Aliases for JOSD1 Gene
External Ids for JOSD1 Gene
GeneCards Summary for JOSD1 Gene
JOSD1 (Josephin Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include omega peptidase activity. An important paralog of this gene is JOSD2.
UniProtKB/Swiss-Prot for JOSD1 Gene
Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves Lys-63-linked and Lys-48-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.