Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



KAT2B Gene

protein-coding   GIFtS: 67
GCID: GC03P020081

K(Lysine) Acetyltransferase 2B

(Previous name: p300/CBP-associated factor)
(Previous symbol: PCAF)
  See KAT2B-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
K(Lysine) Acetyltransferase 2B1 2     P/CAF2 3
P300/CBP-Associated Factor1 2 3     EC 2.3.1.483 8
PCAF1 2 3     CAF2 5
Histone Acetylase PCAF2 3     P2
Histone Acetyltransferase PCAF2 3     CREBBP-Associated Factor2
Lysine Acetyltransferase 2B2 3     Histone Acetyltransferase KAT2B2

External Ids:    HGNC: 86381   Entrez Gene: 88502   Ensembl: ENSG000001141667   OMIM: 6023035   UniProtKB: Q928313   

Export aliases for KAT2B gene to outside databases

Previous GC identifers: GC03P020057 GC03P020021


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for KAT2B Gene:
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or
differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates
with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding
sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles,
indicating that this protein plays a direct role in transcriptional regulation. (provided by RefSeq, Jul 2008)

GeneCards Summary for KAT2B Gene:
KAT2B (K(lysine) acetyltransferase 2B) is a protein-coding gene. Diseases associated with KAT2B include enamel erosion, and holt-oram syndrome. GO annotations related to this gene include transcription coactivator activity and protein kinase binding. An important paralog of this gene is BAZ1A.

UniProtKB/Swiss-Prot: KAT2B_HUMAN, Q92831
Function: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant
histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also
acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic
activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat.
Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes

Gene Wiki entry for KAT2B (PCAF) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KAT2B gene promoter:
         c-Fos   AP-1   ATF-2   MyoD   STAT3   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKAT2B promoter sequence
   Search Chromatin IP Primers for KAT2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KAT2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p24   Ensembl cytogenetic band:  3p24.3   HGNC cytogenetic band: 3p24

KAT2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KAT2B gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P020081:  view genomic region     (about GC identifiers)

Start:
20,081,515 bp from pter      End:
20,195,896 bp from pter
Size:
114,382 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: KAT2B_HUMAN, Q92831 (See protein sequence)
Recommended Name: Histone acetyltransferase KAT2B  
Size: 832 amino acids; 93013 Da
Subunit: Interacts with SIRT1. Interacts (unsumoylated form) with NR2C1; the interaction promotes transactivation
activity (By similarity). Interacts with EP300, CREBBP and DDX17. Interacts with NCOA1 and NCOA3. Component of a
large chromatin remodeling complex, at least composed of MYSM1, KAT2B/PCAF, RBM10 and KIF11/TRIP5. Interacts with
NR2C2 (hypophosphorylated and unsumoylated form); the interaction promotes the transactivation activity of NR2C2.
Binds to HTLV-1 Tax. Interacts with and acetylates HIV-1 Tat. Interacts with KLF1; the interaction does not
acetylate KLF1 and there is no enhancement of its transactivational activity. Interacts with NFE4. Interacts with
MECOM. Interacts with E2F1; the interaction acetylates E2F1 augmenting its DNA-binding and transcriptional
activity
Selected PDB 3D structures from and Proteopedia for KAT2B (see all 9):
1CM0 (3D)        1JM4 (3D)        1N72 (3D)        1WUG (3D)        1WUM (3D)        1ZS5 (3D)    
Secondary accessions: Q6NSK1

Explore the universe of human proteins at neXtProt for KAT2B: NX_Q92831

Explore proteomics data for KAT2B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for KAT2B (Q92831)
     EQVKGYGT  YAIGYFKKQGF 


    See KAT2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003875.3  
    ENSEMBL proteins: 
     ENSP00000263754  
    Reactome Protein details: Q92831

    KAT2B Human Recombinant Protein Products:

    EMD Millipore Purified and/or Recombinant KAT2B Protein
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for KAT2B
    OriGene Purified Proteins for KAT2B
    OriGene Protein Over-expression Lysate for KAT2B
    OriGene MassSpec for KAT2B
    OriGene Custom Protein Services for KAT2B
    GenScript Custom Purified and Recombinant Proteins Services for KAT2B
    Novus Biologicals KAT2B Proteins
    Novus Biologicals KAT2B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KAT2B

     
    Search eBioscience for Proteins for KAT2B 

    KAT2B Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of KAT2B
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for KAT2B  (PCAF)
    OriGene Antibodies for KAT2B
    OriGene Custom Antibody Services for KAT2B
    Novus Biologicals KAT2B Antibodies
    Abcam antibodies for KAT2B
    Cloud-Clone Corp. Antibodies for KAT2B
    ThermoFisher Antibody for KAT2B
    LSBio Antibodies in human, mouse, rat for KAT2B

    KAT2B Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KAT2B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KAT2B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KAT2B
    Cloud-Clone Corp. CLIAs for KAT2B
    Search eBioscience for ELISAs for KAT2B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    KAT: Chromatin-modifying enzymes / K-acetyltransferases

    Selected InterPro protein domains (see all 6):
     IPR009464 PCAF_N
     IPR000182 GNAT_dom
     IPR018359 Bromodomain_CS
     IPR016376 Hist_acetylase_PCAF
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry Q92831

    ProtoNet protein and cluster: Q92831

    3 Blocks protein domains:
    IPB000182 GCN5-related N-acetyltransferase
    IPB001487 Bromodomain signature
    IPB009464 PCAF


    UniProtKB/Swiss-Prot: KAT2B_HUMAN, Q92831
    Domain: The bromodomain mediates binding to HIV-1 Tat
    Similarity: Belongs to the acetyltransferase family. GCN5 subfamily
    Similarity: Contains 1 bromo domain
    Similarity: Contains 1 N-acetyltransferase domain


    Find genes that share domains with KAT2B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KAT2B_HUMAN, Q92831
    Function: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant
    histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also
    acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic
    activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat.
    Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes
    Catalytic activity: Acetyl-CoA + [histone] = CoA + acetyl-[histone]

         Enzyme Number (IUBMB): EC 2.3.1.481 2

         Gene Ontology (GO): Selected molecular function terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003712transcription cofactor activity IPI8684459
    GO:0003713transcription coactivator activity IDA12435739
    GO:0004402histone acetyltransferase activity IEA--
    GO:0004468lysine N-acetyltransferase activity ISS--
    GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity ISS--
         
    Find genes that share ontologies with KAT2B           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Kat2b):
     embryogenesis  growth/size/body  mortality/aging  normal 

    Find genes that share phenotypes with KAT2B           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for KAT2B: Kat2btm1Nkt Kat2btm1Roth

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KAT2B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KAT2B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KAT2B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KAT2B

    miRNA
    Products:
        
    miRTarBase miRNAs that target KAT2B:
    hsa-mir-26b-5p (MIRT029198), hsa-mir-181a-5p (MIRT004327), hsa-mir-19a-3p (MIRT004334), hsa-mir-93-5p (MIRT004332), hsa-mir-92a-3p (MIRT004331), hsa-mir-19b-3p (MIRT004335), hsa-mir-32-5p (MIRT004330), hsa-mir-215-5p (MIRT024568), hsa-mir-25-3p (MIRT004329), hsa-mir-192-5p (MIRT026230), hsa-mir-106b-5p (MIRT004333), hsa-mir-181b-5p (MIRT004328)

    Block miRNA regulation of human, mouse, rat KAT2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KAT2B (see all 61):
    hsa-miR-140-5p hsa-miR-520e hsa-miR-302d hsa-miR-513a-5p hsa-miR-106a hsa-miR-25 hsa-miR-570 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidKAT2B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KAT2B
    Predesigned siRNA for gene silencing in human, mouse, rat KAT2B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KAT2B

    Clone
    Products:
         
    OriGene clones in human, mouse for KAT2B (see all 6)
    OriGene ORF clones in mouse, rat for KAT2B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KAT2B (NM_003884)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KAT2B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT2B
    Addgene plasmids for KAT2B 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KAT2B
    Browse ESI BIO Cell Lines and PureStem Progenitors for KAT2B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT2B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    KAT2B_HUMAN, Q92831: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton2
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex ----
    GO:0000125PCAF complex NAS17707232
    GO:0000776kinetochore IEA--
    GO:0005634nucleus ISS--
    GO:0005654nucleoplasm TAS--

    Find genes that share ontologies with KAT2B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for KAT2B About   (see all 28)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Notch signaling pathway (KEGG)
    Notch signaling pathway0.84
    Delta-Notch Signaling Pathway0.33
    Notch Signaling Pathway0.84
    2Signaling by NOTCH1 PEST Domain Mutants in Cancer
    Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants0.79
    Constitutive Signaling by NOTCH1 PEST Domain Mutants0.79
    Signaling by NOTCH1 PEST Domain Mutants in Cancer0.79
    Signaling by NOTCH1 t(7;9)(NOTCH1-M1580 K2555) Translocation Mutant0.79
    Signaling by NOTCH1 in Cancer0.79
    FBXW7 Mutants and NOTCH1 in Cancer0.79
    Signaling by NOTCH10.79
    NOTCH1 Intracellular Domain Regulates Transcription0.68
    3RNA Polymerase I Promoter Opening
    RNA Polymerase I Transcription0.78
    Chromatin modifying enzymes0.34
    RNA Polymerase I Promoter Clearance0.78
    HATs acetylate histones0.34
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.73
    Chromatin organization0.34
    4Pre-NOTCH Expression and Processing
    Pre-NOTCH Expression and Processing0.62
    Notch-HLH transcription pathway0.00
    Pre-NOTCH Transcription and Translation0.62
    5Development NOTCH1 mediated pathway for NF KB activity modulation
    Development NOTCH1 mediated pathway for NF KB activity modulation0.50
    Transcription Sin3 and NuRD in transcription regulation0.35
    Development Notch Signaling Pathway0.50


    Find genes that share SuperPaths with KAT2B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for KAT2B (see all 8)
        Nuclear Receptor Activation by Vitamin-A
    AMPK Enzyme Complex Pathway
    Protein Acetylation and Deacetylation
    Androgen Signaling
    p53 Signaling

    1 Cell Signaling Technology (CST) Pathway for KAT2B
        Chromatin Regulation / Acetylation

    Selected GeneGo (Thomson Reuters) Pathways for KAT2B (see all 8)
        Transcription Ligand-dependent activation of the ESR1/SP pathway
    Transcription P53 signaling pathway
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
    Development NOTCH1-mediated pathway for NF-KB activity modulation
    Transcription Sin3 and NuRD in transcription regulation

    Selected BioSystems Pathways for KAT2B (see all 12)
        Notch Signaling Pathway
    TGF-beta Receptor Signaling Pathway
    Androgen receptor signaling pathway
    Delta-Notch Signaling Pathway
    E2F transcription factor network

    Selected Reactome Pathways for KAT2B (see all 8)
        Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
    NOTCH1 Intracellular Domain Regulates Transcription
    HATs acetylate histones
    Notch-HLH transcription pathway
    YAP1- and WWTR1 (TAZ)-stimulated gene expression


    4 Kegg Pathways  (Kegg details for KAT2B):
        Notch signaling pathway
    Thyroid hormone signaling pathway
    HTLV-I infection
    Viral carcinogenesis

        Pathway & Disease-focused RT2 Profiler PCR Arrays including KAT2B: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat
              Mesenchymal Stem Cell in human mouse rat
              p53 Signaling Pathway in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for KAT2B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KAT2B (Q928311, 2, 3 ENSP000002637544) via UniProtKB, MINT, STRING, and/or I2D (see all 462)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BUB1BO605661, 2, 3, ENSP000002875984EBI-477430,EBI-1001438 MINT-7299990 MINT-7300008 MINT-7299777 MINT-7299740 MINT-7299797 MINT-7300223 MINT-7300201 MINT-7300263 MINT-7300283 MINT-7300181 MINT-7299749 MINT-7300243 MINT-7299763 I2D: score=2 STRING: ENSP00000287598
    HIST1H4AP628053, ENSP000003529804I2D: score=3 STRING: ENSP00000352980
    HIST1H4HP628053, ENSP000002893524I2D: score=3 STRING: ENSP00000289352
    HIST4H4P628053, ENSP000003507674I2D: score=3 STRING: ENSP00000350767
    HIST1H4FP628053, ENSP000003669744I2D: score=3 STRING: ENSP00000366974
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 23):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0006338chromatin remodeling NAS10365964
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006360transcription from RNA polymerase I promoter TAS--
    GO:0006361transcription initiation from RNA polymerase I promoter TAS--

    Find genes that share ontologies with KAT2B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KAT2B

    2 HMDB Compounds for KAT2B    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Coenzyme AAcetoacetyl coenzyme A sodium salt (see all 21)85-61-0--

    3 DrugBank Compounds for KAT2B    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE-- --target--10592235
    N-(3-AMINOPROPYL)-2-NITROBENZENAMINE-- --target--10592235
    Coenzyme A-- 85-61-0target----

    Selected Novoseek inferred chemical compound relationships for KAT2B gene (see all 12)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lysine 68 21 11931765 (4), 19351588 (2), 12486002 (2), 9891054 (2) (see all 14)
    polypropylene glycol 42 1 16862175 (1)
    acetyl-coa 35.3 11 9341171 (2), 15289617 (1), 10777508 (1)
    steroid 26.1 7 12790809 (1), 10453284 (1), 9296499 (1), 10845098 (1) (see all 6)
    retinoic acid 25.3 8 15489004 (4), 18443043 (1), 17389641 (1), 14980312 (1)
    curcumin 10.9 1 16787365 (1)
    estrogen 10.7 2 16309230 (1), 16152593 (1)
    lead 0 1 17444627 (1)
    progesterone 0 2 12790809 (1), 19609353 (1)
    zinc 0 6 18663001 (2), 12758070 (1), 12813456 (1), 11486036 (1)



    Find genes that share compounds with KAT2B           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for KAT2B gene: 
    NM_003884.4  

    Unigene Cluster for KAT2B:

    K(lysine) acetyltransferase 2B
    Hs.533055  [show with all ESTs]
    Unigene Representative Sequence: NM_003884
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263754(uc003cbq.3) ENST00000426228 ENST00000469085 ENST00000468111
    ENST00000468400
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KAT2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KAT2B (see all 61):
    hsa-miR-140-5p hsa-miR-520e hsa-miR-302d hsa-miR-513a-5p hsa-miR-106a hsa-miR-25 hsa-miR-570 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidKAT2B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KAT2B
    Predesigned siRNA for gene silencing in human, mouse, rat KAT2B
    Clone
    Products:
         
    OriGene clones in human, mouse for KAT2B (see all 6)
    OriGene ORF clones in mouse, rat for KAT2B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KAT2B (NM_003884)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KAT2B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT2B
    Addgene plasmids for KAT2B 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for KAT2B
    OriGene qSTAR qPCR primer pairs in human, mouse for KAT2B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KAT2B
      QuantiTect SYBR Green Assays in human, mouse, rat KAT2B
      QuantiFast Probe-based Assays in human, mouse, rat KAT2B

    Additional mRNA sequence: 

    AL832173.1 BC060823.1 BC070075.1 U57317.2 

    6 DOTS entries:

    DT.413547  DT.455550  DT.100817054  DT.120923372  DT.92441615  DT.95167340 

    Selected AceView cDNA sequences (see all 147):

    CR592587 BM721529 AW026794 AA932428 AW051871 T07150 AA643963 AI472591 
    BC060823 CA448582 AW192906 CD723514 AI473523 AA766914 AI749010 BU678653 
    BU154737 BU171918 AI359344 AL832173 BC070075 NM_003884 AI470982 BF196582 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for KAT2B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b ^ 18
    SP1:                                                  -           -                             -                             -                       -         
    SP2:                                                                                            -                                                               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for KAT2B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    KAT2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATACAGTTTG
    KAT2B Expression
    About this image


    KAT2B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    KAT2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KAT2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.533055

    UniProtKB/Swiss-Prot: KAT2B_HUMAN, Q92831
    Tissue specificity: Ubiquitously expressed but most abundant in heart and skeletal muscle

        Pathway & Disease-focused RT2 Profiler PCR Arrays including KAT2B: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat
              Mesenchymal Stem Cell in human mouse rat
              p53 Signaling Pathway in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for KAT2B
    OriGene qSTAR qPCR primer pairs in human, mouse for KAT2B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KAT2B
    QuantiTect SYBR Green Assays in human, mouse, rat KAT2B
    QuantiFast Probe-based Assays in human, mouse, rat KAT2B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT2B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KAT2B gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kat2b1 , 5 K(lysine) acetyltransferase 2B1, 5 88.64(n)1
    94.47(a)1
      17 (27.86 cM)5
    185191  NM_020005.41  NP_064389.21 
     535668615 
    chicken
    (Gallus gallus)
    Aves KAT2B1 K(lysine) acetyltransferase 2B 83.08(n)
    92.07(a)
      428441  XM_426001.4  XP_426001.4 
    lizard
    (Anolis carolinensis)
    Reptilia KAT2B6
    K(lysine) acetyltransferase 2B
    90(a)
    1 ↔ 1
    6(32865073-32894860)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kat2b1 K(lysine) acetyltransferase 2B 76.82(n)
    87.2(a)
      100488927  XM_002932406.2  XP_002932452.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kat2b1 K(lysine) acetyltransferase 2B 73.53(n)
    83.67(a)
      563942  NM_001045034.1  NP_001038499.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pcaf6
    Pcaf
    46(a)
    1 → many
    3L(12514229-12517114)
    worm
    (Caenorhabditis elegans)
    Secernentea pcaf-11 pcaf-1 47.38(n)
    37.21(a)
      171920  NM_058772.6  NP_491173.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GCN5(YGR252W)4
    GCN51
    Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay less4
    GCN51
    54.28(n)1
    49.56(a)1
      7(996869-998188)4
    8531671, 4  NP_011768.11, 4 


    ENSEMBL Gene Tree for KAT2B (if available)
    TreeFam Gene Tree for KAT2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for KAT2B gene
    BAZ1A2  BPTF2  BAZ2B2  CECR22  BAZ2A2  BAZ1B2  KAT2A2  
    1 SIMAP similar gene for KAT2B using alignment to 1 protein entry:     KAT2B_HUMAN:
    KAT2A

    Find genes that share paralogs with KAT2B           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for KAT2B
    PGOHUM00000249303


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for KAT2B (see all 2572)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1922914671,2
    --20079626(+) GTTCAC/GTTAAT 1 -- us2k10--------
    rs1384110871,2
    --20079741(+) ATTCTA/GAGGGA 1 -- us2k10--------
    rs1165465651,2
    C,F--20079800(+) CCTCCC/ACCAAT 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs1137836681,2
    C--20079805(+) CCAAT-/ATGTCA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1492470891,2
    --20079853(+) ATTGCA/GCACTG 1 -- us2k10--------
    rs750750071,2
    C,F--20079867(+) CCATTA/CCCTAG 1 -- us2k11Minor allele frequency- C:0.11WA 118
    rs126390781,2
    C,F,A,H--20079878(+) ACTCTA/GTTATA 1 -- us2k114Minor allele frequency- G:0.27NS EA EU NA WA 1108
    rs1393694171,2
    --20079984(+) CAAAGA/CGCACC 1 -- us2k10--------
    rs1432779311,2
    --20079994(+) CATTAC/GAGTTC 1 -- us2k10--------
    rs176269381,2
    C,F,H--20080132(+) TTAGTA/GTCTGT 1 -- us2k1 tfbs319Minor allele frequency- G:0.09NA NS EA WA 2546

    HapMap Linkage Disequilibrium report for KAT2B (20081515 - 20195896 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for KAT2B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422249CNV Deletion17116639
    esv267763CNV Insertion20981092
    nsv470450CNV Loss18288195
    nsv834627CNV Loss17160897
    nsv3719CNV Loss18451855
    nsv237514CNV Loss16902084
    esv35078CNV Gain17911159
    nsv433359CNV Gain18776910
    esv23068CNV Gain+Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KAT2B
    DNA2.0 Custom Variant and Variant Library Synthesis for KAT2B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602303    OMIM disorders: --

    2 diseases for KAT2B:    
    About MalaCards
    enamel erosion    holt-oram syndrome

    2 diseases from the University of Copenhagen DISEASES database for KAT2B:
    Enamel erosion     Plague

    Find genes that share disorders with KAT2B           About GenesLikeMe

    9 Novoseek inferred disease relationships for KAT2B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 3.38 2 17496784 (2)
    cancer 0.719 4 12402157 (2), 16638127 (1), 17725108 (1)
    leukemia 0 1 12878208 (1)
    virus infection 0 1 12743606 (1)
    glioma 0 1 10896202 (1)
    breast cancer 0 3 15009097 (1), 18089809 (1)
    tumors 0 21 10896202 (5), 17725108 (4), 15153330 (3), 17496784 (2) (see all 7)
    prostate cancer 0 1 17627840 (1)
    immunodeficiency 0 1 17444627 (1)

    Genetic Association Database (GAD): KAT2B
    Human Genome Epidemiology (HuGE) Navigator: KAT2B (7 documents)

    Export disorders for KAT2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for KAT2B gene, integrated from 10 sources (see all 407):
    (articles sorted by number of sources associating them with KAT2B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. (PubMed id 8684459)1, 2, 3 Yang X.-J.... Nakatani Y. (Nature 1996)
    2. Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF. (PubMed id 12486002)1, 2, 9 Bres V.... Kiernan R.E. (EMBO J. 2002)
    3. Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain. (PubMed id 11931765)1, 2, 9 Mujtaba S.... Zhou M.-M. (Mol. Cell 2002)
    4. The transcriptional coactivators p300 and CBP are histone acetyltransferases. (PubMed id 8945521)1, 2, 9 Ogryzko V.V.... Nakatani Y. (Cell 1996)
    5. Steroid receptor coactivator-1 is a histone acetyltransferase. (PubMed id 9296499)1, 2, 9 Spencer T.E....O'Malley B.W. (Nature 1997)
    6. Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women. (PubMed id 19950226)1, 4 Kontorovich T....Friedman E. (Int. J. Cancer 2010)
    7. Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF. (PubMed id 17226766)1, 2 Shin S. and Janknecht R. (J. Cell. Biochem. 2007)
    8. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. (PubMed id 17707232)1, 2 Zhu P.... Rosenfeld M.G. (Mol. Cell 2007)
    9. Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1. (PubMed id 15273251)1, 2 Zhao Q.... Jane S.M. (J. Biol. Chem. 2004)
    10. The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases. (PubMed id 14767476)1, 2 Gangisetty O.... Still I.H. (Oncogene 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 8850 HGNC: 8638 AceView: PCAF Ensembl:ENSG00000114166 euGenes: HUgn8850
    ECgene: KAT2B Kegg: 8850 H-InvDB: KAT2B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for KAT2B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for KAT2B gene:
    Search GeneIP for patents involving KAT2B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of KAT2B
     Browse Small Molecules at EMD Millipore
     EMD Millipore Purified and/or Recombinant KAT2B Protein
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for KAT2B   OriGene RNAi products in human, mouse, rat for KAT2B  
     OriGene qPCR primer pairs and template standards for KAT2B   OriGene Protein Over-expression Lysate for KAT2B  
     OriGene MassSpec something-or-other for KAT2B   OriGene clones in human, mouse for KAT2B  
     OriGene qSTAR qPCR primer pairs in human, mouse for KAT2B   OriGene Purified Protein for KAT2B  
     OriGene ORF clones in mouse, rat for KAT2B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KAT2B   OriGene Custom Protein Services for KAT2B  

     
     
     Block miRNA regulation of human, mouse, rat KAT2B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KAT2B
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KAT2B Predesigned siRNA for gene silencing in human, mouse, rat KAT2B
     QuantiFast Probe-based Assays in human, mouse, rat KAT2B QuantiTect SYBR Green Assays in human, mouse, rat KAT2B
     PCR Arrays including human, mouse, rat KAT2B Search Chromatin IP Primers for KAT2B
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KAT2B  GeneGlobe Interaction Network for KAT2B
     Regulatory tfbs in KAT2B promoter
     GenScript Custom Purified and Recombinant Proteins Services for KAT2B GenScript cDNA clones with any tag delivered in your preferred vector for KAT2B
     GenScript Custom Assay Services for KAT2B GenScript Custom overexpressing Cell Line Services for KAT2B
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Antibodies & Assays for KAT2B  (PCAF)

     Search Tocris compounds for KAT2B
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Proteins for KAT2B
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     KAT2B antibodies
     KAT2B proteins
     KAT2B lysates
     Antibodies for KAT2B
     See all of Abcam's Antibodies, Kits and Proteins for KAT2B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for KAT2B
     Antibodies for KAT2B
     ELISAs for KAT2B
     CLIAs for KAT2B



     Browse ESI BIO Cell Lines and PureStem Progenitors for KAT2B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAT2B
     SwitchGear 3'UTR luciferase reporter plasmids for KAT2B
     SwitchGear Promoter luciferase reporter plasmids for KAT2B
     ThermoFisher Antibody for KAT2B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAT2B
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KAT2B
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KAT2B
     LSBio Antibodies in human, mouse, rat for KAT2B
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Addgene plasmids for KAT2B
      Search eBioscience for proteins for KAT2B
      Search eBioscience for elisas for KAT2B
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KAT2B gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4