Aliases for KANK2 Gene
External Ids for KANK2 Gene
Previous HGNC Symbols for KANK2 Gene
Previous GeneCards Identifiers for KANK2 Gene
GeneCards Summary for KANK2 Gene
UniProtKB/Swiss-Prot for KANK2 Gene
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).