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Aliases for KAAG1 Gene

Aliases for KAAG1 Gene

  • Kidney Associated Antigen 1 2 3 5
  • RU2 Antisense Gene Protein 3 4
  • RU2AS 3 4
  • Kidney-Associated Antigen 1 3

External Ids for KAAG1 Gene

Previous GeneCards Identifiers for KAAG1 Gene

  • GC06P024419
  • GC06P024465
  • GC06P024357

Summaries for KAAG1 Gene

GeneCards Summary for KAAG1 Gene

KAAG1 (Kidney Associated Antigen 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KAAG1 Gene

Genomics for KAAG1 Gene

Regulatory Elements for KAAG1 Gene

Enhancers for KAAG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around KAAG1 on UCSC Golden Path with GeneCards custom track

Promoters for KAAG1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for KAAG1 Gene

24,356,903 bp from pter
24,358,284 bp from pter
1,382 bases
Plus strand

Genomic View for KAAG1 Gene

Genes around KAAG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KAAG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KAAG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KAAG1 Gene

Proteins for KAAG1 Gene

  • Protein details for KAAG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Kidney-associated antigen 1
    Protein Accession:

    Protein attributes for KAAG1 Gene

    84 amino acids
    Molecular mass:
    8969 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KAAG1 Gene

Post-translational modifications for KAAG1 Gene

No Post-translational modifications

Other Protein References for KAAG1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KAAG1 Gene

Domains & Families for KAAG1 Gene

Protein Domains for KAAG1 Gene


Suggested Antigen Peptide Sequences for KAAG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KAAG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KAAG1 Gene

Function for KAAG1 Gene

Phenotypes for KAAG1 Gene

GenomeRNAi human phenotypes for KAAG1:
genes like me logo Genes that share phenotypes with KAAG1: view

Animal Model Products

CRISPR Products

miRNA for KAAG1 Gene

miRTarBase miRNAs that target KAAG1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KAAG1 Gene

Localization for KAAG1 Gene

Subcellular locations from

Jensen Localization Image for KAAG1 Gene COMPARTMENTS Subcellular localization image for KAAG1 gene
Compartment Confidence
cytosol 2
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for KAAG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with KAAG1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KAAG1 Gene

Pathways & Interactions for KAAG1 Gene

SuperPathways for KAAG1 Gene

No Data Available

Interacting Proteins for KAAG1 Gene

Gene Ontology (GO) - Biological Process for KAAG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 10601354
genes like me logo Genes that share ontologies with KAAG1: view

No data available for Pathways by source and SIGNOR curated interactions for KAAG1 Gene

Drugs & Compounds for KAAG1 Gene

No Compound Related Data Available

Transcripts for KAAG1 Gene

mRNA/cDNA for KAAG1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KAAG1 Gene

Kidney associated antigen 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KAAG1 Gene

No ASD Table

Relevant External Links for KAAG1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KAAG1 Gene

mRNA expression in normal human tissues for KAAG1 Gene

NURSA nuclear receptor signaling pathways regulating expression of KAAG1 Gene:


SOURCE GeneReport for Unigene cluster for KAAG1 Gene:


mRNA Expression by UniProt/SwissProt for KAAG1 Gene:

Tissue specificity: Expressed in testis and kidney, and, at lower levels, in urinary bladder and liver. Expressed by a high proportion of tumors of various histologic origin, including melanomas, sarcomas and colorectal carcinomas.
genes like me logo Genes that share expression patterns with KAAG1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for KAAG1 Gene

Orthologs for KAAG1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for KAAG1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KAAG1 34
  • 100 (n)
  • 100 (a)
KAAG1 35
  • 100 (a)
Species where no ortholog for KAAG1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KAAG1 Gene

Gene Tree for KAAG1 (if available)
Gene Tree for KAAG1 (if available)

Paralogs for KAAG1 Gene

No data available for Paralogs for KAAG1 Gene

Variants for KAAG1 Gene

Structural Variations from Database of Genomic Variants (DGV) for KAAG1 Gene

Variant ID Type Subtype PubMed ID
nsv1026638 CNV gain 25217958

Variation tolerance for KAAG1 Gene

Residual Variation Intolerance Score: 67.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.22; 4.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KAAG1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for KAAG1 Gene

Disorders for KAAG1 Gene

Relevant External Links for KAAG1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for KAAG1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KAAG1 Gene

Publications for KAAG1 Gene

  1. A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription. (PMID: 10601354) Van den Eynde B.J. … Boon T. (J. Exp. Med. 1999) 2 3 4 65
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 65
  3. PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. (PMID: 26598620) Dart A.E. … Wells C.M. (J. Cell Biol. 2015) 3 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for KAAG1 Gene

Sources for KAAG1 Gene

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