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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ITPRIP Gene

protein-coding   GIFtS: 49
GCID: GC10M106062

Inositol 1,4,5-Trisphosphate Receptor Interacting Protein

(Previous names: KIAA1754, inositol 1,4,5-triphosphate receptor interacting...)
(Previous symbol: KIAA1754)
Alzheimer's & Parkinson's Diseases Congress
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at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Inositol 1,4,5-Trisphosphate Receptor Interacting Protein1 2     bA127L20.22
KIAA17541 2 3     Inositol 1,4,5-Triphosphate Receptor-Interacting Protein2
DANGER2 3     Inositol 1,4,5-Trisphosphate Receptor-Interacting Protein2
Inositol 1,4,5-Triphosphate Receptor Interacting Protein1     Protein DANGER3
bA127L202     

External Ids:    HGNC: 293701   Entrez Gene: 854502   Ensembl: ENSG000001488417   UniProtKB: Q8IWB13   

Export aliases for ITPRIP gene to outside databases

Previous GC identifer: GC10M099703


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ITPRIP Gene:
This gene encodes a membrane-associated protein that binds the inositol 1,4,5-trisphosphate receptor (ITPR). The
encoded protein enhances the sensitivity of ITPR to intracellular calcium signaling. Alternative splicing results
in multiple transcript variants. (provided by RefSeq, Dec 2012)

GeneCards Summary for ITPRIP Gene: 
ITPRIP (inositol 1,4,5-trisphosphate receptor interacting protein) is a protein-coding gene. Diseases associated with ITPRIP include west nile encephalitis, and specific phobia. An important paralog of this gene is ITPRIPL2.

UniProtKB/Swiss-Prot: IPRI_HUMAN, Q8IWB1
Function: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ITPRIP gene promoter:
         Meis-1b   POU2F1   POU2F1b   POU2F1a   FOXO4   FOXO1a   POU2F1c   NF-kappaB1   Meis-1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITPRIP promoter sequence
   Search SABiosciences Chromatin IP Primers for ITPRIP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITPRIP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.1   Ensembl cytogenetic band:  10q25.1   HGNC cytogenetic band: 10q25.1

ITPRIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITPRIP gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M106062:  view genomic region     (about GC identifiers)

Start:
106,071,894 bp from pter      End:
106,098,162 bp from pter
Size:
26,269 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IPRI_HUMAN, Q8IWB1 (See protein sequence)
Recommended Name: Inositol 1,4,5-trisphosphate receptor-interacting protein precursor  
Size: 547 amino acids; 62060 Da
Subunit: Interacts with ITPR
Subcellular location: Cell membrane
Sequence caution: Sequence=BAB21845.1; Type=Erroneous initiation;
Secondary accessions: D3DRA5 Q5JU17 Q96MS8 Q9C0A9

Explore the universe of human proteins at neXtProt for ITPRIP: NX_Q8IWB1

Explore proteomics data for ITPRIP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IWB1

  • ITPRIP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ITPRIP Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001258941.1  NP_001258942.1  NP_203755.1  

    ENSEMBL proteins: 
     ENSP00000337178   ENSP00000350915   ENSP00000414141   ENSP00000278071  

    Human Recombinant Protein Products for ITPRIP: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for ITPRIP
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ITPRIP
    GenScript Custom Purified and Recombinant Proteins Services for ITPRIP
    Novus Biologicals ITPRIP Protein
    Novus Biologicals ITPRIP Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ITPRIP 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--

    ITPRIP for ontologies           About GeneDecksing



    ITPRIP Antibody Products: 
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    Assay Products for ITPRIP: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for ITPRIP 
    Cloud-Clone Corp. CLIAs for ITPRIP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR024797 IP3R-int
     IPR026250 INOS145TPRIP
     IPR024810 Mab-21_dom
     IPR020950 Mab-21-rel

    Graphical View of Domain Structure for InterPro Entry Q8IWB1

    ProtoNet protein and cluster: Q8IWB1

    UniProtKB/Swiss-Prot: IPRI_HUMAN, Q8IWB1
    Similarity: Belongs to the ITPRIP family


    ITPRIP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IPRI_HUMAN, Q8IWB1
    Function: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004860protein kinase inhibitor activity IEA--
    GO:0005515protein binding ----
         
    ITPRIP for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ITPRIP:
     Decreased viability of wild-ty  High actin ratio cells 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Itprip):
     cellular  homeostasis/metabolism  nervous system  no phenotypic analysis 

    ITPRIP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Itpriptm1.1Snyd for ITPRIP

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ITPRIP 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ITPRIP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ITPRIP 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ITPRIP 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ITPRIP
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate ITPRIP (see all 19):
    hsa-miR-3910 hsa-miR-485-5p hsa-miR-4254 hsa-miR-639 hsa-miR-1205 hsa-miR-1297 hsa-miR-515-5p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidITPRIP 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ITPRIP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITPRIP

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of ITPRIP

    Clone
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    OriGene clones in human, mouse for ITPRIP (see all 7)
    OriGene ORF clones in mouse, rat for ITPRIP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITPRIP (NM_033397)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITPRIP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITPRIP
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                         Customized lentivirus expression plasmids for stable overexpression of ITPRIP 

    Cell Line
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    Search LifeMap BioReagents cell lines for ITPRIP
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITPRIP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ITPRIP

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ITPRIP (ENSP000002780714) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITPR1ENSP000004059344STRING: ENSP00000405934
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006469negative regulation of protein kinase activity ----
    GO:0043066negative regulation of apoptotic process IEA--

    ITPRIP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ITPRIP (IPRI)

    Search CenterWatch for drugs/clinical trials and news about ITPRIP / IPRI

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ITPRIP gene (3 alternative transcripts): 
    NM_001272012.1  NM_001272013.1  NM_033397.3  

    Unigene Cluster for ITPRIP:

    Inositol 1,4,5-trisphosphate receptor interacting protein
    Hs.523252  [show with all ESTs]
    Unigene Representative Sequence: NM_033397
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000337478(uc001kyg.3) ENST00000358187(uc001kye.3) ENST00000458723
    ENST00000278071(uc001kyf.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ITPRIP
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate ITPRIP (see all 19):
    hsa-miR-3910 hsa-miR-485-5p hsa-miR-4254 hsa-miR-639 hsa-miR-1205 hsa-miR-1297 hsa-miR-515-5p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidITPRIP 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ITPRIP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITPRIP
    Clone
    Products:
         
    OriGene clones in human, mouse for ITPRIP (see all 7)
    OriGene ORF clones in mouse, rat for ITPRIP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITPRIP (NM_033397)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITPRIP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITPRIP
    Sirion Biotech Customized lentivirus for stable overexpression of ITPRIP 
                         Customized lentivirus expression plasmids for stable overexpression of ITPRIP 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ITPRIP
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ITPRIP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITPRIP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITPRIP

    Additional mRNA sequence: 

    AB051541.1 AK055608.1 AK056526.1 AK094802.1 AK129877.1 AY189283.1 AY358776.1 BC040536.1 
    BC070108.1 

    6 DOTS entries:

    DT.100771557  DT.100771556  DT.413738  DT.435096  DT.100771559  DT.99968479 

    24/122 AceView cDNA sequences (see all 122):

    BC070108 AB051541 BM693107 AA682661 CA446184 BC040536 CD365193 AW296133 
    CO245386 AA479528 AI910786 BI062548 BF000686 CD517856 BI053557 BU677876 
    BM710925 BF885441 BM695216 NM_033397 BQ002177 CO246643 CA391089 AA631174 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ITPRIP    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
    SP1:                    -                     
    SP2:                                          
    SP3:        -     -     -                     


    ECgene alternative splicing isoforms for ITPRIP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ITPRIP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCCTTATT
    ITPRIP Expression
    About this image


    See ITPRIP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ITPRIP

    SOURCE GeneReport for Unigene cluster: Hs.523252

    UniProtKB/Swiss-Prot: IPRI_HUMAN, Q8IWB1
    Tissue specificity: Detected in brain where it is concentrated in cerebellar Purkinje cells (at protein level)

        SABiosciences Custom PCR Arrays for ITPRIP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITPRIP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ITPRIP gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Itprip1 , 5 inositol 1,4,5-triphosphate receptor interacting protein1, 5 81.68(n)1
    78.68(a)1
      19 (40.49 cM)5
    4148011  NM_001001738.21  NP_001001738.21 
     478945985 
    chicken
    (Gallus gallus)
    Aves ITPRIP1 inositol 1,4,5-trisphosphate receptor interacting protein 65.56(n)
    59.81(a)
      428979  XM_426536.3  XP_426536.3 
    lizard
    (Anolis carolinensis)
    Reptilia ITPRIP6
    Uncharacterized protein
    55(a)
    1 ↔ 1
    3(41619064-41620713)
    zebrafish
    (Danio rerio)
    Actinopterygii itprip1 inositol 1,4,5-triphosphate receptor interacting protein 54.35(n)
    48.44(a)
      550570  NM_001017872.1  NP_001017872.1 


    ENSEMBL Gene Tree for ITPRIP (if available)
    TreeFam Gene Tree for ITPRIP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ITPRIP gene
    ITPRIPL22  ITPRIPL12  
    1 SIMAP similar gene for ITPRIP using alignment to 1 protein entry:     IPRI_HUMAN:
    ITPRIPL1

    ITPRIP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/571 SNPs in ITPRIP are shown (see all 571)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs765138251,2
    C--106431372(+) CAGACA/GGTGAG 3 -- ds50010--------
    rs575342331,2
    C--106431409(+) TATAT-/A/ATA 
    TATA
    /TTT
    TATAT
    6 -- ds5001 cds11NA 2
    rs2018530391,2
    C--106431409(+) TATAT-/AT    
       ATATA
    TTTTT
    3 -- ds50010--------
    rs1999143021,2
    --106431413(+) TATAT-/ATATTTTT 3 -- ds50010--------
    rs74779191,2
    A--106431415(+) tatatA/Tttttt 3 -- ds50011Minor allele frequency- T:0.00NA 2
    rs611481811,2
    C--106431415(+) TATAT-/ATTTTT 3 -- ds50010--------
    rs79042021,2
    C,A--106431417(+) tatatA/Tttttt 3 -- ds50010--------
    rs1500615871,2
    C--106431544(+) CCTCCG/TGAGTA 3 -- ds50010--------
    rs1874655201,2
    --106431701(+) GGTGTA/GAGCTA 3 -- ds50010--------
    rs1928491781,2
    --106431859(+) ACACAG/TAAAAA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for ITPRIP (106071894 - 106098162 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ITPRIP:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1968684CNV Deletion18987734

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ITPRIP
    DNA2.0 Custom Variant and Variant Library Synthesis for ITPRIP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for ITPRIP:    About MalaCards
    west nile encephalitis    specific phobia    encephalitis    alzheimer's disease


    ITPRIP for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): ITPRIP
    Human Genome Epidemiology (HuGE) Navigator: ITPRIP (2 documents)

    Export disorders for ITPRIP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ITPRIP gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ITPRIP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate- receptor activity. (PubMed id 16990268)1, 2, 3 van Rossum D.B.... Snyder S.H. (2006)
    2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. PHYRN: a robust method for phylogenetic analysis of hi ghly divergent sequences. (PubMed id 22514627)1 Bhardwaj G....van Rossum D.B. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    9. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    10. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 85450 HGNC: 29370 AceView: KIAA1754 Ensembl:ENSG00000148841 euGenes: HUgn85450
    ECgene: ITPRIP H-InvDB: ITPRIP

    (According to HUGE)
    About This Section
    HUGE: KIAA1754

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ITPRIP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ITPRIP gene:
    Search GeneIP for patents involving ITPRIP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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