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Aliases for JPX Gene

Subcategory (RNA class) for JPX Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for JPX Gene

  • JPX Transcript, XIST Activator (Non-Protein Coding) 2 3 5
  • Expressed Neighbor Of XIST 2 3
  • Just Proximal To XIST 2 3
  • Non-Protein Coding RNA 183 2
  • NCRNA00183 3
  • LINC00183 3
  • DCBALD06 3
  • ENOX 3

External Ids for JPX Gene

Previous HGNC Symbols for JPX Gene

  • NCRNA00183

Previous GeneCards Identifiers for JPX Gene

  • GC0XP073166
  • GC0XP073946
  • GC0XP073950
  • GC0XP073952
  • GC0XP073953

Summaries for JPX Gene

Entrez Gene Summary for JPX Gene

  • JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]

GeneCards Summary for JPX Gene

JPX (JPX Transcript, XIST Activator (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for JPX Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JPX Gene

Genomics for JPX Gene

Regulatory Elements for JPX Gene

Enhancers for JPX Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF073943 1.2 ENCODE 72.2 +0.2 216 2.2 MLX YBX1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 RAB11FIP1P1 ENSG00000271430 JPX FTX DDX3P1 ENSG00000271199 RN7SL648P TOMM20P4 ENSG00000228906 ENSG00000271533
GH0XF073850 1.1 ENCODE 42.5 -92.7 -92650 2.3 PKNOX1 CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF302 ZNF548 FOS ZNF263 RAB11FIP1P1 JPX ENSG00000271430 RN7SL648P TOMM20P4 FTX ZCCHC13 ENSG00000271533 ENSG00000234969 ENSG00000271199
GH0XF073915 1 Ensembl ENCODE 35 -26.6 -26619 4.0 TBP JUN FEZF1 RAD21 HIC1 ZNF324 FOS KLF8 ZNF362 CEBPB JPX ENSG00000228906 PIR36096
GH0XF073977 1 Ensembl ENCODE 35 +33.4 33359 1.2 KLF1 TBL1XR1 BMI1 EBF1 ZIC2 CREM SRF RFX1 MTA2 CBFB JPX ENSG00000228906 ENSG00000271199 ENSG00000270223
GH0XF074062 0.6 ENCODE 35.1 +119.3 119343 1.4 ZNF217 GATA3 PKNOX1 CTBP1 DPF2 ATF2 JPX GC0XP074066 LOC101928425
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around JPX on UCSC Golden Path with GeneCards custom track

Promoters for JPX Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000479675 477 2800 MLX YBX1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3

Genomic Location for JPX Gene

Chromosome:
X
Start:
73,944,324 bp from pter
End:
74,070,408 bp from pter
Size:
126,085 bases
Orientation:
Plus strand

Genomic View for JPX Gene

Genes around JPX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
JPX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for JPX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JPX Gene

Proteins for JPX Gene

Post-translational modifications for JPX Gene

No Post-translational modifications

No data available for DME Specific Peptides for JPX Gene

Domains & Families for JPX Gene

Gene Families for JPX Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with JPX: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for JPX Gene

Function for JPX Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for JPX Gene

Localization for JPX Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for JPX gene
Compartment Confidence
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for JPX Gene

Pathways & Interactions for JPX Gene

No Data Available

Interacting Proteins for JPX Gene

Gene Ontology (GO) - Biological Process for JPX Gene

None

No data available for Pathways by source and SIGNOR curated interactions for JPX Gene

Transcripts for JPX Gene

mRNA/cDNA for JPX Gene

(4) Additional mRNA sequences :
(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for JPX Gene

JPX transcript, XIST activator (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for JPX Gene

No ASD Table

Relevant External Links for JPX Gene

GeneLoc Exon Structure for
JPX
ECgene alternative splicing isoforms for
JPX

Expression for JPX Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for JPX Gene

NURSA nuclear receptor signaling pathways regulating expression of JPX Gene:

JPX

SOURCE GeneReport for Unigene cluster for JPX Gene:

Hs.648316
genes like me logo Genes that share expression patterns with JPX: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for JPX Gene

Orthologs for JPX Gene

Evolution for JPX Gene

ENSEMBL:
Gene Tree for JPX (if available)
TreeFam:
Gene Tree for JPX (if available)

No data available for Orthologs for JPX Gene

Paralogs for JPX Gene

No data available for Paralogs for JPX Gene

Variants for JPX Gene

Sequence variations from dbSNP and Humsavar for JPX Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs11093442 -- 73,944,198(+) GGCTG(C/G)GGCAC upstream-variant-2KB
rs11093445 -- 74,052,834(+) ggacc(A/C)agcta intron-variant
rs111339997 -- 74,069,287(+) TGTGA(C/T)CCCAC intron-variant, nc-transcript-variant
rs111393569 -- 73,948,459(+) GGGAA(C/G)CATGT intron-variant
rs111408846 -- 74,051,652(+) GCACT(C/T)CAGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for JPX Gene

Variant ID Type Subtype PubMed ID
dgv223n73 CNV deletion 24416366
esv1005511 CNV insertion 20482838
esv2067362 CNV deletion 18987734
esv2656629 CNV deletion 23128226
esv2656958 CNV deletion 23128226
esv2673779 CNV deletion 23128226
esv29793 CNV loss 19812545
esv3558978 CNV deletion 23714750
nsv6960 CNV insertion 18451855

Relevant External Links for JPX Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
JPX

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for JPX Gene

Disorders for JPX Gene

Relevant External Links for JPX

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
JPX

No disorders were found for JPX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for JPX Gene

Publications for JPX Gene

  1. The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. (PMID: 21029862) Tian D. … Lee J.T. (Cell 2010) 2 3 64
  2. [Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]. (PMID: 21254562) Kolesnikov N.N. … Elisafenko E.A. (Genetika 2010) 2 3 64
  3. Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes. (PMID: 17567985) Tsuritani K. … Suzuki Y. (Genome Res. 2007) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for JPX Gene

Sources for JPX Gene

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