Aliases for JRK Gene
External Ids for JRK Gene
Previous GeneCards Identifiers for JRK Gene
This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for JRK Gene
JRK (Jrk Helix-Turn-Helix Protein) is a Protein Coding gene. Diseases associated with JRK include Childhood Absence Epilepsy and Epilepsy, Generalized, With Febrile Seizures Plus, Type 5. GO annotations related to this gene include nucleic acid binding and mRNA binding. An important paralog of this gene is JRKL.
UniProtKB/Swiss-Prot for JRK Gene
May bind DNA.