Aliases for IVNS1ABP Gene
External Ids for IVNS1ABP Gene
Previous GeneCards Identifiers for IVNS1ABP Gene
GeneCards Summary for IVNS1ABP Gene
IVNS1ABP (Influenza Virus NS1A Binding Protein) is a Protein Coding gene. Diseases associated with IVNS1ABP include dengue hemorrhagic fever and influenza. Among its related pathways are Influenza A. An important paralog of this gene is GAN.
UniProtKB/Swiss-Prot for IVNS1ABP Gene
Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.