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CD82 Gene

protein-coding GIFtS: 59

GC11P044544

CD82 molecule
(Previous names: kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)), CD82 antigen )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: ST6, KAI1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
4F9 ^²
C33 ^²
GR15 ^²
IA4 ^¹, ², ³
KAI1 ^², ³, ⁵
R2 ^¹, ²
SAR2 ^², ³, ⁵
ST6 ^², ³, ⁵
TSPAN27 ^¹, ², ³
Tetraspanin-27 ^³
Tspan-27 ^³

Descriptions
C33 antigen ^², ³
CD82 antigen ^¹, ², ³
CD82 molecule ^²
Inducible membrane protein R2 ^², ³
Metastasis suppressor Kangai-1 ^³
R2 leukocyte antigen ^²
Suppressor of tumorigenicity protein 6 ^³
kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) ^¹, ²
suppression of tumorigenicity 6 ^²
suppressor of tumorigenicity 6 ^²

External Ids
HGNC: 6210¹
Entrez Gene: 3732²
UniProtKB: P27701³
Ensembl: ENSG00000085117⁷

Search outside databases for aliases for CD82 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CD82:

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the

transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor

progression of human cancers and can be activated by p53 through a consensus binding sequence in

the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression

of these two proteins is associated with poor survival for prostate cancer patients. Two

alternatively spliced transcript variants encoding distinct isoforms have been found for this

gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: CD82_HUMAN, P27701

Function: Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway

Gene Wiki entry for CD82

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CD82 gene

Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.2

CD82 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P044544: (about GC identifiers)

Start:	44,543,717 bp from pter
End:	44,597,915 bp from pter
Size:	54,199 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_009237.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CD82_HUMAN, P27701 (See protein sequence)

Recommended Name: CD82 antigen

Size: 267 amino acids; 29626 Da

Subunit: Interacts directly with IGSF8

Subcellular location: Membrane; Multi-pass membrane protein

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001020015.1 NP_002222.1

ENSEMBL proteins:

ENSP00000339686 ENSP00000227155

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD82)
	Human Recombinant Proteins from Abnova (CD82)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	7754374
GO:0005887	integral to plasma membrane	TAS	1842498

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Antibodies for CD82:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for CD82
	R&D Systems Antibodies for CD82 (CD82/Kai-1)
	Antibodies from Abcam (CD82), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CD82)
	Novus Biologicals Antibodies for CD82

Assays for CD82:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P27701

ProtoNet protein and cluster: P27701

1 Blocks protein family: IPB000301 Transmembrane four family signature

UniProtKB/Swiss-Prot: CD82_HUMAN, P27701

Similarity: Belongs to the tetraspanin (TM4SF) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD82)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CD82)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001024844

Applied Biosystems Silencer® siRNAs for CD82

Sigma-Aldrich siRNA and siRNA Panels for CD82

Sigma-Aldrich shRNA Panels and shRNA for CD82

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CD82
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001024844
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001024844
untagged cDNA clones in CMV expression vector (see all 3): NM_001024844

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002231

UniProtKB/Swiss-Prot: CD82_HUMAN, P27701

Function: Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15205336

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for CD82

5/40 Interacting proteins for CD82 (ENSP00000227155³ P27701¹) via UniProtKB, MINT, and/or STRING (see all 40 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
VANGL1	Q8TAA9¹	STRING (score=.783) EBI-682379, EBI-682393
EGFR	ENSP00000275493³	STRING (score=.971)
ITGB1	ENSP00000364094³	STRING (score=.968)
TP53	ENSP00000269305³	STRING (score=.965)
APBB1	ENSP00000299402³	STRING (score=.954)

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CD82
4 Novoseek chemical compound relationships for CD82 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
at-61	84.65	1	9041184 (1)
digitonin	30.79	1	12938224 (1)
tyrosine	14.88	6	17215249 (4), 18395972 (1), 15454569 (1)
cholesterol	0.00	4	12938224 (1), 15454569 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD82)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CD82)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001024844

Sigma-Aldrich siRNA and siRNA Panels for CD82

Sigma-Aldrich shRNA Panels and shRNA for CD82

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001024844 NM_002231

REFSEQ mRNAs for CD82 gene (2 alternative transcripts):

NM_001024844.1 NM_002231.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001024844 NM_002231

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001024844
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001024844
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001024844

Additional cDNA sequence:

AK225410.1 AK225708.1 AK312677.1 AY303776.1 BC000726.2 BC001821.2 BT019761.1 BT019762.1

CR407650.1 CR542255.1 CR593263.1 CR606617.1 CR609000.1 CR615871.1 S48196.1 U20770.1

19 DOTS entries:

DT.100793427 DT.313063 DT.97844941 DT.100793432 DT.120712758 DT.120712722 DT.92442010 DT.100793426

DT.120712724 DT.91742256 DT.100793430 DT.120712720 DT.120712748 DT.120712751 DT.40261002 DT.95076548

DT.95076555 DT.120753710 DT.95315953

24/268 AceView cDNA sequences (see all 268 ):

BP366951 AI354379 BG654786 BE349302 BM353004 BE871165 CR606617 BM914425

BG759651 AU119042 BI753805 CR609000 BU196310 CR615871 AW168332 BU785750

AU077255 BE205860 BU785446 CR593263 BU185132 BM473622 BE293674 BG420128

highest scoring ESTs for CD82:

AA047296 AA148488 AA285230 AA492158 AA640702 AA641265 AA861959 AI358229 AI365988 AI635272

Unigene Cluster for CD82:

CD82 molecule

Hs.527778 [show with all ESTs]

Unigene Representative Sequence: NM_002231

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CD82 (see all 7 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	·	4c	·	4d	^	5	^	6	^	7	^	8a	·	8b	^	9a	·	9b
SP1:							-		-						-
SP2:							-		-						-		-
SP3:									-						-
SP4:															-
SP5:

About this scheme

ECgene alternative splicing isoforms for CD82

2 Ensembl transcripts including schematic representations:

ENST00000342935 ENST00000227155

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CD82 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CD82

¹ / ² / ³

3 probe-sets matching CD82 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32247_at*²^{, 3}	U95-A	2	1.00	0.91	1.00	1.00	X53795	0.80	1.00	0.91	1
203904_x_at²^{, 3}	U133-A	30	1.00	0.91	--	--	NM_002231	0.60	1.00	0.82	1
203904_x_at²	U133Plus2	30	1.00	0.91	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GAGAAGGTGC

SOURCE GeneReport for Unigene cluster: Hs.527778
UniProtKB/Swiss-Prot: CD82_HUMAN, P27701
Tissue specificity: Lymphoid specific

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CD82 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CD82¹	--	CD82 molecule	86.69(n) 82.13(a)	611384 XM_849049.1 XP_854142.1
chimpanzee (Pan troglodytes)	CD82¹	--	CD82 molecule	99.5(n) 99.63(a)	741685 XM_001159516.1 XP_001159516.1
cow (Bos taurus)	CD82¹	--	CD82 molecule	84.77(n) 77.15(a)	506713 XM_583194.3 XP_583194.2
rat (Rattus norvegicus)	Cd82¹	--	Cd82 molecule	78.07(n) 76.32(a)	83628 NM_031797.1 NP_113985.1
mouse (Mus musculus)	Cd82^{1, 5}	2 (49.60 cM)⁵	CD82 antigen^{1, 5}	79.57(n)¹ 76.69(a)¹	12521¹ NM_007656.3¹ NP_031682.1¹ AA682076⁵ AK135381⁵ (see all 20)

About this table Species with no ortholog for CD82

ENSEMBL Gene Tree for CD82

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CD82 gene

CD63² TSPAN8² CD37²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/367 NCBI SNPs in CD82 are shown (see all 367 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 182)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs934178^1,2	A,C,F,H	44542509(-)	`GTACGA/GGTGGA`	2	--	ng5¹		8		EU EA WA NA	628
--	rs4755266^1,2	A,C,H	44597368(+)	`GCCCAC/TCCTGA`	2	--	ut3¹		3		EU EA	294
	rs1139971^1,2	C,F,H	44596844(+)	`CCATCA/GTCGAG`	2	I/V	mis¹		8		EU EA WA	818
	rs12224174^1,2	H	44541727(+)	`tctgcC/Tataca`	2	--	ng5¹		4		EU EA WA	418
--	rs6485552^1,2	C	44597688(+)	`tcgagA/Cccatc`	2	--	ut3¹ ese³		0	--	--	--	--
	rs12419539^1,2	C	44542252(+)	`GCTACC/TTAGGT`	2	--	ng5¹		0	--	--	--	--
--	rs1063031^1,2	F	44597601(+)	`GGGGAG/AGAGGG`	2	--	ut3¹ ese³ trp³		1		MN	184
	rs883752^1,2	A,C,F,H	44593415(+)	`ATGGGC/TGGCAT`	2	G/G	syn¹		11		EU WA EA NA	906
	rs7107335^1,2	A,C,F,H	44597216(+)	`CACGTC/GCATTC`	2	V/V	syn¹ ese³		13		EA NA EU WA	1056
	rs2303865^1,2	A,C,F,H	44593409(-)	`CCCATC/TTCCTG`	2	E/E	syn¹		2		WA NA	178

About this table

HapMap Linkage Disequilibrium images for CD82 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600623 disorders: 176807

10/43 Novoseek disease relationships for CD82 gene (see all 43 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
metastasis	75.05	285	18028322 (6), 12753720 (6), 8813131 (6), 17283532 (6) (see all 99)
prostate cancer	60.20	79	10440748 (7), 8813131 (5), 9254900 (5), 11572762 (4) (see all 35)
cancer	53.28	96	9671393 (4), 11331321 (3), 9699525 (3), 10440748 (2) (see all 50)
pancreatic cancer	49.74	33	15944768 (5), 18286698 (5), 8895737 (4), 9699525 (4) (see all 11)
allelic loss	49.51	12	8813131 (5), 11895916 (1), 9126478 (1), 9254900 (1) (see all 5)
tumors	47.51	154	12684410 (5), 10568187 (5), 9736732 (5), 10873402 (5) (see all 58)
primary tumor	44.55	19	11895916 (2), 10582691 (2), 17308076 (2), 15592684 (1) (see all 11)
bladder cancer	42.31	27	17982617 (4), 10767717 (3), 10840154 (3), 9815782 (3) (see all 8)
metastatic cancer	37.60	4	16271511 (1), 11715465 (1)
carcinoma	36.01	33	15259074 (6), 18575327 (3), 12747469 (2), 19024519 (2) (see all 15)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/215 PubMed articles for CD82 gene (see all 215 ):

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. (PubMed id 7754374)^{1, 3, 4} Dong J.T. and Barrett J.C. (1995)
Genomic organization of the human KAI1 metastasis-suppressor gene. (PubMed id 9126478)^{1, 3, 4} Dong J.T.... Isaacs J.T. (1997)
C33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53, and CD63. (PubMed id 1401919)^{1, 3, 4} Imai T.... Yoshie O. (1992)
EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells. (PubMed id 12750295)^{3, 4} Zhang X.A.... Liu L. (2003)
A new superfamily of lymphoid and melanoma cell proteins with extensive homology to Schistosoma mansoni antigen Sm23. (PubMed id 1842498)^{3, 4} Gaugitsch H.W.... Baumruker T. (1991)
High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis. (PubMed id 11895916)^{1, 3} Uzawa K....Tanzawa H. (2002)
Loss of KAI1 expression in the progression of colorectal cancer. (PubMed id 10582691)^{1, 3} Lombardi D.P....Barrett J.C. (1999)
CD82, and CD63 in thyroid cancer. (PubMed id 15375577)^{1, 3} Chen Z....Hoang-Vu C. (2004)
[Role of tumor metastasis suppressor gene KAI1 in development of colorectal cancer] (PubMed id 12753720)^{1, 3} Yang J....Liu L.M. (2003)
KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer. (PubMed id 18712725)^{1, 3} Christgen M....Lehmann U. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3732	HGNC: 6210	AceView: KAI1	Ensembl:ENSG00000085117	euGenes: HUgn3732
ECgene: CD82	H-InvDB: CD82

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CD82	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for CD82
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CD82:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CD82-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CD82		Antibodies for CD82
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CD82		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CD82)
	Antibodies (CD82)
	Chimera RNAi (CD82)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (CD82)

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Search Tocris compounds for CD82

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Antibodies for CD82

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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CD82 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for CD82

Summaries
for CD82

Genomic Location
for CD82

Proteins
for CD82

Protein Domains/
Families
for CD82

Gene Function
for CD82

Pathways & Interactions
for CD82

Drugs & Compounds
for CD82

Transcripts
for CD82

Expression
for CD82

Orthologs
for CD82

Paralogs
for CD82

SNPs/Variants
for CD82

Disorders & Mutations
for CD82

Medical News
for CD82

Publications
for CD82

Search for CD82

Genome Databases showing CD82

Other Databases showing CD82

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Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CD82 (Gene Symbol)
4F9
C33
GR15
IA4
KAI1
R2
SAR2
ST6
TSPAN27
Tetraspanin-27
Tspan-27
C33 antigen
CD82 antigen
CD82 molecule
Inducible membrane protein R2
Metastasis suppressor Kangai-1
R2 leukocyte antigen
Suppressor of tumorigenicity protein 6
kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
suppression of tumorigenicity 6
suppressor of tumorigenicity 6

CD82 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor CD82

Summariesfor CD82

Genomic Locationfor CD82

Proteinsfor CD82

Protein Domains/Familiesfor CD82

Gene Functionfor CD82

Pathways & Interactionsfor CD82

Drugs & Compoundsfor CD82

Transcriptsfor CD82

Expression for CD82

Orthologsfor CD82

Paralogsfor CD82

SNPs/Variantsfor CD82

Disorders & Mutationsfor CD82

Medical Newsfor CD82

Publicationsfor CD82

Search for CD82

Genome Databases showing CD82

Other Databases showing CD82

Specialized Databases showing CD82

Licensable Technologiesfor CD82

Servicesfor CD82

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CD82

Summaries
for CD82

Genomic Location
for CD82

Proteins
for CD82

Protein Domains/
Families
for CD82

Gene Function
for CD82

Pathways & Interactions
for CD82

Drugs & Compounds
for CD82

Transcripts
for CD82

Expression
for CD82

Orthologs
for CD82

Paralogs
for CD82

SNPs/Variants
for CD82

Disorders & Mutations
for CD82

Medical News
for CD82

Publications
for CD82

Licensable Technologies
for CD82

Services
for CD82