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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KAT7 Gene

protein-coding   GIFtS: 53
GCID: GC17P047867

K(lysine) acetyltransferase 7

(Previous name: MYST histone acetyltransferase 2 )
(Previous symbol: MYST2)
 Explore 7 diseases affiliated with
KAT7 via our new
 Human Malady Compendium 
Biological research products
for KAT7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
K(Lysine) Acetyltransferase 71 2     Lysine Acetyltransferase 72 3
HBO11 2 3 5     MYST-22 3
MYST21 2 3 5     MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 22 3
HBOA1 2     Histone Acetyltransferase KAT72
ZC2HC71 2     Histone Acetyltransferase MYST22
MYST Histone Acetyltransferase 21 2     EC 2.3.1.483
Histone Acetyltransferase Binding To ORC12 3     HBOa3

External Ids:    HGNC: 170161   Entrez Gene: 111432   Ensembl: ENSG000001365047   OMIM: 6098805   UniProtKB: O952513   

Export aliases for KAT7 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: KAT7_HUMAN, O95251
Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it
may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses
AR-mediated transcription

Gene Wiki entry for KAT7 (MYST2)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KAT7
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKAT7 promoter sequence
   Search SABiosciences Chromatin IP Primers for KAT7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KAT7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.32   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.32

KAT7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KAT7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P047867:  view genomic region     (about GC identifiers)

Start:
47,865,917 bp from pter      End:
47,906,458 bp from pter
Size:
40,542 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KAT7_HUMAN, O95251 (See protein sequence)
Recommended Name: Histone acetyltransferase KAT7  
Size: 611 amino acids; 70642 Da
Subunit: Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and
PHF17. Interacts with MCM2 and ORC1L. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone
Subcellular location: Nucleus, nucleoplasm
Secondary accessions: B3KN74 B4DF85 B4DFB4 B4DFE0 B4DGY4 E7ER15 G5E9K7
Alternative splicing: 5 isoforms:  O95251-1   O95251-2   O95251-3   O95251-4   O95251-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KAT7: NX_O95251

Post-translational modifications:

  • Phosphorylation at Ser-57 by PLK1 during mitosis seems important for prereplicative complex formation and DNA
  • replication licensing, and requires prior Phosphorylation at Thr-85 and Thr-88 by CDK11
  • Autoacetylation at Lys-432 is required for proper function (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95251

  • KAT7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001186084.1  NP_001186085.1  NP_001186086.1  NP_001186087.1  NP_008998.1  

    ENSEMBL proteins: 
     ENSP00000259021   ENSP00000413415   ENSP00000424577   ENSP00000423385   ENSP00000398961  
     ENSP00000421368   ENSP00000409477   ENSP00000429939  

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    Uscn Proteins for KAT7

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA16387653
    GO:0005634nucleus ----
    GO:0005654nucleoplasm IDA16387653
    GO:0005730NOT nucleolus IDA16387653


    KAT7 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    KAT7 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR002515 Znf_C2HC
     IPR002717 MOZ_SAS
     IPR015880 Znf_C2H2-like
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry O95251

    ProtoNet protein and cluster: O95251

    1 Blocks protein family: IPB002717 MOZ/SAS-like protein

    UniProtKB/Swiss-Prot: KAT7_HUMAN, O95251
    Domain: The C2HC-type zinc finger is required for interaction with MCM2 and ORC1L
    Domain: The N-terminus is involved in transcriptional repression, while the C-terminus mediates AR-interaction (By
    similarity)
    Similarity: Belongs to the MYST (SAS/MOZ) family
    Similarity: Contains 1 C2HC-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: KAT7_HUMAN, O95251
    Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
    toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it
    may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses
    AR-mediated transcription
    Catalytic activity: Acetyl-CoA + [histone] = CoA + acetyl-[histone]

    Enzyme Number (IUBMB): EC 2.3.1.481

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0004402histone acetyltransferase activity IEA--
    GO:0005515protein binding IPI16189514
    GO:0008270zinc ion binding IEA--
    GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups ----


    KAT7 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for KAT7:
     Decreased POU5F1-GFP protein e  Decreased viability of wild-ty  Elongated cells  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-out Kat7tm1.2Avo for KAT7
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Kat7):
     cardiovascular system  cellular  craniofacial  embryogenesis  growth/size 
     mortality/aging 

    KAT7 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Androgen receptor signaling pathway
    Androgen receptor signaling pathway1.00
    2Regulation of Androgen receptor activity
    Regulation of Androgen receptor activity1.00
    3Signal transduction Activin A signaling regulation
    Histone modification0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for KAT7
        Histone modification


    2 BioSystems Pathways for KAT7 
        Androgen receptor signaling pathway
    Regulation of Androgen receptor activity



    KAT7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KAT7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/110 Interacting proteins for KAT7 (O952511, 2, 3 ENSP000002590214) via UniProtKB, MINT, STRING, and/or I2D (see all 110)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053, ENSP000003529804I2D: score=1 STRING: ENSP00000352980
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication IDA16387653
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent TAS10438470
    GO:0043966histone H3 acetylation IDA16387653
    GO:0043981histone H4-K5 acetylation IDA16387653


    KAT7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KAT7 gene (5 alternative transcripts): 
    NM_001199155.1  NM_001199156.1  NM_001199157.1  NM_001199158.1  NM_007067.4  

    Unigene Cluster for KAT7:

    K(lysine) acetyltransferase 7
    Hs.21907  [show with all ESTs]
    Unigene Representative Sequence: NM_007067
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000259021(uc002ipm.3 uc002ipl.2 uc010wma.2 uc010wmb.2 uc010wmc.2)
    ENST00000454930 ENST00000509773 ENST00000510819 ENST00000424009(uc010wmf.2 uc010wmg.2)
    ENST00000509124 ENST00000506533 ENST00000435742 ENST00000513171 ENST00000514540
    ENST00000513980 ENST00000512616 ENST00000508594 ENST00000509794 ENST00000510426
    ENST00000513075 ENST00000503101 ENST00000503635

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    hsa-miR-3607-3p hsa-miR-1914* hsa-miR-128 hsa-miR-134 hsa-miR-3142 hsa-miR-3150b-3p hsa-miR-149 hsa-miR-155*
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    Additional cDNA sequence: 

    AF074606.1 AF140360.1 AF217502.1 AK023890.1 AK293976.1 AK294014.1 AK294052.1 AK294367.1 
    AK294602.1 AK294836.1 AK295914.1 AK297212.1 BC015485.1 BC032640.2 

    21 DOTS entries:

    DT.95299807  DT.216516  DT.100026735  DT.100649914  DT.91771970  DT.91771972  DT.102830370  DT.99987631 
    DT.100654114  DT.100733282  DT.121300262  DT.91771965  DT.95208366  DT.100641942  DT.120954691  DT.120954714 
    DT.86852123  DT.91771967  DT.91771973  DT.95237644  DT.95293260 

    24/245 AceView cDNA sequences (see all 245):

    BM702762 AV709906 BQ058449 AA553564 AA828394 BP352458 BQ220366 BC032640 
    BX446886 BQ061070 AF217502 BM311497 AF074606 AA618583 BM552266 AA744725 
    AL039746 BQ888365 CA942695 AU125487 AA598797 AA322143 CB068380 BQ055533 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for KAT7 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b ·
    SP1:        -                                         -     -     -     -                                                     -     -                           
    SP2:                                                  -     -     -     -                                                     -     -                           
    SP3:                                                        -     -     -                                                                                       
    SP4:                                                                                                                                                            
    SP5:                                                                    -                                                                                       

    ExUns: 19c
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for KAT7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KAT7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCTCTGCTC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See KAT7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KAT7

    SOURCE GeneReport for Unigene cluster: Hs.21907

    UniProtKB/Swiss-Prot: KAT7_HUMAN, O95251
    Tissue specificity: Ubiquitously expressed, with highest levels in testis

        SABiosciences Expression via Pathway-Focused PCR Arrays including KAT7: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat
              Stem Cells in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KAT7 gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves MYST21 MYST histone acetyltransferase 2 83.63(n)
    97.87(a)
      425530  NM_001031341.1  NP_001026512.1 
    lizard
    (Anolis carolinensis)
    Reptilia KAT76
    --
    --
    95(a)
    14(a)
    1 ↔ 1
    possible ortholog
    6(76859588-76882811)
    GL343196.1(2273979-2316803)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC688692 hypothetical protein MGC68869 79.97(n)    BC059293.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.61072 Danio rerio mRNA similar to histone acetyltransferase more 77.68(n)    BC045314.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta chm1 chameau 50.03(n)
    48.69(a)
      43928  NM_135273.4  NP_609117.4 
    worm
    (Caenorhabditis elegans)
    Secernentea mys-46
    MYST family histone acetyltransferase-like family ...
    17(a)
    possible ortholog
    I(8333147-8336176)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons HAM26
    HAM16
    histone acetyltransferase MYST1
    38(a)
    36(a)
    many ↔ many
    many ↔ many
    5(3021952-3024756)
    5(25828160-25830524)
    rice
    (Oryza sativa)
    Liliopsida --
    MYST-like histone acetyltransferase 1, putative, e...
    36(a)
    1 → many
    7(25957775-25962658)


    ENSEMBL Gene Tree for KAT7 (if available)
    TreeFam Gene Tree for KAT7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KAT7 gene
    KAT6B2  KAT52  KAT82  KAT6A2  
    7 SIMAP similar genes for KAT7 using alignment to 4 protein entries:     KAT7_HUMAN (see all proteins):
    KAT6A    DKFZp313G1618    KAT5    MYST3    KAT8    KAT6B
    MYST4

    KAT7 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KAT7
    PGOHUM00000241454


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    9 NCBI SNPs in KAT7 are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1124014091,2
    C,--47866808(+) CAGGCCAGTTGCC
    TCCAAG
    /-
    CAGTT
    5 -- int11Minor allele frequency- -:0.50CSA 2
    rs346993261,2
    C,--47873414(+) TTGAA-/TTTTCC 1 -- int12Minor allele frequency- T:0.25NA CSA 4
    rs711469371,2
    C--47885483(+) TTTTT-/TGAGAC 1 -- int12Minor allele frequency- T:0.25NA 4
    rs361828371,2
    C,--47893781(+) TCTGA-/TATT  
            
    TATTT
    5 -- int10--------
    rs591722191,2
    C--47893783(+) ATTTA-/TTTA  
            
    GAGCT
    5 -- int11Minor allele frequency- TTTA:0.00NA 2
    rs572326621,2
    C--47896105(+) TCTTG-/TTTTTT 1 -- int12Minor allele frequency- T:0.25NA CSA 4
    rs711469391,2
    ----47897334(+) CATGG-/GCCAGG 1 -- int11Minor allele frequency- G:0.00NA 2
    rs2015718701,2
    ----47873414(+) TTGAAA/TTTTCC 1 -- int10--------
    rs354452811,2
    ----47877372(+) TGGCC-/TTTTTT 5 -- int10--------

    HapMap Linkage Disequilibrium report for KAT7 (47865917 - 47906458 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for KAT7: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    KAT7 for disorders           About GeneDecksing

    OMIM gene information: 609880    OMIM disorders: --

    7 diseases for KAT7:    About MalaCards
    monocytic leukemia    huntington's disease    breast cancer    leukemia
    immunodeficiency    thyroiditis    malaria


    Export disorders for KAT7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KAT7 gene, integrated from 9 sources (see all 56):
    (articles sorted by number of sources associating them with KAT7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Androgen receptor interacts with a novel MYST protein, HBO1. (PubMed id 10930412)1, 2, 3, 9 Sharma M....Sun Z. (2000)
    2. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. (PubMed id 10438470)1, 2, 3, 9 Iizuka M. and Stillman B. (1999)
    3. Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing. (PubMed id 18250300)1, 2 Wu Z.Q. and Liu X. (2008)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    5. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. (PubMed id 16387653)1, 2 Doyon Y.... Cote J. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. (PubMed id 11278932)1, 2 Burke T.W.... Nevins J.R. (2001)
    10. Ligand-controlled interaction of histone acetyltransferase binding to ORC-1 (HBO1) with the N-terminal transactivating domain of progesterone receptor induces steroid receptor coactivator 1-dependent coactivation of transcription. (PubMed id 16645042)1, 9 Georgiakaki M....Loosfelt H. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11143 HGNC: 17016 AceView: MYST2 Ensembl:ENSG00000136504 euGenes: HUgn11143
    ECgene: KAT7 H-InvDB: KAT7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KAT7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KAT7 gene:
    Search GeneIP for patents involving KAT7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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