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Aliases for JAKMIP2 Gene

Aliases for JAKMIP2 Gene

  • Janus Kinase And Microtubule Interacting Protein 2 2 3
  • JAMIP2 3 4 6
  • NECC1 3 4 6
  • Neuroendocrine Long Coiled-Coil Protein 1 3 4
  • CTCL Tumor Antigen HD-CL-04 3 4
  • KIAA0555 4 6
  • Janus Kinase And Microtubule-Interacting Protein 2 3
  • Jak And Microtubule Interacting Protein 2 3

External Ids for JAKMIP2 Gene

Previous GeneCards Identifiers for JAKMIP2 Gene

  • GC05M146949
  • GC05M142117

Summaries for JAKMIP2 Gene

Entrez Gene Summary for JAKMIP2 Gene

  • The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

GeneCards Summary for JAKMIP2 Gene

JAKMIP2 (Janus Kinase And Microtubule Interacting Protein 2) is a Protein Coding gene. GO annotations related to this gene include microtubule binding and kinase binding. An important paralog of this gene is JAKMIP3.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JAKMIP2 Gene

Genomics for JAKMIP2 Gene

Regulatory Elements for JAKMIP2 Gene

Genomic Location for JAKMIP2 Gene

147,585,439 bp from pter
147,782,848 bp from pter
197,410 bases
Minus strand

Genomic View for JAKMIP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for JAKMIP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JAKMIP2 Gene

Proteins for JAKMIP2 Gene

  • Protein details for JAKMIP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Janus kinase and microtubule-interacting protein 2
    Protein Accession:
    Secondary Accessions:
    • A4ZZA7
    • A8K5G5
    • B4DSG0
    • G5E9Y0
    • O60302
    • Q548S1

    Protein attributes for JAKMIP2 Gene

    810 amino acids
    Molecular mass:
    94934 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA25481.2; Type=Frameshift; Positions=805; Evidence={ECO:0000305};

    Alternative splice isoforms for JAKMIP2 Gene


neXtProt entry for JAKMIP2 Gene

Proteomics data for JAKMIP2 Gene at MOPED

Post-translational modifications for JAKMIP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for JAKMIP2 Gene

Antibody Products

No data available for DME Specific Peptides for JAKMIP2 Gene

Domains for JAKMIP2 Gene

Protein Domains for JAKMIP2 Gene


Suggested Antigen Peptide Sequences for JAKMIP2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the JAKMIP family.
  • Belongs to the JAKMIP family.
genes like me logo Genes that share domains with JAKMIP2: view

No data available for Gene Families for JAKMIP2 Gene

Function for JAKMIP2 Gene

Gene Ontology (GO) - Molecular Function for JAKMIP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008017 microtubule binding IEA --
GO:0019900 kinase binding IEA --
genes like me logo Genes that share ontologies with JAKMIP2: view

Animal Model Products

CRISPR Products

miRNA for JAKMIP2 Gene

miRTarBase miRNAs that target JAKMIP2

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for JAKMIP2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for JAKMIP2 Gene

Localization for JAKMIP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for JAKMIP2 Gene

Golgi apparatus.

Subcellular locations from

Jensen Localization Image for JAKMIP2 Gene COMPARTMENTS Subcellular localization image for JAKMIP2 gene
Compartment Confidence
golgi apparatus 5
nucleus 3
cytosol 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for JAKMIP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IDA --
genes like me logo Genes that share ontologies with JAKMIP2: view

Pathways for JAKMIP2 Gene

SuperPathways for JAKMIP2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for JAKMIP2 Gene


No data available for Pathways by source for JAKMIP2 Gene

Transcripts for JAKMIP2 Gene

Unigene Clusters for JAKMIP2 Gene

Janus kinase and microtubule interacting protein 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for JAKMIP2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for JAKMIP2 Gene

No ASD Table

Relevant External Links for JAKMIP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for JAKMIP2 Gene

mRNA expression in normal human tissues for JAKMIP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for JAKMIP2 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (4.5) and Brain - Cerebellum (4.0).

Protein differential expression in normal tissues for JAKMIP2 Gene

This gene is overexpressed in Ovary (67.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for JAKMIP2 Gene

SOURCE GeneReport for Unigene cluster for JAKMIP2 Gene Hs.744926

mRNA Expression by UniProt/SwissProt for JAKMIP2 Gene

Tissue specificity: Highly expressed in brain, moderately expressed in thymus, spleen and lung, and weakly expressed in kidney, liver and peripheral blood lymphocytes. Also expressed in adrenal and pituitary glands, as well as testis.
genes like me logo Genes that share expressions with JAKMIP2: view

Expression partners for JAKMIP2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

Orthologs for JAKMIP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for JAKMIP2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia JAKMIP2 35
  • 94.19 (n)
  • 99.63 (a)
  • 98 (a)
(Canis familiaris)
Mammalia JAKMIP2 35
  • 94.84 (n)
  • 99.51 (a)
  • 100 (a)
(Mus musculus)
Mammalia Jakmip2 35
  • 90.57 (n)
  • 99.27 (a)
Jakmip2 16
Jakmip2 36
  • 97 (a)
(Pan troglodytes)
Mammalia JAKMIP2 35
  • 99.63 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Jakmip2 35
  • 90.88 (n)
  • 99.13 (a)
(Monodelphis domestica)
Mammalia JAKMIP2 36
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia JAKMIP2 36
  • 95 (a)
(Gallus gallus)
Aves JAKMIP2 35
  • 82.64 (n)
  • 94.39 (a)
  • 92 (a)
(Anolis carolinensis)
Reptilia JAKMIP2 36
  • 91 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia jakmip2 35
  • 77.56 (n)
  • 89.27 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8504 35
(Danio rerio)
Actinopterygii jakmip2 35
  • 70.7 (n)
  • 81.07 (a)
jakmip2 36
  • 77 (a)
Species with no ortholog for JAKMIP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for JAKMIP2 Gene

Gene Tree for JAKMIP2 (if available)
Gene Tree for JAKMIP2 (if available)

Paralogs for JAKMIP2 Gene

Paralogs for JAKMIP2 Gene

(2) SIMAP similar genes for JAKMIP2 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with JAKMIP2: view

Variants for JAKMIP2 Gene

Sequence variations from dbSNP and Humsavar for JAKMIP2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs32204 -- 147,783,357(+) TTTCC(A/G)GCTAC upstream-variant-2KB
rs994025 -- 147,773,322(+) ACAAG(A/G)CTATG intron-variant
rs1016104 -- 147,759,166(+) TATCA(A/G)TGTTA intron-variant
rs1344786 -- 147,710,636(+) TATAT(A/G)TGAAA intron-variant
rs1347141 -- 147,689,221(+) gccaa(A/C)gagag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for JAKMIP2 Gene

Variant ID Type Subtype PubMed ID
nsv5056 CNV Insertion 18451855
esv2454562 CNV Insertion 19546169

Relevant External Links for JAKMIP2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for JAKMIP2 Gene

Disorders for JAKMIP2 Gene

Relevant External Links for JAKMIP2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for JAKMIP2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for JAKMIP2 Gene

Publications for JAKMIP2 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  2. Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins. (PMID: 17572408) Cruz-Garcia D. … Malagon M.M. (FEBS Lett. 2007) 3 4
  3. SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma. (PMID: 14996095) Hartmann T.B. … Eichmueller S. (Br. J. Dermatol. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations. (PMID: 19845895) Koskinen L.L. … Saavalainen P. (Tissue Antigens 2009) 3 48

Products for JAKMIP2 Gene

Sources for JAKMIP2 Gene

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