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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KANSL1 Gene

protein-coding   GIFtS: 50
GCID: GC17M044108

KAT8 Regulatory NSL Complex Subunit 1

(Previous name: KIAA1267)
(Previous symbol: KIAA1267)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
KAT8 Regulatory NSL Complex Subunit 11 2     MSL1 Homolog 12 3
KIAA12671 2 3 5     NSL Complex Protein NSL12 3
Centromere Protein 361 2     CENP-362
Non-Specific Lethal 1 Homolog2 3     KDVS2
NSL12 3     MSL1v12
hMSL1v12 3     Male-Specific Lethal 1 Homolog2
MLL1/MLL Complex Subunit KANSL12 3     MSL1V13

External Ids:    HGNC: 245651   Entrez Gene: 2840582   Ensembl: ENSG000001200717   OMIM: 6124525   UniProtKB: Q7Z3B33   

Export aliases for KANSL1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KANSL1 Gene:
This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation,
the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine)
acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. (provided by RefSeq, Jun 2012)

GeneCards Summary for KANSL1 Gene: 
KANSL1 (KAT8 regulatory NSL complex subunit 1) is a protein-coding gene. Diseases associated with KANSL1 include kansl1-related intellectual disability syndrome, and 17q21.31 microdeletion syndrome. GO annotations related to this gene include histone acetyltransferase activity (H4-K16 specific) and histone acetyltransferase activity (H4-K5 specific). An important paralog of this gene is KANSL1L.

UniProtKB/Swiss-Prot: KANL1_HUMAN, Q7Z3B3
Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
residues and therefore may be involved in the regulation of transcription

Gene Wiki entry for KANSL1 (KIAA1267) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NT_167251.1  NC_018928.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KANSL1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKANSL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for KANSL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KANSL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.31   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21.31

KANSL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KANSL1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M044108:  view genomic region     (about GC identifiers)

Start:
44,107,282 bp from pter      End:
44,302,740 bp from pter
Size:
195,459 bases      Orientation:
minus strand

1 alternative location:
Chr17+,NT_167251 563,498-759,135     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KANL1_HUMAN, Q7Z3B3 (See protein sequence)
Recommended Name: KAT8 regulatory NSL complex subunit 1  
Size: 1105 amino acids; 121025 Da
Subunit: Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1,
WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX,
MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9
and TEX10. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20,
OGT1/OGT, WDR5 and HCFC1. Interacts with KAT8; the interaction is direct
Subcellular location: Nucleus
Sequence caution: Sequence=CAH10565.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8K5E4 Q6AW85 Q8IYH1 Q9BRH0 Q9NTE7 Q9UFT0 Q9ULF3
Alternative splicing: 2 isoforms:  Q7Z3B3-1   Q7Z3B3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KANSL1: NX_Q7Z3B3

Explore proteomics data for KANSL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z3B3

  • KANSL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KANSL1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001180394.1  NP_001180395.1  NP_056258.1  

    ENSEMBL proteins: 
     ENSP00000461812   ENSP00000461299   ENSP00000461484   ENSP00000262419   ENSP00000459359  
     ENSP00000459330   ENSP00000459627   ENSP00000387393   ENSP00000377117  

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    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA--
    GO:0005634nucleus IDA--
    GO:0071339MLL1 complex IDA15960975

    KANSL1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026180 NSL1

    Graphical View of Domain Structure for InterPro Entry Q7Z3B3

    ProtoNet protein and cluster: Q7Z3B3


    KANSL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KANL1_HUMAN, Q7Z3B3
    Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine
    residues and therefore may be involved in the regulation of transcription

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
    GO:0043995contributes to histone acetyltransferase activity (H4-K5 specific) IDA--
    GO:0043996contributes to histone acetyltransferase activity (H4-K8 specific) IDA--
    GO:0046972contributes to histone acetyltransferase activity (H4-K16 specific) IDA--
         
    KANSL1 for ontologies           About GeneDecksing


    Phenotypes:
         5 GenomeRNAi human phenotypes for KANSL1:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Increased gamma-H2AX phosphory 
     Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Kansl1):
     behavior/neurological  nervous system  other 

    KANSL1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KANSL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KANSL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KANSL1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KANSL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/600 Interacting proteins for KANSL1 (Q7Z3B31, 2, 3 ENSP000002624194) via UniProtKB, MINT, STRING, and/or I2D (see all 600)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CEP70Q8NHQ12, 3, ENSP000002649824MINT-67988 I2D: score=4 STRING: ENSP00000264982
    KRT15P190122, 3, ENSP000002540434MINT-66716 I2D: score=4 STRING: ENSP00000254043
    SMAD3P840222, 3MINT-61723 I2D: score=2 
    TLN1Q9Y4902, 3MINT-7947479 I2D: score=1 
    CCDC85BQ158341, 2, 3, ENSP000003116954EBI-740244,EBI-739674 MINT-66064 I2D: score=4 STRING: ENSP00000311695
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043981histone H4-K5 acetylation IDA--
    GO:0043982histone H4-K8 acetylation IDA--
    GO:0043984histone H4-K16 acetylation IDA--

    KANSL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KANSL1 (KANL1)

    Search CenterWatch for drugs/clinical trials and news about KANSL1 / KANL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KANSL1 gene (3 alternative transcripts): 
    NM_001193465.1  NM_001193466.1  NM_015443.3  

    Unigene Cluster for KANSL1:

    KAT8 regulatory NSL complex subunit 1
    Hs.648744  [show with all ESTs]
    Unigene Representative Sequence: NM_001193466
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000572218(uc010wkb.2 uc010wkc.2) ENST00000574590(uc010dav.3)
    ENST00000576870 ENST00000575318 ENST00000572904(uc002ikd.3) ENST00000262419(uc002ikc.3)
    ENST00000574963 ENST00000573682 ENST00000576137 ENST00000573286 ENST00000572679
    ENST00000577114 ENST00000576248 ENST00000574655 ENST00000571698 ENST00000576739
    ENST00000432791 ENST00000393476

    miRNA
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    Additional mRNA sequence: 

    AB033093.1 AK291259.1 AK310569.1 AL117476.1 AL137317.1 BC035892.1 BC098376.1 BX538006.1 
    XR_159183.1 XR_159184.1 

    17 DOTS entries:

    DT.311087  DT.101975466  DT.100025111  DT.120895352  DT.120895591  DT.95272699  DT.40282897  DT.100742719 
    DT.92064598  DT.101955640  DT.100742722  DT.91904158  DT.95133422  DT.99958218  DT.100876496  DT.95272698 
    DT.97769370 

    24/196 AceView cDNA sequences (see all 196):

    AA363847 AA709349 AL118845 AL518347 F03848 BM312409 AW005191 BU542893 
    AA630638 AL042870 BU187705 Z36863 BE772350 BQ712537 Z39170 AI140989 
    BC035892 BQ053430 H88242 BF880731 BM545743 BQ651450 AA746494 BM915920 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for KANSL1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
    SP1:        -                                                     -     -     -           -                       -                                 
    SP2:                                                              -     -     -           -                       -                                 
    SP3:                                                                                      -     -     -           -                                 
    SP4:                                                                                                                                                
    SP5:                                                              -     -     -           -                       -                                 


    ECgene alternative splicing isoforms for KANSL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KANSL1 expression in normal human tissues (normalized intensities)      KANSL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCTGTCTT
    KANSL1 Expression
    About this image


    KANSL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   
     
     Thyroid (Endocrine System)    fully expand to see all 2 entries
             thyroid gland ; glandular cells   

    See KANSL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KANSL1

    SOURCE GeneReport for Unigene cluster: Hs.648744

    UniProtKB/Swiss-Prot: KANL1_HUMAN, Q7Z3B3
    Tissue specificity: Expressed in the brain

        SABiosciences Custom PCR Arrays for KANSL1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KANSL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KANSL1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kansl11 , 5 RIKEN cDNA 1700081L11 gene5
    KAT8 regulatory NSL complex subunit 11
    89.77(n)1
    90.93(a)1
      11 (67.79 cM)5
    767191  NM_001081045.11  NP_001074514.11 
     1043335015 
    chicken
    (Gallus gallus)
    Aves KANSL11 KAT8 regulatory NSL complex subunit 1 74.78(n)
    77.29(a)
      419961  XM_003642786.1  XP_003642834.1 
    lizard
    (Anolis carolinensis)
    Reptilia KANSL16
    --
    Uncharacterized protein
    72(a)
    33(a)
    1 ↔ 1
    possible ortholog
    6(67045952-67181879)
    GL343620.1(258025-290900)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.28482 Xenopus laevis transcribed sequence with weak similarity more 72.34(n)    BU908160.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5678841 MLL1/MLL complex subunit KIAA1267-like 55.21(n)
    50.1(a)
      567884  XM_691191.4  XP_696283.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta wah6
    waharan
    9(a)
    1 → many
    3R(11619498-11627647)


    ENSEMBL Gene Tree for KANSL1 (if available)
    TreeFam Gene Tree for KANSL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KANSL1 gene
    KANSL1L2  
    2 SIMAP similar genes for KANSL1 using alignment to 4 protein entries:     KANL1_HUMAN (see all proteins):
    KIAA1267    KANSL1L

    KANSL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KANSL1
    PGOHUM00000237097


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3960 SNPs in KANSL1 are shown (see all 3960)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0495154
    ----see VAR_0495152 K T mis40--------
    VAR_0495174
    ----see VAR_0495172 N D mis40--------
    rs25322341,2
    C,F,O,A,H--39934469(-) GGAAAT/CTCGCA 1 -- us2k1 tfbs318Minor allele frequency- C:0.12NA NS EA CSA 1892
    rs1899224341,2
    C--44106951(+) GAGCAA/GCTTAG 3 -- int10--------
    rs1862160181,2
    C--44109087(+) AAGTTC/GCTCTT 3 -- int10--------
    rs1458631941,2
    C,F--44109450(+) AACGGG/ATATCC 6 /T /I mis11Minor allele frequency- A:0.00NA 4552
    rs1468481671,2
    C,F--44109554(+) TGGGAG/ATATTC 6 /Y syn11Minor allele frequency- A:0.00NA 4382
    rs1901428671,2
    C--44109674(+) CACACA/CAAGGA 3 -- int10--------
    rs1175901471,2
    C--44109932(+) AGATTC/TGTGTA 3 -- int11Minor allele frequency- T:0.01EA 120
    rs1868189851,2
    C--44110565(+) TGCAAC/TAGAGC 3 -- int10--------

    HapMap Linkage Disequilibrium report for KANSL1 (44107282 - 44302740 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KANSL1: --

    Human Gene Mutation Database (HGMD): KANSL1

    Locus Specific Mutation Databases (LSDB): KANSL1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KANSL1
    DNA2.0 Custom Variant and Variant Library Synthesis for KANSL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612452    OMIM disorders: --

    4 diseases for KANSL1:    About MalaCards
    kansl1-related intellectual disability syndrome    17q21.31 microdeletion syndrome    parkinson's disease    schizophrenia


    KANSL1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for KANSL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KANSL1 gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with KANSL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. Subunit composition and substrate specificity of a MO F-containing histone acetyltransferase distinct from the male-specific lethal ( MSL) complex. (PubMed id 20018852)1, 2 Cai Y....Conaway R.C. (2010)
    3. Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. (PubMed id 16543150)1, 2 Mendjan S....Akhtar A. (2006)
    4. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. (PubMed id 16227571)1, 2 Smith E.R.... Lucchesi J.C. (2005)
    5. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. A genomic sequence analysis of the mouse and human microtubule- associated protein tau. (PubMed id 11641718)1, 2 Poorkaj P.... Schellenberg G.D. (2001)
    9. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 284058 HGNC: 24565 AceView: LOC284058 Ensembl:ENSG00000120071 euGenes: HUgn284058
    ECgene: KANSL1 H-InvDB: KANSL1

    (According to HUGE)
    About This Section
    HUGE: KIAA1267

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KANSL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KANSL1 gene:
    Search GeneIP for patents involving KANSL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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