V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

KDM5B Gene

protein-coding GIFtS: 46

GC01M200965

lysine (K)-specific demethylase 5B
(Previous names: Jumonji, AT rich interactive domain 1B (RBP2-like), jumonji, AT rich interactive domain 1B )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: JARID1B)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CT31 ^¹, ², ³
EC 1.14.11.- ^³
FLJ10538 ^²
FLJ12459 ^²
FLJ12491 ^²
FLJ16281 ^²
FLJ23670 ^²
JARID1B ^², ³
OTTHUMP00000038815 ^²
PLU-1 ^¹, ², ³
PLU1 ^³
PUT1 ^²
RBBP2H1 ^³
RBBP2H1A ^¹, ²
RBP2-H1 ^³
RBP2-like ^²

Descriptions
Cancer/testis antigen 31 ^², ³
Histone demethylase JARID1B ^³
Jumonji, AT rich interactive domain 1B (RBP2-like) ^¹
Jumonji/ARID domain-containing protein 1B ^³
Retinoblastoma-binding protein 2 homolog 1 ^³
jumonji, AT rich interactive domain 1B ^¹, ²
lysine (K)-specific demethylase 5B ^²
lysine-specific demethylase 5B ^¹
putative DNA/chromatin binding motif ^²
retinoblastoma-binding protein 2, homolog 1A ^²

External Ids
HGNC: 18039¹
Entrez Gene: 10765²
UniProtKB: Q9UGL1³

Search outside databases for aliases for KDM5B gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: KDM5B_HUMAN, Q9UGL1

Function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central

role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates

trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor

for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor

suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma

Gene Wiki entry for KDM5B (JARID1B)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32.1

KDM5B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M200965: (about GC identifiers)

Start:	200,963,155 bp from pter
End:	201,044,172 bp from pter
Size:	81,018 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: KDM5B_HUMAN, Q9UGL1 (See protein sequence)

Recommended Name: Lysine-specific demethylase 5B

Size: 1544 amino acids; 175645 Da

Cofactor: Fe(2+) (By similarity)

Subunit: Interacts with FOXG1B, PAX9, MYC, MYCN and RB1. Interacts with HDAC1, HDAC4, HDAC5 and

HDAC7 (By similarity)

Subcellular location: Nucleus

Secondary accessions: O95811 Q15752 Q9Y3Q5

Alternative splicing: 2 isoforms: Q9UGL1-1 Q9UGL1-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_006609.3
Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (KDM5B / PLU1 / Jarid1B)
	Human Recombinant Proteins from Abnova (JARID1B)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	TAS	10336460 12657635

About this table

Antibodies for KDM5B:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for KDM5B
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for KDM5B (JARID1B)
	Antibodies from Abcam (KDM5B / PLU1 / Jarid1B), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (JARID1B)
	Novus Biologicals Antibodies for JARID1B

Assays for KDM5B:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UGL1

ProtoNet protein and cluster: Q9UGL1

5 Blocks protein families:

IPB001606 ARID (AT-rich interaction domain) protein

IPB003347 Transcription factor jumonji

IPB003349 Transcription factor jumonji

IPB004198 Zn-finger

IPB013637 PLU-1-like

UniProtKB/Swiss-Prot: KDM5B_HUMAN, Q9UGL1

Domain: Both the JmjC domain and the JmjN domain are required for enzymatic activity

Domain: The 2 first PHD-type zinc finger domains are required for transcription repression activity

Similarity: Belongs to the JARID1 histone demethylase family

Similarity: Contains 1 ARID domain

Similarity: Contains 1 JmjC domain

Similarity: Contains 1 JmjN domain

Similarity: Contains 3 PHD-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KDM5B)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (JARID1B)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006618

Applied Biosystems Silencer® siRNAs for KDM5B

Sigma-Aldrich siRNA and siRNA Panels for KDM5B

Sigma-Aldrich shRNA for KDM5B

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006618
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006618
untagged cDNA clone in CMV expression vector: NM_006618

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006618

UniProtKB/Swiss-Prot: KDM5B_HUMAN, Q9UGL1

Function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central

role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates

trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor

for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor

suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma

Enzyme Number (IUBMB): EC 1.14.11.-

5/8 Gene Ontology (GO) molecular function terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	10336460
GO:0005506	iron ion binding	IEA	--
GO:0005515	protein binding	IPI	12657635
GO:0008270	zinc ion binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for KDM5B (Your Favorite Gene powered by Ingenuity)

Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency

GeneDecks KDM5B for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for KDM5B

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0016568	chromatin modification	IEA	--
GO:0045892	negative regulation of transcription, DNA-dependent	IDA	12657635
GO:0055114	oxidation reduction	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for KDM5B

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KDM5B)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (JARID1B)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006618

Sigma-Aldrich siRNA and siRNA Panels for KDM5B

Sigma-Aldrich shRNA for KDM5B

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006618

REFSEQ mRNAs for KDM5B gene:

NM_006618.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006618

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006618
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006618
                                 untagged cDNA clone in CMV expression vector: NM_006618

Additional cDNA sequence:

AB015348.1 AF087481.1 AJ132440.1 AJ243706.1 AK001400.1 AK022521.1 AK022553.1 AK074250.1

AK122752.1 AK125746.1 AL133040.1 AL133048.1 AL133072.1 AL137622.1 AL833515.1 CR610637.1

18 DOTS entries:

DT.97857065 DT.449384 DT.101963351 DT.97770938 DT.121434552 DT.101967997 DT.97810559 DT.91804138

DT.121434559 DT.121434585 DT.92008652 DT.120304 DT.121434525 DT.121434554 DT.121434565 DT.121434582

DT.92384997 DT.95200889

24/359 AceView cDNA sequences (see all 359 ):

BM702957 BQ637269 AI026894 AL704530 W72258 BX104183 BF000575 BM985272

AU149588 AU132575 BM998212 AI352104 AW151255 Z39493 BF901260 AI005463

AA948108 AA630339 CB133686 CA450574 AI751550 BF594529 BQ222747 BE550346

Unigene Cluster for KDM5B:

Lysine (K)-specific demethylase 5B

Hs.443650 [show with all ESTs]

Unigene Representative Sequence: AJ243706

GeneLoc Exon Structure

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KDM5B expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KDM5B

¹ / ²

9 probe-sets matching KDM5B gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39713_at²	U95-A	2	1.00	0.50	1.00	1.00	--	--	--	--	--
201548_s_at²	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
211202_s_at²	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
201547_at²	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
201549_x_at²	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
201548_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
211202_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
201547_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
201549_x_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks KDM5B for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TACAGCATTA

SOURCE GeneReport for Unigene cluster: Hs.443650
UniProtKB/Swiss-Prot: KDM5B_HUMAN, Q9UGL1
Tissue specificity: Ubiquitously expressed, with highest levels in testis. Down-regulated in
melanoma and gllioblastoma. Up-regulated in breast cancer (at protein level)

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KDM5B gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	JARID1B¹	--	jumonji, AT rich interactive domain 1B	93.03(n) 96.49(a)	479999 XM_537122.2 XP_537122.2
chimpanzee (Pan troglodytes)	JARID1B¹	--	jumonji, AT rich interactive domain 1B	99.37(n) 99.59(a)	457630 XM_514104.2 XP_514104.2
cow (Bos taurus)	JARID1B¹	--	jumonji, AT rich interactive domain 1B	87.29(n) 91.94(a)	540633 XM_612405.3 XP_612405.3
rat (Rattus norvegicus)	Jarid1b¹	--	jumonji, AT rich interactive domain 1B	88.56(n) 93.98(a)	304809 XM_239761.4 XP_239761.3
mouse (Mus musculus)	Kdm5b⁵ Jarid1b¹	1 (72.00 cM)⁵	lysine (K)-specific demethylase 5B⁵ jumonji, AT rich interactive domain 1B (Rbp2 like)¹	88.88(n)¹ 94.11(a)¹	75605¹ NM_152895.1¹ NP_690855.1¹ AA220427⁵ AA645519⁵ (see all 32)

About this table Species with no ortholog for KDM5B

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/498 NCBI SNPs in KDM5B are shown (see all 498 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 121)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs4348778^1,2	A,C,F,H	200962870(+)	`TTGTGC/TTTACT`	1	--	ng5¹		4	EU EA WA	418
	rs10920464^1,2	A,C,F,H	200964170(+)	`ACACAC/GTGTTT`	1	--	ut3¹		4	EU EA WA	420
	rs4245713^1,2	C,F,H	201044884(+)	`GGGGCA/GAAAGA`	1	--	ng3¹		12	EU EA WA	1256
	rs10494837^1,2	C,F,H	200963958(+)	`TGTTAG/AGACGA`	1	--	ut3¹		12	NS NA EU EA WA	666
	rs10494836^1,2	C,F,H	200963501(+)	`ATTCAC/TAAGTC`	1	--	ut3¹		12	NS NA EU EA WA	666
	rs12126539^1,2	H	200964256(+)	`AGTCTA/CCCAGG`	1	--	ut3¹		4	EU EA WA	420
	rs1892164^1,2	A,C,F,H,O	200984825(+)	`TCATCA/GTGGGA`	1	H/H	syn¹		8	MN NA EU EA WA	736
	rs3196669^1,2	A,C,F,H,O	200999861(-)	`ACAACA/GGAAGC`	1	T/T	syn¹		7	EU EA WA NA	558
	rs1141108^1,2	A,C,F,H	200981907(-)	`CCTTAT/CAAATA`	1	Y/Y	syn¹		5	MN EU EA WA	596
	rs1141109^1,2	C,F,H	200972078(-)	`ATCCCG/CGTACA`	1	P/P	syn¹		8	EU EA WA	838

About this table

HapMap Linkage Disequilibrium images for KDM5B (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605393

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/23 PubMed articles for KDM5B gene (see all 23 ):

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. (PubMed id 17363312)^{3, 4} Yamane K.... Zhang Y. (2007)
Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. (PubMed id 17373667)^{3, 4} Barrett A.... Taylor-Papadimitriou J. (2007)
Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9. (PubMed id 12657635)^{3, 4} Tan K....Freemont P.S. (2003)
PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen? (PubMed id 12237901)^{3, 4} Barrett A.... Taylor-Papadimitriou J. (2002)
Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs. (PubMed id 11483573)^{2, 3} Lahoud M.H....Kola I. (2001)
Dynamics of the Mrf-2 DNA-binding domain free and in complex with DNA. (PubMed id 11478881)^{2, 3} Zhu L....Chen Y. (2001)
Isolation and chromosomal localization of a new human retinoblastoma binding protein 2 homologue 1a (RBBP2H1A). (PubMed id 10878660)^{3, 4} Kashuba V.... Zabarovsky E. (2000)
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. (PubMed id 10336460)^{3, 4} Lu P.J....Taylor-Papadimitriou J. (1999)
RBP2-H1/JARID1B is a transcriptional regulator with a tumor suppressive potential in melanoma cells. (PubMed id 17973255)³ Roesch A....Vogt T. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10765	HGNC: 18039	AceView: JARID1B	euGenes: HUgn10765	ECgene: KDM5B
H-InvDB: KDM5B

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KDM5B
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KDM5B:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KDM5B-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KDM5B		Antibodies for KDM5B
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KDM5B		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (JARID1B)
	Antibodies (JARID1B)
	Chimera RNAi (JARID1B)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for KDM5B (JARID1B)

	Recombinant Proteins (KDM5B / PLU1 / Jarid1B)
	Antibodies (KDM5B / PLU1 / Jarid1B)

Search OriGene for KDM5B

Search Tocris compounds for KDM5B

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for JARID1B

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
KDM5B Gene at Home site.
Version 2.41.1
server5.xennexinc.com

KDM5B Gene

protein-coding GIFtS: 46

Aliases &
Descriptions
for KDM5B

Summaries
for KDM5B

Genomic Location
for KDM5B

Proteins
for KDM5B

Protein Domains/
Families
for KDM5B

Gene Function
for KDM5B

Pathways & Interactions
for KDM5B

Drugs & Compounds
for KDM5B

Transcripts
for KDM5B

Expression
for KDM5B

Orthologs
for KDM5B

Paralogs
for KDM5B

SNPs/Variants
for KDM5B

Disorders & Mutations
for KDM5B

Medical News
for KDM5B

Publications
for KDM5B

Search for KDM5B

Genome Databases showing KDM5B

Other Databases showing KDM5B

Specialized Databases showing KDM5B

Licensable Technologies
for KDM5B

Services
for KDM5B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KDM5B (Gene Symbol)
CT31
EC 1.14.11.-
FLJ10538
FLJ12459
FLJ12491
FLJ16281
FLJ23670
JARID1B
OTTHUMP00000038815
PLU-1
PLU1
PUT1
RBBP2H1
RBBP2H1A
RBP2-H1
RBP2-like
Cancer/testis antigen 31
Histone demethylase JARID1B
Jumonji, AT rich interactive domain 1B (RBP2-like)
Jumonji/ARID domain-containing protein 1B
Retinoblastoma-binding protein 2 homolog 1
jumonji, AT rich interactive domain 1B
lysine (K)-specific demethylase 5B
lysine-specific demethylase 5B
putative DNA/chromatin binding motif
retinoblastoma-binding protein 2, homolog 1A

KDM5B Gene

protein-coding GIFtS: 46

Aliases & Descriptionsfor KDM5B

Summariesfor KDM5B

Genomic Locationfor KDM5B

Proteinsfor KDM5B

Protein Domains/Familiesfor KDM5B

Gene Functionfor KDM5B

Pathways & Interactionsfor KDM5B

Drugs & Compoundsfor KDM5B

Transcriptsfor KDM5B

Expression for KDM5B

Orthologsfor KDM5B

Paralogsfor KDM5B

SNPs/Variantsfor KDM5B

Disorders & Mutationsfor KDM5B

Medical Newsfor KDM5B

Publicationsfor KDM5B

Search for KDM5B

Genome Databases showing KDM5B

Other Databases showing KDM5B

Specialized Databases showing KDM5B

Licensable Technologiesfor KDM5B

Servicesfor KDM5B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KDM5B

Summaries
for KDM5B

Genomic Location
for KDM5B

Proteins
for KDM5B

Protein Domains/
Families
for KDM5B

Gene Function
for KDM5B

Pathways & Interactions
for KDM5B

Drugs & Compounds
for KDM5B

Transcripts
for KDM5B

Expression
for KDM5B

Orthologs
for KDM5B

Paralogs
for KDM5B

SNPs/Variants
for KDM5B

Disorders & Mutations
for KDM5B

Medical News
for KDM5B

Publications
for KDM5B

Licensable Technologies
for KDM5B

Services
for KDM5B