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JOSD1 Gene

protein-coding   GIFtS: 51
GCID: GC22M039081

Josephin Domain Containing 1

  Search for JOSD1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Josephin Domain Containing 11 2     dJ508I15.22
Josephin Domain-Containing Protein 12 3     Josephin Domain-Containing 12
KIAA00633 5     EC 3.4.19.123
Josephin-12     JSPH13

External Ids:    HGNC: 289531   Entrez Gene: 99292   Ensembl: ENSG000001002217   OMIM: 6153235   UniProtKB: Q150403   

Export aliases for JOSD1 gene to outside databases

Previous GC identifers: GC22M037407 GC22M022047


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for JOSD1 Gene:
JOSD1 (Josephin domain containing 1) is a protein-coding gene. GO annotations related to this gene include omega peptidase activity. An important paralog of this gene is JOSD2.

UniProtKB/Swiss-Prot: JOS1_HUMAN, Q15040
Function: Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and
'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase
macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell
motility independently of its catalytic activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the JOSD1 gene promoter:
         STAT1   STAT1beta   LCR-F1   Evi-1   STAT1alpha   N-Myc   POU2F1   CP2   POU2F1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidJOSD1 promoter sequence
   Search Chromatin IP Primers for JOSD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat JOSD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

JOSD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
JOSD1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M039081:  view genomic region     (about GC identifiers)

Start:
39,081,548 bp from pter      End:
39,097,561 bp from pter
Size:
16,014 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: JOS1_HUMAN, Q15040 (See protein sequence)
Recommended Name: Josephin-1  
Size: 202 amino acids; 23198 Da
Subunit: Interacts with beta-actin/ACTB
Sequence caution: Sequence=BAA06682.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K712

Explore the universe of human proteins at neXtProt for JOSD1: NX_Q15040

Explore proteomics data for JOSD1 at MOPED

Post-translational modifications: 

  • Monoubiquitinated (By similarity). Ubiquitination activates deubiquitination activity in vitro1
  • Ubiquitination2 at Lys74, Lys180
  • Modification sites at PhosphoSitePlus

  • See JOSD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055691.1  
    ENSEMBL proteins: 
     ENSP00000216039   ENSP00000444798   ENSP00000410010   ENSP00000415189   ENSP00000393131  
     ENSP00000405182  

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    Cloud-Clone Corp. CLIAs for JOSD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006155 Josephin

    Graphical View of Domain Structure for InterPro Entry Q15040

    ProtoNet protein and cluster: Q15040

    UniProtKB/Swiss-Prot: JOS1_HUMAN, Q15040
    Similarity: Contains 1 Josephin domain


    JOSD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: JOS1_HUMAN, Q15040
    Function: Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and
    'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase
    macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell
    motility independently of its catalytic activity
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Number (IUBMB): EC 3.4.19.121

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008242omega peptidase activity IEA--
         
    JOSD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for JOSD1:
     Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for JOSD1
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    miRNA
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    miRTarBase miRNAs that target JOSD1:
    hsa-mir-186-5p (MIRT045025), hsa-mir-26b-5p (MIRT029639)

    Block miRNA regulation of human, mouse, rat JOSD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate JOSD1 (see all 96):
    hsa-miR-520e hsa-miR-106a hsa-miR-938 hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-298 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidJOSD1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for JOSD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    JOS1_HUMAN, Q15040: Cell membrane. Cytoplasm. Note=Ubiquitination increases localization the plasma membrane. In
    the cytosol, the unubiquinated form may be associated with the cytoskeleton via ACTB-binding
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--

    JOSD1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for JOSD1
    Interactions:

        Search GeneGlobe Interaction Network for JOSD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for JOSD1 (Q150403 ENSP000002160394) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000215641P143733I2D: score=1 
    ENSG00000229006P143733I2D: score=1 
    ENSG00000234495P143733I2D: score=1 
    ENSG00000237071P143733I2D: score=1 
    TRIM27P143733I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----

    JOSD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for JOSD1 (JOS1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for JOSD1 gene: 
    NM_014876.5  

    Unigene Cluster for JOSD1:

    Josephin domain containing 1
    Hs.3094  [show with all ESTs]
    Unigene Representative Sequence: NM_014876
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216039(uc003awf.3) ENST00000545590 ENST00000482442 ENST00000427389
    ENST00000412832 ENST00000417712 ENST00000456626 ENST00000462610 ENST00000490169
    ENST00000493939
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate JOSD1 (see all 96):
    hsa-miR-520e hsa-miR-106a hsa-miR-938 hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-298 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidJOSD1 3' UTR sequence
    Inhib. RNA
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    OriGene qPCR primer pairs and template standards for JOSD1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat JOSD1
      QuantiTect SYBR Green Assays in human, mouse, rat JOSD1
      QuantiFast Probe-based Assays in human, mouse, rat JOSD1

    Additional mRNA sequence: 

    AK291827.1 BC015026.2 BX538323.1 CR456473.1 CR456923.1 D31884.1 

    11 DOTS entries:

    DT.454568  DT.100645098  DT.95171932  DT.95178630  DT.100893826  DT.120671404  DT.120671397  DT.91765621 
    DT.100893829  DT.65286679  DT.95171929 

    Selected AceView cDNA sequences (see all 308):

    AI521636 AI867758 AA347008 BU542301 AW168411 AW630650 BQ775648 AI783803 
    BU625613 CR596979 BQ880930 AI200974 CA444340 AV708886 BQ929893 BG231784 
    BQ024917 AI471247 BE044627 AW613896 AA378680 BM785447 AW139327 BQ638591 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for JOSD1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b
    SP1:        -     -                                             
    SP2:                                                            
    SP3:              -                                             
    SP4:                                -                           


    ECgene alternative splicing isoforms for JOSD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    JOSD1 expression in normal human tissues (normalized intensities)      JOSD1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGATGCCCA
    JOSD1 Expression
    About this image


    JOSD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)
             Bone Marrow
    JOSD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    JOSD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.3094
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for JOSD1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Josd15 Josephin domain containing 1   --   15 (37.85 cM) 79674250 
    chicken
    (Gallus gallus)
    Aves JOSD11 Josephin domain containing 1 84.98(n)
    94.55(a)
      418023  XM_416259.4  XP_416259.1 
    lizard
    (Anolis carolinensis)
    Reptilia JOSD16
    Josephin domain containing 1
    91(a)
    1 ↔ 1
    5(24158080-24166393)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BG511968.12   -- 81.43(n)    BG511968.1 
    zebrafish
    (Danio rerio)
    Actinopterygii josd11 Josephin domain containing 1 71.31(n)
    75.12(a)
      767655  NM_001076595.2  NP_001070063.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG37816
    --
    37(a)
    1 → many
    X(6155202-6156152)
    worm
    (Caenorhabditis elegans)
    Secernentea josd-16
    Protein JOSD-1 (josd-1) mRNA, complete cds
    38(a)
    1 → many
    III(2836639-2838457) WBGene00022190
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons JOSL1 JOSL 53.51(n)
    44.22(a)
      817514  NM_128518.1  NP_180525.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02652001 Os03g0265200 50.42(n)
    35(a)
      4332346  NM_001056181.1  NP_001049646.1 


    ENSEMBL Gene Tree for JOSD1 (if available)
    TreeFam Gene Tree for JOSD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for JOSD1 gene
    JOSD22  
    2 SIMAP similar genes for JOSD1 using alignment to 6 protein entries:     JOS1_HUMAN (see all proteins):
    KIAA0063    JOSD2

    JOSD1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for JOSD1
    PGOHUM00000245282


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for JOSD1 (see all 339)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1453636821,2
    --39081350(+) CAGTGC/TGGTAC 1 -- ds50010--------
    rs1491795501,2
    --39081471(+) CTATTC/TTGTCT 1 -- ds50010--------
    rs1442029661,2
    C--39081621(+) GAGAC-/ATATATG 1 -- ut310--------
    rs1430853441,2
    C--39081633(+) GAGTTG/TTCCAT 1 -- ut310--------
    rs1873967901,2
    --39081647(+) TAATAC/TTTGGT 1 -- ut310--------
    rs1931180041,2
    --39081806(+) GCCCTG/TGGGCA 1 -- ut310--------
    rs1150009581,2
    C,F--39081842(+) ACCAGA/GATTGG 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs1385851201,2
    --39082027(+) GTGGCC/TCCAAG 1 -- ut310--------
    rs57572431,2
    H--39082043(+) GCTTGT/AGACAA 1 -- ut31 ese34Minor allele frequency- A:0.00NS EA 418
    rs1123952951,2
    C,F--39082169(+) GACTGC/TGGCCA 1 -- ut311Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for JOSD1 (39081548 - 39097561 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for JOSD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv915067CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing JOSD1
    DNA2.0 Custom Variant and Variant Library Synthesis for JOSD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615323    OMIM disorders: --


    JOSD1 for disorders           About GeneDecksing


    Export disorders for JOSD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for JOSD1 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with JOSD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2, 3 Nomura N.... Tabata S. (DNA Res. 1994)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    4. Structural modeling of ataxin-3 reveals distant homology to adaptins. (PubMed id 12486728)1, 2 Albrecht M....Lengauer T. (Proteins 2003)
    5. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    6. JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosis. (PubMed id 23625928)2 Seki T.... Paulson H.L. (J. Biol. Chem. 2013)
    7. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    8. A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (Biochim. Biophys. Acta 2012)
    9. Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)1 Guo Z....Gao Y. (J. Proteome Res. 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9929 HGNC: 28953 AceView: KIAA0063 Ensembl:ENSG00000100221 euGenes: HUgn9929
    ECgene: JOSD1 H-InvDB: JOSD1

    (According to HUGE)
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    HUGE: KIAA0063

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for JOSD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for JOSD1 gene:
    Search GeneIP for patents involving JOSD1

    GeneCards and IP:
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