Aliases for JADE2 Gene
External Ids for JADE2 Gene
Previous HGNC Symbols for JADE2 Gene
Previous GeneCards Identifiers for JADE2 Gene
GeneCards Summary for JADE2 Gene
UniProtKB/Swiss-Prot for JADE2 Gene
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).