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Aliases for ITPK1 Gene

Aliases for ITPK1 Gene

  • Inositol-Tetrakisphosphate 1-Kinase 2 3 5
  • Inositol 1,3,4-Trisphosphate 5/6-Kinase 3 4
  • Ins(1,3,4)P(3) 5/6-Kinase 3 4
  • Inositol 1,3,4-Triphosphate 5/6 Kinase 2
  • Inositol-Triphosphate 5/6-Kinase 4
  • EC 2.7.1.134 4
  • EC 2.7.1.159 4
  • ITRPK1 3

External Ids for ITPK1 Gene

Previous GeneCards Identifiers for ITPK1 Gene

  • GC14M090910
  • GC14M087219
  • GC14M091393
  • GC14M091394
  • GC14M092473
  • GC14M093403
  • GC14M073584

Summaries for ITPK1 Gene

Entrez Gene Summary for ITPK1 Gene

  • This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]

GeneCards Summary for ITPK1 Gene

ITPK1 (Inositol-Tetrakisphosphate 1-Kinase) is a Protein Coding gene. Diseases associated with ITPK1 include Neural Tube Defects. Among its related pathways are Inositol phosphate metabolism (KEGG) and Metabolism. GO annotations related to this gene include magnesium ion binding and inositol tetrakisphosphate 1-kinase activity.

UniProtKB/Swiss-Prot for ITPK1 Gene

  • Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Gene Wiki entry for ITPK1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ITPK1 Gene

Genomics for ITPK1 Gene

Regulatory Elements for ITPK1 Gene

Enhancers for ITPK1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F093112 0.6 ENCODE 29.2 +1.4 1378 5.1 SIN3A ZNF48 ZNF2 ZNF121 GLIS2 ZNF143 ZNF207 FOS SP3 REST ITPK1 MOAP1 TMEM251 GC14P093068 ITPK1-AS1
GH14F093089 0.7 Ensembl ENCODE 28.5 +24.7 24720 5.2 ITPK1 GC14P093068 ITPK1-AS1
GH14F093098 1.2 FANTOM5 Ensembl ENCODE 27.5 +12.5 12546 10.5 CTCF KLF1 IRF2 PKNOX1 CEBPG EBF1 RAD21 ZNF121 ZFHX2 POLR2A ITPK1 TMEM251 ITPK1-AS1 MOAP1 UNC79 GC14P093068
GH14F093120 1.3 FANTOM5 Ensembl 27.2 -4.7 -4703 0.4 STAT1 ESRRA TBX21 RARA GATA2 IKZF1 STAT2 BCL6 SPI1 ITPK1 UNC79 GC14P093119 CYB5AP3
GH14F093096 0.2 Ensembl 26.1 +19.4 19420 1.8 ZNF146 ZNF580 ITPK1 ITPK1-AS1 CHGA GC14P093068
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ITPK1 on UCSC Golden Path with GeneCards custom track

Promoters for ITPK1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000422839 1020 2601 SIN3A ZNF48 RAD21 ZBTB40 GLIS2 EGR1 ZNF207 SP3 ZEB2 REST

Genomic Location for ITPK1 Gene

Chromosome:
14
Start:
92,936,914 bp from pter
End:
93,116,320 bp from pter
Size:
179,407 bases
Orientation:
Minus strand

Genomic View for ITPK1 Gene

Genes around ITPK1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ITPK1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ITPK1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ITPK1 Gene

Proteins for ITPK1 Gene

  • Protein details for ITPK1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13572-ITPK1_HUMAN
    Recommended name:
    Inositol-tetrakisphosphate 1-kinase
    Protein Accession:
    Q13572
    Secondary Accessions:
    • Q9BTL6
    • Q9H2E7

    Protein attributes for ITPK1 Gene

    Size:
    414 amino acids
    Molecular mass:
    45621 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Monomer. Interacts with GPS1/COPS1.

    Three dimensional structures from OCA and Proteopedia for ITPK1 Gene

    Alternative splice isoforms for ITPK1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ITPK1 Gene

Post-translational modifications for ITPK1 Gene

  • Acetylation by EP300 and CREBBP destabilizes ITPK1, and down-regulates enzymatic activity. Deacetylated by SIRT1.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ITPK1 Gene

Domains & Families for ITPK1 Gene

Protein Domains for ITPK1 Gene

Suggested Antigen Peptide Sequences for ITPK1 Gene

Graphical View of Domain Structure for InterPro Entry

Q13572

UniProtKB/Swiss-Prot:

ITPK1_HUMAN :
  • Contains 1 ATP-grasp domain.
  • Belongs to the ITPK1 family.
Domain:
  • Contains 1 ATP-grasp domain.
Family:
  • Belongs to the ITPK1 family.
genes like me logo Genes that share domains with ITPK1: view

No data available for Gene Families for ITPK1 Gene

Function for ITPK1 Gene

Molecular function for ITPK1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.3 uM for Ins(1,3,4)P3 {ECO:0000269 PubMed:11042108}; KM=0.1 uM for Ins(3,4,5,6)P4 {ECO:0000269 PubMed:11042108}; Vmax=320 pmol/min/ug enzyme with Ins(1,3,4)P3 as substrate {ECO:0000269 PubMed:11042108}; Vmax=780 pmol/min/ug enzyme enzyme with Ins(3,4,5,6)P4 as substrate {ECO:0000269 PubMed:11042108};
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate.
UniProtKB/Swiss-Prot Function:
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Enzyme Numbers (IUBMB) for ITPK1 Gene

Gene Ontology (GO) - Molecular Function for ITPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000287 magnesium ion binding IEA --
GO:0003824 catalytic activity TAS 8662638
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with ITPK1: view
genes like me logo Genes that share phenotypes with ITPK1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for ITPK1

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for ITPK1

Flow Cytometry Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ITPK1 Gene

Localization for ITPK1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ITPK1 Gene COMPARTMENTS Subcellular localization image for ITPK1 gene
Compartment Confidence
cytosol 5
mitochondrion 3
nucleus 2

Gene Ontology (GO) - Cellular Components for ITPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005829 cytosol TAS --
GO:0016324 apical plasma membrane IEA --
genes like me logo Genes that share ontologies with ITPK1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ITPK1 Gene

Pathways & Interactions for ITPK1 Gene

genes like me logo Genes that share pathways with ITPK1: view

Gene Ontology (GO) - Biological Process for ITPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction TAS 8662638
GO:0007596 blood coagulation TAS --
GO:0016310 phosphorylation IEA --
GO:0016311 dephosphorylation IEA --
GO:0021915 neural tube development IEA --
genes like me logo Genes that share ontologies with ITPK1: view

No data available for SIGNOR curated interactions for ITPK1 Gene

Drugs & Compounds for ITPK1 Gene

(2) Drugs for ITPK1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Adenosine triphosphate Approved Nutra 0
Magnesium Nutra 0

(7) Additional Compounds for ITPK1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
1D-Myo-inositol 1,3,4,6-tetrakisphosphate
  • 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
  • D-Myo-inositol 1,3,4,5-tetrakis-*phosphate potass
  • D-Myo-inositol 1,3,4,6-tetrakisphosphate
  • D-Myo-Inositol-1,3,4,5-tetrakisphosphate octapotassium salt
  • Inositol 1,3,4,6-tetrakisphosphate
110298-84-5
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
D-Myo-inositol 3,4,5,6-tetrakisphosphate
  • 1D-Myo-Inositol 3,4,5,6-tetrakisphosphate
  • D-Myo-Inositol, 3,4,5,6-tetrakis(dihydrogen phosphate)
  • Inositol 3,4,5,6-tetrakisphosphate
112791-61-4
Inositol 1,3,4,5,6-pentakisphosphate
  • 1D-Myo-Inositol 1,3,4,5,6-pentakisphosphate
  • Inositol 1,3,4,5,6-pentaphosphate
  • Inositol pentaphosphate
  • Myo-Inositol 1,3,4,5,6-pentakis(phosphate)
  • Myo-Inositol 1,3,4,5,6-pentaphosphate
20298-95-7
Inositol 1,3,4,5-tetraphosphate
  • 1,3,4,5-Tetrakis(dihydrogen phosphate) myo-Inositol
  • 1D-Myo-inositol 1,3,4,5-tetrakis(dihydrogen phosphate)
  • 1D-Myo-inositol 1,3,4,5-tetrakisphosphate
  • D-Myo-inositol 1,3,4,5-tetrakisphosphate
  • Inositol 1,3,4,5-tetrakis(phosphate)
102850-29-3
genes like me logo Genes that share compounds with ITPK1: view

Transcripts for ITPK1 Gene

Unigene Clusters for ITPK1 Gene

Inositol-tetrakisphosphate 1-kinase:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for ITPK1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ITPK1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2:

Relevant External Links for ITPK1 Gene

GeneLoc Exon Structure for
ITPK1
ECgene alternative splicing isoforms for
ITPK1

Expression for ITPK1 Gene

mRNA expression in normal human tissues for ITPK1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ITPK1 Gene

This gene is overexpressed in Monocytes (9.0) and Spinal cord (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ITPK1 Gene



Protein tissue co-expression partners for ITPK1 Gene

NURSA nuclear receptor signaling pathways regulating expression of ITPK1 Gene:

ITPK1

SOURCE GeneReport for Unigene cluster for ITPK1 Gene:

Hs.308122

mRNA Expression by UniProt/SwissProt for ITPK1 Gene:

Q13572-ITPK1_HUMAN
Tissue specificity: Expressed in brain > heart > skeletal muscle = kidney = pancreas = liver = placenta > lung. In brain, it is expressed in cerebellum, cerebral cortex, medulla, spinal cord, occipital lobe, frontal lobe, temporal lobe and putamen.
genes like me logo Genes that share expression patterns with ITPK1: view

Primer Products

No data available for mRNA differential expression in normal tissues for ITPK1 Gene

Orthologs for ITPK1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ITPK1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ITPK1 34 35
  • 96.46 (n)
cow
(Bos Taurus)
Mammalia ITPK1 34 35
  • 91.71 (n)
dog
(Canis familiaris)
Mammalia ITPK1 34 35
  • 90.58 (n)
rat
(Rattus norvegicus)
Mammalia Itpk1 34
  • 89.05 (n)
mouse
(Mus musculus)
Mammalia Itpk1 34 16 35
  • 88.24 (n)
oppossum
(Monodelphis domestica)
Mammalia ITPK1 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ITPK1 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves ITPK1 34 35
  • 77.64 (n)
lizard
(Anolis carolinensis)
Reptilia ITPK1 35
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia itpk1 34
  • 74.06 (n)
zebrafish
(Danio rerio)
Actinopterygii ITPK1 (2 of 2) 35
  • 72 (a)
OneToMany
LOC100148744 34
  • 71.86 (n)
itpk1 35
  • 64 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G33770 34
  • 42.82 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1337 35
  • 41 (a)
OneToOne
Species where no ortholog for ITPK1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ITPK1 Gene

ENSEMBL:
Gene Tree for ITPK1 (if available)
TreeFam:
Gene Tree for ITPK1 (if available)

Paralogs for ITPK1 Gene

Pseudogenes.org Pseudogenes for ITPK1 Gene

genes like me logo Genes that share paralogs with ITPK1: view

No data available for Paralogs for ITPK1 Gene

Variants for ITPK1 Gene

Sequence variations from dbSNP and Humsavar for ITPK1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs757209932 Uncertain significance 92,946,358(+) GACGG(C/T)GTGCT reference, missense
rs1006888 -- 92,952,607(+) CAATT(C/T)CTCTT intron-variant
rs10132322 -- 93,021,598(+) AAAAA(A/G)AAAAA intron-variant
rs10132511 -- 93,098,802(+) CTTCC(C/G)GAGCT intron-variant
rs10135073 -- 93,052,200(+) aaggt(A/G)ggata intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ITPK1 Gene

Variant ID Type Subtype PubMed ID
dgv3841n54 CNV loss 21841781
dgv3842n54 CNV loss 21841781
dgv3843n54 CNV gain+loss 21841781
dgv3844n54 CNV gain+loss 21841781
dgv3845n54 CNV gain 21841781
dgv3846n54 CNV loss 21841781
dgv3847n54 CNV gain+loss 21841781
dgv3848n54 CNV gain 21841781
dgv3849n54 CNV gain+loss 21841781
dgv3850n54 CNV gain 21841781
dgv3851n54 CNV loss 21841781
dgv3852n54 CNV loss 21841781
esv2674911 CNV deletion 23128226
esv26978 CNV loss 19812545
esv29164 CNV gain 19812545
esv3635349 CNV loss 21293372
esv3635350 CNV gain 21293372
esv3892576 CNV loss 25118596
nsv1040456 CNV gain 25217958
nsv1069815 CNV deletion 25765185
nsv1121877 CNV deletion 24896259
nsv1126372 CNV deletion 24896259
nsv1400 CNV deletion 18451855
nsv1401 CNV deletion 18451855
nsv1402 CNV insertion 18451855
nsv456401 CNV loss 19166990
nsv456402 CNV loss 19166990
nsv470656 CNV loss 18288195
nsv470657 CNV gain 18288195
nsv517691 CNV loss 19592680
nsv565526 CNV loss 21841781
nsv565529 CNV gain 21841781
nsv565535 CNV loss 21841781
nsv565546 CNV loss 21841781
nsv565550 CNV gain 21841781
nsv565558 CNV gain 21841781
nsv827028 CNV gain 20364138
nsv85386 CNV deletion 16902084
nsv952884 CNV deletion 24416366

Variation tolerance for ITPK1 Gene

Residual Variation Intolerance Score: 19.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ITPK1 Gene

Human Gene Mutation Database (HGMD)
ITPK1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ITPK1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ITPK1 Gene

Disorders for ITPK1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ITPK1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
neural tube defects
  • spina bifida
- elite association - COSMIC cancer census association via MalaCards
Search ITPK1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for ITPK1

Genetic Association Database (GAD)
ITPK1
Human Genome Epidemiology (HuGE) Navigator
ITPK1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ITPK1
genes like me logo Genes that share disorders with ITPK1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ITPK1 Gene

Publications for ITPK1 Gene

  1. Integration of inositol phosphate signaling pathways via human ITPK1. (PMID: 17616525) Chamberlain P.P. … Spraggon G. (J. Biol. Chem. 2007) 3 4 22 64
  2. Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P(4) 1-kinase/Ins(1,3,4)P(3) 5/6-kinase. (PMID: 11042108) Yang X. … Shears S.B. (Biochem. J. 2000) 2 3 4 64
  3. Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme. (PMID: 8662638) Wilson M.P. … Majerus P.W. (J. Biol. Chem. 1996) 2 3 4 64
  4. Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation. (PMID: 22308441) Zhang C. … Wilson M.P. (Proc. Natl. Acad. Sci. U.S.A. 2012) 3 4 64
  5. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 3 46 64

Products for ITPK1 Gene

Sources for ITPK1 Gene

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