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KAL1 Gene

protein-coding GIFtS: 59

GC0XM008456

Kallmann syndrome 1 sequence
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: KAL, ADMLX)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
ADMLX ^², ³, ⁵
HHA ^²
KAL ^², ³
KALIG-1 ^¹, ²
KALIG1 ^³
KMS ^², ⁵
OTTHUMP00000022873 ^²
anosmin-1 ^²

Descriptions
Adhesion molecule-like X-linked ^², ³
Kallmann syndrome 1 protein ^²
Kallmann syndrome 1 sequence ^²
Kallmann syndrome interval gene 1 ^²
Kallmann syndrome protein ^³
Kallmann syndrome-1 sequence (anosmin-1) ^²

External Ids
HGNC: 6211¹
Entrez Gene: 3730²
UniProtKB: P23352³
Ensembl: ENSG00000011201⁷

Search outside databases for aliases for KAL1 gene

Previous GC identifers: GC0XM007368 GC0XM007232 GC0XM007843 GC0XM007908 GC0XM008306

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for KAL1:

Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in

sequence to proteins known to function in neural cell adhesion and axonal migration. In addition,

this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by

RefSeq]

UniProtKB/Swiss-Prot: KALM_HUMAN, P23352

Function: May be an adhesion-like molecule with anti-protease activity

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.32 Ensembl cytogenetic band: Xp22.31 HGNC cytogenetic band: Xp22.32

KAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XM008456: (about GC identifiers)

Start:	8,456,915 bp from pter
End:	8,660,227 bp from pter
Size:	203,313 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000023.9 NT_011757.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: KALM_HUMAN, P23352 (See protein sequence)

Recommended Name: Anosmin-1 precursor

Size: 680 amino acids; 76112 Da

Subcellular location: Cell surface

PDB structures from and Proteopedia :

1ZLG (3D)

Post-translational modifications:

N-glycosylated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_000207.2

ENSEMBL proteins:

ENSP00000262648

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KAL1)
	Human Recombinant Proteins from Abnova (KAL1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005578	proteinaceous extracellular matrix	TAS	8832397
GO:0005615	extracellular space	TAS	8842728
GO:0009986	cell surface	IEA	--

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Antibodies for KAL1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for KAL1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (KAL1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (KAL1)
	Novus Biologicals Antibodies for KAL1

Assays for KAL1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P23352

ProtoNet protein and cluster: P23352

1 Blocks protein family: IPB008197 4-disulphide core signature

UniProtKB/Swiss-Prot: KALM_HUMAN, P23352

Similarity: Contains 4 fibronectin type-III domains

Similarity: Contains 1 WAP domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KAL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KAL1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000216

Applied Biosystems Silencer® siRNAs for KAL1

Sigma-Aldrich siRNA for KAL1

Sigma-Aldrich shRNA Panels and shRNA for KAL1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000216
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000216
untagged cDNA clone in CMV expression vector: NM_000216

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000216

UniProtKB/Swiss-Prot: KALM_HUMAN, P23352

Function: May be an adhesion-like molecule with anti-protease activity

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004867	serine-type endopeptidase inhibitor activity	IEA	--
GO:0005201	extracellular matrix structural constituent	TAS	8842728
GO:0005515	protein binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for KAL1

5/23 Interacting proteins for KAL1 (ENSP00000262648³) via UniProtKB, MINT, and/or STRING (see all 23 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LMLN	ENSP00000328829³	STRING (score=.961)
PROKR2	ENSP00000217270³	STRING (score=.946)
HPSE	ENSP00000308107³	STRING (score=.929)
PROK2	ENSP00000295619³	STRING (score=.902)
NELF	ENSP00000360530³	STRING (score=.889)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006935	chemotaxis	TAS	8842728
GO:0007155	cell adhesion	TAS	1913827 1922361
GO:0007411	axon guidance	TAS	1922361

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for KAL1
3 Novoseek chemical compound relationships for KAL1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
heparan sulfate	32.87	4	16677626 (2)
isoleucine	23.37	1	15765064 (1)
steroid	16.68	2	17603054 (1), 10396356 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KAL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (KAL1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000216

Sigma-Aldrich siRNA for KAL1

Sigma-Aldrich shRNA Panels and shRNA for KAL1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000216

REFSEQ mRNAs for KAL1 gene:

NM_000216.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000216

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000216
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000216
                                 untagged cDNA clone in CMV expression vector: NM_000216

Additional cDNA sequence:

BC137426.1 BC137427.1 M97252.1 S60085.1 S60088.1 X60299.1

4 DOTS entries:

DT.444478 DT.413647 DT.100747896 DT.91640146

24/73 AceView cDNA sequences (see all 73 ):

AU117607 AI703187 BQ029898 CB306497 N89949 AA419498 BM473419 CB321733

CD642906 AL044781 S60088 AL120218 AI659512 BQ181212 CA435944 AH003768

M97252 AL704788 BI755921 AU123877 BM802132 NM_000216 BM981870 S60085

highest scoring ESTs for KAL1:

M97252 AI582702 S60085 X60299 AA057103 AA635598 AA970936 AI186695 AI432167 AI470092

Unigene Cluster for KAL1:

Kallmann syndrome 1 sequence

Hs.521869 [show with all ESTs]

Unigene Representative Sequence: NM_000216

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000262648

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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KAL1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KAL1

¹ / ² / ³

3 probe-sets matching KAL1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33158_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M97252	1.00	1.00	1.00	1
205206_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000216	0.60	1.00	0.82	1
205206_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks KAL1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTAGAGTTTG

SOURCE GeneReport for Unigene cluster: Hs.521869
Expression variation in blood from EXPOLDB for KAL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KAL1 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KAL1¹	--	Kallmann syndrome 1 sequence	81.33(n) 83.89(a)	610921 XM_848502.1 XP_853595.1
chimpanzee (Pan troglodytes)	KAL1¹	--	Kallmann syndrome 1 sequence	99.35(n) 99.51(a)	465480 XM_520920.2 XP_520920.2
cow (Bos taurus)	KAL1¹	--	Kallmann syndrome 1 sequence	83.4(n) 92.19(a)	525898 XM_604257.3 XP_604257.3
chicken (Gallus gallus)	KAL1¹	--	Kallmann syndrome 1 sequence	74.01(n) 77.81(a)	396395 NM_205424.1 NP_990755.1
zebrafish (Danio rerio)	AF163310.1²	--	--	76.35(n)	30630 AF163310.1

About this table Species with no ortholog for KAL1

ENSEMBL Gene Tree for KAL1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/799 NCBI SNPs in KAL1 are shown (see all 799 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 200)

AB	SNP ID	Valid	Chr X pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
--	rs1852400^1,2	A,C,F,H,O	8459905(+)	`GCAACT/ACTCTA`	1	--	ut3¹		11	EU EA WA NA	766
	rs808127^1,2	A,C,F,H,O	8458979(-)	`GATAGC/TTTCTC`	1	--	ut3¹ trp³		16	NA EA EU WA	1332
--	rs1918153^1,2	A,C,F,H,O	8459573(+)	`GATAAC/ATTGCT`	1	--	ut3¹		7	NA EU EA WA	554
--	rs6530181^1,2	A,C,F,H	8459030(+)	`GAAGAT/CTGTTT`	1	--	ut3¹		4	EU EA WA	420
--	rs5978893^1,2	A,C,F,H	8458875(+)	`AGTTCG/ATGTAA`	1	--	ut3¹ ese³		7	EU EA WA NA	548
--	rs6530183^1,2	A,C,F,H	8459107(+)	`CCAGCC/TTGTGA`	1	--	ut3¹ ese³		7	EU EA WA NA	546
--	rs6640166^1,2	A,C,F,H	8457510(+)	`ACCCAC/TGGCAT`	1	--	ut3¹		4	EU EA WA	420
--	rs1918154^1,2	A,F,H,O	8459667(+)	`AGCTAC/TGAAAA`	1	--	ut3¹ ese³		4	EU EA WA	418
--	rs5934443^1,2	A,C,F,H	8458463(+)	`ATCACG/ATTTTT`	1	--	ut3¹		7	EU EA WA NA	552
--	rs6638834^1,2	A,C,F,H	8458794(+)	`CTATGT/CAGAGA`	1	--	ut3¹ ese³		8	EU EA WA	733

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HapMap Linkage Disequilibrium images for KAL1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 308700

UniProtKB/Swiss-Prot: KALM_HUMAN, P23352

Defects in KAL1 are the cause of Kallmann syndrome type 1 (KAL1) [MIM:308700]; also known

as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or

hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in

gonadotropin-releasing hormone and probably results from a failure of embryonic migration of

gonadotropin-releasing hormone-synthesizing neurons. In some patients other developmental

anomalies can be present, which include renal agenesis, cleft lip and/or palate, selective tooth

agenesis, and bimanual synkinesis. In some cases anosmia may be absent or inconspicuous

10/14 Novoseek disease relationships for KAL1 gene (see all 14 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
kallmann syndrome	98.84	57	11124862 (5), 10585565 (3), 10670750 (3), 11456260 (3) (see all 43)
hypogonadism	85.84	3	7677154 (1), 9719154 (1), 17223984 (1)
renal agenesis	74.31	8	17603054 (4), 10210557 (1), 10076881 (1), 15571757 (1)
klinefelters syndrome	69.77	1	16882753 (1)
single gene defects	67.50	1	18385259 (1)
aplasia	65.10	4	8504298 (1), 1518845 (1), 8460158 (1), 11456260 (1)
ichthyosis	56.18	1	17603054 (1)
addisons disease	50.99	2	10727999 (1), 10527669 (1)
hormone deficiency	42.75	1	15004876 (1)
hypoplasia	41.12	1	10670750 (1)

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Genatlas disease: KAL1

Kallmann syndrome 1,characterized by hypogonadotropic hypogonadism and anosmia,maybe associated

with renal agenesis of olfactory lobes and ataxia,synkinesia,nystagmus,visual

defects,clubfoot,cleft palate,including rare cases of sporadic isolated GNRH deficiency

GeneTests: KAL1

Kallmann Syndrome

Human Gene Mutation Database: KAL1
Genetic Association Database: KAL1
Human Genome Epidemiology Navigator: KAL1 (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/111 PubMed articles for KAL1 gene (see all 111 ):

Clinical assessment and mutation analysis of Kallmann syndrome 1 (KAL1) and fibroblast growth factor receptor 1 (FGFR1, or KAL2) in five families and 18 sporadic patients. (PubMed id 15001591)^{3, 4, 6} Sato N.... Ogata T. (2004)
The importance of autosomal genes in Kallmann syndrome: genotype- phenotype correlations and neuroendocrine characteristics. (PubMed id 11297579)^{1, 3, 4} Oliveira L.M.B.... Vallejo M. (2001)
Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism. (PubMed id 17223984)^{1, 3, 4} Versiani B.R.... de Castro M. (2007)
A recurrent missense mutation in the KAL gene in patients with X- linked Kallmann's syndrome. (PubMed id 9589672)^{1, 3, 4} Maya-Nunez G....Mendez J.P. (1998)
Heterogeneity in the mutations responsible for X chromosome-linked Kallmann syndrome. (PubMed id 8504298)^{1, 3, 4} Hardelin J.-P.... Petit C. (1993)
Kallmann syndrome: 14 novel mutations in KAL1 and FGFR1 (KAL2). (PubMed id 15605412)^{1, 3, 4} Albuisson J.... Dode C. (2005)
The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons. (PubMed id 15471890)^{1, 3, 4} Cariboni A.... Maggi R. (2004)
Initial characterization of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous system. (PubMed id 8832397)^{1, 3, 4} Soussi-Yanicostas N.... Petit C. (1996)
The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules. (PubMed id 1913827)^{1, 3, 4} Legouis R....Petit C. (1991)
Molecular modelling and experimental studies of mutation and cell-adhesion sites in the fibronectin type III and whey acidic protein domains of human anosmin-1. (PubMed id 11463336)^{1, 2, 3} Robertson A....Bouloux P.M. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 3730	HGNC: 6211	AceView: KAL1	Ensembl:ENSG00000011201	euGenes: HUgn3730
ECgene: KAL1	H-InvDB: KAL1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GeneReviews	http://www.genetests.org/query?gene=KAL1

Licensable Technologies for KAL1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for KAL1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KAL1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KAL1		Antibodies for KAL1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KAL1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (KAL1)
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	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for KAL1

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Antibodies for KAL1

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KAL1 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for KAL1

Summaries
for KAL1

Genomic Location
for KAL1

Proteins
for KAL1

Protein Domains/
Families
for KAL1

Gene Function
for KAL1

Pathways & Interactions
for KAL1

Drugs & Compounds
for KAL1

Transcripts
for KAL1

Expression
for KAL1

Orthologs
for KAL1

Paralogs
for KAL1

SNPs/Variants
for KAL1

Disorders & Mutations
for KAL1

Medical News
for KAL1

Publications
for KAL1

Search for KAL1

Genome Databases showing KAL1

Other Databases showing KAL1

Specialized Databases showing KAL1

Licensable Technologies
for KAL1

Services
for KAL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KAL1 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor KAL1

Summariesfor KAL1

Genomic Locationfor KAL1

Proteinsfor KAL1

Protein Domains/Familiesfor KAL1

Gene Functionfor KAL1

Pathways & Interactionsfor KAL1

Drugs & Compoundsfor KAL1

Transcriptsfor KAL1

Expression for KAL1

Orthologsfor KAL1

Paralogsfor KAL1

SNPs/Variantsfor KAL1

Disorders & Mutationsfor KAL1

Medical Newsfor KAL1

Publicationsfor KAL1

Search for KAL1

Genome Databases showing KAL1

Other Databases showing KAL1

Specialized Databases showing KAL1

Licensable Technologiesfor KAL1

Servicesfor KAL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KAL1

Summaries
for KAL1

Genomic Location
for KAL1

Proteins
for KAL1

Protein Domains/
Families
for KAL1

Gene Function
for KAL1

Pathways & Interactions
for KAL1

Drugs & Compounds
for KAL1

Transcripts
for KAL1

Expression
for KAL1

Orthologs
for KAL1

Paralogs
for KAL1

SNPs/Variants
for KAL1

Disorders & Mutations
for KAL1

Medical News
for KAL1

Publications
for KAL1

Licensable Technologies
for KAL1

Services
for KAL1