Aliases for IZUMO1R Gene
External Ids for IZUMO1R Gene
Previous HGNC Symbols for IZUMO1R Gene
GeneCards Summary for IZUMO1R Gene
UniProtKB/Swiss-Prot for IZUMO1R Gene
Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane fusogen. Does not bind folate (By similarity).