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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IWS1 Gene

protein-coding   GIFtS: 49
GCID: GC02M128193

IWS1 Homolog (S. Cerevisiae)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
IWS1 Homolog (S. Cerevisiae)1 2
IWS1-Like Protein2 3
Interacts With Spt62
Protein IWS1 Homolog2
IWS1L3

External Ids:    HGNC: 254671   Entrez Gene: 556772   Ensembl: ENSG000001631667   UniProtKB: Q96ST23   

Export aliases for IWS1 gene to outside databases

Previous GC identifers: GC02M127955 GC02M120545


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IWS1 Gene: 
IWS1 (IWS1 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with IWS1 include dentinogenesis imperfecta 1, and dentinogenesis imperfecta. GO annotations related to this gene include DNA binding.

Gene Wiki entry for IWS1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022135.16  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IWS1 gene promoter:
         E2F-4   E2F-3a   ER-alpha   E2F-5   p53   ATF-2   IRF-1   E2F-2   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIWS1 promoter sequence
   Search SABiosciences Chromatin IP Primers for IWS1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IWS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.3   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q14.3

IWS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IWS1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M128193:  view genomic region     (about GC identifiers)

Start:
128,193,783 bp from pter      End:
128,284,462 bp from pter
Size:
90,680 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IWS1_HUMAN, Q96ST2 (See protein sequence)
Recommended Name: Protein IWS1 homolog  
Size: 819 amino acids; 91955 Da
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=AAH65279.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=BAA91858.1; Type=Erroneous initiation;
Secondary accessions: Q2TB65 Q6P157 Q8N3E8 Q96MI7 Q9NV97 Q9NWH8
Alternative splicing: 3 isoforms:  Q96ST2-1   Q96ST2-2   Q96ST2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IWS1: NX_Q96ST2

Explore proteomics data for IWS1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96ST2

  • IWS1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IWS1 Protein Expression
    REFSEQ proteins: NP_060439.2  
    ENSEMBL proteins: 
     ENSP00000396710   ENSP00000295321   ENSP00000387206   ENSP00000399245  

    Human Recombinant Protein Products for IWS1: 
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    Cloud-Clone Corp. Proteins for IWS1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA17234882

    IWS1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for IWS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR017923 TFIIS_N

    Graphical View of Domain Structure for InterPro Entry Q96ST2

    ProtoNet protein and cluster: Q96ST2

    UniProtKB/Swiss-Prot: IWS1_HUMAN, Q96ST2
    Similarity: Belongs to the IWS1 family
    Similarity: Contains 1 TFIIS N-terminal domain


    IWS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI17234882
         
    IWS1 for ontologies           About GeneDecksing


    Animal Models:
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       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IWS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IWS1 
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    miRNA
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    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidIWS1 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of IWS1 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IWS1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for IWS1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Translational Control
    Translational Control

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for IWS1
        Translational Control



    IWS1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IWS1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/9 Interacting proteins for IWS1 (Q96ST23 ENSP000002953214) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SETD2Q9BYW23, ENSP000003867594I2D: score=1 STRING: ENSP00000386759
    SUPT6HQ7KZ853, ENSP000003191044I2D: score=1 STRING: ENSP00000319104
    WDR48Q8TAF33, ENSP000003074914I2D: score=2 STRING: ENSP00000307491
    POLR2AP249283, ENSP000003149494I2D: score=1 STRING: ENSP00000314949
    KBTBD7Q8WVZ93I2D: score=1 
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--
    GO:0010793regulation of mRNA export from nucleus IMP17234882

    IWS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IWS1

    Search CenterWatch for drugs/clinical trials and news about IWS1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IWS1 gene: 
    NM_017969.2  

    Unigene Cluster for IWS1:

    IWS1 homolog (S. cerevisiae)
    Hs.469879  [show with all ESTs]
    Unigene Representative Sequence: NM_017969
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000412979 ENST00000295321(uc010yzl.1 uc002ton.2 uc010fma.2)
    ENST00000497888 ENST00000495369 ENST00000409725 ENST00000486662 ENST00000479083
    ENST00000478949 ENST00000460511 ENST00000483889 ENST00000436740 ENST00000455721

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IWS1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate IWS1:
    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidIWS1 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IWS1
    Sirion Biotech Customized lentivirus for stable overexpression of IWS1 
                         Customized lentivirus expression plasmids for stable overexpression of IWS1 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IWS1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IWS1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IWS1

    Additional mRNA sequence: 

    AK000868.1 AK001717.1 AK027561.1 AK056881.1 AK294669.1 AK296848.1 AK309006.1 AL834178.1 
    BC017012.2 BC065279.1 BC110536.1 BC110537.1 

    18 DOTS entries:

    DT.445889  DT.100786048  DT.100786061  DT.120969741  DT.40113269  DT.91762095  DT.100786046  DT.120969723 
    DT.95108071  DT.100664924  DT.120969746  DT.40128203  DT.100786042  DT.120969720  DT.99991478  DT.86846841 
    DT.95108036  DT.120969751 

    24/263 AceView cDNA sequences (see all 263):

    AA936517 BC017012 AA287292 BQ217854 BM828974 AA598439 BM712471 AL834178 
    BX109403 BM467362 BM015640 BP363615 AI955524 BG656073 BP357296 BM832599 
    BC065279 BM979417 BP358935 BE464162 AA704787 AK000868 BM667591 CA867189 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for IWS1 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g · 7h · 7i ^ 8a · 8b ^ 9 ^
    SP1:                                                                                                                                                            
    SP2:              -     -     -     -     -     -                 -     -     -     -     -     -     -     -     -     -     -     -     -     -               
    SP3:              -     -     -     -     -     -                       -     -     -                                                                           
    SP4:                                                                    -     -     -                                                                           
    SP5:                                      -     -                       -     -     -                                                                           

    ExUns: 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for IWS1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IWS1 expression in normal human tissues (normalized intensities)      IWS1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IWS1 Expression
    About this image


    IWS1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/27 selected tissues (see all 27) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Breast
             breast ; myoepithelial cells   
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Islets of Langerhans
             pancreas ; exocrine glandular cells   

    See IWS1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IWS1

    SOURCE GeneReport for Unigene cluster: Hs.469879
        SABiosciences Custom PCR Arrays for IWS1
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IWS1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IWS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IWS1 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Iws11 , 5 IWS1 homolog (S. cerevisiae)1, 5 88.29(n)1
    90.83(a)1
      18 (17.92 cM)5
    734731  NM_173441.31  NP_775617.11 
     320677345 
    chicken
    (Gallus gallus)
    Aves IWS11 IWS1 homolog (S. cerevisiae) 72.88(n)
    71.51(a)
      424750  XM_422571.3  XP_422571.3 
    lizard
    (Anolis carolinensis)
    Reptilia IWS16
    IWS1 homolog (S. cerevisiae)
    68(a)
    1 ↔ 1
    3(36101806-36121039)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.123172 Xenopus laevis transcribed sequence with weak similarity more 73.71(n)    48016747 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.6902 Transcribed sequence with weak similarity to protein more 75.84(n)    57052041 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG99151 CG9915 37.79(n)
    29.96(a)
      32593  NM_001103530.1  NP_001097000.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F13B12.11 Protein F13B12.1 48.79(n)
    41.7(a)
      177934  NM_069523.3  NP_501924.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPN1(YPR133C)4
    SPN11
    Protein involved in RNA polymerase II transcription; more4
    Spn1p1
    43.08(n)1
    30.99(a)1
      16(797210-795978)4
    8562511, 4  NP_015458.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons IWS11 Transcription elongation factor (TFIIS) family protein 42.29(n)
    26.44(a)
      840105  NM_102946.3  NP_174492.2 
    rice
    (Oryza sativa)
    Liliopsida Os01g01472001 hypothetical protein 42.09(n)
    30.04(a)
      4325206  NM_001048546.1  NP_001042011.1 


    ENSEMBL Gene Tree for IWS1 (if available)
    TreeFam Gene Tree for IWS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1097 SNPs in IWS1 are shown (see all 1097)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1441394551,2
    C--128237897(+) GCAGAA/GCTTCT 1 -- ds50010--------
    rs116828641,2
    C,F,H--128237987(+) tgtggG/Agtcca 1 -- ds50015Minor allele frequency- A:0.21NA WA EA 246
    rs1473251571,2
    C--128238069(+) CTCCCA/GGGTCC 1 -- ds50010--------
    rs758733471,2
    C--128238084(+) GGCCCA/TACCCT 1 -- ds50010--------
    rs775711001,2
    C--128238085(+) GCCCAA/CCCCTC 1 -- ds50010--------
    rs562171221,2
    C,F--128238154(+) GTTAGC/TATAAC 1 -- ds50016Minor allele frequency- T:0.20WA CSA NA EA 363
    rs116945811,2
    C,F,A,H--128238166(+) AGAGAC/TGCTCT 1 -- ds500118Minor allele frequency- T:0.46NS EA NA WA 2342
    rs1390696441,2
    --128238209(+) TCCTTA/GTCAGC 1 -- ds50010--------
    rs756351051,2
    --128238212(+) TTGTCA/CGCAAC 1 -- ds50010--------
    rs1508558811,2
    --128238267(+) GAGGAC/TTGAAC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for IWS1 (128193783 - 128284462 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for IWS1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv875014CNV Loss21882294
    nsv2912CNV Loss18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for IWS1:    About MalaCards
    dentinogenesis imperfecta 1    dentinogenesis imperfecta


    IWS1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IWS1

    Export disorders for IWS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IWS1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with IWS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)1, 2 Beausoleil S.A....Gygi S.P. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. A bead-based approach for large-scale identification o f in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55677 HGNC: 25467 AceView: FLJ10006 Ensembl:ENSG00000163166 euGenes: HUgn55677
    ECgene: IWS1 H-InvDB: IWS1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IWS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IWS1 gene:
    Search GeneIP for patents involving IWS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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