KAAG1 Gene
protein-coding GIFtS: 38
GCID: GC06P024306
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kidney associated antigen 1
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Aliases
for KAAG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kidney Associated Antigen 11 2 | | RU2AS1 2 3 5 | | RU2 Antisense Gene Protein2 3 | | RU21 | | Kidney-Associated Antigen 12 |
Export aliases for KAAG1 gene to outside databasesPrevious GC identifers: GC06P024419 GC06P024465 GC06P024357 |
Summaries
for KAAG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KAAG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KAAG1 gene promoter:
HFH-3 E2F-4 E2F-3a E2F-5 E2F-2 E4BP4 GATA-1 FOXI1 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KAAG1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KAAG1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.3 HGNC cytogenetic band: 6p22.1KAAG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P024306: view genomic region
(about GC identifiers)
Start:
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24,357,131 bp from pter |
End:
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24,358,512 bp from pter |
Size:
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1,382 bases |
Orientation:
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plus strand |
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Proteins
for KAAG1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KAAG1_HUMAN, Q9UBP8 (See
protein sequence)Recommended Name: Kidney-associated antigen 1 Size: 84 amino acids; 8969 DaExplore the universe of human proteins at neXtProt for KAAG1: NX_Q9UBP8
KAAG1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_851854.1
ENSEMBL proteins: ENSP00000274766
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
KAAG1 for ontologies About GeneDecksing
KAAG1 Antibody Products:
Assay Products for KAAG1: |
Protein
Domains /
Families
for KAAG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9UBP8 |
Function
for KAAG1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KAAG1 (NM_181337) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KAAG1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAAG1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAAG1 |
|
Pathways & Interactions
for KAAG1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KAAG1
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
KAAG1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KAAG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KAAG1
Search CenterWatch for drugs/clinical trials and news about KAAG1
|
Transcripts
for KAAG1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KAAG1 gene: NM_181337.3 Unigene Cluster for KAAG1: Kidney associated antigen 1 Hs.697888 [show with all ESTs]Unigene Representative Sequence: NM_1813371 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000274766(uc003ndz.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KAAG1 (NM_181337) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KAAG1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAAG1 |
Additional cDNA sequence: AF181722.1 BC119739.1 BC119740.1 3 DOTS entries: DT.40127026 DT.97780424 DT.92013933 6 AceView cDNA sequences: AF181722 NM_181337 BC069035 BQ953400 BG749180 BF364659
GeneLoc Exon Structure
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Expression
for KAAG1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KAAG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGGGGTGG
About this image
See KAAG1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KAAG1
SOURCE GeneReport for Unigene cluster: Hs.697888
UniProtKB/Swiss-Prot: KAAG1_HUMAN, Q9UBP8Tissue specificity: Expressed in testis and kidney, and, at lower levels, in urinary bladder and liver. Expressed by ahigh proportion of tumors of various histologic origin, including melanomas, sarcomas and colorectal carcinomas
SABiosciences Custom PCR Arrays for KAAG1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KAAG1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat KAAG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KAAG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KAAG1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAAG1 |
Orthologs
for KAAG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for KAAG1 (if available)
TreeFam Gene Tree for KAAG1 (if available) |
Paralogs
for KAAG1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KAAG1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KAAG1 |
|
Disorders
/ Diseases
for KAAG1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KAAG1 for disorders About GeneDecksing
OMIM gene information: 608211
OMIM disorders: --
4  diseases for KAAG1: About MalaCardsdyslexia sarcoma melanoma carcinoma
1 disease from the University of Copenhagen DISEASES database for KAAG1:Dyslexia Export disorders for KAAG1 gene to outside databases
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Publications
for KAAG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KAAG1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KAAG1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription. (PubMed id 10601354)1, 2, 3 Van den Eynde B.J.... Boon T. (1999)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KAAG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KAAG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KAAG1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KAAG1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KAAG1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KAAG1 gene:
Search GeneIP for patents involving KAAG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KAAG1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KAAG1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KAAG1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KAAG1 | | | OriGene Protein Over-expression Lysate for KAAG1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KAAG1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KAAG1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KAAG1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  |  |  |  | | | | | | Recombinant Protein for KAAG1 |
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 | | | KAAG1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KAAG1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KAAG1 |
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