ITPKC Gene
protein-coding GIFtS: 61
GCID: GC19P041223
|
|
inositol-trisphosphate 3-kinase C(Previous name: inositol 1,4,5-trisphosphate 3-kinase C )
| |
Aliases
for ITPKC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Inositol-Trisphosphate 3-Kinase C1 2 | | IP3 3-Kinase C2 3 | | Inositol 1,4,5-Trisphosphate 3-Kinase C1 2 3 | | IP3K C2 3 | | IP3KC1 2 3 | | EC 2.7.1.1273 8 | | IP3-3KC1 2 | | InsP 3 Kinase C2 | | InsP 3-Kinase C2 3 | | |
Export aliases for ITPKC gene to outside databasesPrevious GC identifers: GC19P041862 GC19P041614 GC19P045899 GC19P045914 GC19P037656 |
Summaries
for ITPKC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ITPKC:
This gene encodes a member of the inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)) 3-kinase family of enzymes thatcatalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein islocalized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotidepolymorphisms in this gene are associated with Kawasaki disease.(provided by RefSeq, Sep 2009)
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7Function: Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity)
|
Genomic Views
for ITPKC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ITPKC gene promoter:
SRF COUP-TF1 NF-1 Lmo2 COUP HNF-4alpha2 HNF-4alpha1 COUP-TF c-Myb
Other transcription factors
Search SABiosciences Chromatin IP Primers for ITPKC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITPKC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.1ITPKC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P041223: view genomic region
(about GC identifiers)
Start:
|
41,223,008 bp from pter |
End:
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41,246,765 bp from pter |
Size:
|
23,758 bases |
Orientation:
|
plus strand |
|
Proteins
for ITPKC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7 (See
protein sequence)Recommended Name: Inositol-trisphosphate 3-kinase C Size: 683 amino acids; 75207 Da
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear importand nuclear export activity
1 PDB 3D structure from  and Proteopedia  for ITPKC:2A98 (3D)
Secondary accessions: Q9UE25 Q9Y475Explore the universe of human proteins at neXtProt for ITPKC: NX_Q96DU7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96DU7
3 DME Specific Peptides for ITPKC (Q96DU7)
ITPKC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079470.1
ENSEMBL proteins: ENSP00000263370 Reactome Protein details: Q96DU7
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ITPKC for ontologies About GeneDecksing
ITPKC Antibody Products:
Assay Products for ITPKC: |
Protein
Domains /
Families
for ITPKC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ITPKC for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96DU7ProtoNet protein and cluster: Q96DU7 1 Blocks protein family: IPB005522 Inositol polyphosphate kinase
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7Similarity: Belongs to the inositol phosphokinase (IPK) family |
Function
for ITPKC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7Function: Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity)Catalytic activity: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphateEnzyme regulation: Activated by calcium/calmodulin. Inhibited by high concentrations of the substrate Ins(1,2,4)P3, andallosterically activated by the product Ins(1,3,4,5)P4 Genatlas biochemistry entry for ITPKC:inositol,1,4,5-triphosphate 3 kinase-C
Enzyme Number (IUBMB): EC 2.7.1.1271 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ITPKC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITPKC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITPKC |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ITPKC for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ITPKC:
Animal Models:
Mouse knock-out Itpkctm1Ssch for ITPKC
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Itpkc):
ITPKC for phenotypes About GeneDecksing
|
Pathways & Interactions
for ITPKC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | | | 2 | Synthesis of IP3 and IP4 in the cytosol | | | 3 | Metabolism | | | 4 | Integrated Breast Cancer Pathway | | | 5 | Inositol phosphate metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5  BioSystems Pathways for ITPKC
3 
Reactome Pathways for ITPKC
ITPKC for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ITPKC
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/26 Interacting proteins for ITPKC (Q96DU73 ENSP000002633704) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016310 | phosphorylation |
-- | -- |
ITPKC for ontologies About GeneDecksing
|
Drugs & Compounds
for ITPKC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ITPKC
1 HMDB Compound for ITPKC About this table
Search CenterWatch for drugs/clinical trials and news about ITPKC / IP3KC
|
Transcripts
for ITPKC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ITPKC gene: NM_025194.2 Unigene Cluster for ITPKC: Inositol-trisphosphate 3-kinase C Hs.515415 [show with all ESTs]Unigene Representative Sequence: BC0607881 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000263370(uc002oot.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ITPKC (NM_025194) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ITPKC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITPKC |
Additional cDNA sequence: AJ290975.1 AK024596.1 BC026903.1 BC060788.1 D38169.1 Y11999.1 8 DOTS entries: DT.113294 DT.101981800 DT.100027507 DT.91741016 DT.102842819 DT.91708655 DT.91859410 DT.91929800 24/147 AceView cDNA sequences (see all 147): BM672379 BU684480 CD632520 BQ685920 BQ956895 NM_025194 BM975488 CA440554 BM126474 BM068742 AI276629 AI906000 CA454772 BU684434 BF342350 Y11999 CO395285 BQ647009 CD632522 AJ290975 BU174652 BX477633 BC026903 BM702344
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for ITPKC About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ITPKC
|
Expression
for ITPKC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ITPKC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAACACCCC
About this image
See ITPKC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ITPKC
SOURCE GeneReport for Unigene cluster: Hs.515415
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7Tissue specificity: Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain
SABiosciences Custom PCR Arrays for ITPKC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ITPKC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ITPKC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITPKC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITPKC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITPKC |
Orthologs
for ITPKC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ITPKC gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Itpkc1 , 5 |
inositol 1,4,5-trisphosphate 3-kinase C1, 5 |
81.65(n)1
77.08(a)1 |
|
7 (15.85 cM)5
2330111 NM_181593.21 NP_853624.11
272071725 |
lizard
(Anolis carolinensis) |
Reptilia |
ITPKC6 |
-- |
69(a) |
1 ↔ 1 |
LGf(2766974-2774244) |
zebrafish
(Danio rerio) |
Actinopterygii |
itpkca1 |
inositol 1,4,5-trisphosphate 3-kinase Ca |
64.24(n)
62.01(a) |
|
562919 XM_681366.5 XP_686458.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
IP3K23 |
1D-myo-inositol-trisphosphate 3-kinase |
53(a)
(best of 2) |
|
11E11 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
lfe-23 |
Expression: alimentary system, intestine,
pharynx, more |
44(a) |
|
I(5027212-5040766) -- |
ENSEMBL Gene Tree for ITPKC (if available)
TreeFam Gene Tree for ITPKC (if available) |
Paralogs
for ITPKC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ITPKC gene
- ITPKB2 ITPKA2
3 SIMAP similar genes for ITPKC using alignment to 2 protein entries: IP3KC_HUMAN (see all proteins):ITPKA PIG37 ITPKB
ITPKC for paralogs About GeneDecksing
|
Genomic Variants
for ITPKC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ITPKC (41223008 - 41246765 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ITPKC: --
Human Gene Mutation Database (HGMD): ITPKC
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITPKC |
|
Disorders
/ Diseases
for ITPKC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ITPKC for disorders About GeneDecksing
OMIM gene information: 606476
OMIM disorders: 611775
UniProtKB/Swiss-Prot: IP3KC_HUMAN, Q96DU7
Defects in ITPKC are a cause of Kawasaki disease (KWD) [MIM:611775]; also known as mucocutaneous lymph nodesyndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and childrencharacterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa,lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy.Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause ofacquired heart disease among children in developed countries
4  diseases for ITPKC: About MalaCardskawasaki disease cutis laxa coronary artery aneurysm hermaphroditism
2 diseases from the University of Copenhagen DISEASES database for ITPKC:Kawasaki disease Vasculitis Human Genome Epidemiology (HuGE) Navigator: ITPKC (3 documents)
Export disorders for ITPKC gene to outside databases
|
Publications
for ITPKC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ITPKC gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ITPKC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and expression of a cDNA encoding human inositol 1,4,5- trisphosphate 3-kinase C. (PubMed id 11085927)1, 2, 3, 9 Dewaste V.... Erneux C. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells. (PubMed id 12747803)1, 2 Dewaste V.... Erneux C. (2003)
- ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. (PubMed id 18084290)1, 9 Onouchi Y....Hata A. (2008)
- Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains. (PubMed id 16740130)1, 9 Nalaskowski M.M....Mayr G.W. (2006)
- ITPKC susceptibility in Kawasaki syndrome as a sensiti zing factor for autoimmunity and coronary arterial wall relaxation induced by th imerosal's effects on calcium signaling via IP3. (PubMed id 22498790)1 Yeter D. and Deth R. (2012)
- Single-nucleotide polymorphism rs2290692 in the 3'UTR of ITPKC associated with susceptibility to Kawasaki disease in a Han Chinese pop ulation. (PubMed id 22361738)1 Peng Q....Yang Y. (2012)
- Genetic polymorphisms in the ITPKC gene and cervical s quamous cell carcinoma risk. (PubMed id 22610085)1 Yang Y.C....Lee Y.J. (2012)
- ITPKC single nucleotide polymorphism associated with the Kawasaki disease in a Taiwanese population. (PubMed id 21533171)1 Kuo H.C....Chang W.C. (2011)
- Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. (PubMed id 22081228)1 Khor C.C.... . (2011)
|
External Searches for ITPKC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ITPKC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ITPKC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ITPKC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ITPKC | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ITPKC gene:
Search GeneIP for patents involving ITPKC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ITPKC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ITPKC | | OriGene shRNA RFP for ITPKC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ITPKC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ITPKC | | | OriGene Protein Over-expression Lysate for ITPKC | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ITPKC | | OriGene 3'-UTR Clone for ITPKC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITPKC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ITPKC | | OriGene Custom Protein Services for ITPKC | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ITPKC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITPKC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITPKC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITPKC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITPKC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITPKC |
| |
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| | | | Search Tocris compounds for ITPKC |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ITPKC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITPKC |
|  |  |  | | | | ThermoFisher Antibody for ITPKC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITPKC |
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