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Aliases for JMJD7-PLA2G4B Gene

Aliases for JMJD7-PLA2G4B Gene

  • JMJD7-PLA2G4B Readthrough 2 3 5
  • Jumonji Domain Containing 7-Phospholipase A2, Group IVB (Cytosolic) Read-Through 3
  • JMJD7-PLA2G4B Protein 3
  • CPLA2-Beta 3
  • HsT16992 3

External Ids for JMJD7-PLA2G4B Gene

Previous GeneCards Identifiers for JMJD7-PLA2G4B Gene

  • GC15P039910
  • GC15P042122
  • GC15P018968

Summaries for JMJD7-PLA2G4B Gene

Entrez Gene Summary for JMJD7-PLA2G4B Gene

  • This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013]

GeneCards Summary for JMJD7-PLA2G4B Gene

JMJD7-PLA2G4B (JMJD7-PLA2G4B Readthrough) is a Protein Coding gene. Among its related pathways are Circadian entrainment and Acyl chain remodelling of PC. GO annotations related to this gene include calcium ion binding and phospholipase activity. An important paralog of this gene is PLA2G4B.

Gene Wiki entry for JMJD7-PLA2G4B Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JMJD7-PLA2G4B Gene

Genomics for JMJD7-PLA2G4B Gene

Regulatory Elements for JMJD7-PLA2G4B Gene

Enhancers for JMJD7-PLA2G4B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around JMJD7-PLA2G4B on UCSC Golden Path with GeneCards custom track

Promoters for JMJD7-PLA2G4B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for JMJD7-PLA2G4B Gene

41,828,085 bp from pter
41,848,155 bp from pter
20,071 bases
Plus strand

Genomic View for JMJD7-PLA2G4B Gene

Genes around JMJD7-PLA2G4B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
JMJD7-PLA2G4B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for JMJD7-PLA2G4B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JMJD7-PLA2G4B Gene

Proteins for JMJD7-PLA2G4B Gene

  • Protein details for JMJD7-PLA2G4B Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein JMJD7-PLA2G4B
    Protein Accession:

    Protein attributes for JMJD7-PLA2G4B Gene

    81 amino acids
    Molecular mass:
    9403 Da
    Quaternary structure:
    No Data Available

neXtProt entry for JMJD7-PLA2G4B Gene

Protein Expression for JMJD7-PLA2G4B Gene

Post-translational modifications for JMJD7-PLA2G4B Gene

No Post-translational modifications

Other Protein References for JMJD7-PLA2G4B Gene

No data available for DME Specific Peptides for JMJD7-PLA2G4B Gene

Domains & Families for JMJD7-PLA2G4B Gene

Protein Domains for JMJD7-PLA2G4B Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with JMJD7-PLA2G4B: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for JMJD7-PLA2G4B Gene

Function for JMJD7-PLA2G4B Gene

genes like me logo Genes that share phenotypes with JMJD7-PLA2G4B: view

Animal Model Products

CRISPR Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for JMJD7-PLA2G4B Gene

Localization for JMJD7-PLA2G4B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for JMJD7-PLA2G4B Gene

Pathways & Interactions for JMJD7-PLA2G4B Gene

genes like me logo Genes that share pathways with JMJD7-PLA2G4B: view

Interacting Proteins for JMJD7-PLA2G4B Gene

Gene Ontology (GO) - Biological Process for JMJD7-PLA2G4B Gene


No data available for SIGNOR curated interactions for JMJD7-PLA2G4B Gene

Drugs & Compounds for JMJD7-PLA2G4B Gene

No Compound Related Data Available

Transcripts for JMJD7-PLA2G4B Gene

Unigene Clusters for JMJD7-PLA2G4B Gene

JMJD7-PLA2G4B readthrough:
Representative Sequences:

CRISPR Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for JMJD7-PLA2G4B Gene

No ASD Table

Relevant External Links for JMJD7-PLA2G4B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for JMJD7-PLA2G4B Gene

mRNA expression in normal human tissues for JMJD7-PLA2G4B Gene

Protein differential expression in normal tissues from HIPED for JMJD7-PLA2G4B Gene

This gene is overexpressed in Cervix (33.0) and Urine (32.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb and MOPED for JMJD7-PLA2G4B Gene

Protein tissue co-expression partners for JMJD7-PLA2G4B Gene

SOURCE GeneReport for Unigene cluster for JMJD7-PLA2G4B Gene:

genes like me logo Genes that share expression patterns with JMJD7-PLA2G4B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for JMJD7-PLA2G4B Gene

Orthologs for JMJD7-PLA2G4B Gene

This gene was present in the common ancestor of chordates.

Orthologs for JMJD7-PLA2G4B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia PLA2G4B 35
  • 84 (a)
(Canis familiaris)
Mammalia PLA2G4B 35
  • 81 (a)
(Mus musculus)
Mammalia Pla2g4b 35
  • 84 (a)
PLA2G4B 35
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 69 (a)
(Pan troglodytes)
Mammalia -- 35
  • 97 (a)
-- 35
  • 98 (a)
(Gallus gallus)
Aves -- 35
  • 46 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 46 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 23 (a)
-- 35
  • 19 (a)
Species where no ortholog for JMJD7-PLA2G4B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for JMJD7-PLA2G4B Gene

Gene Tree for JMJD7-PLA2G4B (if available)
Gene Tree for JMJD7-PLA2G4B (if available)

Paralogs for JMJD7-PLA2G4B Gene

Paralogs for JMJD7-PLA2G4B Gene

(1) SIMAP similar genes for JMJD7-PLA2G4B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with JMJD7-PLA2G4B: view

Variants for JMJD7-PLA2G4B Gene

Sequence variations from dbSNP and Humsavar for JMJD7-PLA2G4B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs773745185 -- 41,847,575(+) CCTCC(-/TCCGTCCCCTGTGCCTCT)CCAAA intron-variant
rs776996660 -- 41,847,569(+) CCCAC(-/ACCTCCTCCGTCCCCTGTGCCTCTCCAA)ACCTG intron-variant
rs747287338 -- 41,847,563(+) CAGTC(-/CCCCACACCTCCTCCGTCCCCTGTG)CCTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for JMJD7-PLA2G4B Gene

Variant ID Type Subtype PubMed ID
dgv2582n100 CNV gain 25217958
esv2760027 CNV loss 17122850
esv3636251 CNV loss 21293372
nsv1035998 CNV gain 25217958
nsv1038933 CNV gain 25217958
nsv1050892 CNV gain 25217958
nsv1506 CNV insertion 18451855
nsv517631 CNV loss 19592680
nsv9244 CNV gain 18304495
nsv952613 CNV deletion 24416366
nsv977704 CNV duplication 23825009

Variation tolerance for JMJD7-PLA2G4B Gene

Residual Variation Intolerance Score: 95.9% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for JMJD7-PLA2G4B Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for JMJD7-PLA2G4B Gene

Disorders for JMJD7-PLA2G4B Gene

Relevant External Links for JMJD7-PLA2G4B

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for JMJD7-PLA2G4B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for JMJD7-PLA2G4B Gene

Publications for JMJD7-PLA2G4B Gene

  1. Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes. (PMID: 16617059) Ghosh M. … Leslie C.C. (J. Biol. Chem. 2006) 3 22 65
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  3. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3 65
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 65
  5. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 65

Products for JMJD7-PLA2G4B Gene

Sources for JMJD7-PLA2G4B Gene

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