ITM2C Gene
protein-coding GIFtS: 51
GCID: GC02P231693
|
|
integral membrane protein 2C
| |
Aliases for ITM2C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Integral Membrane Protein 2C1 2 | | Cerebral Protein 142 3 | | BRI31 2 3 5 | | Transmembrane Protein BRI32 3 | | BRICD2C1 2 | | E25C2 | | E251 2 | | BRICHOS Domain Containing 2C2 | | ITM31 2 | | Integral Membrane Protein 32 | | HRPC.1050_D_41 | | |
Export aliases for ITM2C gene to outside databasesPrevious GC identifers: GC02U990099 GC02P230461 GC02P231932 GC02P231555 GC02P231437 GC02P223571 |
Summaries for ITM2C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ITM2C_HUMAN, Q9NQX7Function: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking itsaccess to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible,suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death andneuronal differentiation (By similarity) Gene Wiki entry for ITM2C
|
Genomic Views for ITM2C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ITM2C gene promoter: Spz1 Sp1 AP-1 SREBP-1c MyoD Tal-1beta SREBP-1b Arnt SREBP-1a ITF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for ITM2C
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITM2C |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37 Ensembl cytogenetic band: 2q37.1 HGNC cytogenetic band: 2q37ITM2C Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P231693: view genomic region
(about GC identifiers)
Start:
|
231,729,354 bp from pter |
End:
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231,743,963 bp from pter |
Size:
|
14,610 bases |
Orientation:
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plus strand |
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Proteins for ITM2C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ITM2C_HUMAN, Q9NQX7 (See
protein sequence)Recommended Name: Integral membrane protein 2C Size: 267 amino acids; 30224 Da
Subunit: Interacts with BACE1. Interacts with APP. Interacts with STMN2
Subcellular location: Lysosome membrane; Single-pass type II membrane protein (By similarity). Cell membrane;Single-pass type II membrane protein
Secondary accessions: B3KPG4 Q4G0A8 Q53H84 Q6IAE7 Q86VK5 Q8N288 Q8TAW0 Q9BUP8Alternative splicing: 3 isoforms: Q9NQX7-1 Q9NQX7-2 Q9NQX7-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ITM2C: NX_Q9NQX7
Post-translational modifications:
Type I membrane-bound, as well as soluble, furin has a pre-eminent role in ITM2C proteolytic processing. PCSK7 andPCSK5 may also be involved although to a lesser extent. The soluble form of PCSK7 is incapable of processing ITM2C.Fails to undergo shedding by ADAM10 and intramembanaire cleavage by SPPL2B1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NQX7 ITM2C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001012532.1 NP_001012534.1 NP_112188.1 ENSEMBL proteins: ENSP00000390655 ENSP00000440295 ENSP00000322730 ENSP00000335121 ENSP00000322100 ENSP00000444899 ENSP00000387242 ENSP00000403257 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
ITM2C for ontologies About GeneDecksing
ITM2C Antibody Products: Assay Products for ITM2C: |
Protein
Domains / Families for ITM2C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ITM2C for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NQX7ProtoNet protein and cluster: Q9NQX7 1 Blocks protein family: IPB007084 BRICHOS domain
UniProtKB/Swiss-Prot: ITM2C_HUMAN, Q9NQX7Similarity: Belongs to the ITM2 familySimilarity: Contains 1 BRICHOS domain |
Function for ITM2C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ITM2C_HUMAN, Q9NQX7Function: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking itsaccess to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible,suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death andneuronal differentiation (By similarity)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITM2C (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITM2C (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ITM2C (NM_030926) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ITM2C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITM2C  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITM2C |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ITM2C for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ITM2C:
|
Pathways & Interactions for ITM2C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ITM2C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
 5/9 Interacting proteins for ITM2C (Q9NQX72, 3 ENSP000003227304) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0010977 | negative regulation of neuron projection development |
IDA | 18452648 | | GO:0012502 | induction of programmed cell death |
IEA | -- | | GO:0030182 | neuron differentiation |
ISS | -- |
ITM2C for ontologies About GeneDecksing
|
Drugs & Compounds for ITM2C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ITM2C Search CenterWatch for drugs/clinical trials and news about ITM2C 
|
Transcripts for ITM2C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ITM2C gene (3 alternative transcripts): NM_001012514.1 NM_001012516.1 NM_030926.4 Unigene Cluster for ITM2C: Integral membrane protein 2C Hs.111577 [show with all ESTs]Unigene Representative Sequence: NM_0309269 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000457215 ENST00000541852 ENST00000326427(uc002vqz.3 uc002vra.3 uc002vrb.3) ENST00000335005(uc002vrc.3) ENST00000326407(uc002vrd.3) ENST00000543957 ENST00000409704 ENST00000418408 ENST00000492029
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITM2C (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITM2C (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ITM2C (NM_030926) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ITM2C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITM2C  |
Additional cDNA sequence: AB003629.1 AF271781.1 AF272043.1 AK056321.1 AK075361.1 AK090975.1 AK222697.1 AK295503.1 AK303199.1 AK307702.1 AL136603.1 AL713651.1 AY049777.1 BC002424.1 BC025742.1 BC050668.1 BC098563.1 CR457208.1 D87062.1 24/33 DOTS entries (see all 33): DT.100679059 DT.100679057 DT.87017388 DT.100679055 DT.121003813 DT.100679056 DT.95121925 DT.92390033 DT.102835676 DT.97799430 DT.95323346 DT.100862614 DT.100865245 DT.100868461 DT.100868474 DT.121003826 DT.100870988 DT.121003780 DT.121003824 DT.121003834 DT.100676513 DT.100679067 DT.100683566 DT.100856823 24/676 AceView cDNA sequences (see all 676): BQ879617 BG912025 BQ017300 NM_030926 CN478648 AA593814 AI077778 BU631822 BF981426 BQ434277 BU740008 BM709442 CK904353 AF272043 BM749980 CF131614 CR598205 AK075361 AA907485 AY049777 AW051214 BG056353 AA985619 AA158691 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ITM2C About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ITM2C
|
Expression for ITM2C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ITM2C expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTTTTACTGA
About this image See ITM2C Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ITM2C
SOURCE GeneReport for Unigene cluster: Hs.111577 UniProtKB/Swiss-Prot: ITM2C_HUMAN, Q9NQX7Tissue specificity: High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus,thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs SABiosciences Custom PCR Arrays for ITM2C
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ITM2C Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ITM2C | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITM2C | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITM2C | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITM2C |
Orthologs for ITM2C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ITM2C gene from 6/13 species (see all 13) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
ITM2C1 |
integral membrane protein 2C |
70.88(n) 68.97(a) |
  |
424831 XM_422643.3 XP_422643.3 |
lizard (Anolis carolinensis) |
Reptilia |
ITM2C6 |
-- |
55(a) |
1 ↔ 1 |
3(28254734-28260310) |
African clawed frog (Xenopus laevis) |
Amphibia |
BI446652.12 |
-- |
82.03(n) |
  |
BI446652.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufj35c022 |
wufj35c02 |
75.6(n) |
  |
335863 BC054689.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG36626 |
-- |
16(a) |
1 → many |
2L(821422-824337) |
worm (Caenorhabditis elegans) |
Secernentea |
C25F6.76 |
Protein C25F6.7, isoform b |
15(a) |
1 → many |
X(5445037-5447998) |
ENSEMBL Gene Tree for ITM2C (if available) TreeFam Gene Tree for ITM2C (if available)  |
Paralogs for ITM2C gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ITM2C gene
- ITM2B2 ITM2A2
2 SIMAP similar genes for ITM2C using alignment to 5 protein entries: ITM2C_HUMAN (see all proteins):ITM2B ITM2A
ITM2C for paralogs About GeneDecksing
|
Genomic Variants for ITM2C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 2 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ITM2C (231729354 - 231743963 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ITM2C: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITM2C |
|
Disorders
/ Diseases for ITM2C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ITM2C for disorders About GeneDecksing
OMIM gene information: 609554
OMIM disorders: --
6 diseases for ITM2C: About MalaCardscerebritis anemia of prematurity anemia dementia influenza neuronitis Human Genome Epidemiology (HuGE) Navigator: ITM2C (2 documents) Export disorders for ITM2C gene to outside databases
|
Publications for ITM2C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ITM2C gene, integrated from 9 sources (see all 36): (articles sorted by number of sources associating them with ITM2C) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis. (PubMed id 19114711)1, 2 Martin L....Haass C. (2009)
- BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2. (PubMed id 19366692)1, 2 Matsuda S....D'Adamio L. (2009)
- BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells. (PubMed id 18452648)1, 2 Gong Y....Yuan J. (2008)
- Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin. (PubMed id 15606899)1, 2 Wickham L.... Seidah N.G. (2005)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Sequence, genomic structure and tissue expression of human BRI3, a member of the BRI gene family. (PubMed id 11290423)1, 2 Vidal R.... Frangione B. (2001)
- Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning. (PubMed id 9653160)1, 3 Mao M.... Chen Z. (1998)
|
External Searches for ITM2C gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ITM2C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ITM2C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ITM2C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ITM2C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ITM2C gene: Search GeneIP for patents involving ITM2C
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ITM2C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ITM2C | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITM2C | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITM2C | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITM2C | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITM2C | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITM2C |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITM2C |
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| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITM2C |
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