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JAKMIP1 Gene

protein-coding   GIFtS: 52
GCID: GC04M005962

Janus Kinase And Microtubule Interacting Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Janus Kinase And Microtubule Interacting Protein 11 2     Jak And Microtubule Interacting Protein 12
JAMIP12 3 5     Janus Kinase And Microtubule-Interacting Protein 12
MARLIN12 3 5     marlin-12
Multiple Alpha-Helices And RNA-Linker Protein 12 3     Multiple Coiled-Coil GABABR1-Binding Protein2
GABA-B Receptor-Binding Protein2 3     GABABRBP3
Gababrbp2     Marlin-13

External Ids:    HGNC: 264601   Entrez Gene: 1527892   Ensembl: ENSG000001529697   OMIM: 6111955   UniProtKB: Q96N163   

Export aliases for JAKMIP1 gene to outside databases

Previous GC identifer: GC04M006106


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for JAKMIP1 Gene:
JAKMIP1 (janus kinase and microtubule interacting protein 1) is a protein-coding gene. Diseases associated with JAKMIP1 include crohn's disease, and breast and colorectal cancer. GO annotations related to this gene include kinase binding and RNA binding. An important paralog of this gene is JAKMIP3.

UniProtKB/Swiss-Prot: JKIP1_HUMAN, Q96N16
Function: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B
receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_006051.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the JAKMIP1 gene promoter:
         AhR   Spz1   AML1a   p300   AP-4   Arnt   AREB6   NF-Y   CBF(2)   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidJAKMIP1 promoter sequence
   Search Chromatin IP Primers for JAKMIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat JAKMIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.1   Ensembl cytogenetic band:  4p16.1   HGNC cytogenetic band: 4p16.1

JAKMIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
JAKMIP1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M005962:  view genomic region     (about GC identifiers)

Start:
6,027,926 bp from pter      End:
6,202,318 bp from pter
Size:
174,393 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: JKIP1_HUMAN, Q96N16 (See protein sequence)
Recommended Name: Janus kinase and microtubule-interacting protein 1  
Size: 626 amino acids; 73209 Da
Subunit: Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2
Caution: Was originally (PubMed:14718537) thought to bind single-stranded RNA molecules and regulate GABA-B
receptor expression
Sequence caution: Sequence=BAC05325.1; Type=Erroneous termination; Positions=285; Note=Translated as Arg;
Sequence=BAC05325.1; Type=Erroneous translation; Note=Wrong choice of CDS;
Secondary accessions: A6H2J2 A6H2J3 A6H2J4 A6H2J5 A8MTK6 B8ZZR7 D3DVT0 Q86Y69 Q8N7G3
Alternative splicing: 6 isoforms:  Q96N16-1   Q96N16-2   Q96N16-3   Q96N16-4   Q96N16-5   Q96N16-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for JAKMIP1: NX_Q96N16

Explore proteomics data for JAKMIP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See JAKMIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001092903.1  NP_653321.1  

    ENSEMBL proteins: 
     ENSP00000386711   ENSP00000387042   ENSP00000422004   ENSP00000282924   ENSP00000386925  
     ENSP00000386745  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR024836 JAKMIP

    Graphical View of Domain Structure for InterPro Entry Q96N16

    ProtoNet protein and cluster: Q96N16

    UniProtKB/Swiss-Prot: JKIP1_HUMAN, Q96N16
    Similarity: Belongs to the JAKMIP family


    JAKMIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: JKIP1_HUMAN, Q96N16
    Function: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B
    receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IDA14718537
    GO:0005515protein binding IPI17500595
    GO:0008017microtubule binding IEA--
    GO:0019894kinesin binding IEA--
    GO:0019900kinase binding IEA--
         
    JAKMIP1 for ontologies           About GeneDecksing


    Animal Models:
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    hsa-mir-335-5p (MIRT018896)

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    Selected qRT-PCR Assays for microRNAs that regulate JAKMIP1 (see all 32):
    hsa-miR-3910 hsa-miR-34b* hsa-miR-25 hsa-miR-301a hsa-miR-519a hsa-miR-449a hsa-miR-124 hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidJAKMIP1 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    JKIP1_HUMAN, Q96N16: Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the
    microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in
    granules. Localizes to the tail and to a lower extent to the head of sperm cells
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol2
    peroxisome2
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005874microtubule IEA--
    GO:0019898extrinsic component of membrane IDA14718537
    GO:0030529ribonucleoprotein complex IDA14718537

    JAKMIP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for JAKMIP1 About    
    See pathways by source

    SuperPathContained pathways About
    1Integrated Breast Cancer Pathway
    Integrated Breast Cancer Pathway


    1 BioSystems Pathway for JAKMIP1
        Integrated Breast Cancer Pathway



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for JAKMIP1
    Interactions:

        GeneGlobe Interaction Network for JAKMIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for JAKMIP1 (Q96N163 ENSP000003867114) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000232632Q9UBS53, ENSP000003880354I2D: score=2 STRING: ENSP00000388035
    GABBR1Q9UBS53, ENSP000003662334I2D: score=2 STRING: ENSP00000366233
    ENSG00000206466Q9UBS53I2D: score=2 
    ENSG00000206511Q9UBS53I2D: score=2 
    ENSG00000232569Q9UBS53I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--
    GO:0050890cognition IMP17519220

    JAKMIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for JAKMIP1 (JKIP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for JAKMIP1 gene (2 alternative transcripts): 
    NM_001099433.1  NM_144720.3  

    Unigene Cluster for JAKMIP1:

    Janus kinase and microtubule interacting protein 1
    Hs.479066  [show with all ESTs]
    Unigene Representative Sequence: NM_001099433
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409021(uc010idb.1 uc010idd.1) ENST00000409371(uc010idc.1)
    ENST00000473053(uc010ide.3) ENST00000282924(uc003giv.4) ENST00000409831(uc003giu.4 uc011bwc.2)
    ENST00000410077 ENST00000457227
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate JAKMIP1 (see all 32):
    hsa-miR-3910 hsa-miR-34b* hsa-miR-25 hsa-miR-301a hsa-miR-519a hsa-miR-449a hsa-miR-124 hsa-miR-7-1*
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      QuantiTect SYBR Green Assays in human, mouse, rat JAKMIP1
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    Additional mRNA sequence: 

    AK056126.1 AK098536.1 AK124718.1 AK294356.1 AK295339.1 AK307983.1 AM412307.1 AM412308.1 
    AM412309.1 AM412310.1 AY382340.1 BC026343.1 BC047075.1 

    6 DOTS entries:

    DT.445810  DT.92020668  DT.101975859  DT.100020164  DT.91977808  DT.95360916 

    Selected AceView cDNA sequences (see all 31):

    BQ639074 AK098536 BU617552 Z44031 NM_144720 AL525796 AW954559 AK056126 
    AY382340 BM675261 BP429586 BM689820 BM685608 AL525757 BG705618 BI668982 
    AK124718 BC047075 R42780 AW157571 BC026343 BM695429 BM714077 H08055 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for JAKMIP1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15
    SP1:        -     -                                                                                 
    SP2:              -                                                                                 
    SP3:                    -     -                                               -                     


    ECgene alternative splicing isoforms for JAKMIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    JAKMIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    JAKMIP1 Expression
    About this image


    JAKMIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Blood Brain Barrier
     
     Brain (Nervous System)
             Mature Endothelial Cells Blood Brain Barrier
     
     Ovary (Reproductive System)
    JAKMIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    JAKMIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.479066

    UniProtKB/Swiss-Prot: JKIP1_HUMAN, Q96N16
    Tissue specificity: Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2,
    isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected
    in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for JAKMIP1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Jakmip11 , 5 janus kinase and microtubule interacting protein 11, 5 87.49(n)1
    95.21(a)1
      5 (19.66 cM)5
    760711  NM_178394.41  NP_848481.21 
     370283355 
    chicken
    (Gallus gallus)
    Aves JAKMIP11 janus kinase and microtubule interacting protein 1 76.73(n)
    84.96(a)
      422854  XM_004936175.1  XP_004936232.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    65(a)
    many ↔ many
    5(80450342-80496717)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX730452.12   -- 74.38(n)    BX730452.1 
    zebrafish
    (Danio rerio)
    Actinopterygii jakmip31 Janus kinase and microtubule interacting protein 3 67.33(n)
    68.44(a)
      555987  XM_678676.5  XP_683768.4 


    ENSEMBL Gene Tree for JAKMIP1 (if available)
    TreeFam Gene Tree for JAKMIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for JAKMIP1 gene
    JAKMIP32  JAKMIP22  
    2 SIMAP similar genes for JAKMIP1 using alignment to 3 protein entries:     JKIP1_HUMAN (see all proteins):
    JAKMIP3    JAKMIP2

    JAKMIP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for JAKMIP1 (see all 4397)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0394724
    A colorectal cancer sample4--see VAR_0394722 A V mis40--------
    rs1154362131,2
    C,F--6027436(+) CACAGG/TAGTCA 1 -- ds50011Minor allele frequency- T:0.05WA 118
    rs92911091,2
    C,F,H--6027465(+) GGGTGA/TGACGG 1 -- ds500113Minor allele frequency- T:0.11NA WA CSA 260
    rs731960651,2
    C--6027468(+) TGTGAC/TGGGGA 1 -- ds50010--------
    rs1422551971,2
    --6027485(+) TGAGTA/GGCTTC 1 -- ds50010--------
    rs1512834531,2
    C--6027580(+) CCCTCA/GGCCCT 1 -- ds50010--------
    rs1392947641,2
    --6027586(+) GCCCTA/GGAAGC 1 -- ds50010--------
    rs731960661,2
    C--6027646(+) GAGCAC/ACAGGG 1 -- ds50013Minor allele frequency- A:0.12NA WA 240
    rs1897917641,2
    --6027696(+) AGTCCC/TCCTTT 1 -- ds50010--------
    rs1818467181,2
    --6027744(+) TGAGCA/GTCCCT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for JAKMIP1 (6027926 - 6202318 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for JAKMIP1 (see all 27):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2726988CNV Deletion23290073
    esv2324557CNV Deletion18987734
    esv2726986CNV Deletion23290073
    esv2726985CNV Deletion23290073
    esv1003999CNV Deletion20482838
    esv998642CNV Deletion20482838
    esv2726990CNV Deletion23290073
    dgv919e199CNV Deletion23128226
    esv2675636CNV Deletion23128226
    esv2213984CNV Deletion18987734

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611195    OMIM disorders: --

    9 diseases for JAKMIP1:    
    About MalaCards
    crohn's disease    breast and colorectal cancer    tonsillitis    retinitis
    colorectal cancer    breast cancer    endotheliitis    prostatitis
    neuronitis


    JAKMIP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): JAKMIP1
    Human Genome Epidemiology (HuGE) Navigator: JAKMIP1 (2 documents)

    Export disorders for JAKMIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for JAKMIP1 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with JAKMIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Jamip1 (marlin-1) defines a family of proteins interacting with Janus kinases and microtubules. (PubMed id 15277531)1, 2, 9 Steindler C....Pellegrini S. (J. Biol. Chem. 2004)
    2. Identification and expression analysis of novel Jakmip1 transcripts. (PubMed id 17761393)1, 2, 9 Costa V....Ciccodicola A. (Gene 2007)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes. (PubMed id 18941173)1, 3 Libri V....Pellegrini S. (J. Immunol. 2008)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Marlin-1, a novel RNA-binding protein associates with GABA receptors. (PubMed id 14718537)1, 2 Couve A.... Moss S.J. (J. Biol. Chem. 2004)
    7. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    8. Overexpression of JAKMIP1 associates with Wnt/I^-catenin pathway activation and promotes cancer cell proliferation in vitro. (PubMed id 23481296)1 Okai I....Shao S. (amp 2013)
    9. Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. (PubMed id 22566498)1 Turner S.T....Boerwinkle E. (Hypertension 2012)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 152789 HGNC: 26460 AceView: MARLIN1 Ensembl:ENSG00000152969 euGenes: HUgn152789
    ECgene: JAKMIP1 H-InvDB: JAKMIP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for JAKMIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for JAKMIP1 gene:
    Search GeneIP for patents involving JAKMIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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