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Aliases for ITPRIPL2 Gene

Aliases for ITPRIPL2 Gene

  • Inositol 1,4,5-Trisphosphate Receptor Interacting Protein-Like 2 2 3
  • Inositol 1,4,5-Triphosphate Receptor Interacting Protein-Like 2 2

External Ids for ITPRIPL2 Gene

Previous GeneCards Identifiers for ITPRIPL2 Gene

  • GC16P019032
  • GC16P019125
  • GC16P017662

Summaries for ITPRIPL2 Gene

GeneCards Summary for ITPRIPL2 Gene

ITPRIPL2 (Inositol 1,4,5-Trisphosphate Receptor Interacting Protein-Like 2) is a Protein Coding gene. An important paralog of this gene is ITPRIP.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ITPRIPL2 Gene

Genomics for ITPRIPL2 Gene

Regulatory Elements for ITPRIPL2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ITPRIPL2 Gene

19,113,932 bp from pter
19,121,630 bp from pter
7,699 bases
Plus strand

Genomic View for ITPRIPL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ITPRIPL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ITPRIPL2 Gene

Proteins for ITPRIPL2 Gene

  • Protein details for ITPRIPL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ITPRIPL2 Gene

    535 amino acids
    Molecular mass:
    58446 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ITPRIPL2 Gene

Proteomics data for ITPRIPL2 Gene at MOPED

Post-translational modifications for ITPRIPL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ITPRIPL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ITPRIPL2 Gene

Domains for ITPRIPL2 Gene

Protein Domains for ITPRIPL2 Gene

Suggested Antigen Peptide Sequences for ITPRIPL2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ITPRIP family.
  • Belongs to the ITPRIP family.
genes like me logo Genes that share domains with ITPRIPL2: view

No data available for Gene Families for ITPRIPL2 Gene

Function for ITPRIPL2 Gene

Animal Model Products

CRISPR Products

miRNA for ITPRIPL2 Gene

miRTarBase miRNAs that target ITPRIPL2

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ITPRIPL2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for ITPRIPL2 Gene

Localization for ITPRIPL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ITPRIPL2 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for ITPRIPL2 Gene COMPARTMENTS Subcellular localization image for ITPRIPL2 gene
Compartment Confidence
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ITPRIPL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ITPRIPL2: view

Pathways for ITPRIPL2 Gene

SuperPathways for ITPRIPL2 Gene

No Data Available

Interacting Proteins for ITPRIPL2 Gene

Gene Ontology (GO) - Biological Process for ITPRIPL2 Gene


No data available for Pathways by source for ITPRIPL2 Gene

Transcripts for ITPRIPL2 Gene


(8) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ITPRIPL2 Gene

Inositol 1,4,5-trisphosphate receptor interacting protein-like 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ITPRIPL2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ITPRIPL2 Gene

No ASD Table

Relevant External Links for ITPRIPL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ITPRIPL2 Gene

mRNA expression in normal human tissues for ITPRIPL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ITPRIPL2 Gene

This gene is overexpressed in Placenta (59.8) and Urine (9.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ITPRIPL2 Gene

SOURCE GeneReport for Unigene cluster for ITPRIPL2 Gene Hs.530899

genes like me logo Genes that share expressions with ITPRIPL2: view

Expression partners for ITPRIPL2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ITPRIPL2 Gene

Orthologs for ITPRIPL2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ITPRIPL2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ITPRIPL2 35
  • 87.03 (n)
  • 89.1 (a)
  • 89 (a)
(Canis familiaris)
Mammalia ITPRIPL2 35
  • 86.65 (n)
  • 88.91 (a)
  • 88 (a)
(Mus musculus)
Mammalia Itpripl2 35
  • 83.55 (n)
  • 85.61 (a)
Itpripl2 16
Itpripl2 36
  • 84 (a)
(Pan troglodytes)
Mammalia ITPRIPL2 35
  • 99.81 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Itpripl2 35
  • 82.49 (n)
  • 85.05 (a)
(Monodelphis domestica)
Mammalia ITPRIPL2 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia ITPRIPL2 36
  • 70 (a)
(Gallus gallus)
Aves ITPRIPL2 35
  • 64.81 (n)
  • 55.9 (a)
(Anolis carolinensis)
Reptilia ITPRIPL2 36
  • 34 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia itpripl2 35
  • 51.87 (n)
  • 43.78 (a)
(Danio rerio)
Actinopterygii LOC555628 35
  • 51.88 (n)
  • 44.16 (a)
  • 40 (a)
Species with no ortholog for ITPRIPL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ITPRIPL2 Gene

Gene Tree for ITPRIPL2 (if available)
Gene Tree for ITPRIPL2 (if available)

Paralogs for ITPRIPL2 Gene

Paralogs for ITPRIPL2 Gene

genes like me logo Genes that share paralogs with ITPRIPL2: view

Variants for ITPRIPL2 Gene

Sequence variations from dbSNP and Humsavar for ITPRIPL2 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3210530 -- 19,116,726(-) GGAAG(C/T)TTCTC utr-variant-3-prime, nc-transcript-variant
rs3743955 -- 19,121,125(+) GATAA(A/C)GCATG utr-variant-3-prime, nc-transcript-variant
rs3743956 -- 19,121,458(+) ACAAT(C/T)GTATG utr-variant-3-prime, nc-transcript-variant
rs3760088 -- 19,118,689(+) GTGAA(G/T)TTTTA utr-variant-3-prime, nc-transcript-variant
rs3826249 -- 19,121,842(+) TGCTA(C/T)AGGTG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ITPRIPL2 Gene

Variant ID Type Subtype PubMed ID
esv587 CNV CNV 17122850
dgv823e1 CNV Complex 17122850
nsv436835 CNV Insertion 17901297

Relevant External Links for ITPRIPL2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ITPRIPL2 Gene

Disorders for ITPRIPL2 Gene

Relevant External Links for ITPRIPL2

Genetic Association Database (GAD)

No disorders were found for ITPRIPL2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ITPRIPL2 Gene

Publications for ITPRIPL2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen J.V. … Mann M. (Sci. Signal. 2010) 4

Products for ITPRIPL2 Gene

Sources for ITPRIPL2 Gene

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