|
Genomic Views
for KAT8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for KAT8
Other transcription factors
Search SABiosciences Chromatin IP Primers for KAT8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KAT8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.1KAT8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P031130: view genomic region
(about GC identifiers)
Start:
|
31,127,075 bp from pter |
End:
|
31,142,714 bp from pter |
Size:
|
15,640 bases |
Orientation:
|
plus strand |
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Proteins
for KAT8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KAT8_HUMAN, Q9H7Z6 (See
protein sequence)Recommended Name: Histone acetyltransferase KAT8 Size: 458 amino acids; 52403 Da
Subunit: Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/KAT8,MSL1/hampin, MSL2L1 and MSL3L1. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3,MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. Component of some MLL1/MLL complex, at least composed of the core componentsMLL, ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1,LAS1L, MAX, MCRS1, MGA, MOF/KAT8, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6,TAF7, TAF9 and TEX10. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain.Interacts with KANSL1; the interaction is direct
Subcellular location: Nucleus. Chromosome (By similarity)
Sequence caution: Sequence=AAL55762.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;Sequence=AAL56648.1; Type=Frameshift; Positions=23, 26, 52;
6/7 PDB 3D structures from  and Proteopedia  for KAT8 (see all 7):2GIV (3D)
2PQ8 (3D)
2Y0M (3D)
3QAH (3D)
3TOA (3D)
3TOB (3D)
Secondary accessions: A8K4Z1 G5E9P2 Q659G0 Q7LC17 Q8IY59 Q8WYB4 Q8WZ14 Q9HAC5 Q9NR35Alternative splicing: 2 isoforms: Q9H7Z6-1 Q9H7Z6-2 (Ref.8 (CAH56416) sequence is in conflict in position: 454:M->I)Explore the universe of human proteins at neXtProt for KAT8: NX_Q9H7Z6
Post-translational modifications:
Autoacetylation at Lys-274 is required for proper function1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H7Z6
KAT8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_115564.2 NP_892003.2
ENSEMBL proteins: ENSP00000456933 ENSP00000219797 ENSP00000406037 ENSP00000454592
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
KAT8 for ontologies About GeneDecksing
KAT8 Antibody Products:
Assay Products for KAT8: |
Protein
Domains /
Families
for KAT8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KAT8 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H7Z6ProtoNet protein and cluster: Q9H7Z6 2 Blocks protein families: IPB000953 Chromo domain IPB002717 MOZ/SAS-like protein
UniProtKB/Swiss-Prot: KAT8_HUMAN, Q9H7Z6Similarity: Belongs to the MYST (SAS/MOZ) familySimilarity: Contains 1 C2HC-type zinc fingerSimilarity: Contains 1 chromo domain |
Function
for KAT8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KAT8_HUMAN, Q9H7Z6Function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function ofATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specificallyH4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysineresidues. That activity is less specific than the one of the MSL complexCatalytic activity: Acetyl-CoA + [histone] = CoA + acetyl-[histone]Enzyme Number (IUBMB): EC 2.3.1.481
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for KAT8 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KAT8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT8 |
Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10): About this table
KAT8 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for KAT8:
Animal Models:
Mouse knock-outs for KAT8: Kat8tm1.1Avo Kat8tm2Thl
6 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Kat8):
KAT8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KAT8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | p53 pathway | | | 2 | Signal transduction Activin A signaling regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KAT8
1  BioSystems Pathway for KAT8
KAT8 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KAT8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/106 Interacting proteins for KAT8 (Q9H7Z61, 2, 3 ENSP000004060374) via UniProtKB, MINT, STRING, and/or I2D (see all 106)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
KAT8 for ontologies About GeneDecksing
|
Drugs & Compounds
for KAT8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KAT8
Search CenterWatch for drugs/clinical trials and news about KAT8
|
Transcripts
for KAT8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KAT8 gene (2 alternative transcripts): NM_032188.2 NM_182958.2 Unigene Cluster for KAT8: K(lysine) acetyltransferase 8 Hs.533803 [show with all ESTs]Unigene Representative Sequence: AK2256607 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000543774 ENST00000219797(uc002eay.3) ENST00000448516(uc002eax.3)
ENST00000539683 ENST00000538768(uc002eaz.3) ENST00000537402(uc002eba.3)
ENST00000573144
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for KAT8 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KAT8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT8 |
Additional cDNA sequence: AF217501.1 AF260665.2 AK021872.1 AK024102.1 AK225660.1 AK291106.1 AL050395.1 BC037773.1 9 DOTS entries: DT.100815352 DT.455917 DT.100832888 DT.91994715 DT.120688821 DT.86848006 DT.120688827 DT.100025160 DT.100815353 24/154 AceView cDNA sequences (see all 154): BP342476 AJ713213 CA397719 BX339367 BF058490 CR625141 BQ670743 AW612043 F26568 CR596671 AU119306 BU844462 BE540486 CB157527 AI217074 AW517427 BQ641237 AI479441 CR596643 BI493073 AW961167 CK430874 AK024102 NM_032188
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for KAT8 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KAT8
|
Expression
for KAT8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KAT8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATATGAGA
About this image
See KAT8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KAT8
SOURCE GeneReport for Unigene cluster: Hs.533803
SABiosciences Expression via Pathway-Focused PCR Arrays including KAT8:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KAT8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KAT8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KAT8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KAT8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT8 |
Orthologs
for KAT8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KAT8 gene from 7/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
KAT86 |
-- |
82(a) |
1 ↔ 1 |
GL343220.1(2317592-2325172) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.192732 |
Xenopus laevis transcribed sequence with moderate similarity more |
85.39(n) |
|
48029594 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb22g022 |
Danio rerio cDNA clone MGC66387 IMAGE5777448, complete more |
78.13(n) |
|
BC055629.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
mof1 |
males absent on the first |
63.27(n)
58.46(a) |
|
31518 NM_078496.2 NP_511051.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
mys-21 |
Protein MYS-2 |
52.71(n)
48.48(a) |
|
173281 NM_061066.4 NP_493467.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
HAM11 |
histone acetyltransferase MYST1 |
57.44(n)
54.57(a) |
|
836582 NM_125857.2 NP_201266.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.98442 |
Oryza sativa (japonica cultivar-group) putative histone more |
73.74(n) |
|
NM_193033.1 |
ENSEMBL Gene Tree for KAT8 (if available)
TreeFam Gene Tree for KAT8 (if available) |
Paralogs
for KAT8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KAT8 gene
- KAT6B2 KAT72 KAT52 KAT6A2
7 SIMAP similar genes for KAT8 using alignment to 3 protein entries: KAT8_HUMAN (see all proteins):KAT5 DKFZp313G1618 KAT7 KAT6A KAT6B MYST3
MYST4
KAT8 for paralogs About GeneDecksing
|
Genomic Variants
for KAT8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KAT8 (31127075 - 31142714 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KAT8: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KAT8 |
|
Disorders
/ Diseases
for KAT8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KAT8 for disorders About GeneDecksing
OMIM gene information: 609912
OMIM disorders: --
6  diseases for KAT8: About MalaCardsmonocytic leukemia medulloblastoma breast carcinoma leukemia
immunodeficiency carcinoma
1 Novoseek disease relationship for KAT8 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| chromosomal aberrations |
41.9 |
3 |
17967868 (1) |
Export disorders for KAT8 gene to outside databases
|
Publications
for KAT8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KAT8 gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with KAT8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. (PubMed id 10786633)1, 2, 3 Neal K.C.... Lucchesi J.C. (2000)
- A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. (PubMed id 16227571)1, 2, 9 Smith E.R.... Lucchesi J.C. (2005)
- MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation. (PubMed id 12397079)1, 2, 9 Pardo P.S.... Pereira-Smith O.M. (2002)
- MYST protein acetyltransferase activity requires active site lysine autoacetylation. (PubMed id 22020126)1, 2 Yuan H....Marmorstein R. (2012)
- Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274. (PubMed id 21691301)1, 2 Sun B....Ding J. (2011)
- Subunit composition and substrate specificity of a MO F-containing histone acetyltransferase distinct from the male-specific lethal ( MSL) complex. (PubMed id 20018852)1, 2 Cai Y....Conaway R.C. (2010)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- Involvement of human MOF in ATM function. (PubMed id 15923642)1, 2 Gupta A.... Pandita T.K. (2005)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for KAT8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KAT8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KAT8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KAT8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KAT8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KAT8 gene:
Search GeneIP for patents involving KAT8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KAT8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for KAT8 | | OriGene shRNA RFP for KAT8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KAT8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KAT8 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KAT8 | | OriGene 3'-UTR Clone for KAT8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAT8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KAT8 | | OriGene Custom Protein Services for KAT8 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KAT8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KAT8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KAT8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KAT8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KAT8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KAT8 |
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| | | | Search Tocris compounds for KAT8 |
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 | | | KAT8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT8 |
|  |  |  | | | | ThermoFisher Antibody for KAT8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT8 |
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