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KANSL2 Gene

protein-coding   GIFtS: 49
GCID: GC12M049092

KAT8 Regulatory NSL Complex Subunit 2

(Previous name: chromosome 12 open reading frame 41)
(Previous symbol: C12orf41)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
KAT8 Regulatory NSL Complex Subunit 21 2
C12orf411 2 3 5
NSL22 3 5
Non-Specific Lethal 2 Homolog2 3
NSL Complex Protein NSL22 3
Chromosome 12 Open Reading Frame 411

External Ids:    HGNC: 260241   Entrez Gene: 549342   Ensembl: ENSG000001396207   OMIM: 6154885   UniProtKB: Q9H9L43   

Export aliases for KANSL2 gene to outside databases

Previous GC identifers: GC12M049056 GC12M049062 GC12M049069 GC12M049080


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KANSL2 Gene:
KANSL2 (KAT8 regulatory NSL complex subunit 2) is a protein-coding gene. Diseases associated with KANSL2 include malaria. GO annotations related to this gene include histone acetyltransferase activity (H4-K16 specific) and histone acetyltransferase activity (H4-K5 specific). An important paralog of this gene is INO80D.

UniProtKB/Swiss-Prot: KANL2_HUMAN, Q9H9L4
Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
residues and therefore may be involved in the regulation of transcription

Gene Wiki entry for KANSL2 (C12orf41) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_029419.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for KANSL2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for KANSL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KANSL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.11   Ensembl cytogenetic band:  12q13.11   HGNC cytogenetic band: 12q13.11

KANSL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KANSL2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M049092:  view genomic region     (about GC identifiers)

Start:
49,046,994 bp from pter      End:
49,076,035 bp from pter
Size:
29,042 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KANL2_HUMAN, Q9H9L4 (See protein sequence)
Recommended Name: KAT8 regulatory NSL complex subunit 2  
Size: 492 amino acids; 55042 Da
Subunit: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20,
OGT1/OGT, WDR5 and HCFC1
Sequence caution: Sequence=AAH09746.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH13900.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA91169.1;
Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAB14211.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=CAD39126.1; Type=Erroneous translation; Note=Wrong choice of
CDS;
Secondary accessions: Q8N3B5 Q96CV0 Q9NX51
Alternative splicing: 2 isoforms:  Q9H9L4-1   Q9H9L4-4   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for KANSL2: NX_Q9H9L4

Explore proteomics data for KANSL2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KANSL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060292.3  
    ENSEMBL proteins: 
     ENSP00000447093   ENSP00000448131   ENSP00000449747   ENSP00000415436   ENSP00000447608  
     ENSP00000449891   ENSP00000448833   ENSP00000449126   ENSP00000448129   ENSP00000448473  
     ENSP00000446493   ENSP00000350527  
    Reactome Protein details: Q9H9L4

    KANSL2 Human Recombinant Protein Products:

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    Novus Biologicals KANSL2 Lysate
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

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    KANSL2 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR025927 Potential_DNA-bd
     IPR026316 NSL2

    Graphical View of Domain Structure for InterPro Entry Q9H9L4

    ProtoNet protein and cluster: Q9H9L4


    KANSL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KANL2_HUMAN, Q9H9L4
    Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
    residues and therefore may be involved in the regulation of transcription

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043995contributes to histone acetyltransferase activity (H4-K5 specific) IDA--
    GO:0043996contributes to histone acetyltransferase activity (H4-K8 specific) IDA--
    GO:0046972contributes to histone acetyltransferase activity (H4-K16 specific) IDA--
         
    KANSL2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KANSL2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KANSL2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KANSL2

    miRNA
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    miRTarBase miRNAs that target KANSL2:
    hsa-mir-124-3p (MIRT023036), hsa-mir-34a-5p (MIRT047386), hsa-mir-92a-3p (MIRT049803)

    Block miRNA regulation of human, mouse, rat KANSL2 using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidKANSL2 3' UTR sequence
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    Predesigned siRNA for gene silencing in human, mouse, rat KANSL2

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KANSL2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KANSL2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KANL2_HUMAN, Q9H9L4: Nucleus

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA--
    GO:0005654nucleoplasm TAS--

    KANSL2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KANSL2 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for KANSL2
        HATs acetylate histones



    KANSL2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KANSL2
    Interactions:

        Search GeneGlobe Interaction Network for KANSL2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for KANSL2 (Q9H9L42, 3 ENSP000004154364) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MCRS1Q96EZ83I2D: score=6 
    MED28Q9H2043I2D: score=5 
    IKBKGENSP000003586224STRING: ENSP00000358622
    MED23ENSP000003570474STRING: ENSP00000357047
    --Q9WMX22MINT-7047502
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0043981histone H4-K5 acetylation IDA--
    GO:0043982histone H4-K8 acetylation IDA--
    GO:0043984histone H4-K16 acetylation IDA--

    KANSL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KANSL2 (KANL2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KANSL2 gene: 
    NM_017822.3  

    Unigene Cluster for KANSL2:

    KAT8 regulatory NSL complex subunit 2
    Hs.505412  [show with all ESTs]
    Unigene Representative Sequence: NM_017822
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000548147 ENST00000546701(uc001rry.2) ENST00000550347(uc001rrw.2 uc001rrz.2 uc001rrx.2)
    ENST00000420613 ENST00000549463 ENST00000548701 ENST00000547087 ENST00000549574
    ENST00000553086 ENST00000547582 ENST00000547536 ENST00000550931 ENST00000550870
    ENST00000548254 ENST00000548304 ENST00000357861
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KANSL2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate KANSL2
    SwitchGear 3'UTR luciferase reporter plasmidKANSL2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for KANSL2
    Predesigned siRNA for gene silencing in human, mouse, rat KANSL2
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    GenScript Custom all cDNA clones Services for KANSL2
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    Primer
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    OriGene qPCR primer pairs and template standards for KANSL2
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      QuantiTect SYBR Green Assays in human, mouse, rat KANSL2
      QuantiFast Probe-based Assays in human, mouse, rat KANSL2

    Additional mRNA sequence: 

    AK022732.1 AL834467.1 BC009746.2 BC013900.2 

    11 DOTS entries:

    DT.409230  DT.100776471  DT.100776469  DT.100776466  DT.95117603  DT.65286599  DT.100776468  DT.100684027 
    DT.97776335  DT.97816613  DT.97824603 

    18 AceView cDNA sequences:

    BC013900 CR617830 NM_017822 AL834467 BC009746 BM051376 CR606255 BX104898 
    CR616133 AK094528 AK000443 AK022732 BG315272 BQ322426 AW503587 BI038625 
    BQ304086 AW748091 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KANSL2 (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d · 15e ·
    SP1:              -     -                                                                 -     -     -                 -                                       
    SP2:                                                                                      -     -     -                 -                                       
    SP3:                                            -     -                                               -     -     -     -                                       
    SP4:                                                                                      -     -     -           -     -                                       
    SP5:              -     -           -                                                                                                                           

    ExUns: 15f
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for KANSL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KANSL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAGAAATC
    KANSL2 Expression
    About this image


    KANSL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)
             Bone Marrow
    KANSL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KANSL2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.505412
        Custom PCR Arrays for KANSL2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KANSL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KANSL2 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kansl21 , 5 RIKEN cDNA 2310037I24 gene5
    KAT8 regulatory NSL complex subunit 21
    89.64(n)1
    95.68(a)1
      15 (54.52 cM)5
    696121  NM_133714.41  NP_598475.21 
     985191015 
    chicken
    (Gallus gallus)
    Aves KANSL21 KAT8 regulatory NSL complex subunit 2 75.28(n)
    86.41(a)
      426401  XM_004950428.1  XP_004950485.1 
    lizard
    (Anolis carolinensis)
    Reptilia KANSL26
    KAT8 regulatory NSL complex subunit 2
    84(a)
    1 ↔ 1
    2(94569239-94588451)
    African clawed frog
    (Xenopus laevis)
    Amphibia flj20436-prov2 hypothetical protein MGC52525 76.5(n)    BC044061.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb75c022 wufb75c02 72.18(n)   322858  BG985686.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta dgt11 dim gamma-tubulin 1 47.57(n)
    42.41(a)
      43529  NM_143480.4  NP_651737.1 


    ENSEMBL Gene Tree for KANSL2 (if available)
    TreeFam Gene Tree for KANSL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KANSL2 gene
    INO80D2  

    KANSL2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KANSL2
    PGOHUM00000243279


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KANSL2 (see all 523)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs348797091,2
    C--48890741(+) TAGCC-/T/TT  
            
    TTTTT
    1 -- int10--------
    rs118381211,2
    C,F,H--49046526(+) TCTTAT/CAGAAA 1 -- int19Minor allele frequency- C:0.03NS EA NA CSA WA 616
    rs1822266931,2
    --49046648(+) CAAAAC/TGATCT 1 -- int10--------
    rs1129511761,2
    C,F--49046676(+) GTCTAC/TCTTAG 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs118350401,2
    C,F,H--49046768(+) TTTTTT/AAAAAA 1 -- int14Minor allele frequency- A:0.11NA WA 124
    rs118373371,2
    C,F,H--49046815(+) TCACCA/GCATTG 1 -- int111Minor allele frequency- G:0.03NS EA NA WA CSA 517
    rs1464811521,2
    --49046853(+) CAAGTA/GATCCG 1 -- int10--------
    rs786286651,2
    C,F--49046894(+) ACAGGC/TGTAAG 1 -- int11Minor allele frequency- T:0.07NA 120
    rs744516781,2
    C--49047001(+) TGGAAC/TTGATG 1 -- ut310--------
    rs1450527661,2
    C--49047121(+) ACTTCC/TCTTTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for KANSL2 (49046994 - 49076035 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KANSL2: --
    Human Gene Mutation Database (HGMD): KANSL2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KANSL2
    DNA2.0 Custom Variant and Variant Library Synthesis for KANSL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615488    OMIM disorders: --

    1 disease for KANSL2:    
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    malaria


    KANSL2 for disorders           About GeneDecksing


    Export disorders for KANSL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KANSL2 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with KANSL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. (PubMed id 20018852)1, 2 Cai Y.... Conaway R.C. (J. Biol. Chem. 2010)
    2. Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. (PubMed id 16543150)1, 2 Mendjan S.... Akhtar A. (Mol. Cell 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    10. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54934 HGNC: 26024 AceView: FLJ20436 Ensembl:ENSG00000139620 euGenes: HUgn54934
    ECgene: KANSL2 H-InvDB: KANSL2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KANSL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KANSL2 gene:
    Search GeneIP for patents involving KANSL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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