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Aliases for JPX Gene

Subcategory (RNA class) for JPX Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for JPX Gene

  • JPX Transcript, XIST Activator (Non-Protein Coding) 2 3 5
  • Expressed Neighbor Of XIST 2 3
  • Just Proximal To XIST 2 3
  • Non-Protein Coding RNA 183 2
  • NCRNA00183 3
  • LINC00183 3
  • DCBALD06 3
  • ENOX 3

External Ids for JPX Gene

Previous HGNC Symbols for JPX Gene

  • NCRNA00183

Previous GeneCards Identifiers for JPX Gene

  • GC0XP073166
  • GC0XP073946
  • GC0XP073950
  • GC0XP073952
  • GC0XP073953
  • GC0XP073954
  • GC0XP073955

Summaries for JPX Gene

Entrez Gene Summary for JPX Gene

  • JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]

GeneCards Summary for JPX Gene

JPX (JPX Transcript, XIST Activator (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for JPX Gene

Additional gene information for JPX Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JPX Gene

Genomics for JPX Gene

Regulatory Elements for JPX Gene

Enhancers for JPX Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH073943 1.2 ENCODE 72.1 +0.4 356 2 MLX FEZF1 DMAP1 YBX1 YY1 ZNF416 ZNF143 ZNF548 SP3 ZC3H11A FTX ENSG00000271199 RAB11FIP1P1 JPX DDX3P1 RN7SL648P CHIC1 ENSG00000228906 TOMM20P4 ENSG00000271533
GH0XH073850 1.1 ENCODE 51.3 -92.5 -92510 2 PKNOX1 ARNT SIN3A FEZF1 ZNF2 YY1 ZNF766 ZNF302 ZNF143 ZNF548 RAB11FIP1P1 JPX ENSG00000271199 RN7SL648P FTX DDX3P1 ENSG00000234969 ENSG00000271533 MKRN5P TOMM20P4
GH0XH073915 1 Ensembl ENCODE 35 -26.5 -26479 4 TBP JUN FEZF1 RAD21 ZNF324 HIC1 POLR2A KLF8 ZNF362 CEBPB JPX ENSG00000228906 PIR36096
GH0XH073977 1 ENCODE dbSUPER 35 +33.5 33499 1 KLF1 TBL1XR1 EBF1 BMI1 ZIC2 ZSCAN5C RUNX3 IKZF2 CREM MAZ JPX ENSG00000228906 ENSG00000271199 GC0XP074017
GH0XH073965 0.8 ENCODE dbSUPER 35.1 +22.1 22056 1 ZNF362 ZFP3 PRDM10 PRDM1 JPX ENSG00000271533 ENSG00000271199 ENSG00000228906
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around JPX on UCSC Golden Path with GeneCards custom track

Promoters for JPX Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000247247 516 2201 MLX FEZF1 DMAP1 YBX1 YY1 ZNF416 ZNF143 ZNF548 SP3 ZC3H11A

Genomic Location for JPX Gene

Chromosome:
X
Start:
73,944,184 bp from pter
End:
74,070,408 bp from pter
Size:
126,225 bases
Orientation:
Plus strand

Genomic View for JPX Gene

Genes around JPX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
JPX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for JPX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JPX Gene

Proteins for JPX Gene

Post-translational modifications for JPX Gene

No Post-translational modifications

No data available for DME Specific Peptides for JPX Gene

Domains & Families for JPX Gene

Gene Families for JPX Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with JPX: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for JPX Gene

Function for JPX Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for JPX
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for JPX Gene

Localization for JPX Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for JPX gene
Compartment Confidence
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for JPX Gene

Pathways & Interactions for JPX Gene

No Data Available

Interacting Proteins for JPX Gene

Gene Ontology (GO) - Biological Process for JPX Gene

None

No data available for Pathways by source and SIGNOR curated interactions for JPX Gene

Drugs & Compounds for JPX Gene

No Compound Related Data Available

Transcripts for JPX Gene

mRNA/cDNA for JPX Gene

(4) Additional mRNA sequences :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for JPX Gene

JPX transcript, XIST activator (non-protein coding):
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for JPX
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for JPX Gene

No ASD Table

Relevant External Links for JPX Gene

GeneLoc Exon Structure for
JPX
ECgene alternative splicing isoforms for
JPX

Expression for JPX Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for JPX Gene

NURSA nuclear receptor signaling pathways regulating expression of JPX Gene:

JPX

SOURCE GeneReport for Unigene cluster for JPX Gene:

Hs.648316
genes like me logo Genes that share expression patterns with JPX: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for JPX Gene

Orthologs for JPX Gene

Evolution for JPX Gene

ENSEMBL:
Gene Tree for JPX (if available)
TreeFam:
Gene Tree for JPX (if available)

No data available for Orthologs for JPX Gene

Paralogs for JPX Gene

No data available for Paralogs for JPX Gene

Variants for JPX Gene

Sequence variations from dbSNP and Humsavar for JPX Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000069943 -- 73,975,120(+) CTTTC(A/G)TCTAT intron-variant
rs1000093565 -- 74,018,003(+) ATATA(A/G)GAAGA intron-variant
rs1000119576 -- 73,952,712(+) AGTTG(A/G)AGAGT intron-variant
rs1000157822 -- 73,960,838(+) TTGTT(A/C)GTTGT intron-variant
rs1000171241 -- 74,009,192(+) CAGAA(A/G)TCTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for JPX Gene

Variant ID Type Subtype PubMed ID
dgv223n73 CNV deletion 24416366
esv1005511 CNV insertion 20482838
esv2067362 CNV deletion 18987734
esv2656629 CNV deletion 23128226
esv2656958 CNV deletion 23128226
esv2673779 CNV deletion 23128226
esv29793 CNV loss 19812545
esv3558978 CNV deletion 23714750
nsv6960 CNV insertion 18451855

Relevant External Links for JPX Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
JPX

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for JPX Gene

Disorders for JPX Gene

Relevant External Links for JPX

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
JPX

No disorders were found for JPX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for JPX Gene

Publications for JPX Gene

  1. [Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]. (PMID: 21254562) Kolesnikov NN … Elisafenko EA (Genetika 2010) 2 3 60
  2. The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. (PMID: 21029862) Tian D … Lee JT (Cell 2010) 2 3 60
  3. A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes. (PMID: 28854954) Hezroni H … Ulitsky I (Genome biology 2017) 3 60
  4. Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes. (PMID: 17567985) Tsuritani K … Suzuki Y (Genome research 2007) 3 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60

Products for JPX Gene

Sources for JPX Gene

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