Aliases for JMJD1C Gene
External Ids for JMJD1C Gene
Previous HGNC Symbols for JMJD1C Gene
Previous GeneCards Identifiers for JMJD1C Gene
GeneCards Summary for JMJD1C Gene
JMJD1C (Jumonji Domain Containing 1C) is a Protein Coding gene. Diseases associated with JMJD1C include central nervous system germinoma and persistent hyperplastic primary vitreous. Among its related pathways are Hemostasis and Transcriptional misregulation in cancer. GO annotations related to this gene include thyroid hormone receptor binding and dioxygenase activity. An important paralog of this gene is HR.
UniProtKB/Swiss-Prot for JMJD1C Gene
Probable histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).