Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



JMJD4 Gene

protein-coding   GIFtS: 45
GCID: GC01M227918

Jumonji Domain Containing 4

  Search for JMJD4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Jumonji Domain Containing 41 2
Jumonji Domain-Containing Protein 42 3
JmjC Domain-Containing Protein 42

External Ids:    HGNC: 257241   Entrez Gene: 650942   Ensembl: ENSG000000816927   UniProtKB: Q9H9V93   

Export aliases for JMJD4 gene to outside databases

Previous GC identifers: GC01M224226 GC01M225985 GC01M198436


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for JMJD4 Gene:
JMJD4 (jumonji domain containing 4) is a protein-coding gene. An important paralog of this gene is JMJD6.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_167186.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the JMJD4 gene promoter:
         AREB6   STAT1   AML1a   POU2F1   POU2F1a   LUN-1   CUTL1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidJMJD4 promoter sequence
   Search Chromatin IP Primers for JMJD4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat JMJD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.13   Ensembl cytogenetic band:  1q42.13   HGNC cytogenetic band: 1q42.13

JMJD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
JMJD4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M227918:  view genomic region     (about GC identifiers)

Start:
227,918,126 bp from pter      End:
227,923,112 bp from pter
Size:
4,987 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: JMJD4_HUMAN, Q9H9V9 (See protein sequence)
Recommended Name: JmjC domain-containing protein 4  
Size: 463 amino acids; 52493 Da
Caution: It is uncertain whether Met-1 or Met-47 is the initiator
Sequence caution: Sequence=BAB14366.1; Type=Erroneous initiation; Sequence=CAI23067.1; Type=Erroneous initiation;
Secondary accessions: Q5TBZ1 Q5TBZ6 Q9H970
Alternative splicing: 2 isoforms:  Q9H9V9-1   Q9H9V9-2   

Explore the universe of human proteins at neXtProt for JMJD4: NX_Q9H9V9

Explore proteomics data for JMJD4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys153, Lys447
  • Modification sites at PhosphoSitePlus

  • See JMJD4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001154937.1  NP_075383.2  

    ENSEMBL proteins: 
     ENSP00000355720   ENSP00000387830  

    JMJD4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for JMJD4
    OriGene Custom MassSpec
    OriGene Custom Protein Services for JMJD4
    GenScript Custom Purified and Recombinant Proteins Services for JMJD4
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for JMJD4

     
    Search eBioscience for Proteins for JMJD4 

    JMJD4 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of JMJD4
    Browse R&D Systems for Antibodies
    OriGene Antibodies for JMJD4
    OriGene Custom Antibody Services for JMJD4
    Novus Biologicals JMJD4 Antibody
    Search for Antibodies for JMJD4 at Abcam
    Cloud-Clone Corp. Antibodies for JMJD4
    ThermoFisher Antibody for JMJD4
    LSBio Antibodies in human, mouse, rat for JMJD4

    JMJD4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for JMJD4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for JMJD4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for JMJD4
    Cloud-Clone Corp. CLIAs for JMJD4
    Search eBioscience for ELISAs for JMJD4 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR003347 JmjC_dom

    Graphical View of Domain Structure for InterPro Entry Q9H9V9

    ProtoNet protein and cluster: Q9H9V9

    UniProtKB/Swiss-Prot: JMJD4_HUMAN, Q9H9V9
    Similarity: Contains 1 JmjC domain


    Find genes that share domains with JMJD4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with JMJD4           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for JMJD4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for JMJD4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for JMJD4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for JMJD4

    miRNA
    Products:
        
    miRTarBase miRNAs that target JMJD4:
    hsa-mir-148b-3p (MIRT043597), hsa-mir-98-5p (MIRT027810)

    Block miRNA regulation of human, mouse, rat JMJD4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate JMJD4
    SwitchGear 3'UTR luciferase reporter plasmidJMJD4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for JMJD4
    Predesigned siRNA for gene silencing in human, mouse, rat JMJD4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for JMJD4

    Clone
    Products:
         
    OriGene clones in human, mouse for JMJD4 (see all 12)
    OriGene ORF clones in mouse, rat for JMJD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): JMJD4 (NM_001161465)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for JMJD4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat JMJD4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for JMJD4
    Browse ESI BIO Cell Lines and PureStem Progenitors for JMJD4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for JMJD4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    cytosol1
    extracellular1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for JMJD4
    Interactions:

        Search GeneGlobe Interaction Network for JMJD4

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for JMJD4 (ENSP000003557204) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    MLLT1ENSP000002526744STRING: ENSP00000252674
    MLLT3ENSP000003696954STRING: ENSP00000369695
    YEATS2ENSP000003069834STRING: ENSP00000306983
    YEATS4ENSP000002478434STRING: ENSP00000247843
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for JMJD4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for JMJD4 gene (2 alternative transcripts): 
    NM_001161465.1  NM_023007.2  

    Unigene Cluster for JMJD4:

    Jumonji domain containing 4
    Hs.555974  [show with all ESTs]
    Unigene Representative Sequence: NM_023007
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485807 ENST00000366758(uc001hrc.3 uc001hrb.3) ENST00000438896
    ENST00000480590 ENST00000465251
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat JMJD4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate JMJD4
    SwitchGear 3'UTR luciferase reporter plasmidJMJD4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for JMJD4
    Predesigned siRNA for gene silencing in human, mouse, rat JMJD4
    Clone
    Products:
         
    OriGene clones in human, mouse for JMJD4 (see all 12)
    OriGene ORF clones in mouse, rat for JMJD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): JMJD4 (NM_001161465)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for JMJD4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat JMJD4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for JMJD4
    OriGene qSTAR qPCR primer pairs in human, mouse for JMJD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat JMJD4
      QuantiTect SYBR Green Assays in human, mouse, rat JMJD4
      QuantiFast Probe-based Assays in human, mouse, rat JMJD4

    Additional mRNA sequence: 

    AK022579.1 AK023030.1 BC011928.2 BC109272.2 

    20 DOTS entries:

    DT.95160318  DT.100834440  DT.100834442  DT.95160338  DT.101984021  DT.97847177  DT.100756711  DT.100834424 
    DT.100834433  DT.40301445  DT.95160341  DT.75152596  DT.95160326  DT.121447836  DT.100649719  DT.100696655 
    DT.100840419  DT.121447553  DT.121447672  DT.121447735 

    Selected AceView cDNA sequences (see all 167):

    BU683775 AI190926 CR593629 BM662512 AI972516 CD557198 BX444534 BE269261 
    CA777733 BX482390 CR603747 AK026908 BE297279 BM835213 CA777470 BE464071 
    AI623217 BU184048 AW589974 AI199369 BP873258 BE277284 CA433609 BI768068 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for JMJD4    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c
    SP1:              -                                                   
    SP2:              -                       -                           
    SP3:                                                                  
    SP4:                                                                  


    ECgene alternative splicing isoforms for JMJD4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    JMJD4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAAGTGCTT
    JMJD4 Expression
    About this image


    JMJD4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Skeletal Muscle (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
     
     Somite (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
    JMJD4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    JMJD4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.555974
        Custom PCR Arrays for JMJD4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for JMJD4
    OriGene qSTAR qPCR primer pairs in human, mouse for JMJD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat JMJD4
    QuantiTect SYBR Green Assays in human, mouse, rat JMJD4
    QuantiFast Probe-based Assays in human, mouse, rat JMJD4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for JMJD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for JMJD4 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Jmjd41 , 5 jumonji domain containing 41, 5 78.21(n)1
    76.44(a)1
      11 (37.71 cM)5
    1949521  NM_178659.61  NP_848774.11 
     594500455 
    chicken
    (Gallus gallus)
    Aves JMJD41 jumonji domain containing 4 64.81(n)
    60.77(a)
      420400  NM_001030959.1  NP_001026130.1 
    lizard
    (Anolis carolinensis)
    Reptilia JMJD46
    jumonji domain containing 4
    58(a)
    1 ↔ 1
    GL343449.1(430572-441180)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia jmjd41 jumonji domain containing 4 62(n)
    57.77(a)
      100491509  XM_002939362.2  XP_002939408.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK401100.12   -- 70.76(n)    CK401100.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG72001 CG7200 50.38(n)
    39.94(a)
      35089  NM_136026.3  NP_609870.1 
    worm
    (Caenorhabditis elegans)
    Secernentea jmjd-46
    Protein JMJD-4, isoform a (jmjd-4) mRNA, complete ...
    30(a)
    1 ↔ 1
    III(10332455-10334069) WBGene00011563
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G630801 AT5G63080 46.49(n)
    37.65(a)
      836428  NM_125702.3  NP_201113.2 
    rice
    (Oryza sativa)
    Liliopsida Os01g05469001 Os01g0546900 48.14(n)
    38.31(a)
      4326179  NM_001049820.1  NP_001043285.2 


    ENSEMBL Gene Tree for JMJD4 (if available)
    TreeFam Gene Tree for JMJD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for JMJD4 gene
    JMJD62  

    Find genes that share paralogs with JMJD4           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for JMJD4
    PGOHUM00000238177


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    4 SNPs for JMJD4    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30879081,2,4
    ----see VAR_0329012 mis40--------
    rs22959941,2,4
    ----see VAR_0329002 mis40--------
    rs345608981,2,4
    ----see VAR_0328992 mis40--------
    rs74192381,2,4
    ----see VAR_0328982 mis40--------

    HapMap Linkage Disequilibrium report for JMJD4 (227918126 - 227923112 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for JMJD4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv873249CNV Loss21882294
    nsv515496CNV Loss19592680
    esv32853CNV Gain17666407
    nsv826908CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing JMJD4
    DNA2.0 Custom Variant and Variant Library Synthesis for JMJD4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for JMJD4 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with JMJD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (Nature 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 65094 HGNC: 25724 AceView: FLJ12517 Ensembl:ENSG00000081692 euGenes: HUgn65094
    ECgene: JMJD4 H-InvDB: JMJD4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for JMJD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for JMJD4 gene:
    Search GeneIP for patents involving JMJD4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of JMJD4
     Browse Small Molecules at EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for JMJD4   OriGene RNAi products in human, mouse, rat for JMJD4  
     OriGene qPCR primer pairs and template standards for JMJD4   OriGene Protein Over-expression Lysate for JMJD4  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for JMJD4  
     OriGene qSTAR qPCR primer pairs in human, mouse for JMJD4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for JMJD4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for JMJD4   OriGene Custom Protein Services for JMJD4  

     
     
     Block miRNA regulation of human, mouse, rat JMJD4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing JMJD4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat JMJD4 Predesigned siRNA for gene silencing in human, mouse, rat JMJD4
     QuantiFast Probe-based Assays in human, mouse, rat JMJD4 QuantiTect SYBR Green Assays in human, mouse, rat JMJD4
     Custom PCR Arrays for JMJD4 Search Chromatin IP Primers for JMJD4
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat JMJD4  Search GeneGlobe Interaction Network for JMJD4
     Regulatory tfbs in JMJD4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for JMJD4 GenScript cDNA clones with any tag delivered in your preferred vector for JMJD4
     GenScript Custom Assay Services for JMJD4 GenScript Custom overexpressing Cell Line Services for JMJD4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for JMJD4
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     JMJD4 antibodies
     Search for Antibodies for JMJD4 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for JMJD4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for JMJD4
     Antibodies for JMJD4
     ELISAs for JMJD4
     CLIAs for JMJD4



     Browse ESI BIO Cell Lines and PureStem Progenitors for JMJD4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for JMJD4
     SwitchGear 3'UTR luciferase reporter plasmids for JMJD4
     SwitchGear Promoter luciferase reporter plasmids for JMJD4
     ThermoFisher Antibody for JMJD4
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat JMJD4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for JMJD4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for JMJD4
     LSBio Antibodies in human, mouse, rat for JMJD4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for JMJD4
      Search eBioscience for proteins for JMJD4
      Search eBioscience for elisas for JMJD4
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      JMJD4 gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4