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Aliases for JMJD7 Gene

Aliases for JMJD7 Gene

  • Jumonji Domain Containing 7 2 3
  • Jumonji Domain-Containing Protein 7 4

External Ids for JMJD7 Gene

Previous GeneCards Identifiers for JMJD7 Gene

  • GC15U900840
  • GC15P039909
  • GC15P042121
  • GC15P018969

Summaries for JMJD7 Gene

Entrez Gene Summary for JMJD7 Gene

  • This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for JMJD7 Gene

JMJD7 (Jumonji Domain Containing 7) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JMJD7 Gene

Genomics for JMJD7 Gene

Regulatory Elements for JMJD7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for JMJD7 Gene

41,828,085 bp from pter
41,837,587 bp from pter
9,503 bases
Plus strand

Genomic View for JMJD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for JMJD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JMJD7 Gene

Proteins for JMJD7 Gene

  • Protein details for JMJD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    JmjC domain-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • A5D6V5
    • O95712
    • Q59GF9
    • Q8TB10
    • Q9UKV7

    Protein attributes for JMJD7 Gene

    316 amino acids
    Molecular mass:
    35932 Da
    Quaternary structure:
    No Data Available

neXtProt entry for JMJD7 Gene

Proteomics data for JMJD7 Gene at MOPED

Post-translational modifications for JMJD7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for JMJD7 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for JMJD7 Gene

Domains for JMJD7 Gene

Protein Domains for JMJD7 Gene


Suggested Antigen Peptide Sequences for JMJD7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • P0C870
  • Contains 1 JmjC domain.
genes like me logo Genes that share domains with JMJD7: view

No data available for Gene Families for JMJD7 Gene

Function for JMJD7 Gene

Gene Ontology (GO) - Molecular Function for JMJD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with JMJD7: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for JMJD7 Gene

Localization for JMJD7 Gene

Subcellular locations from

Jensen Localization Image for JMJD7 Gene COMPARTMENTS Subcellular localization image for JMJD7 gene
Compartment Confidence
cytosol 5
endosome 5
extracellular 5
mitochondrion 5
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for JMJD7 Gene

Pathways for JMJD7 Gene

SuperPathways for JMJD7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for JMJD7 Gene


No data available for Pathways by source for JMJD7 Gene

Transcripts for JMJD7 Gene

mRNA/cDNA for JMJD7 Gene

(1) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for JMJD7

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for JMJD7 Gene

No ASD Table

Relevant External Links for JMJD7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for JMJD7 Gene

mRNA expression in normal human tissues for JMJD7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for JMJD7 Gene

This gene is overexpressed in Brain - Cerebellum (4.3) and Brain - Cerebellar Hemisphere (4.1).

Protein differential expression in normal tissues for JMJD7 Gene

This gene is overexpressed in Heart (13.5), Cervix (9.8), Salivary gland (8.8), and Retina (7.4).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for JMJD7 Gene

genes like me logo Genes that share expressions with JMJD7: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Expression partners for JMJD7 Gene

Orthologs for JMJD7 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for JMJD7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia JMJD7 35
  • 89.03 (n)
  • 93.04 (a)
JMJD7 36
  • 93 (a)
(Canis familiaris)
Mammalia JMJD7 35
  • 88.82 (n)
  • 92.41 (a)
JMJD7 36
  • 86 (a)
(Mus musculus)
Mammalia Jmjd7 35
  • 85.23 (n)
  • 89.87 (a)
Jmjd7 16
Jmjd7 36
  • 90 (a)
(Pan troglodytes)
Mammalia JMJD7 35
  • 98.84 (n)
  • 97.78 (a)
-- 36
  • 98 (a)
-- 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Jmjd7 35
  • 85.44 (n)
  • 89.56 (a)
(Ornithorhynchus anatinus)
Mammalia JMJD7 36
  • 75 (a)
(Gallus gallus)
Aves JMJD7 35
  • 65.92 (n)
  • 70.51 (a)
JMJD7 36
  • 70 (a)
(Anolis carolinensis)
Reptilia JMJD7 36
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia jmjd7 35
  • 65.38 (n)
  • 67.85 (a)
(Danio rerio)
Actinopterygii jmjd7 35
  • 66.67 (n)
  • 65.7 (a)
jmjd7 36
  • 65 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007766 35
  • 52.51 (n)
  • 42.47 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10133 35
  • 53.79 (n)
  • 46.9 (a)
CG10133 36
  • 44 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G45880 35
  • 49.51 (n)
  • 42.3 (a)
(Oryza sativa)
Liliopsida Os09g0483600 35
  • 56.82 (n)
  • 47.69 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU03670 35
  • 45.5 (n)
  • 33.58 (a)
Species with no ortholog for JMJD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for JMJD7 Gene

Gene Tree for JMJD7 (if available)
Gene Tree for JMJD7 (if available)

Paralogs for JMJD7 Gene

Selected SIMAP similar genes for JMJD7 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with JMJD7: view

No data available for Paralogs for JMJD7 Gene

Variants for JMJD7 Gene

Sequence variations from dbSNP and Humsavar for JMJD7 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
VAR_027046 -
VAR_069392 -

Structural Variations from Database of Genomic Variants (DGV) for JMJD7 Gene

Variant ID Type Subtype PubMed ID
dgv740e1 CNV Complex 17122850
nsv904115 CNV Loss 21882294
nsv904116 CNV Loss 21882294
nsv517631 CNV Loss 19592680
dgv2364n71 CNV Loss 21882294
nsv904119 CNV Loss 21882294
dgv2365n71 CNV Loss 21882294
nsv9244 CNV Gain 18304495
nsv1506 CNV Insertion 18451855

Relevant External Links for JMJD7 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for JMJD7 Gene

Disorders for JMJD7 Gene

Relevant External Links for JMJD7

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for JMJD7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for JMJD7 Gene

Publications for JMJD7 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. Diagnostic exome sequencing in persons with severe intellectual disability. (PMID: 23033978) de Ligt J. … Vissers L.E. (N. Engl. J. Med. 2012) 4

Products for JMJD7 Gene

Sources for JMJD7 Gene

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