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KANSL3 Gene

protein-coding   GIFtS: 47
GCID: GC02M097259

KAT8 Regulatory NSL Complex Subunit 3

(Previous name: KIAA1310)
(Previous symbol: KIAA1310)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
KAT8 Regulatory NSL Complex Subunit 31 2     NSL32 3
KIAA13101 2 3     NSL Complex Protein NSL32 3
Non-Specific Lethal 3 Homolog2 3     Rcd12
Serum Inhibited-Related Protein2 3     PRTD3
Testis Development Protein PRTD2 3     SI13

External Ids:    HGNC: 254731   Entrez Gene: 556832   Ensembl: ENSG000001149827   UniProtKB: Q9P2N63   

Export aliases for KANSL3 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KANSL3 Gene:
KANSL3 (KAT8 regulatory NSL complex subunit 3) is a protein-coding gene. Diseases associated with KANSL3 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. GO annotations related to this gene include histone acetyltransferase activity (H4-K16 specific) and histone acetyltransferase activity (H4-K5 specific).

UniProtKB/Swiss-Prot: KANL3_HUMAN, Q9P2N6
Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
residues and therefore may be involved in the regulation of transcription

Gene Wiki entry for KANSL3 (FLJ10081) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for KANSL3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKANSL3 promoter sequence
   Search Chromatin IP Primers for KANSL3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KANSL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

KANSL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KANSL3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M097259:  view genomic region     (about GC identifiers)

Start:
97,258,907 bp from pter      End:
97,308,524 bp from pter
Size:
49,618 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: KANL3_HUMAN, Q9P2N6 (See protein sequence)
Recommended Name: KAT8 regulatory NSL complex subunit 3  
Size: 904 amino acids; 95992 Da
Subunit: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20,
OGT1/OGT, WDR5 and HCFC1
Sequence caution: Sequence=AAH15469.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAI27821.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of
unknown origin in the C-terminal part; Sequence=BAA92548.1; Type=Erroneous initiation; Note=Translation
N-terminally shortened;
Secondary accessions: A1L184 D3DXH3 D3DXH4 Q05BU4 Q6P3X2 Q6PJH6 Q86T19 Q96L64 Q9H0C9 Q9H8C9
Q9HAP8 Q9NWE5
Alternative splicing: 8 isoforms:  Q9P2N6-1   Q9P2N6-2   Q9P2N6-3   Q9P2N6-4   Q9P2N6-5   Q9P2N6-6   Q9P2N6-7   Q9P2N6-8   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KANSL3: NX_Q9P2N6

Explore proteomics data for KANSL3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KANSL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001108488.1  
    ENSEMBL proteins: 
     ENSP00000346144   ENSP00000394476   ENSP00000396749   ENSP00000414426   ENSP00000473116  
     ENSP00000415041   ENSP00000413229   ENSP00000397994   ENSP00000405988   ENSP00000415403  
     ENSP00000410775   ENSP00000415236   ENSP00000400678   ENSP00000469009   ENSP00000406207  
     ENSP00000407605  
    Reactome Protein details: Q9P2N6

    KANSL3 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026555 NSL3/Tex30

    Graphical View of Domain Structure for InterPro Entry Q9P2N6

    ProtoNet protein and cluster: Q9P2N6


    KANSL3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KANL3_HUMAN, Q9P2N6
    Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
    residues and therefore may be involved in the regulation of transcription

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043995contributes to histone acetyltransferase activity (H4-K5 specific) IDA--
    GO:0043996contributes to histone acetyltransferase activity (H4-K8 specific) IDA--
    GO:0046972contributes to histone acetyltransferase activity (H4-K16 specific) IDA--
         
    KANSL3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KANSL3
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    miRNA
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    miRTarBase miRNAs that target KANSL3:
    hsa-mir-16-5p (MIRT051184), hsa-mir-92a-3p (MIRT049440), hsa-mir-93-3p (MIRT038818), hsa-mir-484 (MIRT041753), hsa-mir-877-3p (MIRT036963), hsa-mir-26b-5p (MIRT030314)

    Block miRNA regulation of human, mouse, rat KANSL3 using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KANL3_HUMAN, Q9P2N6: Nucleus

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA--
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    KANSL3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KANSL3 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for KANSL3
        HATs acetylate histones



    KANSL3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KANSL3
    Interactions:

        Search GeneGlobe Interaction Network for KANSL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for KANSL3 (Q9P2N62, 3 ENSP000003967494) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MED10Q9BTT43, ENSP000002557644I2D: score=1 STRING: ENSP00000255764
    MED26O954023, ENSP000002633904I2D: score=1 STRING: ENSP00000263390
    RPS27AP629793, ENSP000002723174I2D: score=2 STRING: ENSP00000272317
    TFCP2L1Q9NZI63I2D: score=1 
    POLE4ENSP000004201764STRING: ENSP00000420176
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0043981histone H4-K5 acetylation IDA--
    GO:0043982histone H4-K8 acetylation IDA--
    GO:0043984histone H4-K16 acetylation IDA--

    KANSL3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KANSL3 (KANL3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KANSL3 gene (2 alternative transcripts): 
    NM_017991.4  NM_001115016.2  

    Unigene Cluster for KANSL3:

    KAT8 regulatory NSL complex subunit 3
    Hs.516341  [show with all ESTs]
    Unigene Representative Sequence: NR_047653
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000354204(uc002swi.4 uc002swp.1 uc002swk.4 uc002swn.4 uc010fhz.3 uc002swl.4 uc010yur.2)
    ENST00000447759(uc002swh.4) ENST00000487070(uc002swj.4) ENST00000431828
    ENST00000420155(uc002swm.4) ENST00000481986 ENST00000484020 ENST00000597150
    ENST00000444759(uc002swo.3) ENST00000476534 ENST00000488907 ENST00000425656(uc002swq.1)
    ENST00000452268 ENST00000448075 ENST00000451819 ENST00000416138 ENST00000418735
    ENST00000464738
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat KANSL3
      QuantiFast Probe-based Assays in human, mouse, rat KANSL3

    Additional mRNA sequence: 

    AB037731.1 AF117338.1 AF311326.1 AK000943.1 AK023813.1 AK074379.1 AK302646.1 AK304011.1 
    AK311617.1 AK314367.1 AY050169.1 BC015469.2 BC024276.1 BC032746.1 BC051763.1 BC063792.1 
    BC127820.1 NR_047653.1 NR_047654.1 NR_047655.1 NR_047656.1 NR_047657.1 NR_047658.1 

    Selected DOTS entries (see all 26):

    DT.95150592  DT.101984763  DT.447812  DT.97774641  DT.100797052  DT.100797053  DT.99991890  DT.100797061 
    DT.121024554  DT.121024584  DT.121024586  DT.99939579  DT.100797055  DT.101959698  DT.101965944  DT.121024547 
    DT.91765430  DT.75159474  DT.92024455  DT.99980899  DT.121024542  DT.121024564  DT.121024568  DT.121024569 

    Selected AceView cDNA sequences (see all 402):

    BP357092 AI168446 AA487210 BQ962384 BC063792 AI418804 AV659768 BF446771 
    AI937432 AA486848 AV699436 AI766177 BU183957 AA022619 AK091163 AI217880 
    BQ057298 BQ717323 CR602875 BE045531 AI968385 AK023813 AI263824 BE019330 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KANSL3 (see all 24)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b ·
    SP1:                          -     -     -     -           -     -     -                             -                                   -     -               
    SP2:                          -     -     -     -           -     -     -                             -                                   -     -               
    SP3:                          -     -     -     -           -     -     -     -                       -                                   -     -               
    SP4:                                                        -     -     -     -                       -                                   -     -               
    SP5:                                                                                                  -                                   -     -               

    ExUns: 11c ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21a · 21b ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27 ^ 28 ^ 29a ·
    SP1:                                                                    -                                   -                       -           -     -         
    SP2:                                                                    -                                   -                       -           -     -         
    SP3:                                                                                                        -           -     -     -           -     -         
    SP4:                                                                    -                                   -                       -           -     -         
    SP5:                                                                                                        -                       -           -     -         


    ECgene alternative splicing isoforms for KANSL3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KANSL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGATGCCCT
    KANSL3 Expression
    About this image

    KANSL3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KANSL3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.516341
        Custom PCR Arrays for KANSL3
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KANSL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KANSL3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kansl31 , 5 RIKEN cDNA 4632411B12 gene5
    KAT8 regulatory NSL complex subunit 31
    89.36(n)1
    94.53(a)1
      1 (15.22 cM)5
    2269761  NM_172652.31  NP_766240.11 
     363357305 
    chicken
    (Gallus gallus)
    Aves KANSL31 KAT8 regulatory NSL complex subunit 3 75.64(n)
    80.37(a)
      426585  XM_004947629.1  XP_004947686.1 
    lizard
    (Anolis carolinensis)
    Reptilia KANSL36
    KAT8 regulatory NSL complex subunit 3
    73(a)
    1 ↔ 1
    GL343608.1(233051-250888)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU909080.12   -- 76.17(n)    BU909080.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CD580634.12   -- 80.53(n)    CD580634.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rcd16
    Reduction in Cnn dots 1
    20(a)
    1 ↔ 1
    2R(10035768-10040624)
    worm
    (Caenorhabditis elegans)
    Secernentea F54D11.26
    Protein F54D11.2 (F54D11.2) mRNA, complete cds
    9(a)
    1 ↔ 1
    V(4617947-4628510) WBGene00018812


    ENSEMBL Gene Tree for KANSL3 (if available)
    TreeFam Gene Tree for KANSL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KANSL3 (see all 705)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs134058421,2
    C,F,H--97258451(+) AAAGGA/TAATTA 7 -- ds50018Minor allele frequency- T:0.14NS EA WA NA 780
    rs1380259891,2
    --97258515(+) GCGGGC/TGGATC 7 -- ds50010--------
    rs1834217271,2
    --97258613(+) CGGGCA/GCCTGT 7 -- ds50010--------
    rs1866864731,2
    --97258870(+) ACATAC/TGAGAA 7 -- ds50010--------
    rs1919913411,2
    --97258977(+) TCTATA/GACCCA 7 -- ut31 nc-transcript-variant0--------
    rs1835198931,2
    --97259036(+) CCTACC/TTCAGT 7 -- ut31 nc-transcript-variant0--------
    rs1490782351,2
    --97259134(+) TCTATC/TAATAA 7 -- ut31 nc-transcript-variant0--------
    rs1157484401,2
    C,F--97259221(+) GTTTGC/TGAAGG 7 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.02WA 118
    rs1431933861,2
    --97259263(+) ACTTCC/TTCTGT 7 -- ut31 nc-transcript-variant0--------
    rs1482681661,2
    C--97259318(+) CTTCTG/TCAGTT 7 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for KANSL3 (97258907 - 97308524 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KANSL3: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KANSL3
    DNA2.0 Custom Variant and Variant Library Synthesis for KANSL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for KANSL3:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    malaria


    KANSL3 for disorders           About GeneDecksing


    Export disorders for KANSL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KANSL3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with KANSL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. (PubMed id 20018852)1, 2 Cai Y.... Conaway R.C. (J. Biol. Chem. 2010)
    2. Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. (PubMed id 16543150)1, 2 Mendjan S.... Akhtar A. (Mol. Cell 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    6. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    10. Males absent on the first (MOF): from flies to humans. (PubMed id 17694080)1 Rea S....Akhtar A. (Oncogene 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55683 HGNC: 25473 AceView: FLJ10081 Ensembl:ENSG00000114982 euGenes: HUgn55683
    ECgene: KANSL3 H-InvDB: KANSL3

    (According to HUGE)
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    HUGE: KIAA1310

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KANSL3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KANSL3 gene:
    Search GeneIP for patents involving KANSL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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